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The map label for this gene is murG

Identifier: 89055251

GI number: 89055251

Start: 2774392

End: 2775495

Strand: Reverse

Name: murG

Synonym: Jann_2760

Alternate gene names: 89055251

Gene position: 2775495-2774392 (Counterclockwise)

Preceding gene: 89055252

Following gene: 89055250

Centisome position: 64.28

GC content: 67.21

Gene sequence:

>1104_bases
ATGTCCAAACCCCACCTCATCATCGCGGCAGGCGGCACCGGCGGGCACATGTTCCCCGCCCAGGCCCTGTCCGAGGCGAT
GTTGCGGAAGGGCTGGCGTGTGACGCTGTCGACCGATGCGCGGGGCGCGCGGTATGTGGGCGGATTTTCCCACGCGGTGG
AGATCCGGGAGGTGTCCTCGGCCACGTTCACGCGGGGCGGGGCGCTGGCGAAGCTGGCGGTTCCTTTCCGCATCTTCGGC
GGAGTTCTGACCGCGACCGCGCGAATGCTCCGCGAAAAGCCCGACGTCGTTGTGGGCTTTGGCGGTTATCCGACAATCCC
GGCCATGGCGGCGGCGCGGCTGACGGGACGGCCCCGGATGTTGCACGAACAGAATGGCGTTTTAGGCCGCGTGAACCGCG
TCTTCGCGAAACACGTCGCCCATGTGGCCTGTGGCACCTGGCCCACCGATGTGCCCTTGGGCGCAGACGCCATTCACACG
GGCAACCCGGTCCGCGCGGCCATCGTTGAGCGGGGCGGCGCCCCCTACACGCCACCGGGCGATTGGCCGATGAGCCTTTT
GGTGTTCGGCGGCAGCCAGGGCGCGCGGATCCTCTCGGACGTGGTGCCCGCCGCCATTGCTTTGCTGCCCGAGGCCATCC
GGGACCTGTTGCGCATCGCGCAGCAGGCGCGGGAAGAAGATGTCGACCGCGTGCAAGCGGCCTATGATGACCTGTCCATG
CGGGTGGAGGTGGACACCTTCCTCCACGACATGCCCCGTCGTCTGTCAGAGGCGCAATTGGTCATCTGCCGCTCCGGCGC
ATCGTCCGTTGCCGATATCAACGTTGTGGGCCGCCCCGCGATCTACGTGCCATTGGCCATTGCCGTGCGCGATGAGCAGA
CCGCCAATGCGCGCGGTCCCGTGGATGCGGGCGCCGCCGTCCTGATGCCCGAAAGTCAGCTGACACCTGAAACGCTGGCC
CAGACCATCGAGCAGATCCTCACCCAGCCCGATGCGGCCACACAGATGTCTATCGCCGCGCTTTCCGTGGCCGTGCCCGA
CGCAACGGAACGTCTCGTGGCGCTTGTCGAAACGCTTGCCGCCCCCACACCACAGGAAACCTGA

Upstream 100 bases:

>100_bases
ATCGCGACGGGGATTGCAGTCGGCATGCTTCTGGTGTTCACCCGCACCCGTCCCCAAGGCGATATCGCCGATCACCTCCT
GTCACGCCAACGGTAGTTTC

Downstream 100 bases:

>100_bases
GCCATGAACGCCGCCGCCACCAAATTACCGACCCAACTGGGCTCCATCCACTTTGTGGGCATCGGCGGCATCGGCATGTC
GGGCATTGCCGAGGTGCTGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSKPHLIIAAGGTGGHMFPAQALSEAMLRKGWRVTLSTDARGARYVGGFSHAVEIREVSSATFTRGGALAKLAVPFRIFG
GVLTATARMLREKPDVVVGFGGYPTIPAMAAARLTGRPRMLHEQNGVLGRVNRVFAKHVAHVACGTWPTDVPLGADAIHT
GNPVRAAIVERGGAPYTPPGDWPMSLLVFGGSQGARILSDVVPAAIALLPEAIRDLLRIAQQAREEDVDRVQAAYDDLSM
RVEVDTFLHDMPRRLSEAQLVICRSGASSVADINVVGRPAIYVPLAIAVRDEQTANARGPVDAGAAVLMPESQLTPETLA
QTIEQILTQPDAATQMSIAALSVAVPDATERLVALVETLAAPTPQET

Sequences:

>Translated_367_residues
MSKPHLIIAAGGTGGHMFPAQALSEAMLRKGWRVTLSTDARGARYVGGFSHAVEIREVSSATFTRGGALAKLAVPFRIFG
GVLTATARMLREKPDVVVGFGGYPTIPAMAAARLTGRPRMLHEQNGVLGRVNRVFAKHVAHVACGTWPTDVPLGADAIHT
GNPVRAAIVERGGAPYTPPGDWPMSLLVFGGSQGARILSDVVPAAIALLPEAIRDLLRIAQQAREEDVDRVQAAYDDLSM
RVEVDTFLHDMPRRLSEAQLVICRSGASSVADINVVGRPAIYVPLAIAVRDEQTANARGPVDAGAAVLMPESQLTPETLA
QTIEQILTQPDAATQMSIAALSVAVPDATERLVALVETLAAPTPQET
>Mature_366_residues
SKPHLIIAAGGTGGHMFPAQALSEAMLRKGWRVTLSTDARGARYVGGFSHAVEIREVSSATFTRGGALAKLAVPFRIFGG
VLTATARMLREKPDVVVGFGGYPTIPAMAAARLTGRPRMLHEQNGVLGRVNRVFAKHVAHVACGTWPTDVPLGADAIHTG
NPVRAAIVERGGAPYTPPGDWPMSLLVFGGSQGARILSDVVPAAIALLPEAIRDLLRIAQQAREEDVDRVQAAYDDLSMR
VEVDTFLHDMPRRLSEAQLVICRSGASSVADINVVGRPAIYVPLAIAVRDEQTANARGPVDAGAAVLMPESQLTPETLAQ
TIEQILTQPDAATQMSIAALSVAVPDATERLVALVETLAAPTPQET

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=364, Percent_Identity=34.8901098901099, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_JANSC (Q28NN5)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510702.1
- ProteinModelPortal:   Q28NN5
- SMR:   Q28NN5
- STRING:   Q28NN5
- GeneID:   3935224
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2760
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q28NN5
- ProtClustDB:   PRK00726
- BioCyc:   JSP290400:JANN_2760-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38802; Mature: 38671

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPHLIIAAGGTGGHMFPAQALSEAMLRKGWRVTLSTDARGARYVGGFSHAVEIREVSS
CCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEECCHHHHHHHHHHCC
ATFTRGGALAKLAVPFRIFGGVLTATARMLREKPDVVVGFGGYPTIPAMAAARLTGRPRM
HHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCH
LHEQNGVLGRVNRVFAKHVAHVACGTWPTDVPLGADAIHTGNPVRAAIVERGGAPYTPPG
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCCC
DWPMSLLVFGGSQGARILSDVVPAAIALLPEAIRDLLRIAQQAREEDVDRVQAAYDDLSM
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHE
RVEVDTFLHDMPRRLSEAQLVICRSGASSVADINVVGRPAIYVPLAIAVRDEQTANARGP
EEEHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCEEEEEEEEEEECCCCCCCCCC
VDAGAAVLMPESQLTPETLAQTIEQILTQPDAATQMSIAALSVAVPDATERLVALVETLA
CCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHC
APTPQET
CCCCCCC
>Mature Secondary Structure 
SKPHLIIAAGGTGGHMFPAQALSEAMLRKGWRVTLSTDARGARYVGGFSHAVEIREVSS
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEECCHHHHHHHHHHCC
ATFTRGGALAKLAVPFRIFGGVLTATARMLREKPDVVVGFGGYPTIPAMAAARLTGRPRM
HHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCH
LHEQNGVLGRVNRVFAKHVAHVACGTWPTDVPLGADAIHTGNPVRAAIVERGGAPYTPPG
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCCC
DWPMSLLVFGGSQGARILSDVVPAAIALLPEAIRDLLRIAQQAREEDVDRVQAAYDDLSM
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHE
RVEVDTFLHDMPRRLSEAQLVICRSGASSVADINVVGRPAIYVPLAIAVRDEQTANARGP
EEEHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCEEEEEEEEEEECCCCCCCCCC
VDAGAAVLMPESQLTPETLAQTIEQILTQPDAATQMSIAALSVAVPDATERLVALVETLA
CCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHC
APTPQET
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA