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The map label for this gene is xylB [H]

Identifier: 89054605

GI number: 89054605

Start: 2122144

End: 2123631

Strand: Direct

Name: xylB [H]

Synonym: Jann_2114

Alternate gene names: 89054605

Gene position: 2122144-2123631 (Clockwise)

Preceding gene: 89054604

Following gene: 89054606

Centisome position: 49.15

GC content: 63.04

Gene sequence:

>1488_bases
GTGAGCTATACCCTTGGCGTTGATATCGGCACCTACGAGACCAAGGGCGTGTTGGTGGATGCCGCCGGTTGCGTGGTTGC
CATGGCCACCGCAGCCCATGACATGCTGGTGCCCCACCCCGGATGGGCGGAGCATCGGCCAGAGCAGGATTGGTGGGGGG
ATTTCGTTTCTGTCACCCGTGAGGTGTTGACGAAATCAGGTGTCGCACCGGACCAGATCAAGGCCGTCGCCTGTTCGGCC
ATCGGGCCGTGCATGTTACCGGTGGATGATGGTGGAGCGCCCTTGATGAACGGCGTTCTCTATGGGGTCGATACCCGCGC
CATGGCGGAGGTGCAGGCCCTGACGGCTCGGATCGGGGAGGACGTGATCCTTGACCGATGCGGCAACGCGCTGACGTCGC
AATCGGTCGGGCCCAAGATCCTGTGGCTCAAGACACACCGTCCGGACATCTACGAAAAGACCGCCAAGATCCTGACTGCC
ACCAGTTTTCTGGTGCATCGGCTGACCGGCGAATTCGTAATTGATCATTACACGGCTGCCAATTTCTCGCCGCTATATGA
CGTATCCACGCAAGACTGGTGTTTCGATCTGGCCCCTGAGATCGCAACTCCCCAGATGCTGCCACGCCTGCTGTGGTCAT
CCGAGATTGCGGGCCATATCACCGCCCGTGCGGCGACCACCACGGGCCTGGCGGAAGGCACACCCGTGACCGCAGGTACG
ATTGACGCAGCAGCAGAAGCGTTAAGCGTCGGCGTGCGGCAATCGGGCGACATGATGATGATGTATGGCTCCACCATCTT
TGTGATCACCTTGACGCCAGACCGCGTGCGCGACGCGCGGCTGTGGTACGCACCATGGCTGTTCCCGGGCCAACACGCAT
CGATGGCGGGTCTGGCCACATCGGGCACACTGACCCACTGGTTCCGCGACCAATTCGCGGCGGAACTGCCGCGCGATACG
GCCTTTCCGACCCTTGCAGCCGAGGCAGAGGCCATCGCTCCGGGGGCCGGCGGCCTGTTGTTTCTGCCCTATTTCTCAGG
CGAACGAACGCCGCTCCACGATCCGCTCGCCAAGGGCGCGTTCTTCGGCATGAACCTGACCCACACCCGCGCCCACCTGT
TCCGCGCGGTGATCGAGGGCATCGCCCATGGCACGGCCCATGTGGTGGAAACGTACCGGGATGTTGAGGCCGCGCCCTCG
CGCATTCTGGCCGTCGGCGGCGGCACCAAGAATGCGCTGTGGTTGCAGGCGACGTCGGACACGTCTGGCCTGGATCAGAT
CCTGTGCGACAAGACAATCGGGGCCAGCTACGGCGACGCTTTTCTGGCGCGGATCGCGATCGGTGAGGCAGATATCGAGG
ACATTGCCACATGGAACCCGGTCCAGCGCACCGTGACCGCGCAGCGGGAACCGGCCTATGAAAGGGCCTATCCGCTGTTT
CGGCGCCTCTACGAGCAAACCAAAGACATCGCGGCGGAGTTGGGGTGA

Upstream 100 bases:

>100_bases
CCCTTGAGATGTGTCAGATCAGCGATCTGGAGGCTTTGTCGCGGTTGCTGGTCGCGGGGCTGGCCCGGATCGGCCCGGAT
TTTCCACTGGAGCGATGGGC

Downstream 100 bases:

