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The map label for this gene is rhmD [H]

Identifier: 89054595

GI number: 89054595

Start: 2112790

End: 2114085

Strand: Direct

Name: rhmD [H]

Synonym: Jann_2104

Alternate gene names: 89054595

Gene position: 2112790-2114085 (Clockwise)

Preceding gene: 89054594

Following gene: 89054598

Centisome position: 48.93

GC content: 61.19

Gene sequence:

>1296_bases
ATGTCAGCGCGCATCACCCATGTCACAACCCATGATGTCCGTTTTCCGACGAGCCGTACTCTGGATGGCTCTGACGCGAT
GAACGAGGCGCCTGACTACTCTGCTGCTTATGTCGTGTTGCACGTCGATCATGGTCCCGACGGCCATGGCATGACCTTCA
CCATCGGGCGCGGGAATGAGATCTGTTGTTCCGCAATCGAAGCGCTTGGGACGCTTCTTGTGGGCCGCGAGGTTGAGGGG
CTGTTCGCGGATATGGGCGCGGTCTGGAAACTGGTAACAGGTGACAGTCAGCTGCGCTGGACCGGCCCGGAAAAGGGCGT
GATCCACCTTGCCGGGGCTGCCGTGATGAACGCGGTCTGGGACATGTATGCCAAACATGCGGGCCAACCGGTCTGGCGTT
TGTTGGCGACGATGTCGCCCGCCGATATGGTGGCGCTGGTGGATTGGCGCTATCTGGCTGACGCGCTGCCCCCTGAAGAG
GCGCTGGAGCGCTTGCAGGACAAGGCCCCGGGACGGGCTGCGCGGATGGCGGAGATGGAGGCCAATGGCTATCCCGCCTA
TACGACCTCCGCCGGGTGGCTCGGCTATTCAGACGAAAAGATCAAGACGCTGATGCGCGCGGCGCTGGCGGACGGCTGGA
CCCATTTCAAGATGAAGGTCGGCGCGAATATCGAGGATGACATCCGCCGCGCGGCGATCATCCGCGAAGAGATCGGGCCG
GAGCGGTTCTTGATGATGGATGCAAATCAGGTCTGGGGCGTGGAAGAGACCATTTCCAACATGTCCCGGCTGGCCACATT
CGACCCGTGGTGGATCGAAGAGCCGACCAGCCCCGACGATATCCTTGGCCATGCCCGCATCGCACGCGAGGTTGCGCCGA
TCAAGGTCGCAACCGGCGAGCATTGCCACAACGCCGTCATGTTCAAGCAGTTGTTGCAGGCCGATGCGATCAGCTTCTGT
CAGGTCGACAGCTGCCGTCTGGCTGGTCCGAATGAGATTCTGGCTGTCATGCTGATGGCCGATAAATTCGGCGTTCCCGT
CTGCCCCCACGCGGGTGGTGTCGGCTTGTGCGAGTTGATCCAGCACATGAGTTTTGTGGACTACATCGCGGTGTCCGCGA
ACCTTGATAATCGCGTGCTGGAATATGTGGACCATTTGCATGAGCATTTCGTCGACCCGGTTCGCACCAAGAACGGTCGG
TATCTGCCACCCGCAATGCCCGGCTTCTCGGTGGAGATGAAACCCCACAGCATCGCGCGCCACACGTTCCCCGGCGGCGC
GGTGTGGCAAGCCTAG

Upstream 100 bases:

>100_bases
ATGCCGTTTCCGAATTCTTGCTATTGCCTGCCCATTCACCGCTGACTAACATGCTAGCATGAAAGTCGGTCAGAGGCCGA
TGTTACAATCAGAGGGTCCC

Downstream 100 bases:

>100_bases
GCGGATGATCTCCGAGGCGCACCGCCATCTCTGCACTCGATATCTGGCCTAGGCGTCCCAGGCGATAGTTTGTTGCCGCT
GCGTCCCGAGGCCCGCGATG

Product: mandelate racemase/muconate lactonizing enzyme

Products: NA

Alternate protein names: RhamD [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSARITHVTTHDVRFPTSRTLDGSDAMNEAPDYSAAYVVLHVDHGPDGHGMTFTIGRGNEICCSAIEALGTLLVGREVEG
LFADMGAVWKLVTGDSQLRWTGPEKGVIHLAGAAVMNAVWDMYAKHAGQPVWRLLATMSPADMVALVDWRYLADALPPEE
ALERLQDKAPGRAARMAEMEANGYPAYTTSAGWLGYSDEKIKTLMRAALADGWTHFKMKVGANIEDDIRRAAIIREEIGP
ERFLMMDANQVWGVEETISNMSRLATFDPWWIEEPTSPDDILGHARIAREVAPIKVATGEHCHNAVMFKQLLQADAISFC
QVDSCRLAGPNEILAVMLMADKFGVPVCPHAGGVGLCELIQHMSFVDYIAVSANLDNRVLEYVDHLHEHFVDPVRTKNGR
YLPPAMPGFSVEMKPHSIARHTFPGGAVWQA

Sequences:

>Translated_431_residues
MSARITHVTTHDVRFPTSRTLDGSDAMNEAPDYSAAYVVLHVDHGPDGHGMTFTIGRGNEICCSAIEALGTLLVGREVEG
LFADMGAVWKLVTGDSQLRWTGPEKGVIHLAGAAVMNAVWDMYAKHAGQPVWRLLATMSPADMVALVDWRYLADALPPEE
ALERLQDKAPGRAARMAEMEANGYPAYTTSAGWLGYSDEKIKTLMRAALADGWTHFKMKVGANIEDDIRRAAIIREEIGP
ERFLMMDANQVWGVEETISNMSRLATFDPWWIEEPTSPDDILGHARIAREVAPIKVATGEHCHNAVMFKQLLQADAISFC
QVDSCRLAGPNEILAVMLMADKFGVPVCPHAGGVGLCELIQHMSFVDYIAVSANLDNRVLEYVDHLHEHFVDPVRTKNGR
YLPPAMPGFSVEMKPHSIARHTFPGGAVWQA
>Mature_430_residues
SARITHVTTHDVRFPTSRTLDGSDAMNEAPDYSAAYVVLHVDHGPDGHGMTFTIGRGNEICCSAIEALGTLLVGREVEGL
FADMGAVWKLVTGDSQLRWTGPEKGVIHLAGAAVMNAVWDMYAKHAGQPVWRLLATMSPADMVALVDWRYLADALPPEEA
LERLQDKAPGRAARMAEMEANGYPAYTTSAGWLGYSDEKIKTLMRAALADGWTHFKMKVGANIEDDIRRAAIIREEIGPE
RFLMMDANQVWGVEETISNMSRLATFDPWWIEEPTSPDDILGHARIAREVAPIKVATGEHCHNAVMFKQLLQADAISFCQ
VDSCRLAGPNEILAVMLMADKFGVPVCPHAGGVGLCELIQHMSFVDYIAVSANLDNRVLEYVDHLHEHFVDPVRTKNGRY
LPPAMPGFSVEMKPHSIARHTFPGGAVWQA

Specific function: Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR) [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=434, Percent_Identity=55.9907834101382, Blast_Score=519, Evalue=1e-147,
Organism=Homo sapiens, GI42544117, Length=410, Percent_Identity=55.3658536585366, Blast_Score=486, Evalue=1e-137,
Organism=Homo sapiens, GI186972148, Length=357, Percent_Identity=57.1428571428571, Blast_Score=438, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.90 [H]

Molecular weight: Translated: 47413; Mature: 47282

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARITHVTTHDVRFPTSRTLDGSDAMNEAPDYSAAYVVLHVDHGPDGHGMTFTIGRGNE
CCCEEEEEEECCEECCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCH
ICCSAIEALGTLLVGREVEGLFADMGAVWKLVTGDSQLRWTGPEKGVIHLAGAAVMNAVW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCEEEECCCCCCEEEEHHHHHHHHHH
DMYAKHAGQPVWRLLATMSPADMVALVDWRYLADALPPEEALERLQDKAPGRAARMAEME
HHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHC
ANGYPAYTTSAGWLGYSDEKIKTLMRAALADGWTHFKMKVGANIEDDIRRAAIIREEIGP
CCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
ERFLMMDANQVWGVEETISNMSRLATFDPWWIEEPTSPDDILGHARIAREVAPIKVATGE
CEEEEECCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCC
HCHNAVMFKQLLQADAISFCQVDSCRLAGPNEILAVMLMADKFGVPVCPHAGGVGLCELI
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QHMSFVDYIAVSANLDNRVLEYVDHLHEHFVDPVRTKNGRYLPPAMPGFSVEMKPHSIAR
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCHHHHH
HTFPGGAVWQA
CCCCCCCCCCC
>Mature Secondary Structure 
SARITHVTTHDVRFPTSRTLDGSDAMNEAPDYSAAYVVLHVDHGPDGHGMTFTIGRGNE
CCEEEEEEECCEECCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCH
ICCSAIEALGTLLVGREVEGLFADMGAVWKLVTGDSQLRWTGPEKGVIHLAGAAVMNAVW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCEEEECCCCCCEEEEHHHHHHHHHH
DMYAKHAGQPVWRLLATMSPADMVALVDWRYLADALPPEEALERLQDKAPGRAARMAEME
HHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHC
ANGYPAYTTSAGWLGYSDEKIKTLMRAALADGWTHFKMKVGANIEDDIRRAAIIREEIGP
CCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
ERFLMMDANQVWGVEETISNMSRLATFDPWWIEEPTSPDDILGHARIAREVAPIKVATGE
CEEEEECCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCC
HCHNAVMFKQLLQADAISFCQVDSCRLAGPNEILAVMLMADKFGVPVCPHAGGVGLCELI
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QHMSFVDYIAVSANLDNRVLEYVDHLHEHFVDPVRTKNGRYLPPAMPGFSVEMKPHSIAR
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCHHHHH
HTFPGGAVWQA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA