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The map label for this gene is coaD

Identifier: 89054407

GI number: 89054407

Start: 1905160

End: 1905657

Strand: Direct

Name: coaD

Synonym: Jann_1916

Alternate gene names: 89054407

Gene position: 1905160-1905657 (Clockwise)

Preceding gene: 89054406

Following gene: 89054408

Centisome position: 44.12

GC content: 59.24

Gene sequence:

>498_bases
ATGACGCGCACAGGGCTTTATCCGGGAACGTTCGACCCAATCACACTGGGCCATGTCGATGTGATCAAGCGGGCGTGCAA
GCTGGTCGACCGGCTTGTGATTGGCGTTGCGATCAACCGCGACAAGGGGCCTTTGTTCACTCTGGAAGAGCGCGTGGCCC
AGGTGGAGCATGAATGCGCCAAGATGACCGACGCCTTCGGCACCGAGATCATCGCCCACCCGTTCGAGAACCTTCTGATT
GACTGCGCTCGCGATGTTGGCGCACAGACTATTATCCGGGGCCTGCGGGCGGTGGCGGATTTTGAGTACGAGTTTCAGAT
GGTTGGCATGAACCGCAAGCTCGACGATAGCATCACCACCGTGTTTTTGATGGCGGAGGCCGAGCATCAGGCCATCGCGT
CAAAGCTGGTGAAGGAAATCGCGCGATTGGGGGGGGATGTGTCGTCGTTTGTGACGCCGTCCGTCAACACCGCGCTGCGA
GAGAAGTATCCCCGCTGA

Upstream 100 bases:

>100_bases
CATGATCAAGGGCTTCTGAGCACCCGCGCACCGCGATCCGGTTGCAACCGCGGCGTCAATCGTGTTTCCGTCCCACCCGA
GAGAGATGAGGGAGGCCGCG

Downstream 100 bases:

>100_bases
GACCACGCGGGCCGAGATTATGACATATAAGGAGAGCCATCATGGCCGATATCAAAGACCCGGAAAACACGATCCTGATG
GAGCTGAAGGATGGCACCGT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTRTGLYPGTFDPITLGHVDVIKRACKLVDRLVIGVAINRDKGPLFTLEERVAQVEHECAKMTDAFGTEIIAHPFENLLI
DCARDVGAQTIIRGLRAVADFEYEFQMVGMNRKLDDSITTVFLMAEAEHQAIASKLVKEIARLGGDVSSFVTPSVNTALR
EKYPR

Sequences:

>Translated_165_residues
MTRTGLYPGTFDPITLGHVDVIKRACKLVDRLVIGVAINRDKGPLFTLEERVAQVEHECAKMTDAFGTEIIAHPFENLLI
DCARDVGAQTIIRGLRAVADFEYEFQMVGMNRKLDDSITTVFLMAEAEHQAIASKLVKEIARLGGDVSSFVTPSVNTALR
EKYPR
>Mature_164_residues
TRTGLYPGTFDPITLGHVDVIKRACKLVDRLVIGVAINRDKGPLFTLEERVAQVEHECAKMTDAFGTEIIAHPFENLLID
CARDVGAQTIIRGLRAVADFEYEFQMVGMNRKLDDSITTVFLMAEAEHQAIASKLVKEIARLGGDVSSFVTPSVNTALRE
KYPR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=162, Percent_Identity=45.0617283950617, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18308; Mature: 18177

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTGLYPGTFDPITLGHVDVIKRACKLVDRLVIGVAINRDKGPLFTLEERVAQVEHECA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHH
KMTDAFGTEIIAHPFENLLIDCARDVGAQTIIRGLRAVADFEYEFQMVGMNRKLDDSITT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHH
VFLMAEAEHQAIASKLVKEIARLGGDVSSFVTPSVNTALREKYPR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCC
>Mature Secondary Structure 
TRTGLYPGTFDPITLGHVDVIKRACKLVDRLVIGVAINRDKGPLFTLEERVAQVEHECA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHH
KMTDAFGTEIIAHPFENLLIDCARDVGAQTIIRGLRAVADFEYEFQMVGMNRKLDDSITT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHH
VFLMAEAEHQAIASKLVKEIARLGGDVSSFVTPSVNTALREKYPR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA