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The map label for this gene is engA

Identifier: 89054660

GI number: 89054660

Start: 2174925

End: 2176364

Strand: Direct

Name: engA

Synonym: Jann_2169

Alternate gene names: 89054660

Gene position: 2174925-2176364 (Clockwise)

Preceding gene: 89054659

Following gene: 89054661

Centisome position: 50.37

GC content: 63.54

Gene sequence:

>1440_bases
ATGTCCTTCACGCTTGCCATCGTTGGCCGCCCCAATGTGGGCAAATCCACGCTATTCAACCGGCTCGTGGGCCGGAAGCT
GGCGCTGGTGGATGACCAGCCCGGGGTGACGCGCGATCTGCGGGAAGGGGCCGCGCGGCTGGCGGATCTGCGGTTTACGG
TGATTGACACGGCGGGACTGGAAGATGCCAACGACGACAGCCTGGAAGGGCGGATGCGCCGGTTGACGGAACGCGCCGTT
TCTATGGCGGATGCGACGCTGTTTGTGATGGATGCGCGCGCGGGCGTCACGACCAATGATCTGGTCTTCGCCGACATCCT
GCGCAAGTCGGGCCGCCCGGTGGTGCTGGCCGCCAACAAGGCGGAGGGCAATGCAGGCCAATCCGGTCTGCTGGACGCCT
ATTCCCTGGGTCTGGGCGAACCGCTGGCCCTGTCGGCGGAACACGGCGAGGGGATGGCCGATCTGGTTCAGGTCCTGCGC
CCGATGATCGAGGCCGCAGCGTCTGCCGAGGAGGCCGAGACGGATGTTGATGTGGAGGGTGAAGATCGCGTCATAACGCA
TTCGAAACCTTTGCAAATTGCAGTTGTGGGCAGGCCGAATGCGGGCAAATCCACGCTGATCAACCAGATCATCGGCGAAG
ACCGCCTGCTGACGGGGCCGGAGGCCGGGATTACCCGCGACGCCATCGGCCTGACATTTGAATGGGACGATGTTCCGATG
CGCATCTTCGACACGGCAGGTATGCGCAAACGGGCGAAGGTGCAGGAAAAGCTGGAGAAGTTGAGCGTCTCTGATGGGCT
GCGCGCGGTGAAGTTTGCGGAGGTGGTCGTGGTGCTGCTGGACGCCGCGATCCCGTTCGAGAGCCAGGATCTGCGGATTG
CCGATCTGGCGGAGCGGGAGGGGCGTGCGGTTGTCATTGCCGTCAACAAATGGGACGTGGAGCCTGAGAAACAACAGAAA
CTCAAAGACTTGCGCGTCGGGCTCGAACGGCTCCTGCCGCAATTGCGCGGCGCGCCTCTGGTGACGGTGTCGGCGAAGAC
GGGCAAGGGGCTGGACAAGCTCCACGCCGCGATCATGAAGATCCACGCGACCTGGAACACACGGATTTCCACCGCGCGCC
TGAACCAATGGCTGGCCGCGATGATCGAGGCGCATCCGCCCCCCGCGCCGGGCGGTCGGCGCATCAAACTGCGCTACATG
ACCCAGGCCAAGACGCGGCCCCCGGGGTTTGTGGTCATGTGTTCGCACCCGCAGAACCTGCCGGAGGCGTATTCGCGCTA
TCTGGTCAACGGGTTGCGGCAGGATTTTGATATGCCCGGCACGCCGATCCGGCTGTGGATGCGCAGCCAGGCCGATGACA
ACCCCTACAAGAACCGCAAGAAATCAACACCCTCGCGCCTCAACAAGCACGTCCGAAAGGGCGAGACGAAGAAGGGATGA

Upstream 100 bases:

>100_bases
ACCGGTCGGCCTTCTCCAACGCGCTGGAGACGGCGCTGCGGCGCTTGAAATAGGGACAAAAGGGGCGTAGGTGCGCCTCT
TCTGTTTAAGGTGCCTGCCC

Downstream 100 bases:

>100_bases
CCCGGCGCGGGCTGCTCAGGGGCGGACTTTTTCTGGCCGGGGCGTGGGCGCTGATGGCGCGACCCTGGTCGTGGGGGCGC
GCCGACGATATCACGACAGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSFTLAIVGRPNVGKSTLFNRLVGRKLALVDDQPGVTRDLREGAARLADLRFTVIDTAGLEDANDDSLEGRMRRLTERAV
SMADATLFVMDARAGVTTNDLVFADILRKSGRPVVLAANKAEGNAGQSGLLDAYSLGLGEPLALSAEHGEGMADLVQVLR
PMIEAAASAEEAETDVDVEGEDRVITHSKPLQIAVVGRPNAGKSTLINQIIGEDRLLTGPEAGITRDAIGLTFEWDDVPM
RIFDTAGMRKRAKVQEKLEKLSVSDGLRAVKFAEVVVVLLDAAIPFESQDLRIADLAEREGRAVVIAVNKWDVEPEKQQK
LKDLRVGLERLLPQLRGAPLVTVSAKTGKGLDKLHAAIMKIHATWNTRISTARLNQWLAAMIEAHPPPAPGGRRIKLRYM
TQAKTRPPGFVVMCSHPQNLPEAYSRYLVNGLRQDFDMPGTPIRLWMRSQADDNPYKNRKKSTPSRLNKHVRKGETKKG

Sequences:

>Translated_479_residues
MSFTLAIVGRPNVGKSTLFNRLVGRKLALVDDQPGVTRDLREGAARLADLRFTVIDTAGLEDANDDSLEGRMRRLTERAV
SMADATLFVMDARAGVTTNDLVFADILRKSGRPVVLAANKAEGNAGQSGLLDAYSLGLGEPLALSAEHGEGMADLVQVLR
PMIEAAASAEEAETDVDVEGEDRVITHSKPLQIAVVGRPNAGKSTLINQIIGEDRLLTGPEAGITRDAIGLTFEWDDVPM
RIFDTAGMRKRAKVQEKLEKLSVSDGLRAVKFAEVVVVLLDAAIPFESQDLRIADLAEREGRAVVIAVNKWDVEPEKQQK
LKDLRVGLERLLPQLRGAPLVTVSAKTGKGLDKLHAAIMKIHATWNTRISTARLNQWLAAMIEAHPPPAPGGRRIKLRYM
TQAKTRPPGFVVMCSHPQNLPEAYSRYLVNGLRQDFDMPGTPIRLWMRSQADDNPYKNRKKSTPSRLNKHVRKGETKKG
>Mature_478_residues
SFTLAIVGRPNVGKSTLFNRLVGRKLALVDDQPGVTRDLREGAARLADLRFTVIDTAGLEDANDDSLEGRMRRLTERAVS
MADATLFVMDARAGVTTNDLVFADILRKSGRPVVLAANKAEGNAGQSGLLDAYSLGLGEPLALSAEHGEGMADLVQVLRP
MIEAAASAEEAETDVDVEGEDRVITHSKPLQIAVVGRPNAGKSTLINQIIGEDRLLTGPEAGITRDAIGLTFEWDDVPMR
IFDTAGMRKRAKVQEKLEKLSVSDGLRAVKFAEVVVVLLDAAIPFESQDLRIADLAEREGRAVVIAVNKWDVEPEKQQKL
KDLRVGLERLLPQLRGAPLVTVSAKTGKGLDKLHAAIMKIHATWNTRISTARLNQWLAAMIEAHPPPAPGGRRIKLRYMT
QAKTRPPGFVVMCSHPQNLPEAYSRYLVNGLRQDFDMPGTPIRLWMRSQADDNPYKNRKKSTPSRLNKHVRKGETKKG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=496, Percent_Identity=37.5, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI2367268, Length=169, Percent_Identity=28.4023668639053, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788919, Length=167, Percent_Identity=26.9461077844311, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_JANSC (Q28QC6)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510111.1
- ProteinModelPortal:   Q28QC6
- SMR:   Q28QC6
- STRING:   Q28QC6
- GeneID:   3934623
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2169
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q28QC6
- ProtClustDB:   PRK00093
- BioCyc:   JSP290400:JANN_2169-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR001806
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00449
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 52514; Mature: 52383

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTLAIVGRPNVGKSTLFNRLVGRKLALVDDQPGVTRDLREGAARLADLRFTVIDTAGL
CCEEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEECCC
EDANDDSLEGRMRRLTERAVSMADATLFVMDARAGVTTNDLVFADILRKSGRPVVLAANK
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECC
AEGNAGQSGLLDAYSLGLGEPLALSAEHGEGMADLVQVLRPMIEAAASAEEAETDVDVEG
CCCCCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
EDRVITHSKPLQIAVVGRPNAGKSTLINQIIGEDRLLTGPEAGITRDAIGLTFEWDDVPM
CCEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCCE
RIFDTAGMRKRAKVQEKLEKLSVSDGLRAVKFAEVVVVLLDAAIPFESQDLRIADLAERE
EEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHCCC
GRAVVIAVNKWDVEPEKQQKLKDLRVGLERLLPQLRGAPLVTVSAKTGKGLDKLHAAIMK
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHH
IHATWNTRISTARLNQWLAAMIEAHPPPAPGGRRIKLRYMTQAKTRPPGFVVMCSHPQNL
EEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCC
PEAYSRYLVNGLRQDFDMPGTPIRLWMRSQADDNPYKNRKKSTPSRLNKHVRKGETKKG
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SFTLAIVGRPNVGKSTLFNRLVGRKLALVDDQPGVTRDLREGAARLADLRFTVIDTAGL
CEEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHEEEEEEEECCC
EDANDDSLEGRMRRLTERAVSMADATLFVMDARAGVTTNDLVFADILRKSGRPVVLAANK
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEECC
AEGNAGQSGLLDAYSLGLGEPLALSAEHGEGMADLVQVLRPMIEAAASAEEAETDVDVEG
CCCCCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
EDRVITHSKPLQIAVVGRPNAGKSTLINQIIGEDRLLTGPEAGITRDAIGLTFEWDDVPM
CCEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCCE
RIFDTAGMRKRAKVQEKLEKLSVSDGLRAVKFAEVVVVLLDAAIPFESQDLRIADLAERE
EEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHCCC
GRAVVIAVNKWDVEPEKQQKLKDLRVGLERLLPQLRGAPLVTVSAKTGKGLDKLHAAIMK
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHH
IHATWNTRISTARLNQWLAAMIEAHPPPAPGGRRIKLRYMTQAKTRPPGFVVMCSHPQNL
EEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEECCCCCCC
PEAYSRYLVNGLRQDFDMPGTPIRLWMRSQADDNPYKNRKKSTPSRLNKHVRKGETKKG
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA