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The map label for this gene is btr [H]

Identifier: 89054698

GI number: 89054698

Start: 2215595

End: 2216377

Strand: Direct

Name: btr [H]

Synonym: Jann_2207

Alternate gene names: 89054698

Gene position: 2215595-2216377 (Clockwise)

Preceding gene: 89054695

Following gene: 89054700

Centisome position: 51.31

GC content: 59.39

Gene sequence:

>783_bases
ATGTTAAGATTTGTCATGAATGATGACCAACAAAGCTGTCTCGTCAGCCGTCTGTCGCGTTTCGTGGCCCTGACAGAGGC
GGAATGCGCCTTCATCGCCGAGATGGAAAAGGACGAACATGAACGGCGCAAGGGTCGGCCCGTCGTTCAGGTCGGAGACC
CGACGGAGGGCATCATGGTGCTGAAATCCGGGTGGGCAGTCGTGAAGGCCGATAGCTCGGATGGGCGCAGCCAGATCCTG
CGGGTCTATTTGCCCGGAGAGGTTATGGGGCTGGCGGAAATCGGCTCGTCCCACGCCAATCACCGCATTATCATGCAGAC
CGATGGGAAAATCTGCCCTTTCCCGCGCGCGGGGCTTGCGCCGCTTTATTCTGACTACCCTCGGTTGGGCGCGCTGCTCA
CCGCCGTGGGCAGCCTCGACCAAATCGCGTTGCGCCATCATGCCAGCAGCCTGGGGGCGATGGACGCCACGGGACGACTA
AAGTTCTGGCTTCTGCAGCTTCGGTCCCGGCTCGAGGTCGCTAATGTGGGCCTCGGGAACCGCTTCCGTGTGCCGTTCAG
CCAAGTTGAGATTGGGCAGGCTGTGGGCCTGACGTCGATCTATGTCAACAAGCTGCTCCGCCGGTTCATGGACGATGGCG
ATCTTGAGATTGAGCGTCCGTATTTCCGTCTTTTGAACCGAGAGCAGTGGGAGAGGGATTGTGAGTATGTGAACCCATTC
GTCGATATGGACACATCCTGGTTTCCCCCGGCCTACCCGGAGATACATGACAGCGCACCGTAG

Upstream 100 bases:

>100_bases
GCGGATGAGGTTCAAGATACTGTTTCACGGGTAAGGTCAAAGGGTGCAGACATCCGATCTGCCTTGAGGGCAAGATAATT
GGGCGGGCCCAGATTAATCC

Downstream 100 bases:

>100_bases
CACGACGCACCGTCTTGCCCTTCAGGCTATCGCATCCTCGTTGATCCCACCTGTCGCCAGATCAGTCATCGTGCGATCCC
CGTCATAGGATGCGTCAAGA

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLRFVMNDDQQSCLVSRLSRFVALTEAECAFIAEMEKDEHERRKGRPVVQVGDPTEGIMVLKSGWAVVKADSSDGRSQIL
RVYLPGEVMGLAEIGSSHANHRIIMQTDGKICPFPRAGLAPLYSDYPRLGALLTAVGSLDQIALRHHASSLGAMDATGRL
KFWLLQLRSRLEVANVGLGNRFRVPFSQVEIGQAVGLTSIYVNKLLRRFMDDGDLEIERPYFRLLNREQWERDCEYVNPF
VDMDTSWFPPAYPEIHDSAP

Sequences:

>Translated_260_residues
MLRFVMNDDQQSCLVSRLSRFVALTEAECAFIAEMEKDEHERRKGRPVVQVGDPTEGIMVLKSGWAVVKADSSDGRSQIL
RVYLPGEVMGLAEIGSSHANHRIIMQTDGKICPFPRAGLAPLYSDYPRLGALLTAVGSLDQIALRHHASSLGAMDATGRL
KFWLLQLRSRLEVANVGLGNRFRVPFSQVEIGQAVGLTSIYVNKLLRRFMDDGDLEIERPYFRLLNREQWERDCEYVNPF
VDMDTSWFPPAYPEIHDSAP
>Mature_260_residues
MLRFVMNDDQQSCLVSRLSRFVALTEAECAFIAEMEKDEHERRKGRPVVQVGDPTEGIMVLKSGWAVVKADSSDGRSQIL
RVYLPGEVMGLAEIGSSHANHRIIMQTDGKICPFPRAGLAPLYSDYPRLGALLTAVGSLDQIALRHHASSLGAMDATGRL
KFWLLQLRSRLEVANVGLGNRFRVPFSQVEIGQAVGLTSIYVNKLLRRFMDDGDLEIERPYFRLLNREQWERDCEYVNPF
VDMDTSWFPPAYPEIHDSAP

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=225, Percent_Identity=25.3333333333333, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 29311; Mature: 29311

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFVMNDDQQSCLVSRLSRFVALTEAECAFIAEMEKDEHERRKGRPVVQVGDPTEGIMV
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEE
LKSGWAVVKADSSDGRSQILRVYLPGEVMGLAEIGSSHANHRIIMQTDGKICPFPRAGLA
EECCCEEEEECCCCCCEEEEEEEECCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
PLYSDYPRLGALLTAVGSLDQIALRHHASSLGAMDATGRLKFWLLQLRSRLEVANVGLGN
HHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
RFRVPFSQVEIGQAVGLTSIYVNKLLRRFMDDGDLEIERPYFRLLNREQWERDCEYVNPF
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHCHHHHHHHHHHCCCH
VDMDTSWFPPAYPEIHDSAP
HCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRFVMNDDQQSCLVSRLSRFVALTEAECAFIAEMEKDEHERRKGRPVVQVGDPTEGIMV
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEE
LKSGWAVVKADSSDGRSQILRVYLPGEVMGLAEIGSSHANHRIIMQTDGKICPFPRAGLA
EECCCEEEEECCCCCCEEEEEEEECCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
PLYSDYPRLGALLTAVGSLDQIALRHHASSLGAMDATGRLKFWLLQLRSRLEVANVGLGN
HHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
RFRVPFSQVEIGQAVGLTSIYVNKLLRRFMDDGDLEIERPYFRLLNREQWERDCEYVNPF
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHCHHHHHHHHHHCCCH
VDMDTSWFPPAYPEIHDSAP
HCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]