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The map label for this gene is dhmA2 [H]

Identifier: 89055116

GI number: 89055116

Start: 2642815

End: 2643759

Strand: Direct

Name: dhmA2 [H]

Synonym: Jann_2625

Alternate gene names: 89055116

Gene position: 2642815-2643759 (Clockwise)

Preceding gene: 89055115

Following gene: 89055122

Centisome position: 61.2

GC content: 60.74

Gene sequence:

>945_bases
ATGACCGGCGTCTTTGACGCGGCCCACGGCCGCGCGCAAGCAACGGTCGCACGTTTGGGCATCGGCGCAGAGTATCGGTT
TGCGCATCATTTCGCCCACACGCCCATGGGCACGATGCACTACGTGGACGAAGGGACCGGCGACCCTGTCCTACTGCTGC
ACGGCAATCCGACATGGTCTTACCTCTACCGCAAATTCATCCCCGCCCTTGCACAGACCCATCGCGTGATCGCCCCCGAT
CACATCGGTTTTGGCCTGTCGGACAAACCCGAGGCGGAGGGTGACTATACGCTAGACGCGCATATCCAAAACCTTGAGGC
TCTGGTGCAGCAGCTTGACCTGACCAACATCACGCTTGTGATGCAGGATTGGGGCGGGCCCATCGGCCTTGGCATGGCGG
CCCGGCATCCCGCCCGCATCAAGGCGCTGGTGGTAATGAAAACTTTTGGCTTCTACCCGCCGATTGATGGGGTCGATCCC
GACAAGCTGAAACTCCCCCCGCCGCTGTTGATGATGCGGGCAAAGGGCATCGGTGATTTTCTGGTGCGACGCCTGGGGTT
CTTTGAACGTCAGGTCATGACCATGGCCACGGCGACCAAACGCAAAGGCCCGTCCAAGCGTGCCTACCGCGACATCTTTC
GCACCTACGCCGAACGCGCGGGCGTCATGGCCTTTCCGCGCATGATCCCGGCCAACACGGGCCACCCAGCTGCACAGATC
CTGATGCAAGAAACCGGCCCCTATATCGACCAGTTCGACGGTCCTGCGCATATCTTCTGGGGCATGAAAGATCCGTTGAT
CCCGGTCGGCGCTCTTACCGCATGGAAGAAACGGCTGCCCCAGGCAGGCGTCACCGAGTTCGCGACCGCGCGGCACTACC
TTCAGGACGACGTACCGGACCAATTGATCCCGGAACTTGTCGAATTTTTGAACCGGGACGTCTAA

Upstream 100 bases:

>100_bases
CAAAGGAAGACCAGAACCTGAACAGTGCTAACCTAAATTAGCGGACTCCAAGGGGAGCAGGTCACACCCAACTGGGCAAA
ATCGTCGTGGAGATGGATCA

Downstream 100 bases:

>100_bases
GAGAGTGTCCCATTCACGGACCAAACCGCGGCAGAGATCGAAACGATCTTTATCTTCACACCGGTCTTTCAGTCACCTGC
GATCTCATCACAGATGACTG

Product: alpha/beta hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTGVFDAAHGRAQATVARLGIGAEYRFAHHFAHTPMGTMHYVDEGTGDPVLLLHGNPTWSYLYRKFIPALAQTHRVIAPD
HIGFGLSDKPEAEGDYTLDAHIQNLEALVQQLDLTNITLVMQDWGGPIGLGMAARHPARIKALVVMKTFGFYPPIDGVDP
DKLKLPPPLLMMRAKGIGDFLVRRLGFFERQVMTMATATKRKGPSKRAYRDIFRTYAERAGVMAFPRMIPANTGHPAAQI
LMQETGPYIDQFDGPAHIFWGMKDPLIPVGALTAWKKRLPQAGVTEFATARHYLQDDVPDQLIPELVEFLNRDV

Sequences:

>Translated_314_residues
MTGVFDAAHGRAQATVARLGIGAEYRFAHHFAHTPMGTMHYVDEGTGDPVLLLHGNPTWSYLYRKFIPALAQTHRVIAPD
HIGFGLSDKPEAEGDYTLDAHIQNLEALVQQLDLTNITLVMQDWGGPIGLGMAARHPARIKALVVMKTFGFYPPIDGVDP
DKLKLPPPLLMMRAKGIGDFLVRRLGFFERQVMTMATATKRKGPSKRAYRDIFRTYAERAGVMAFPRMIPANTGHPAAQI
LMQETGPYIDQFDGPAHIFWGMKDPLIPVGALTAWKKRLPQAGVTEFATARHYLQDDVPDQLIPELVEFLNRDV
>Mature_313_residues
TGVFDAAHGRAQATVARLGIGAEYRFAHHFAHTPMGTMHYVDEGTGDPVLLLHGNPTWSYLYRKFIPALAQTHRVIAPDH
IGFGLSDKPEAEGDYTLDAHIQNLEALVQQLDLTNITLVMQDWGGPIGLGMAARHPARIKALVVMKTFGFYPPIDGVDPD
KLKLPPPLLMMRAKGIGDFLVRRLGFFERQVMTMATATKRKGPSKRAYRDIFRTYAERAGVMAFPRMIPANTGHPAAQIL
MQETGPYIDQFDGPAHIFWGMKDPLIPVGALTAWKKRLPQAGVTEFATARHYLQDDVPDQLIPELVEFLNRDV

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=318, Percent_Identity=25.4716981132075, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562298, Length=307, Percent_Identity=24.1042345276873, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554012, Length=306, Percent_Identity=21.2418300653595, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324392, Length=104, Percent_Identity=34.6153846153846, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 34948; Mature: 34817

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVFDAAHGRAQATVARLGIGAEYRFAHHFAHTPMGTMHYVDEGTGDPVLLLHGNPTWS
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHH
YLYRKFIPALAQTHRVIAPDHIGFGLSDKPEAEGDYTLDAHIQNLEALVQQLDLTNITLV
HHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEE
MQDWGGPIGLGMAARHPARIKALVVMKTFGFYPPIDGVDPDKLKLPPPLLMMRAKGIGDF
EECCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHH
LVRRLGFFERQVMTMATATKRKGPSKRAYRDIFRTYAERAGVMAFPRMIPANTGHPAAQI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHH
LMQETGPYIDQFDGPAHIFWGMKDPLIPVGALTAWKKRLPQAGVTEFATARHYLQDDVPD
HHHHCCCHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCH
QLIPELVEFLNRDV
HHHHHHHHHHCCCC
>Mature Secondary Structure 
TGVFDAAHGRAQATVARLGIGAEYRFAHHFAHTPMGTMHYVDEGTGDPVLLLHGNPTWS
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCHHH
YLYRKFIPALAQTHRVIAPDHIGFGLSDKPEAEGDYTLDAHIQNLEALVQQLDLTNITLV
HHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEE
MQDWGGPIGLGMAARHPARIKALVVMKTFGFYPPIDGVDPDKLKLPPPLLMMRAKGIGDF
EECCCCCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHH
LVRRLGFFERQVMTMATATKRKGPSKRAYRDIFRTYAERAGVMAFPRMIPANTGHPAAQI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCHHHHH
LMQETGPYIDQFDGPAHIFWGMKDPLIPVGALTAWKKRLPQAGVTEFATARHYLQDDVPD
HHHHCCCHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCH
QLIPELVEFLNRDV
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]