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The map label for this gene is ctaA

Identifier: 89054923

GI number: 89054923

Start: 2426011

End: 2427150

Strand: Reverse

Name: ctaA

Synonym: Jann_2432

Alternate gene names: 89054923

Gene position: 2427150-2426011 (Counterclockwise)

Preceding gene: 89054924

Following gene: 89054922

Centisome position: 56.21

GC content: 64.74

Gene sequence:

>1140_bases
ATGGCCGGATCGCGCAGTATTTTTGAAGAGGTCCAGGACAGCCAGAAACCGGCCGCGATGCCCGGCGGTGTCAGCCGGGA
TCGGGGGCGCGGACGGGCGCGGGTGCGTGTTTTCATCATGATCCTGTTTGTGATGGTGGTTGTGCAGATCGCCATTGGGG
GCCTGACGCGCCTGACGGATTCGGGGCTGTCGATCACCGAATGGGCGCCGATTACCGGGGCGATCCCACCGTTGGACGAG
GCGGCGTGGGAGGCCGAGTTGGAGGCCTACCGGGCCACGACGGAGTATCAGGAACAGAACCGGGGCATGAGCCTGGCCGA
GTTCAAGGTCATCTACTGGTGGGAATGGGGCCATCGCCAATGGGCGCGGTTCCTCGGCGTCGTCTGGGCCGTGGGCTTTG
TGGGGCTACTGGCCACGAAGTCGGTGCCCGTTGGCTGGACCGGTCGTCTGTTGCTGTTGGGCGTTTTGGGCGGGCTTCAG
GGCGTGGCCGGGTGGTGGATGGTCCATTCCGGCCTCGCGCCGGGGATGTTTGATGTGGCCTCCTACCGACTTGCCGTCCA
TCTGGGGCTCGCCTTCCTGATCCTGGGGCTGATGGCGTGGTACATTCTGCGCCTGGGTCGGGCGGAGGCGGAGTTGATGA
CCGCGCGCCGCGATGGCGACCGGATGCTGGCGGGCATGGCGACGGGGCTCTTGCATCTGACGGCGCTGCAAATTCTGATC
GGCGCGCTGGTGGCGGGCATCGACGCGGGCCGCAATTACATTGACTGGCCGCTGATGGCGGGCGCGTTCACGCCGCCGGA
TATGTGGGCGATAGAGCCTTGGTATCGCAACCTCTTTGAGAATGACGGGACGGTGCAGTTTTTCCACCGCGTAACGGGGT
ATCTGCTGTTTGTAATCGGCGTTGCTGCCTGGATCATGGCGCGCCGGTCCGCCCGCACGGCGACCAAACGGGCCTTCGAC
TGGATGGCCGTGATGCTGTTCGGCCAGATCGTGCTGGGGATTATGACTGTCATGCACTCCTCGCCATGGTATCTGGCGAT
TGTGCACCAGTTCGGGGCCGTGGTCCTGATCACCCTGATCCTGCGCGCGCGCTTCCTGGCGCGCTATCCGCTTCCCCAAT
CCGTGAGAGGAGCCGCCTGA

Upstream 100 bases:

>100_bases
AGTGCACCACTGGGTTGAGCGCGCGAGAGAGTGTCGCGGGCGCTTGAAGGGCGCGGGGTCGCGCGATAGGTCACGAGGGG
AGAGATAAGAGGATCGAGCC

Downstream 100 bases:

>100_bases
TGGCCGCTTTGGACGATCTGCTGACCTACAACCGCAAGACCGAGGCTTTGGGCCAGGTCATGGGCCGCCTGGGGTGGGAC
CAGGAAACGATGATGCCACC

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MAGSRSIFEEVQDSQKPAAMPGGVSRDRGRGRARVRVFIMILFVMVVVQIAIGGLTRLTDSGLSITEWAPITGAIPPLDE
AAWEAELEAYRATTEYQEQNRGMSLAEFKVIYWWEWGHRQWARFLGVVWAVGFVGLLATKSVPVGWTGRLLLLGVLGGLQ
GVAGWWMVHSGLAPGMFDVASYRLAVHLGLAFLILGLMAWYILRLGRAEAELMTARRDGDRMLAGMATGLLHLTALQILI
GALVAGIDAGRNYIDWPLMAGAFTPPDMWAIEPWYRNLFENDGTVQFFHRVTGYLLFVIGVAAWIMARRSARTATKRAFD
WMAVMLFGQIVLGIMTVMHSSPWYLAIVHQFGAVVLITLILRARFLARYPLPQSVRGAA

Sequences:

>Translated_379_residues
MAGSRSIFEEVQDSQKPAAMPGGVSRDRGRGRARVRVFIMILFVMVVVQIAIGGLTRLTDSGLSITEWAPITGAIPPLDE
AAWEAELEAYRATTEYQEQNRGMSLAEFKVIYWWEWGHRQWARFLGVVWAVGFVGLLATKSVPVGWTGRLLLLGVLGGLQ
GVAGWWMVHSGLAPGMFDVASYRLAVHLGLAFLILGLMAWYILRLGRAEAELMTARRDGDRMLAGMATGLLHLTALQILI
GALVAGIDAGRNYIDWPLMAGAFTPPDMWAIEPWYRNLFENDGTVQFFHRVTGYLLFVIGVAAWIMARRSARTATKRAFD
WMAVMLFGQIVLGIMTVMHSSPWYLAIVHQFGAVVLITLILRARFLARYPLPQSVRGAA
>Mature_378_residues
AGSRSIFEEVQDSQKPAAMPGGVSRDRGRGRARVRVFIMILFVMVVVQIAIGGLTRLTDSGLSITEWAPITGAIPPLDEA
AWEAELEAYRATTEYQEQNRGMSLAEFKVIYWWEWGHRQWARFLGVVWAVGFVGLLATKSVPVGWTGRLLLLGVLGGLQG
VAGWWMVHSGLAPGMFDVASYRLAVHLGLAFLILGLMAWYILRLGRAEAELMTARRDGDRMLAGMATGLLHLTALQILIG
ALVAGIDAGRNYIDWPLMAGAFTPPDMWAIEPWYRNLFENDGTVQFFHRVTGYLLFVIGVAAWIMARRSARTATKRAFDW
MAVMLFGQIVLGIMTVMHSSPWYLAIVHQFGAVVLITLILRARFLARYPLPQSVRGAA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=316, Percent_Identity=36.0759493670886, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI17921987, Length=266, Percent_Identity=36.8421052631579, Blast_Score=151, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17536069, Length=340, Percent_Identity=34.7058823529412, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320989, Length=340, Percent_Identity=35.5882352941176, Blast_Score=177, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19922860, Length=337, Percent_Identity=36.2017804154303, Blast_Score=178, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_JANSC (Q28PL3)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510374.1
- STRING:   Q28PL3
- GeneID:   3934889
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2432
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q28PL3
- ProtClustDB:   CLSK2767268
- BioCyc:   JSP290400:JANN_2432-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 42038; Mature: 41907

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: BINDING 349-349

Signals:

None

Transmembrane regions:

HASH(0x113bf5ac)-; HASH(0x1143ce70)-; HASH(0xe0b00a0)-; HASH(0xb46aa98)-; HASH(0x10bcbcec)-; HASH(0x10d1fff4)-; HASH(0x10dc3654)-; HASH(0x10e21dbc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSRSIFEEVQDSQKPAAMPGGVSRDRGRGRARVRVFIMILFVMVVVQIAIGGLTRLTD
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
SGLSITEWAPITGAIPPLDEAAWEAELEAYRATTEYQEQNRGMSLAEFKVIYWWEWGHRQ
CCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHEEEEEEEECCHHH
WARFLGVVWAVGFVGLLATKSVPVGWTGRLLLLGVLGGLQGVAGWWMVHSGLAPGMFDVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
SYRLAVHLGLAFLILGLMAWYILRLGRAEAELMTARRDGDRMLAGMATGLLHLTALQILI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GALVAGIDAGRNYIDWPLMAGAFTPPDMWAIEPWYRNLFENDGTVQFFHRVTGYLLFVIG
HHHHHHHHCCCCCCCCCHHCCCCCCCCCCEECHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VAAWIMARRSARTATKRAFDWMAVMLFGQIVLGIMTVMHSSPWYLAIVHQFGAVVLITLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LRARFLARYPLPQSVRGAA
HHHHHHHHCCCCCCCCCCH
>Mature Secondary Structure 
AGSRSIFEEVQDSQKPAAMPGGVSRDRGRGRARVRVFIMILFVMVVVQIAIGGLTRLTD
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
SGLSITEWAPITGAIPPLDEAAWEAELEAYRATTEYQEQNRGMSLAEFKVIYWWEWGHRQ
CCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHEEEEEEEECCHHH
WARFLGVVWAVGFVGLLATKSVPVGWTGRLLLLGVLGGLQGVAGWWMVHSGLAPGMFDVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
SYRLAVHLGLAFLILGLMAWYILRLGRAEAELMTARRDGDRMLAGMATGLLHLTALQILI
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GALVAGIDAGRNYIDWPLMAGAFTPPDMWAIEPWYRNLFENDGTVQFFHRVTGYLLFVIG
HHHHHHHHCCCCCCCCCHHCCCCCCCCCCEECHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VAAWIMARRSARTATKRAFDWMAVMLFGQIVLGIMTVMHSSPWYLAIVHQFGAVVLITLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LRARFLARYPLPQSVRGAA
HHHHHHHHCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA