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The map label for this gene is fabG3 [H]

Identifier: 89054865

GI number: 89054865

Start: 2379387

End: 2380142

Strand: Direct

Name: fabG3 [H]

Synonym: Jann_2374

Alternate gene names: 89054865

Gene position: 2379387-2380142 (Clockwise)

Preceding gene: 89054864

Following gene: 89054868

Centisome position: 55.1

GC content: 65.21

Gene sequence:

>756_bases
ATGACCCAACCGCAATTCGCCCGCTACCCCTCCCTCGACGGCGCGTCCGTGTTCATCACCGGCGGCGCATCTGGCATCGG
TGCGGGCATGGTGCGGGCTTTCGCCGATCAGGGTGCTCAGGTGGGGTTCGTGGATATGGATGCGGACGGCGGCACCGCGC
TGGCATCTGAAACCGGCGCGACCTTCGCCGCCTGTGATCTGCGCGATATCAACGGGTTACGCAGCGCGTTCGCCACACTG
GCCGACGCCAATGGCCCGGCGCAAGTGCTGGTCAACAATGCCGCCCGCGATGACCGGCATAATTGGAAAGACGTCACGCC
GGAATATTGGGACGACCGTCAGAACACCAACCTGCGCCACCAGTTCTTCGCGATTCAGGCCGTGGCCCCTGCGATGATCG
CGGCGGGCAAGGGCTCCATCATCAACATGGGCTCCAATTCCTGGTGGGAGGCGGGCGGCGGTTTCCCGGCCTACGCCACC
GCCAAATCCGCCGCCCATGGGCTGACCCGCACCATGGCCCGCGACCTTGGCCCCCACCGCATCCGCGTGAACACGATTGT
GCCAGGCTGGATCATGACCGACCGCCAAAGGGAGCTGTGGGTGACGGAAGAGGCCCTGGACGCCCAACTCAAGCGCCAGT
GCCTGCCAGACCCCATCGACCCGGTCTACGTCGTGCGCATGGCGCTGTTTCTGGCCTCCGACGACGCGGCGATGTGTTCG
GCCAACAATTACATGGTGGAAGCGGGCTCGATCTGA

Upstream 100 bases:

>100_bases
TTCTTTGCACGCCGCGTTTCAGGCGGTGGGTCAAATTGTAGGCCCATTGACCTCTGCCGCGCGTCACCGCACCCTGCCCC
GACCCATGACGGAGCGCCCT

Downstream 100 bases:

>100_bases
CGATGCTATGACAAGTATCGTGCGGAGCCCAAGTCGCGGATGACGGGCTGATCTGACGCGCAAGACGCGACGCCGCATCT
CTGACGTCTGGGCGGGCTGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTQPQFARYPSLDGASVFITGGASGIGAGMVRAFADQGAQVGFVDMDADGGTALASETGATFAACDLRDINGLRSAFATL
ADANGPAQVLVNNAARDDRHNWKDVTPEYWDDRQNTNLRHQFFAIQAVAPAMIAAGKGSIINMGSNSWWEAGGGFPAYAT
AKSAAHGLTRTMARDLGPHRIRVNTIVPGWIMTDRQRELWVTEEALDAQLKRQCLPDPIDPVYVVRMALFLASDDAAMCS
ANNYMVEAGSI

Sequences:

>Translated_251_residues
MTQPQFARYPSLDGASVFITGGASGIGAGMVRAFADQGAQVGFVDMDADGGTALASETGATFAACDLRDINGLRSAFATL
ADANGPAQVLVNNAARDDRHNWKDVTPEYWDDRQNTNLRHQFFAIQAVAPAMIAAGKGSIINMGSNSWWEAGGGFPAYAT
AKSAAHGLTRTMARDLGPHRIRVNTIVPGWIMTDRQRELWVTEEALDAQLKRQCLPDPIDPVYVVRMALFLASDDAAMCS
ANNYMVEAGSI
>Mature_250_residues
TQPQFARYPSLDGASVFITGGASGIGAGMVRAFADQGAQVGFVDMDADGGTALASETGATFAACDLRDINGLRSAFATLA
DANGPAQVLVNNAARDDRHNWKDVTPEYWDDRQNTNLRHQFFAIQAVAPAMIAAGKGSIINMGSNSWWEAGGGFPAYATA
KSAAHGLTRTMARDLGPHRIRVNTIVPGWIMTDRQRELWVTEEALDAQLKRQCLPDPIDPVYVVRMALFLASDDAAMCSA
NNYMVEAGSI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=240, Percent_Identity=33.75, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=29.3436293436293, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=29.6153846153846, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723750, Length=146, Percent_Identity=34.2465753424658, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI66933014, Length=243, Percent_Identity=28.8065843621399, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=213, Percent_Identity=25.8215962441315, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI4758504, Length=197, Percent_Identity=32.994923857868, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=27.4336283185841, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=192, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=27.0833333333333, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1789208, Length=198, Percent_Identity=32.8282828282828, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=30.2788844621514, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=29.3388429752066, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=32.9268292682927, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=30.2904564315353, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082160, Length=190, Percent_Identity=29.4736842105263, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788891, Length=228, Percent_Identity=32.0175438596491, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=25.4032258064516, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788459, Length=183, Percent_Identity=31.1475409836066, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=236, Percent_Identity=27.9661016949153, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=189, Percent_Identity=27.5132275132275, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=236, Percent_Identity=27.9661016949153, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=243, Percent_Identity=27.9835390946502, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=246, Percent_Identity=28.0487804878049, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=162, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=26.1224489795918, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=25.6809338521401, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=241, Percent_Identity=28.2157676348548, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=235, Percent_Identity=29.3617021276596, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=29.4605809128631, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=28.4552845528455, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=31.2252964426877, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=29.8804780876494, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639444, Length=229, Percent_Identity=29.2576419213974, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=25.7261410788382, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=26.4227642276423, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355319, Length=231, Percent_Identity=25.1082251082251, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.53 [H]

Molecular weight: Translated: 26886; Mature: 26755

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPQFARYPSLDGASVFITGGASGIGAGMVRAFADQGAQVGFVDMDADGGTALASETGA
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
TFAACDLRDINGLRSAFATLADANGPAQVLVNNAARDDRHNWKDVTPEYWDDRQNTNLRH
EEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCHHH
QFFAIQAVAPAMIAAGKGSIINMGSNSWWEAGGGFPAYATAKSAAHGLTRTMARDLGPHR
HHEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
IRVNTIVPGWIMTDRQRELWVTEEALDAQLKRQCLPDPIDPVYVVRMALFLASDDAAMCS
EEEEEECCCEEECCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEEC
ANNYMVEAGSI
CCCEEEEECCC
>Mature Secondary Structure 
TQPQFARYPSLDGASVFITGGASGIGAGMVRAFADQGAQVGFVDMDADGGTALASETGA
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
TFAACDLRDINGLRSAFATLADANGPAQVLVNNAARDDRHNWKDVTPEYWDDRQNTNLRH
EEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCHHH
QFFAIQAVAPAMIAAGKGSIINMGSNSWWEAGGGFPAYATAKSAAHGLTRTMARDLGPHR
HHEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
IRVNTIVPGWIMTDRQRELWVTEEALDAQLKRQCLPDPIDPVYVVRMALFLASDDAAMCS
EEEEEECCCEEECCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHEEC
ANNYMVEAGSI
CCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]