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The map label for this gene is clpX

Identifier: 89055298

GI number: 89055298

Start: 2821260

End: 2822525

Strand: Reverse

Name: clpX

Synonym: Jann_2807

Alternate gene names: 89055298

Gene position: 2822525-2821260 (Counterclockwise)

Preceding gene: 89055299

Following gene: 89055292

Centisome position: 65.37

GC content: 56.48

Gene sequence:

>1266_bases
ATGGCAAGTAACTCCGGCAACGATTCCAAGAATACGCTCTATTGCTCATTCTGCGGCAAGAGCCAGCATGAGGTGCGCAA
GCTGATCGCGGGCCCCACGGTGTTTATCTGCGACGAATGCGTCGAACTCTGCATGGATATCATTCGCGAGGAAACCAAAA
GCGCAGGTCTGAAAAGCGATGATGGCGTGCCGACCCCGCAAGAAATCTGCGGTGTGTTGGATGATTACGTGATCGGCCAA
GCCCACGCCAAGCGCGTGTTGTCGGTGGCTGTGCATAACCACTATAAACGCTTGAATCATTCGGATAAATCCGACATCGA
ACTGGCCAAATCCAACATCATGCTGATCGGTCCCACCGGGTGCGGCAAGACGCTGCTGGCTCAGACCTTAGCGCGCATCC
TTGATGTGCCGTTCACGATGGCTGATGCGACGACGCTGACGGAAGCGGGCTATGTCGGAGAGGATGTGGAAAACATTATC
CTCAAGCTCCTGCAGGCGTCCGAGTATAATGTGGAACGGGCCCAACGCGGCATTGTCTACATCGATGAAGTCGATAAAAT
CACACGCAAATCTGACAATCCGTCCATCACCCGCGATGTCTCGGGCGAGGGGGTTCAGCAGGCGTTGCTGAAGATTATGG
AGGGCACCGTGGCCTCCGTGCCGCCCCAGGGGGGGCGCAAGCATCCGCAGCAGGAATTCCTGCAAGTGGACACGACGAAT
ATCCTGTTCATTTGTGGCGGCGCGTTTGCGGGTCTTGATAAGATCATCGCGCAGCGCGGCAAAGGCTCTGCCATGGGGTT
CGGGGCCGATGTCCGTGACCCAGATTCCAAGTCCGTGGGGGAATACTTCAAGGATCTGGAGCCTGAGGATTTGCTGAAAT
TCGGCCTGATCCCTGAATTTGTTGGCCGCCTTCCGGTCATCGCGACGCTGGAAGATCTGGATGAAGACGCTCTGGTCACG
ATCCTGACGGGTCCGAAGAACGCGTTGGTCAAACAATACCAGCGCTTGTTTGAGCTTGAAGACGTCAAACTGACATTTAC
CGACGATGCCATGAGCGCGATCGCCAAGCGTGCGATTTTGCGCAAGACCGGCGCGCGGGGATTGCGCTCGATCATGGAAG
ACATCCTGCTGGACACCATGTTCGACATGCCCGGAGCGGAGGGCGTTGAAGAGGTTGTGGTCAACGAAGAGGCGGTGAAT
TCAGACACACAGCCGCTGATGATTTACGCCGAGCGTAAGGCAGATGAGCCGGCGTCGGCCAGCTGA

Upstream 100 bases:

>100_bases
GACCGGGGCAGGCCTGTTCTAGGCTGGTGCAAGGCCGGTAGAATGACTGGCGGTTCGCGGCAATTCTGCCGCTTGAGGGC
CCCGCGTAAGGTGGACGAAT

Downstream 100 bases:

>100_bases
TCCTACTGATTTTCCTTAAGAATTGCCCCAGCCCGAAACGGGCCGGGATGACATCCTTGGTGCTTGGTGTAGATCTGAGC
CCACATCCTACGGGTCAGCG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MASNSGNDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKSAGLKSDDGVPTPQEICGVLDDYVIGQ
AHAKRVLSVAVHNHYKRLNHSDKSDIELAKSNIMLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQASEYNVERAQRGIVYIDEVDKITRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLDKIIAQRGKGSAMGFGADVRDPDSKSVGEYFKDLEPEDLLKFGLIPEFVGRLPVIATLEDLDEDALVT
ILTGPKNALVKQYQRLFELEDVKLTFTDDAMSAIAKRAILRKTGARGLRSIMEDILLDTMFDMPGAEGVEEVVVNEEAVN
SDTQPLMIYAERKADEPASAS

Sequences:

>Translated_421_residues
MASNSGNDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKSAGLKSDDGVPTPQEICGVLDDYVIGQ
AHAKRVLSVAVHNHYKRLNHSDKSDIELAKSNIMLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQASEYNVERAQRGIVYIDEVDKITRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLDKIIAQRGKGSAMGFGADVRDPDSKSVGEYFKDLEPEDLLKFGLIPEFVGRLPVIATLEDLDEDALVT
ILTGPKNALVKQYQRLFELEDVKLTFTDDAMSAIAKRAILRKTGARGLRSIMEDILLDTMFDMPGAEGVEEVVVNEEAVN
SDTQPLMIYAERKADEPASAS
>Mature_420_residues
ASNSGNDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKSAGLKSDDGVPTPQEICGVLDDYVIGQA
HAKRVLSVAVHNHYKRLNHSDKSDIELAKSNIMLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIIL
KLLQASEYNVERAQRGIVYIDEVDKITRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNI
LFICGGAFAGLDKIIAQRGKGSAMGFGADVRDPDSKSVGEYFKDLEPEDLLKFGLIPEFVGRLPVIATLEDLDEDALVTI
LTGPKNALVKQYQRLFELEDVKLTFTDDAMSAIAKRAILRKTGARGLRSIMEDILLDTMFDMPGAEGVEEVVVNEEAVNS
DTQPLMIYAERKADEPASAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=342, Percent_Identity=50.5847953216374, Blast_Score=314, Evalue=8e-86,
Organism=Escherichia coli, GI1786642, Length=422, Percent_Identity=68.4834123222749, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1790366, Length=120, Percent_Identity=40.8333333333333, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=333, Percent_Identity=45.6456456456456, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=333, Percent_Identity=45.6456456456456, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=37.9134860050891, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=38.8663967611336, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=38.0281690140845, Blast_Score=265, Evalue=7e-72,
Organism=Drosophila melanogaster, GI24648289, Length=335, Percent_Identity=49.5522388059701, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI24648291, Length=335, Percent_Identity=49.5522388059701, Blast_Score=305, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_JANSC (Q28NI8)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510749.1
- ProteinModelPortal:   Q28NI8
- STRING:   Q28NI8
- GeneID:   3935273
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2807
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q28NI8
- ProtClustDB:   PRK05342
- BioCyc:   JSP290400:JANN_2807-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45888; Mature: 45757

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNSGNDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKSAGLKSD
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGVPTPQEICGVLDDYVIGQAHAKRVLSVAVHNHYKRLNHSDKSDIELAKSNIMLIGPTG
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCC
CGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASEYNVERAQRGIVY
CCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEVDKITRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
EECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCCC
ILFICGGAFAGLDKIIAQRGKGSAMGFGADVRDPDSKSVGEYFKDLEPEDLLKFGLIPEF
EEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHH
VGRLPVIATLEDLDEDALVTILTGPKNALVKQYQRLFELEDVKLTFTDDAMSAIAKRAIL
HCCCCEEHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
RKTGARGLRSIMEDILLDTMFDMPGAEGVEEVVVNEEAVNSDTQPLMIYAERKADEPASA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCCCCCEEEEEECCCCCCCCC
S
C
>Mature Secondary Structure 
ASNSGNDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKSAGLKSD
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DGVPTPQEICGVLDDYVIGQAHAKRVLSVAVHNHYKRLNHSDKSDIELAKSNIMLIGPTG
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCC
CGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASEYNVERAQRGIVY
CCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCEE
IDEVDKITRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
EECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCCC
ILFICGGAFAGLDKIIAQRGKGSAMGFGADVRDPDSKSVGEYFKDLEPEDLLKFGLIPEF
EEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHH
VGRLPVIATLEDLDEDALVTILTGPKNALVKQYQRLFELEDVKLTFTDDAMSAIAKRAIL
HCCCCEEHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
RKTGARGLRSIMEDILLDTMFDMPGAEGVEEVVVNEEAVNSDTQPLMIYAERKADEPASA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCCCCCEEEEEECCCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA