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The map label for this gene is sufC [H]

Identifier: 89054850

GI number: 89054850

Start: 2364640

End: 2365395

Strand: Reverse

Name: sufC [H]

Synonym: Jann_2359

Alternate gene names: 89054850

Gene position: 2365395-2364640 (Counterclockwise)

Preceding gene: 89054851

Following gene: 89054849

Centisome position: 54.78

GC content: 60.32

Gene sequence:

>756_bases
ATGTTGGATATCAAAGGCCTGGCCGTAAAACTTGAAGAAGAAGATAAGCAGATCCTCAAAGGCGTGGATCTGTCCGTGGA
CGCGGGCAAGGTGCACGCGATCATGGGGCCTAACGGGTCCGGCAAGTCCACGCTGTCCTATGTTCTTTCGGGCAAGGGCG
GCTACGAGGTGACGGCGGGTGAGGCCACTCTGGACGGTGAAGACCTGCTGGATATGGACCCCGAAGAGCGCGCGGCGGCG
GGCCTGTTCCTGGCGTTCCAATACCCCGTTGAAATCCCCGGCGTGGGCAACATGACCTTCCTGCGCACCGCCGTGAACGC
CCAACGCAAGCTGCGCGGCGAAGAGGAGATGTCGGCGGGCGAGTTCCTGAAGGTGATCCGCGCCAAAGCCAAAGACCTGA
AGATTGACGCAGAGATGCTGAAGCGGCCTGTGAATGTGGGCTTTTCGGGCGGTGAGAAGAAGCGCAATGAAATCCTGCAA
ATGGCGATGCTGGAGCCCAAGATGTGCATCCTGGACGAGACCGACTCAGGCCTCGACGTGGATGCCATGAAGCTGGTGTC
GGAGGGGGTGAATGCGCTGCGCGATGCCGGTCGCGGGTTCCTGGTGATCACGCATTATCAGCGTCTGCTGGACCACATCC
AGCCCGACGTCGTGCATATCATGGCTGACGGGCGCATCGTGAAGACGGGCGGGCCGGAACTGGCCCTTGAGGTCGAGAAA
AACGGTTATGCCGATATCCTCTCGGAGGTGGCGTAA

Upstream 100 bases:

>100_bases
TGGGTCGACACCCATGGCTACACGACCCATGAAACCTTCAAACGCTACCGCGACAACGAGAATTTCCTGTTTGTCCCCGA
ATCTGAGAGTGAGACATAAA

Downstream 100 bases:

>100_bases
CCATGGCCGCTCCTGCCGCAAAGCCTGACCTGACCGAGGCGCGCCTTGCCGCGCTGTCGATGCCCGATGGCGCGCCGGAG
GCCCGAAAGGCCGCGCTGGC

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLDIKGLAVKLEEEDKQILKGVDLSVDAGKVHAIMGPNGSGKSTLSYVLSGKGGYEVTAGEATLDGEDLLDMDPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKLRGEEEMSAGEFLKVIRAKAKDLKIDAEMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVSEGVNALRDAGRGFLVITHYQRLLDHIQPDVVHIMADGRIVKTGGPELALEVEK
NGYADILSEVA

Sequences:

>Translated_251_residues
MLDIKGLAVKLEEEDKQILKGVDLSVDAGKVHAIMGPNGSGKSTLSYVLSGKGGYEVTAGEATLDGEDLLDMDPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKLRGEEEMSAGEFLKVIRAKAKDLKIDAEMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVSEGVNALRDAGRGFLVITHYQRLLDHIQPDVVHIMADGRIVKTGGPELALEVEK
NGYADILSEVA
>Mature_251_residues
MLDIKGLAVKLEEEDKQILKGVDLSVDAGKVHAIMGPNGSGKSTLSYVLSGKGGYEVTAGEATLDGEDLLDMDPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKLRGEEEMSAGEFLKVIRAKAKDLKIDAEMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVSEGVNALRDAGRGFLVITHYQRLLDHIQPDVVHIMADGRIVKTGGPELALEVEK
NGYADILSEVA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=239, Percent_Identity=29.2887029288703, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI42741659, Length=222, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9961252, Length=239, Percent_Identity=29.2887029288703, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4505771, Length=239, Percent_Identity=29.2887029288703, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787972, Length=243, Percent_Identity=58.0246913580247, Blast_Score=293, Evalue=6e-81,
Organism=Escherichia coli, GI1787370, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787029, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790525, Length=220, Percent_Identity=30.4545454545455, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789891, Length=243, Percent_Identity=29.6296296296296, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789593, Length=226, Percent_Identity=26.1061946902655, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789962, Length=241, Percent_Identity=27.8008298755187, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789672, Length=222, Percent_Identity=26.5765765765766, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788210, Length=211, Percent_Identity=27.9620853080569, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787500, Length=247, Percent_Identity=28.7449392712551, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=222, Percent_Identity=27.9279279279279, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193211015, Length=222, Percent_Identity=27.4774774774775, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115533592, Length=226, Percent_Identity=27.8761061946903, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=234, Percent_Identity=30.3418803418803, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193211017, Length=222, Percent_Identity=27.9279279279279, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71992290, Length=238, Percent_Identity=28.1512605042017, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=236, Percent_Identity=28.8135593220339, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=228, Percent_Identity=28.5087719298246, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=222, Percent_Identity=26.1261261261261, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27156; Mature: 27156

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIKGLAVKLEEEDKQILKGVDLSVDAGKVHAIMGPNGSGKSTLSYVLSGKGGYEVTAG
CCCCCCEEEEECHHHHHHHCCCCCEECCCEEEEEECCCCCCCCEEEEEEECCCCEEEECC
EATLDGEDLLDMDPEERAAAGLFLAFQYPVEIPGVGNMTFLRTAVNAQRKLRGEEEMSAG
CEEECCCCCCCCCCHHHHHHEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHCCHH
EFLKVIRAKAKDLKIDAEMLKRPVNVGFSGGEKKRNEILQMAMLEPKMCILDETDSGLDV
HHHHHHHHHHHCCEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMKLVSEGVNALRDAGRGFLVITHYQRLLDHIQPDVVHIMADGRIVKTGGPELALEVEK
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEECC
NGYADILSEVA
CCHHHHHHHCC
>Mature Secondary Structure
MLDIKGLAVKLEEEDKQILKGVDLSVDAGKVHAIMGPNGSGKSTLSYVLSGKGGYEVTAG
CCCCCCEEEEECHHHHHHHCCCCCEECCCEEEEEECCCCCCCCEEEEEEECCCCEEEECC
EATLDGEDLLDMDPEERAAAGLFLAFQYPVEIPGVGNMTFLRTAVNAQRKLRGEEEMSAG
CEEECCCCCCCCCCHHHHHHEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHCCHH
EFLKVIRAKAKDLKIDAEMLKRPVNVGFSGGEKKRNEILQMAMLEPKMCILDETDSGLDV
HHHHHHHHHHHCCEECHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMKLVSEGVNALRDAGRGFLVITHYQRLLDHIQPDVVHIMADGRIVKTGGPELALEVEK
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEECC
NGYADILSEVA
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]