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The map label for this gene is trkH [H]

Identifier: 89054350

GI number: 89054350

Start: 1846065

End: 1847513

Strand: Direct

Name: trkH [H]

Synonym: Jann_1859

Alternate gene names: 89054350

Gene position: 1846065-1847513 (Clockwise)

Preceding gene: 89054348

Following gene: 89054353

Centisome position: 42.75

GC content: 61.77

Gene sequence:

>1449_bases
ATGTTCGATCTGCGCCCCGTGGGCTACGTCCTTGGCCTTCTGGTCTTCACCCTCGGGGTCACGATGGTGATCCCGCTTGG
TGCGGATGTCTGGGCGGGCAACGGCCATTGGGGCGCGTTCGCGGAGGCGGCGGCCGTCACAATCGTCACCGGGATCTTCC
TGACGCTGGCCTGTGCCAACGGCGTCACCGAGGGGCTGTCGATCCAGCAGACGTTCTTTCTGACCACAGGGGTCTGGCTG
GTGCTGCCTCTGTTCGGGGCCTTGCCGTTCATCTTCGGGGAGCCGGGCGCGCGCGTCGTCGATGCGGTGTTTGAGGCAAT
GTCGGCGATGACCACGACCGGCTCCACCGTCATCACCGACCTCGACAATCTGCCGGTGGGTGTCAATCTGTGGCGGGGCC
TGATGCAGTGGTTCGGTGGCATCGGCATCATTGTGGTCGCCATGGTTTTCCTGCCTGAATTGCGCGTTGGCGGGATGCAG
ATCTTCCGGTCGGAATCCTTTGATACGATGGGGAAAATTCTGCCCCGCGCCGGTGAGATTGCAAGCCGGATCACGGTCAT
TTATCTGGGCCTCACCATCGCCTGTGGTCTGGCCTATCTGGCCGTGGGCATGGCCCCCTTTGACGCTGCGATGCACGCGC
TGACAACGCTGTCGACAGGCGGGTTTTCCAACTACAACGCCTCTTTCGGGGCGTTTCAGGGACCGGCAGAATATGTGGCG
GCGGTGTTCATGATCCTCGCGAGCCTGCCGTTTGTGCGCTACATCCAGCTTGTCGCTGGCACGGCCAAACCGATCCTGGT
CGACACTCAGATCCGCGCCTATCTCGGGATCATCGTGCTGCTGACAATTGTGTTCACGGTCTACCGGCTGGTCGTGTCGG
GCGACAGTATCGAGCATGGGGTGCGGGAGGGTGTCTTCAACGTCACTTCGATCATTTCTGGCACCGGATATTCCAGCACC
AATTATGAGCTTTGGGGACCCGCCGCCCCCGTTATGTTCTTTTTCATCGGCTTGATCGGGGGCTGCGCGGGCTCCACCAG
CTGCTCGATCAAAGTGTTCCGCTACCAACTGTTGTTCGCGTCCATCTCCACCCAGGTGCGCCGCATCTACGCGCCCCACG
GCATATTCGAGCCGAAGTTTGAGGGACGTCCCGTGGCCGAGGAGGTGATCTCCTCCGTCATGGCCTTTTTCGTGCTGTTC
TTTGTGCTTCTGGGCATCATCGCGGTGCTTCTCGGCCTGACGGGGCTGGATGTCGTGACGTCAATCTCAGGTGCGGCCAC
GGCGCTCGGCAATATCGGACCGGGGCTGGGGGACATCATCGGGCCAAGTGGCAACTTTGCCCCCCTCAACGACACGGCGA
AGTGGATCCTGACGGCGGCCATGCTTGTGGGGCGGTTGGAGCTGATGGCGGTGCTGGTGTTGTTCACGGCGACGTTCTGG
CGGGCGTGA

Upstream 100 bases:

>100_bases
CGCAGAGGTCCATCAAATCAATCCTTTAGTGCGCAAATTGGACCGCTGTTGCAGGGGCTCTGCTTGACAGGCAGGGGCGC
GCGCGCCAACCCTCCGCCCT

Downstream 100 bases:

>100_bases
AGCGGGCTCAGGCATGTTGGATCGCGCGGCCCGCCGCAACGCCCGACGACTACGCCCATTGGAAGTTGTATCCCCCCAGC
CAGCCGGTCACGTCCACCGC

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MFDLRPVGYVLGLLVFTLGVTMVIPLGADVWAGNGHWGAFAEAAAVTIVTGIFLTLACANGVTEGLSIQQTFFLTTGVWL
VLPLFGALPFIFGEPGARVVDAVFEAMSAMTTTGSTVITDLDNLPVGVNLWRGLMQWFGGIGIIVVAMVFLPELRVGGMQ
IFRSESFDTMGKILPRAGEIASRITVIYLGLTIACGLAYLAVGMAPFDAAMHALTTLSTGGFSNYNASFGAFQGPAEYVA
AVFMILASLPFVRYIQLVAGTAKPILVDTQIRAYLGIIVLLTIVFTVYRLVVSGDSIEHGVREGVFNVTSIISGTGYSST
NYELWGPAAPVMFFFIGLIGGCAGSTSCSIKVFRYQLLFASISTQVRRIYAPHGIFEPKFEGRPVAEEVISSVMAFFVLF
FVLLGIIAVLLGLTGLDVVTSISGAATALGNIGPGLGDIIGPSGNFAPLNDTAKWILTAAMLVGRLELMAVLVLFTATFW
RA

Sequences:

>Translated_482_residues
MFDLRPVGYVLGLLVFTLGVTMVIPLGADVWAGNGHWGAFAEAAAVTIVTGIFLTLACANGVTEGLSIQQTFFLTTGVWL
VLPLFGALPFIFGEPGARVVDAVFEAMSAMTTTGSTVITDLDNLPVGVNLWRGLMQWFGGIGIIVVAMVFLPELRVGGMQ
IFRSESFDTMGKILPRAGEIASRITVIYLGLTIACGLAYLAVGMAPFDAAMHALTTLSTGGFSNYNASFGAFQGPAEYVA
AVFMILASLPFVRYIQLVAGTAKPILVDTQIRAYLGIIVLLTIVFTVYRLVVSGDSIEHGVREGVFNVTSIISGTGYSST
NYELWGPAAPVMFFFIGLIGGCAGSTSCSIKVFRYQLLFASISTQVRRIYAPHGIFEPKFEGRPVAEEVISSVMAFFVLF
FVLLGIIAVLLGLTGLDVVTSISGAATALGNIGPGLGDIIGPSGNFAPLNDTAKWILTAAMLVGRLELMAVLVLFTATFW
RA
>Mature_482_residues
MFDLRPVGYVLGLLVFTLGVTMVIPLGADVWAGNGHWGAFAEAAAVTIVTGIFLTLACANGVTEGLSIQQTFFLTTGVWL
VLPLFGALPFIFGEPGARVVDAVFEAMSAMTTTGSTVITDLDNLPVGVNLWRGLMQWFGGIGIIVVAMVFLPELRVGGMQ
IFRSESFDTMGKILPRAGEIASRITVIYLGLTIACGLAYLAVGMAPFDAAMHALTTLSTGGFSNYNASFGAFQGPAEYVA
AVFMILASLPFVRYIQLVAGTAKPILVDTQIRAYLGIIVLLTIVFTVYRLVVSGDSIEHGVREGVFNVTSIISGTGYSST
NYELWGPAAPVMFFFIGLIGGCAGSTSCSIKVFRYQLLFASISTQVRRIYAPHGIFEPKFEGRPVAEEVISSVMAFFVLF
FVLLGIIAVLLGLTGLDVVTSISGAATALGNIGPGLGDIIGPSGNFAPLNDTAKWILTAAMLVGRLELMAVLVLFTATFW
RA

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=492, Percent_Identity=35.5691056910569, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1787626, Length=424, Percent_Identity=32.0754716981132, Blast_Score=211, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 51105; Mature: 51105

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDLRPVGYVLGLLVFTLGVTMVIPLGADVWAGNGHWGAFAEAAAVTIVTGIFLTLACAN
CCCCCHHHHHHHHHHHHHHHHHEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GVTEGLSIQQTFFLTTGVWLVLPLFGALPFIFGEPGARVVDAVFEAMSAMTTTGSTVITD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEC
LDNLPVGVNLWRGLMQWFGGIGIIVVAMVFLPELRVGGMQIFRSESFDTMGKILPRAGEI
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHCCHHHH
ASRITVIYLGLTIACGLAYLAVGMAPFDAAMHALTTLSTGGFSNYNASFGAFQGPAEYVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AVFMILASLPFVRYIQLVAGTAKPILVDTQIRAYLGIIVLLTIVFTVYRLVVSGDSIEHG
HHHHHHHHCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VREGVFNVTSIISGTGYSSTNYELWGPAAPVMFFFIGLIGGCAGSTSCSIKVFRYQLLFA
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
SISTQVRRIYAPHGIFEPKFEGRPVAEEVISSVMAFFVLFFVLLGIIAVLLGLTGLDVVT
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SISGAATALGNIGPGLGDIIGPSGNFAPLNDTAKWILTAAMLVGRLELMAVLVLFTATFW
HCCHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RA
CC
>Mature Secondary Structure
MFDLRPVGYVLGLLVFTLGVTMVIPLGADVWAGNGHWGAFAEAAAVTIVTGIFLTLACAN
CCCCCHHHHHHHHHHHHHHHHHEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GVTEGLSIQQTFFLTTGVWLVLPLFGALPFIFGEPGARVVDAVFEAMSAMTTTGSTVITD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEC
LDNLPVGVNLWRGLMQWFGGIGIIVVAMVFLPELRVGGMQIFRSESFDTMGKILPRAGEI
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHCCHHHH
ASRITVIYLGLTIACGLAYLAVGMAPFDAAMHALTTLSTGGFSNYNASFGAFQGPAEYVA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
AVFMILASLPFVRYIQLVAGTAKPILVDTQIRAYLGIIVLLTIVFTVYRLVVSGDSIEHG
HHHHHHHHCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VREGVFNVTSIISGTGYSSTNYELWGPAAPVMFFFIGLIGGCAGSTSCSIKVFRYQLLFA
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
SISTQVRRIYAPHGIFEPKFEGRPVAEEVISSVMAFFVLFFVLLGIIAVLLGLTGLDVVT
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SISGAATALGNIGPGLGDIIGPSGNFAPLNDTAKWILTAAMLVGRLELMAVLVLFTATFW
HCCHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]