>100_bases
ACGGCGACTCTGCGGGCTTGGCGGAGCGTCCAAATCTCAACACCGATGTCCGCTTCCATGACGAAGCCGCCGTCGCCTGG
TTGGCAACCAGCATCTGTTT

Product: carbohydrate kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSYTLGVDIGTYETKGVLVDAAGCVVAMATAAHDMLVPHPGWAEHRPEQDWWGDFVSVTREVLTKSGVAPDQIKAVACSA
IGPCMLPVDDGGAPLMNGVLYGVDTRAMAEVQALTARIGEDVILDRCGNALTSQSVGPKILWLKTHRPDIYEKTAKILTA
TSFLVHRLTGEFVIDHYTAANFSPLYDVSTQDWCFDLAPEIATPQMLPRLLWSSEIAGHITARAATTTGLAEGTPVTAGT
IDAAAEALSVGVRQSGDMMMMYGSTIFVITLTPDRVRDARLWYAPWLFPGQHASMAGLATSGTLTHWFRDQFAAELPRDT
AFPTLAAEAEAIAPGAGGLLFLPYFSGERTPLHDPLAKGAFFGMNLTHTRAHLFRAVIEGIAHGTAHVVETYRDVEAAPS
RILAVGGGTKNALWLQATSDTSGLDQILCDKTIGASYGDAFLARIAIGEADIEDIATWNPVQRTVTAQREPAYERAYPLF
RRLYEQTKDIAAELG

Sequences:

>Translated_495_residues
MSYTLGVDIGTYETKGVLVDAAGCVVAMATAAHDMLVPHPGWAEHRPEQDWWGDFVSVTREVLTKSGVAPDQIKAVACSA
IGPCMLPVDDGGAPLMNGVLYGVDTRAMAEVQALTARIGEDVILDRCGNALTSQSVGPKILWLKTHRPDIYEKTAKILTA
TSFLVHRLTGEFVIDHYTAANFSPLYDVSTQDWCFDLAPEIATPQMLPRLLWSSEIAGHITARAATTTGLAEGTPVTAGT
IDAAAEALSVGVRQSGDMMMMYGSTIFVITLTPDRVRDARLWYAPWLFPGQHASMAGLATSGTLTHWFRDQFAAELPRDT
AFPTLAAEAEAIAPGAGGLLFLPYFSGERTPLHDPLAKGAFFGMNLTHTRAHLFRAVIEGIAHGTAHVVETYRDVEAAPS
RILAVGGGTKNALWLQATSDTSGLDQILCDKTIGASYGDAFLARIAIGEADIEDIATWNPVQRTVTAQREPAYERAYPLF
RRLYEQTKDIAAELG
>Mature_494_residues
SYTLGVDIGTYETKGVLVDAAGCVVAMATAAHDMLVPHPGWAEHRPEQDWWGDFVSVTREVLTKSGVAPDQIKAVACSAI
GPCMLPVDDGGAPLMNGVLYGVDTRAMAEVQALTARIGEDVILDRCGNALTSQSVGPKILWLKTHRPDIYEKTAKILTAT
SFLVHRLTGEFVIDHYTAANFSPLYDVSTQDWCFDLAPEIATPQMLPRLLWSSEIAGHITARAATTTGLAEGTPVTAGTI
DAAAEALSVGVRQSGDMMMMYGSTIFVITLTPDRVRDARLWYAPWLFPGQHASMAGLATSGTLTHWFRDQFAAELPRDTA
FPTLAAEAEAIAPGAGGLLFLPYFSGERTPLHDPLAKGAFFGMNLTHTRAHLFRAVIEGIAHGTAHVVETYRDVEAAPSR
ILAVGGGTKNALWLQATSDTSGLDQILCDKTIGASYGDAFLARIAIGEADIEDIATWNPVQRTVTAQREPAYERAYPLFR
RLYEQTKDIAAELG

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=561, Percent_Identity=25.3119429590018, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI42794763, Length=452, Percent_Identity=23.6725663716814, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI88196792, Length=449, Percent_Identity=22.71714922049, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI41393575, Length=408, Percent_Identity=24.5098039215686, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1789987, Length=492, Percent_Identity=30.2845528455285, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1790005, Length=509, Percent_Identity=27.3084479371316, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1787789, Length=447, Percent_Identity=28.4116331096197, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1790361, Length=466, Percent_Identity=25.3218884120172, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1789168, Length=467, Percent_Identity=25.0535331905782, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789138, Length=443, Percent_Identity=21.2189616252822, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535599, Length=444, Percent_Identity=25, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24657106, Length=488, Percent_Identity=25, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24657102, Length=488, Percent_Identity=25, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357867, Length=519, Percent_Identity=22.7360308285164, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656367, Length=503, Percent_Identity=23.2604373757455, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356323, Length=380, Percent_Identity=24.7368421052632, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24656372, Length=374, Percent_Identity=23.5294117647059, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 53350; Mature: 53219

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTLGVDIGTYETKGVLVDAAGCVVAMATAAHDMLVPHPGWAEHRPEQDWWGDFVSVTR
CCEEEEEEECCEECCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
EVLTKSGVAPDQIKAVACSAIGPCMLPVDDGGAPLMNGVLYGVDTRAMAEVQALTARIGE
HHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHCCEEECCCHHHHHHHHHHHHHHCH
DVILDRCGNALTSQSVGPKILWLKTHRPDIYEKTAKILTATSFLVHRLTGEFVIDHYTAA
HHHHHHCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
NFSPLYDVSTQDWCFDLAPEIATPQMLPRLLWSSEIAGHITARAATTTGLAEGTPVTAGT
CCCCEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCCH
IDAAAEALSVGVRQSGDMMMMYGSTIFVITLTPDRVRDARLWYAPWLFPGQHASMAGLAT
HHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHCCCC
SGTLTHWFRDQFAAELPRDTAFPTLAAEAEAIAPGAGGLLFLPYFSGERTPLHDPLAKGA
CCCHHHHHHHHHHHHCCCCCCCCCHHCCCHHCCCCCCCEEEEEEECCCCCCCCCHHHCCE
FFGMNLTHTRAHLFRAVIEGIAHGTAHVVETYRDVEAAPSRILAVGGGTKNALWLQATSD
EECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCC
TSGLDQILCDKTIGASYGDAFLARIAIGEADIEDIATWNPVQRTVTAQREPAYERAYPLF
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHH
RRLYEQTKDIAAELG
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SYTLGVDIGTYETKGVLVDAAGCVVAMATAAHDMLVPHPGWAEHRPEQDWWGDFVSVTR
CEEEEEEECCEECCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
EVLTKSGVAPDQIKAVACSAIGPCMLPVDDGGAPLMNGVLYGVDTRAMAEVQALTARIGE
HHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHCCEEECCCHHHHHHHHHHHHHHCH
DVILDRCGNALTSQSVGPKILWLKTHRPDIYEKTAKILTATSFLVHRLTGEFVIDHYTAA
HHHHHHCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
NFSPLYDVSTQDWCFDLAPEIATPQMLPRLLWSSEIAGHITARAATTTGLAEGTPVTAGT
CCCCEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCCH
IDAAAEALSVGVRQSGDMMMMYGSTIFVITLTPDRVRDARLWYAPWLFPGQHASMAGLAT
HHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHCCCC
SGTLTHWFRDQFAAELPRDTAFPTLAAEAEAIAPGAGGLLFLPYFSGERTPLHDPLAKGA
CCCHHHHHHHHHHHHCCCCCCCCCHHCCCHHCCCCCCCEEEEEEECCCCCCCCCHHHCCE
FFGMNLTHTRAHLFRAVIEGIAHGTAHVVETYRDVEAAPSRILAVGGGTKNALWLQATSD
EECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCC
TSGLDQILCDKTIGASYGDAFLARIAIGEADIEDIATWNPVQRTVTAQREPAYERAYPLF
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHH
RRLYEQTKDIAAELG
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1660563 [H]