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The map label for this gene is glpR [H]

Identifier: 89054562

GI number: 89054562

Start: 2080485

End: 2081249

Strand: Direct

Name: glpR [H]

Synonym: Jann_2071

Alternate gene names: 89054562

Gene position: 2080485-2081249 (Clockwise)

Preceding gene: 89054559

Following gene: 89054563

Centisome position: 48.18

GC content: 63.79

Gene sequence:

>765_bases
GTGCCACAGGGATTCAGGCAGGCCGAGATACTGGAGATCGCCGCGCGCGACGGCAAAGTCACCGTCGAGGGGCTGGCGGC
GCATTTTTCCGTCACGCTGCAAACCATTCGCCGGGATCTTTCGGAACTGGATCAGGCGGGGCTCCTCAACCGGGTCCACG
GCGGCGCAATGCCCGCATCCGGCACCAGCAATTTCGCCTATGAAGACCGGCGCGCCCTGCAGACGGAGGCCAAGGATCAG
ATCGCACGGGCCTGTGCGGCGGCCATCCCCGACGATTGCTCGGTGTTCCTGAATATCGGCACCAGCACCGAGGCCGTGGC
AGGTCGGCTGACCCGGCATCAGAACCTGCTGGTGATCACCAACAACCTCAACGTGGCCAATATCCTGTCGCGCGCGCCGG
GTGTGGAGATCTACGTGACCGGCGGCACCCTGCGCCGCGCCGATGGCGGGCTGATCGGGCCATTGGCTATTGATGCGATC
AACAACTTCAAGTTCGATTATGCGGTGATCGGCTGTTCCGCGCTGGATCTGGACGGGGATGTGCTGGATTTCGATGTGCA
GGAGGTGGGCGTCAGCCAGGCCATCGTGGCCCGCGCACGCAAGACCTATCTGGTGGCGGATCATTCAAAGTTTGAACGCA
CGGCGCCCGCACGGATCTGCTCGCTGGCGCAGATCGACGGGTTCTTTACTGACCGCGCCCTTGATCCCGACCTCGCCGCG
CGGTGTGAGGCCTGGCAGGTCACTGTCAGCGTTTCCGATGGCTGA

Upstream 100 bases:

>100_bases
CGCCAAAAACCGATGACGCGGCCAAGGCCTTGGCGGTTTGCCATGCCGGGCGTCCGGCGTGTAGAGAGATGCGGGGCCAA
TCAATCGGGGCGGAGGTGCT

Downstream 100 bases:

>100_bases
GACGCGCCCGGATGCGGGGACCCCGTGACCTTTCGCGTGCCCTGCGCTATGGCAGCCGCACCCAATGCGGAGAGACCCCA
TGACCACCATCGCCCTTGTC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MPQGFRQAEILEIAARDGKVTVEGLAAHFSVTLQTIRRDLSELDQAGLLNRVHGGAMPASGTSNFAYEDRRALQTEAKDQ
IARACAAAIPDDCSVFLNIGTSTEAVAGRLTRHQNLLVITNNLNVANILSRAPGVEIYVTGGTLRRADGGLIGPLAIDAI
NNFKFDYAVIGCSALDLDGDVLDFDVQEVGVSQAIVARARKTYLVADHSKFERTAPARICSLAQIDGFFTDRALDPDLAA
RCEAWQVTVSVSDG

Sequences:

>Translated_254_residues
MPQGFRQAEILEIAARDGKVTVEGLAAHFSVTLQTIRRDLSELDQAGLLNRVHGGAMPASGTSNFAYEDRRALQTEAKDQ
IARACAAAIPDDCSVFLNIGTSTEAVAGRLTRHQNLLVITNNLNVANILSRAPGVEIYVTGGTLRRADGGLIGPLAIDAI
NNFKFDYAVIGCSALDLDGDVLDFDVQEVGVSQAIVARARKTYLVADHSKFERTAPARICSLAQIDGFFTDRALDPDLAA
RCEAWQVTVSVSDG
>Mature_253_residues
PQGFRQAEILEIAARDGKVTVEGLAAHFSVTLQTIRRDLSELDQAGLLNRVHGGAMPASGTSNFAYEDRRALQTEAKDQI
ARACAAAIPDDCSVFLNIGTSTEAVAGRLTRHQNLLVITNNLNVANILSRAPGVEIYVTGGTLRRADGGLIGPLAIDAIN
NFKFDYAVIGCSALDLDGDVLDFDVQEVGVSQAIVARARKTYLVADHSKFERTAPARICSLAQIDGFFTDRALDPDLAAR
CEAWQVTVSVSDG

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=45.021645021645, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082344, Length=244, Percent_Identity=40.5737704918033, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=34.6774193548387, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789519, Length=235, Percent_Identity=32.3404255319149, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=28.8135593220339, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790753, Length=210, Percent_Identity=32.3809523809524, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI226510968, Length=237, Percent_Identity=29.535864978903, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=27.0742358078603, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787540, Length=249, Percent_Identity=25.3012048192771, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787063, Length=229, Percent_Identity=25.3275109170306, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790635, Length=255, Percent_Identity=24.7058823529412, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27189; Mature: 27058

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGFRQAEILEIAARDGKVTVEGLAAHFSVTLQTIRRDLSELDQAGLLNRVHGGAMPAS
CCCCCCHHHHHHEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTSNFAYEDRRALQTEAKDQIARACAAAIPDDCSVFLNIGTSTEAVAGRLTRHQNLLVIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVANILSRAPGVEIYVTGGTLRRADGGLIGPLAIDAINNFKFDYAVIGCSALDLDGD
CCCCHHHHHHCCCCCEEEEECCEEEECCCCEECHHHHHHHHCCCEEEEEEEEEEECCCCC
VLDFDVQEVGVSQAIVARARKTYLVADHSKFERTAPARICSLAQIDGFFTDRALDPDLAA
EEECCHHHHCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RCEAWQVTVSVSDG
CCEEEEEEEEECCC
>Mature Secondary Structure 
PQGFRQAEILEIAARDGKVTVEGLAAHFSVTLQTIRRDLSELDQAGLLNRVHGGAMPAS
CCCCCHHHHHHEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTSNFAYEDRRALQTEAKDQIARACAAAIPDDCSVFLNIGTSTEAVAGRLTRHQNLLVIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVANILSRAPGVEIYVTGGTLRRADGGLIGPLAIDAINNFKFDYAVIGCSALDLDGD
CCCCHHHHHHCCCCCEEEEECCEEEECCCCEECHHHHHHHHCCCEEEEEEEEEEECCCCC
VLDFDVQEVGVSQAIVARARKTYLVADHSKFERTAPARICSLAQIDGFFTDRALDPDLAA
EEECCHHHHCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RCEAWQVTVSVSDG
CCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]