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The map label for this gene is grp [H]

Identifier: 89054868

GI number: 89054868

Start: 2381463

End: 2381879

Strand: Direct

Name: grp [H]

Synonym: Jann_2377

Alternate gene names: 89054868

Gene position: 2381463-2381879 (Clockwise)

Preceding gene: 89054865

Following gene: 89054871

Centisome position: 55.15

GC content: 63.31

Gene sequence:

>417_bases
TTGCAACGCCGCTGTGATGAGCCGTTGGAGGAGCTTGGCCACCACGTCGGCCTGTCGCGCAATGCGGTGTGGCGGCGGGT
GAAGGCGTTGGAAGAGCGCGGGGTGCTGACAGGTCGTGTGGCCGTCGTGGATCCTGTGGCCGTGGGTCTTGGCCTGATGG
TGTTCATTCAAGTCCGCGCGGCGCATCATTCGGCGGATTGGCTGGAGCAGTTTCGCCGTGCCGTTCGCGCGATGCCGGAG
ATTTTGGGCGTTTACCGCATGACCGGCGATCTGGATTACTTGATCCGCGCCCGTGTGGCCGATGTGGCGGATTACGACCG
GCTCTATCAGCGGCTCATTGATCGGGTCGAAATGGGCGACGTCTCGGCCAGTTTCGTGATGGAGGAGTTGAAGGAGGGCA
GCGCGCTGCCCCTGTGA

Upstream 100 bases:

>100_bases
CCCAAATATAGCGCTGTTTGGCCGTGACATGTGGAAGACTTCCCACCATATTGCTGTCATGACAAATCTTGACCCAACAG
ACGCCCGTATCCTCGCCCAT

Downstream 100 bases:

>100_bases
TTTCGTCGCGCGGGTATATCAATCGTATATCAATTGCCGACATGGGGTCCCAGCACAGGGTCCCAGAGCGCGGGGTAGAT
CAATGGTAGATCAATTTGCC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MQRRCDEPLEELGHHVGLSRNAVWRRVKALEERGVLTGRVAVVDPVAVGLGLMVFIQVRAAHHSADWLEQFRRAVRAMPE
ILGVYRMTGDLDYLIRARVADVADYDRLYQRLIDRVEMGDVSASFVMEELKEGSALPL

Sequences:

>Translated_138_residues
MQRRCDEPLEELGHHVGLSRNAVWRRVKALEERGVLTGRVAVVDPVAVGLGLMVFIQVRAAHHSADWLEQFRRAVRAMPE
ILGVYRMTGDLDYLIRARVADVADYDRLYQRLIDRVEMGDVSASFVMEELKEGSALPL
>Mature_138_residues
MQRRCDEPLEELGHHVGLSRNAVWRRVKALEERGVLTGRVAVVDPVAVGLGLMVFIQVRAAHHSADWLEQFRRAVRAMPE
ILGVYRMTGDLDYLIRARVADVADYDRLYQRLIDRVEMGDVSASFVMEELKEGSALPL

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=139, Percent_Identity=42.4460431654676, Blast_Score=137, Evalue=2e-34,
Organism=Escherichia coli, GI1787116, Length=127, Percent_Identity=33.8582677165354, Blast_Score=80, Evalue=5e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 15672; Mature: 15672

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRRCDEPLEELGHHVGLSRNAVWRRVKALEERGVLTGRVAVVDPVAVGLGLMVFIQVRA
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AHHSADWLEQFRRAVRAMPEILGVYRMTGDLDYLIRARVADVADYDRLYQRLIDRVEMGD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VSASFVMEELKEGSALPL
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRRCDEPLEELGHHVGLSRNAVWRRVKALEERGVLTGRVAVVDPVAVGLGLMVFIQVRA
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AHHSADWLEQFRRAVRAMPEILGVYRMTGDLDYLIRARVADVADYDRLYQRLIDRVEMGD
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VSASFVMEELKEGSALPL
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]