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The map label for this gene is fabZ

Identifier: 89054942

GI number: 89054942

Start: 2443574

End: 2444059

Strand: Reverse

Name: fabZ

Synonym: Jann_2451

Alternate gene names: 89054942

Gene position: 2444059-2443574 (Counterclockwise)

Preceding gene: 89054943

Following gene: 89054941

Centisome position: 56.6

GC content: 62.96

Gene sequence:

>486_bases
ATGACGGCAGACACGCCCACGACCGCCGACATTGACCTGATCCAGCGGATCCTGCCGCACCGCTATCCGTTTCTGCTGGT
GGACCGTGTGCGCGATATCGAGCCGTTCAAATCTGCCGTGGGCCTCAAGAACGTCACCGTGAACGAGCCGCATTTCCAAG
GCCATTTCCCTGGCGTTCCGATCATGCCCGGCGTCACGATTGTCGAGGCGATGGCCCAGACCGCCGCCGTGATGGTGGGC
GTCTCTGCCGATCTGGCCGACAAGAATTTCCTCGTCTATTTCATGGGGATCGACAGCTGCAAGTTCCGCCGCAAAGTGGG
CCCCGGTGACGTGCTGGAGCTGCATGTGACTGCCACGCGCGGCAAGCCCGGTGCCAAGGTCTGGAAGTTCGATGGTCGTG
CGGAGGTCGATGGAGAGCTGGCCTGCGAATGCTCCTTCACCGCGATGATGGACCTTCCGACGTCCCCCCCCGGGGAGGCT
GGGTGA

Upstream 100 bases:

>100_bases
TGCCCGGCCTGTCCCCACCGGAGTAGACCTGCCGCCGCTGCCTTGCCGTGACCCGGCTGAGTTGCTAGGCGTCATCCACC
ATAACTTTCGGAGATCAGCC

Downstream 100 bases:

>100_bases
ATGGCGATCCACGCCTCCGCCCAGATCCACCCCTCCGCCGTGATCGAGGAGGGGGCCGTGATCGGCGCGAACTGCCAGAT
CGGCCCGTTCTGCCTTGTCG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTADTPTTADIDLIQRILPHRYPFLLVDRVRDIEPFKSAVGLKNVTVNEPHFQGHFPGVPIMPGVTIVEAMAQTAAVMVG
VSADLADKNFLVYFMGIDSCKFRRKVGPGDVLELHVTATRGKPGAKVWKFDGRAEVDGELACECSFTAMMDLPTSPPGEA
G

Sequences:

>Translated_161_residues
MTADTPTTADIDLIQRILPHRYPFLLVDRVRDIEPFKSAVGLKNVTVNEPHFQGHFPGVPIMPGVTIVEAMAQTAAVMVG
VSADLADKNFLVYFMGIDSCKFRRKVGPGDVLELHVTATRGKPGAKVWKFDGRAEVDGELACECSFTAMMDLPTSPPGEA
G
>Mature_160_residues
TADTPTTADIDLIQRILPHRYPFLLVDRVRDIEPFKSAVGLKNVTVNEPHFQGHFPGVPIMPGVTIVEAMAQTAAVMVGV
SADLADKNFLVYFMGIDSCKFRRKVGPGDVLELHVTATRGKPGAKVWKFDGRAEVDGELACECSFTAMMDLPTSPPGEAG

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=145, Percent_Identity=47.5862068965517, Blast_Score=130, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_JANSC (Q28PJ4)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510393.1
- ProteinModelPortal:   Q28PJ4
- SMR:   Q28PJ4
- STRING:   Q28PJ4
- GeneID:   3934908
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2451
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KNIRADY
- PhylomeDB:   Q28PJ4
- ProtClustDB:   PRK00006
- BioCyc:   JSP290400:JANN_2451-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17444; Mature: 17313

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: ACT_SITE 55-55

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADTPTTADIDLIQRILPHRYPFLLVDRVRDIEPFKSAVGLKNVTVNEPHFQGHFPGVP
CCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHCCCHHHHHCCCCCEECCCCCCCCCCCCCC
IMPGVTIVEAMAQTAAVMVGVSADLADKNFLVYFMGIDSCKFRRKVGPGDVLELHVTATR
CCCCHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCHHCCCCCCCEEEEEEEEEC
GKPGAKVWKFDGRAEVDGELACECSFTAMMDLPTSPPGEAG
CCCCCEEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TADTPTTADIDLIQRILPHRYPFLLVDRVRDIEPFKSAVGLKNVTVNEPHFQGHFPGVP
CCCCCCCCCHHHHHHHHCCCCCEEEEHHHHCCCHHHHHCCCCCEECCCCCCCCCCCCCC
IMPGVTIVEAMAQTAAVMVGVSADLADKNFLVYFMGIDSCKFRRKVGPGDVLELHVTATR
CCCCHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCCCHHCCCCCCCEEEEEEEEEC
GKPGAKVWKFDGRAEVDGELACECSFTAMMDLPTSPPGEAG
CCCCCEEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA