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The map label for this gene is mraY

Identifier: 89055255

GI number: 89055255

Start: 2778864

End: 2779943

Strand: Reverse

Name: mraY

Synonym: Jann_2764

Alternate gene names: 89055255

Gene position: 2779943-2778864 (Counterclockwise)

Preceding gene: 89055256

Following gene: 89055254

Centisome position: 64.38

GC content: 60.09

Gene sequence:

>1080_bases
ATGTTGTATTGGCTCAATGAACTCTCGGATGGCGGCGATGTCTTCAACCTGTTCCGGTACATCACGTTCCGAGCCGGGGG
CGCGTTCTTCACCGCGCTGATTTTTGGCTTCATTTTCGGACAACCGCTGATCAATGCTTTGCGGCGCAAATACAAGGACG
GCCAGCCCATCCGTGAAGTGGGCCCGGCCCATGAAACCAAGGCGGGCACCCCCACCATGGGAGGGTTGCTGATCTTGGCG
GCGCTTAGCCTTGCGACGCTGCTTTGGGCGCGGCTGGATAACCCCTATGTCTGGCTCGTGCTCGGTGTCACCTGGTGTTT
TGGCCTGATCGGATTTGCCGATGACTGGGCCAAGGTCAGCCGCAACTCCAGCGCGGGCGTCTCGGGCAAGGTGCGCCTGG
CGATCGGCTTTGTGGTGGCGTTTGGCGCGGCCCTGATCGCGGCCTGGGTGCACCCCGAGGAGTTGTCCAACCAATTGGCA
ATGCCCGTCTTCAAGGATGTTTTGCTGAATATGGGCTGGATGTATGTGCCCTTCGTGATGATCGTGATCGTAGGCTCGGC
CAACGCGGTCAACCTGACCGACGGCCTTGACGGGCTGGCGATCATGCCGGTGATGATTGCCGCAGGCACCCTGGGGGTCA
TCGCCTATGCGGTGGGCCGCGTGGACTTTACCGATTACCTCGACGTGCATTACGTCCCCGGCACCGGTGAATTATTGATC
TTCACGGCCGGGTTGATTGGCGGCGGCCTGGGCTTCTTGTGGTACAATGCGCCGCCAGCAGCCGTGTTCATGGGCGACAC
AGGTTCGCTTGCCCTGGGCGGCGCGCTTGGCGCGATTGCGGTTTGCACCAAGCATGAAATCGTCCTTGCGATCGTCGGCG
GCCTGTTTGTGGCTGAGGCGGTGTCGGTCATCGTGCAGGTTCTTTACTTCAAGGCGACGGGAAAACGCGTGTTCCTTATG
GCCCCGATCCACCACCATTTTGAGAAGAAGGGATGGGCAGAGCCGCAGGTCGTAATCCGCTTCTGGATCATCTCGCTGAT
CCTGGCGTTGATCGGTCTGGCCACGTTGAAATTGCGGTAG

Upstream 100 bases:

>100_bases
GCTGGTCAAGGGGTCCAAGGGCTCTCGCGTGTCGCTGGTGGTTGACGCCCTTCGGAAACTGGGGCAATCGCTTGAGCGCG
CAGGGCAAGGAAACCGCTAG

Downstream 100 bases:

>100_bases
CGGTCCGGACCCTGGTCAAATTGAGACGCCGTTGGCGTCATTCGATACTTTGTTTGGCGTTTGGGGCCGGTGGCGCGGCG
TAACCGTGGTCCGGATCGAG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MLYWLNELSDGGDVFNLFRYITFRAGGAFFTALIFGFIFGQPLINALRRKYKDGQPIREVGPAHETKAGTPTMGGLLILA
ALSLATLLWARLDNPYVWLVLGVTWCFGLIGFADDWAKVSRNSSAGVSGKVRLAIGFVVAFGAALIAAWVHPEELSNQLA
MPVFKDVLLNMGWMYVPFVMIVIVGSANAVNLTDGLDGLAIMPVMIAAGTLGVIAYAVGRVDFTDYLDVHYVPGTGELLI
FTAGLIGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVAEAVSVIVQVLYFKATGKRVFLM
APIHHHFEKKGWAEPQVVIRFWIISLILALIGLATLKLR

Sequences:

>Translated_359_residues
MLYWLNELSDGGDVFNLFRYITFRAGGAFFTALIFGFIFGQPLINALRRKYKDGQPIREVGPAHETKAGTPTMGGLLILA
ALSLATLLWARLDNPYVWLVLGVTWCFGLIGFADDWAKVSRNSSAGVSGKVRLAIGFVVAFGAALIAAWVHPEELSNQLA
MPVFKDVLLNMGWMYVPFVMIVIVGSANAVNLTDGLDGLAIMPVMIAAGTLGVIAYAVGRVDFTDYLDVHYVPGTGELLI
FTAGLIGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVAEAVSVIVQVLYFKATGKRVFLM
APIHHHFEKKGWAEPQVVIRFWIISLILALIGLATLKLR
>Mature_359_residues
MLYWLNELSDGGDVFNLFRYITFRAGGAFFTALIFGFIFGQPLINALRRKYKDGQPIREVGPAHETKAGTPTMGGLLILA
ALSLATLLWARLDNPYVWLVLGVTWCFGLIGFADDWAKVSRNSSAGVSGKVRLAIGFVVAFGAALIAAWVHPEELSNQLA
MPVFKDVLLNMGWMYVPFVMIVIVGSANAVNLTDGLDGLAIMPVMIAAGTLGVIAYAVGRVDFTDYLDVHYVPGTGELLI
FTAGLIGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVAEAVSVIVQVLYFKATGKRVFLM
APIHHHFEKKGWAEPQVVIRFWIISLILALIGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=50.6925207756233, Blast_Score=328, Evalue=4e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_JANSC (Q28NN1)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510706.1
- STRING:   Q28NN1
- GeneID:   3935228
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2764
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q28NN1
- ProtClustDB:   PRK00108
- BioCyc:   JSP290400:JANN_2764-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38574; Mature: 38574

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10b741a8)-; HASH(0x1226c868)-; HASH(0x122345c8)-; HASH(0x12246104)-; HASH(0x122344f0)-; HASH(0x122345e0)-; HASH(0x12226478)-; HASH(0x11f2ce44)-; HASH(0x12226418)-; HASH(0x12269e64)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYWLNELSDGGDVFNLFRYITFRAGGAFFTALIFGFIFGQPLINALRRKYKDGQPIREV
CEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHC
GPAHETKAGTPTMGGLLILAALSLATLLWARLDNPYVWLVLGVTWCFGLIGFADDWAKVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
RNSSAGVSGKVRLAIGFVVAFGAALIAAWVHPEELSNQLAMPVFKDVLLNMGWMYVPFVM
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IVIVGSANAVNLTDGLDGLAIMPVMIAAGTLGVIAYAVGRVDFTDYLDVHYVPGTGELLI
HHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEE
FTAGLIGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVAEA
EEHHHHHCCCEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VSVIVQVLYFKATGKRVFLMAPIHHHFEKKGWAEPQVVIRFWIISLILALIGLATLKLR
HHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLYWLNELSDGGDVFNLFRYITFRAGGAFFTALIFGFIFGQPLINALRRKYKDGQPIREV
CEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHC
GPAHETKAGTPTMGGLLILAALSLATLLWARLDNPYVWLVLGVTWCFGLIGFADDWAKVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
RNSSAGVSGKVRLAIGFVVAFGAALIAAWVHPEELSNQLAMPVFKDVLLNMGWMYVPFVM
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IVIVGSANAVNLTDGLDGLAIMPVMIAAGTLGVIAYAVGRVDFTDYLDVHYVPGTGELLI
HHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEE
FTAGLIGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVAEA
EEHHHHHCCCEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VSVIVQVLYFKATGKRVFLMAPIHHHFEKKGWAEPQVVIRFWIISLILALIGLATLKLR
HHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA