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The map label for this gene is hbpA [H]

Identifier: 89054954

GI number: 89054954

Start: 2456799

End: 2458466

Strand: Direct

Name: hbpA [H]

Synonym: Jann_2463

Alternate gene names: 89054954

Gene position: 2456799-2458466 (Clockwise)

Preceding gene: 89054953

Following gene: 89054955

Centisome position: 56.9

GC content: 63.37

Gene sequence:

>1668_bases
ATGAAAGATTTCACCCACACGACCACGCAAGTCCAACAGCAGGGCGGGCTCACGACCCATCCGGTCGCCGAGATGTATGC
CGCCGAGCATAAGGCCGGTCGCCTTGACCGCCGCGAATTCCTCGTGCGCTCCACCGCTCTGGGCCTCAGCGCCGCCGCCG
CCTATTCGCTGATCGGGGCCACGCCCGCCATGGCCGACGGCCACCGCGCCGTACCCGCCGAGGGCGGCACCCTGCGCATC
CAGCAGGAAGTCCGCGCCCTCAAGGACCCCCGCACCTTTGACTGGTCGCAGATGGCCAACGTCACCCGCGGGTTCCTGGA
ATATCTGATCCAGTACAACAACGACGGCTCGTTCGAGGGCATCCTACTGGAAAGCTGGGAAGCCAATGAGGACGCAACGG
TCTACACGCTGAACGTGCGCCAGGGGATTTCCTGGAACAACGGCGATGCCTTCACGGCCGAAGACGTGGCGGCCAACCTG
ATCGGCTTCTGCGACACAACCGTCGAAGGCAATTCCATGGCCACCCGCATGGGCGGTCTGGTGGACGAAGAGACCGGCCT
GGCCCGCGAGGGCGCGATTGAGGTCGTGGACGATCATACCGTGCGCGTCACCTACCCGTCCCCGGACATCACCTTCGTGC
CCGGCGTGGCGGACTACCCCTCCGCGATCCAGCACCGCGATCTGATCGGCACCAACCCGTCTGATCACGGCGTGGGCACC
GGCGCCTATGAGATCACGTCCTATGAGGTGGGTGTCGCCGCGACGCTCTCGCGCAAGGCCGATCACGAGTATTGGGGCGA
CACATATCTGGATGAAATTGTGTTCGTCGACCTGGGCCAGGATCCCGCCGCCTGGTTTGCGGGCGCGGAAGCCGATGAAT
TCGACATGACCTACGAGACCGTGGGTGAATTCGTGGACCTCTTCGCCGCCATCGGTTGGGATCAGTCCGAAGTTGTGACG
GCGGCCACCGTTGTGGTGCGTCCCAACCAGAACAACGCGCCCTACGACAACCTTCAGGTGCGCCAGGCCATCCAACTGGC
CGTGGACAACCAGGTCTGCCTTGATCTGGGCATCAACGGCCAGGGCGTGACGGCGGAAAACCACCATGTCTGCCCGATCC
ACCCGGAATATGCGGAACTGCCGCCCCTGACCCATGATCCCGCAGCCGCCCAGGCGCTGCTGGAGGAATCGGGCCACGCG
GATACAGAGTTCGAGCTGGTCTCCATCGACGATGATTACCGCAAAAACACCACCGATGCCGTGGCTGCGCAGCTGCGTGA
CGCGGGCTTTAACGTGACGCGGACGATCATCCCCGGCTCGACGTTCTGGAACGACTGGACGTCCTATCCGTTCAGCTCCA
CCAACTGGAACCACCGCGAATTGGGCGTGCAGATCCTCAACCTCGCCTACCGCTCCGGTGTGCCGTGGAACGAGTCAGGC
TTTGCCAATGACGAGTTCGATGCGCTGCTGACCGAGGCCAACGGCATCCAGGACGCCGATGCACGCCGTGAGATCATGGC
GCAGCTGCAAACGATCATGCAGGAGCAGGGCGTGACCATTCAGCCCTACTGGCGCTCGCTCTTCCGGCACTCGCGTCCGG
GTCTCGTGAACAACGAGATGCATGCGAAGTTCGAGATCAACGTGCATTACCTCGGCTTCGCGGCCTAA

Upstream 100 bases:

>100_bases
GTCGACGGTTTGCACGGAGATCTGGCGCAATAAGCCATGCCCGGGCAGACCGAGGGATAACAGAAAACACGATCAAGACG
TCACAGGGAGACGACGACAC

Downstream 100 bases:

>100_bases
GGCTCACACCAACATCCCGGCGCTCCCACCTATGGGTGCGCCGGTTTTTTTCGCGGGATCAGGCAAACGTCGGACCGCAA
CGGCCAAACCCCGCCCTGAC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MKDFTHTTTQVQQQGGLTTHPVAEMYAAEHKAGRLDRREFLVRSTALGLSAAAAYSLIGATPAMADGHRAVPAEGGTLRI
QQEVRALKDPRTFDWSQMANVTRGFLEYLIQYNNDGSFEGILLESWEANEDATVYTLNVRQGISWNNGDAFTAEDVAANL
IGFCDTTVEGNSMATRMGGLVDEETGLAREGAIEVVDDHTVRVTYPSPDITFVPGVADYPSAIQHRDLIGTNPSDHGVGT
GAYEITSYEVGVAATLSRKADHEYWGDTYLDEIVFVDLGQDPAAWFAGAEADEFDMTYETVGEFVDLFAAIGWDQSEVVT
AATVVVRPNQNNAPYDNLQVRQAIQLAVDNQVCLDLGINGQGVTAENHHVCPIHPEYAELPPLTHDPAAAQALLEESGHA
DTEFELVSIDDDYRKNTTDAVAAQLRDAGFNVTRTIIPGSTFWNDWTSYPFSSTNWNHRELGVQILNLAYRSGVPWNESG
FANDEFDALLTEANGIQDADARREIMAQLQTIMQEQGVTIQPYWRSLFRHSRPGLVNNEMHAKFEINVHYLGFAA

Sequences:

>Translated_555_residues
MKDFTHTTTQVQQQGGLTTHPVAEMYAAEHKAGRLDRREFLVRSTALGLSAAAAYSLIGATPAMADGHRAVPAEGGTLRI
QQEVRALKDPRTFDWSQMANVTRGFLEYLIQYNNDGSFEGILLESWEANEDATVYTLNVRQGISWNNGDAFTAEDVAANL
IGFCDTTVEGNSMATRMGGLVDEETGLAREGAIEVVDDHTVRVTYPSPDITFVPGVADYPSAIQHRDLIGTNPSDHGVGT
GAYEITSYEVGVAATLSRKADHEYWGDTYLDEIVFVDLGQDPAAWFAGAEADEFDMTYETVGEFVDLFAAIGWDQSEVVT
AATVVVRPNQNNAPYDNLQVRQAIQLAVDNQVCLDLGINGQGVTAENHHVCPIHPEYAELPPLTHDPAAAQALLEESGHA
DTEFELVSIDDDYRKNTTDAVAAQLRDAGFNVTRTIIPGSTFWNDWTSYPFSSTNWNHRELGVQILNLAYRSGVPWNESG
FANDEFDALLTEANGIQDADARREIMAQLQTIMQEQGVTIQPYWRSLFRHSRPGLVNNEMHAKFEINVHYLGFAA
>Mature_555_residues
MKDFTHTTTQVQQQGGLTTHPVAEMYAAEHKAGRLDRREFLVRSTALGLSAAAAYSLIGATPAMADGHRAVPAEGGTLRI
QQEVRALKDPRTFDWSQMANVTRGFLEYLIQYNNDGSFEGILLESWEANEDATVYTLNVRQGISWNNGDAFTAEDVAANL
IGFCDTTVEGNSMATRMGGLVDEETGLAREGAIEVVDDHTVRVTYPSPDITFVPGVADYPSAIQHRDLIGTNPSDHGVGT
GAYEITSYEVGVAATLSRKADHEYWGDTYLDEIVFVDLGQDPAAWFAGAEADEFDMTYETVGEFVDLFAAIGWDQSEVVT
AATVVVRPNQNNAPYDNLQVRQAIQLAVDNQVCLDLGINGQGVTAENHHVCPIHPEYAELPPLTHDPAAAQALLEESGHA
DTEFELVSIDDDYRKNTTDAVAAQLRDAGFNVTRTIIPGSTFWNDWTSYPFSSTNWNHRELGVQILNLAYRSGVPWNESG
FANDEFDALLTEANGIQDADARREIMAQLQTIMQEQGVTIQPYWRSLFRHSRPGLVNNEMHAKFEINVHYLGFAA

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=480, Percent_Identity=20.625, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789966, Length=301, Percent_Identity=24.9169435215947, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789887, Length=362, Percent_Identity=23.2044198895028, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787052, Length=317, Percent_Identity=24.2902208201893, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61091; Mature: 61091

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFTHTTTQVQQQGGLTTHPVAEMYAAEHKAGRLDRREFLVRSTALGLSAAAAYSLIGA
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHCC
TPAMADGHRAVPAEGGTLRIQQEVRALKDPRTFDWSQMANVTRGFLEYLIQYNNDGSFEG
CCCCCCCCEECCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
ILLESWEANEDATVYTLNVRQGISWNNGDAFTAEDVAANLIGFCDTTVEGNSMATRMGGL
EEEECCCCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHCCC
VDEETGLAREGAIEVVDDHTVRVTYPSPDITFVPGVADYPSAIQHRDLIGTNPSDHGVGT
CCCCCCCCCCCCEEEECCCEEEEEECCCCEEECCCCCCCCHHHHHCCCCCCCCCCCCCCC
GAYEITSYEVGVAATLSRKADHEYWGDTYLDEIVFVDLGQDPAAWFAGAEADEFDMTYET
CEEEEEEEECCEEEEHHHCCCCCCCCCHHHCCEEEEECCCCHHHHHCCCCCCCCCCHHHH
VGEFVDLFAAIGWDQSEVVTAATVVVRPNQNNAPYDNLQVRQAIQLAVDNQVCLDLGING
HHHHHHHHHHCCCCCHHEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCC
QGVTAENHHVCPIHPEYAELPPLTHDPAAAQALLEESGHADTEFELVSIDDDYRKNTTDA
CCCCCCCCEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHH
VAAQLRDAGFNVTRTIIPGSTFWNDWTSYPFSSTNWNHRELGVQILNLAYRSGVPWNESG
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
FANDEFDALLTEANGIQDADARREIMAQLQTIMQEQGVTIQPYWRSLFRHSRPGLVNNEM
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHCCCCCCCCCCC
HAKFEINVHYLGFAA
EEEEEEEEEEEEEEC
>Mature Secondary Structure
MKDFTHTTTQVQQQGGLTTHPVAEMYAAEHKAGRLDRREFLVRSTALGLSAAAAYSLIGA
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHCC
TPAMADGHRAVPAEGGTLRIQQEVRALKDPRTFDWSQMANVTRGFLEYLIQYNNDGSFEG
CCCCCCCCEECCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
ILLESWEANEDATVYTLNVRQGISWNNGDAFTAEDVAANLIGFCDTTVEGNSMATRMGGL
EEEECCCCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHCCC
VDEETGLAREGAIEVVDDHTVRVTYPSPDITFVPGVADYPSAIQHRDLIGTNPSDHGVGT
CCCCCCCCCCCCEEEECCCEEEEEECCCCEEECCCCCCCCHHHHHCCCCCCCCCCCCCCC
GAYEITSYEVGVAATLSRKADHEYWGDTYLDEIVFVDLGQDPAAWFAGAEADEFDMTYET
CEEEEEEEECCEEEEHHHCCCCCCCCCHHHCCEEEEECCCCHHHHHCCCCCCCCCCHHHH
VGEFVDLFAAIGWDQSEVVTAATVVVRPNQNNAPYDNLQVRQAIQLAVDNQVCLDLGING
HHHHHHHHHHCCCCCHHEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCC
QGVTAENHHVCPIHPEYAELPPLTHDPAAAQALLEESGHADTEFELVSIDDDYRKNTTDA
CCCCCCCCEECCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHH
VAAQLRDAGFNVTRTIIPGSTFWNDWTSYPFSSTNWNHRELGVQILNLAYRSGVPWNESG
HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
FANDEFDALLTEANGIQDADARREIMAQLQTIMQEQGVTIQPYWRSLFRHSRPGLVNNEM
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHCCCCCCCCCCC
HAKFEINVHYLGFAA
EEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]