BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

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The map label for this gene is bdhA [H]

Identifier: 89054802

GI number: 89054802

Start: 2315961

End: 2316746

Strand: Direct

Name: bdhA [H]

Synonym: Jann_2311

Alternate gene names: 89054802

Gene position: 2315961-2316746 (Clockwise)

Preceding gene: 89054800

Following gene: 89054803

Centisome position: 53.64

GC content: 61.45

Gene sequence:

>786_bases
ATGGCCATCACCACTGACTTGTCCGGCAAGACCGCCGTGATCACCGGATCGAACTCGGGAATCGGGTTGGGGGTTGCGCG
GGAACTGGCCCGCGCCGGCGCGAATGTCGTTCTGAATTCCTATACTGACACCAAGAAAGACCATGCGTTGGCCGAAGAGA
TCGCCGCCAACTTCAGCGTCGATGCCCGCTATATTCAGGCGGACCTGTCCAAGGGCGATCAGGCCCGGGGTCTGATCGAG
GAGGCGGGCGTCTGCGATATCCTGATCAACAATGCAGGCATCCAGCACGTCGCCCCCATAGATGAGTTTCCGGTGGAGAA
ATGGGATGCGATCATTGCGATCATGCTGTCCTCGGCCTTCCACACCACGGCCGTGGCTCTGCCGATGATGCGCGACGCCG
GCTGGGGCCGGGTCATCAACATCTCCAGCGCCCATGGCTTGACCGCGTCGCCCTACAAATCGGCCTATGTGTCGGCCAAG
CACGGCGTTGTCGGCATGACCAAGGTTGTCGCCCTTGAGACCGCGAAAGAGCCCATCACCGCCAATGCCATCTGCCCAGG
CTACGTTCTGACCCCGCTGGTGGAGAGCCAGATCCCCGACACGGCGAAGAAATACGACATGTCGGAGGAGGAGGTGAAGC
AGAAGGTCATCCTGGAGCGCCAACCCTCCAAGGAATTCGCCACGACCGAGCAGTTGGGCGGCACCGTCGCCTTCCTCTGC
TCTGCCGCCGCCGATCAGATCACTGGCACCACCATCAGCGTTGACGGAGGATGGACAGCGTTGTGA

Upstream 100 bases:

>100_bases
GCTTTTGCAAAAGCCTTCCGCCGTTGACCCAAGGCGCCCCCTGTTCATTTCGCACCCGCAGCATTAGCGTGGCGAAAACG
ACCTATTCAGGAGCATCCCC

Downstream 100 bases:

>100_bases
TCCGCAGAAGGCGGATCACAACGGGCCGGAAAAGGCGGTTTTGCCAAAGCAAAACCTGCCGACCGGCACCCTAACCATTC
CAGGCGCACTACACCCCACG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAITTDLSGKTAVITGSNSGIGLGVARELARAGANVVLNSYTDTKKDHALAEEIAANFSVDARYIQADLSKGDQARGLIE
EAGVCDILINNAGIQHVAPIDEFPVEKWDAIIAIMLSSAFHTTAVALPMMRDAGWGRVINISSAHGLTASPYKSAYVSAK
HGVVGMTKVVALETAKEPITANAICPGYVLTPLVESQIPDTAKKYDMSEEEVKQKVILERQPSKEFATTEQLGGTVAFLC
SAAADQITGTTISVDGGWTAL

Sequences:

>Translated_261_residues
MAITTDLSGKTAVITGSNSGIGLGVARELARAGANVVLNSYTDTKKDHALAEEIAANFSVDARYIQADLSKGDQARGLIE
EAGVCDILINNAGIQHVAPIDEFPVEKWDAIIAIMLSSAFHTTAVALPMMRDAGWGRVINISSAHGLTASPYKSAYVSAK
HGVVGMTKVVALETAKEPITANAICPGYVLTPLVESQIPDTAKKYDMSEEEVKQKVILERQPSKEFATTEQLGGTVAFLC
SAAADQITGTTISVDGGWTAL
>Mature_260_residues
AITTDLSGKTAVITGSNSGIGLGVARELARAGANVVLNSYTDTKKDHALAEEIAANFSVDARYIQADLSKGDQARGLIEE
AGVCDILINNAGIQHVAPIDEFPVEKWDAIIAIMLSSAFHTTAVALPMMRDAGWGRVINISSAHGLTASPYKSAYVSAKH
GVVGMTKVVALETAKEPITANAICPGYVLTPLVESQIPDTAKKYDMSEEEVKQKVILERQPSKEFATTEQLGGTVAFLCS
AAADQITGTTISVDGGWTAL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=31.640625, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI15277342, Length=278, Percent_Identity=29.8561151079137, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=28.3464566929134, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=28.9473684210526, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=30.3846153846154, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=28.2352941176471, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=31.6831683168317, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4503301, Length=264, Percent_Identity=30.3030303030303, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=25.6916996047431, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI7705855, Length=204, Percent_Identity=31.3725490196078, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=26.8041237113402, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI59889578, Length=240, Percent_Identity=28.75, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=30.3664921465969, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI225579078, Length=210, Percent_Identity=32.3809523809524, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=30.2857142857143, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=23.9024390243902, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI209862901, Length=237, Percent_Identity=27.4261603375527, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19923983, Length=237, Percent_Identity=27.4261603375527, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4557649, Length=182, Percent_Identity=31.8681318681319, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=217, Percent_Identity=26.2672811059908, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=32.03125, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=33.59375, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=33.587786259542, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=33.8461538461538, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=30.1158301158301, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=30.6201550387597, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=29.6153846153846, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=27.843137254902, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.1317829457364, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=26.2745098039216, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=25.78125, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=30.2325581395349, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=30.9160305343511, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=29.1187739463602, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=28.1853281853282, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=203, Percent_Identity=32.0197044334975, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=30.5555555555556, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=265, Percent_Identity=27.9245283018868, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=30.6122448979592, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=30.6532663316583, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=32.1243523316062, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=26.0536398467433, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=28.5185185185185, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=28.996282527881, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=27.3062730627306, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=267, Percent_Identity=26.5917602996255, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=254, Percent_Identity=26.3779527559055, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=27.3062730627306, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=221, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=276, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=256, Percent_Identity=27.34375, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=256, Percent_Identity=27.34375, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=31.0160427807487, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=31.6602316602317, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=30, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=26.6666666666667, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=29.2307692307692, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=28.90625, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=31.0344827586207, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28574402, Length=193, Percent_Identity=32.6424870466321, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24584744, Length=193, Percent_Identity=32.6424870466321, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24640442, Length=202, Percent_Identity=33.6633663366337, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859837, Length=259, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584748, Length=194, Percent_Identity=32.9896907216495, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI161076933, Length=194, Percent_Identity=32.9896907216495, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649181, Length=223, Percent_Identity=26.0089686098655, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=241, Percent_Identity=26.5560165975104, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=27.3255813953488, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI281364892, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27464; Mature: 27333

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITTDLSGKTAVITGSNSGIGLGVARELARAGANVVLNSYTDTKKDHALAEEIAANFSV
CEEEECCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCC
DARYIQADLSKGDQARGLIEEAGVCDILINNAGIQHVAPIDEFPVEKWDAIIAIMLSSAF
CHHHEEHHHCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
HTTAVALPMMRDAGWGRVINISSAHGLTASPYKSAYVSAKHGVVGMTKVVALETAKEPIT
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHEEECCCCCCHHHHHEEECCCCCCCC
ANAICPGYVLTPLVESQIPDTAKKYDMSEEEVKQKVILERQPSKEFATTEQLGGTVAFLC
CCCCCCCHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
SAAADQITGTTISVDGGWTAL
HHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure 
AITTDLSGKTAVITGSNSGIGLGVARELARAGANVVLNSYTDTKKDHALAEEIAANFSV
EEEECCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCC
DARYIQADLSKGDQARGLIEEAGVCDILINNAGIQHVAPIDEFPVEKWDAIIAIMLSSAF
CHHHEEHHHCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
HTTAVALPMMRDAGWGRVINISSAHGLTASPYKSAYVSAKHGVVGMTKVVALETAKEPIT
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHEEECCCCCCHHHHHEEECCCCCCCC
ANAICPGYVLTPLVESQIPDTAKKYDMSEEEVKQKVILERQPSKEFATTEQLGGTVAFLC
CCCCCCCHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
SAAADQITGTTISVDGGWTAL
HHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]