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The map label for this gene is grp [H]

Identifier: 89054267

GI number: 89054267

Start: 1764386

End: 1764919

Strand: Direct

Name: grp [H]

Synonym: Jann_1776

Alternate gene names: 89054267

Gene position: 1764386-1764919 (Clockwise)

Preceding gene: 89054260

Following gene: 89054269

Centisome position: 40.86

GC content: 56.74

Gene sequence:

>534_bases
ATGTTCTGTATCCCGCTCAGGTCAGAACCCATGTCCGCAAATCCAAAGGTCCCCCGAATGCCTGTTCAGATCGACGCCCT
CGACCGGAAAATCCTCATCGCGTTGCAGGAGGATGCAAGCCGGTCTTTGGAGGATATCGCCAAACATGTGGGGTCGTCCA
AGACGCCCGTCTGGTCGCGGATTCGCAAGATGAAAGAGGCCGGGATCATCGGCCAGCAAACAGTACTTCTGGATGCGGAA
GCTTTGGGGCTAGAGGCTTGTTTTTTCGTCCTGATCCGCACGTCCGAGCATGAGGCGGAGTGGCAAAACAGGTTCCTGAA
AACTCTGCGCGAGCGGGCAGAGGTGATGGAGGCGCACCGCCTTGCGGGCGACATCGATTACATCCTGAAAGTGCGTGTCG
CCAACGCGCGGGCCTATGACGAATTTTACCAGGCCCTGATCTCAGAAGTGCGGATCTACAACGTCACCGCCCTTCTGAGC
ATGGAAGAGATCAAATCGACGCCGCTTTTGCCGCTTGGGTCAGTTCCGTCTTGA

Upstream 100 bases:

>100_bases
TGGAAAATGGCGCATGGGATGGAACCTCGCTTGCTGAATGCCCCCTCAAGATAGGATATTTTCCCGATAAATGGCAGGTG
AGGCTTGCTGAAAGGGACGC

Downstream 100 bases:

>100_bases
TCCTCGCCCCCGCCTCCAGCGACCGGTGGACGGGGCATTTATCGGCAATCTCTAACAGGCGCGCGCGCTGATCGTCGTCC
AGCGCCCCCGTCAATGTGAT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MFCIPLRSEPMSANPKVPRMPVQIDALDRKILIALQEDASRSLEDIAKHVGSSKTPVWSRIRKMKEAGIIGQQTVLLDAE
ALGLEACFFVLIRTSEHEAEWQNRFLKTLRERAEVMEAHRLAGDIDYILKVRVANARAYDEFYQALISEVRIYNVTALLS
MEEIKSTPLLPLGSVPS

Sequences:

>Translated_177_residues
MFCIPLRSEPMSANPKVPRMPVQIDALDRKILIALQEDASRSLEDIAKHVGSSKTPVWSRIRKMKEAGIIGQQTVLLDAE
ALGLEACFFVLIRTSEHEAEWQNRFLKTLRERAEVMEAHRLAGDIDYILKVRVANARAYDEFYQALISEVRIYNVTALLS
MEEIKSTPLLPLGSVPS
>Mature_177_residues
MFCIPLRSEPMSANPKVPRMPVQIDALDRKILIALQEDASRSLEDIAKHVGSSKTPVWSRIRKMKEAGIIGQQTVLLDAE
ALGLEACFFVLIRTSEHEAEWQNRFLKTLRERAEVMEAHRLAGDIDYILKVRVANARAYDEFYQALISEVRIYNVTALLS
MEEIKSTPLLPLGSVPS

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=40.6666666666667, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1787116, Length=145, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 20008; Mature: 20008

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCIPLRSEPMSANPKVPRMPVQIDALDRKILIALQEDASRSLEDIAKHVGSSKTPVWSR
CEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHCCHHHHHHHCCCCCCHHHHH
IRKMKEAGIIGQQTVLLDAEALGLEACFFVLIRTSEHEAEWQNRFLKTLRERAEVMEAHR
HHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAGDIDYILKVRVANARAYDEFYQALISEVRIYNVTALLSMEEIKSTPLLPLGSVPS
HHCCHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFCIPLRSEPMSANPKVPRMPVQIDALDRKILIALQEDASRSLEDIAKHVGSSKTPVWSR
CEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHCCHHHHHHHCCCCCCHHHHH
IRKMKEAGIIGQQTVLLDAEALGLEACFFVLIRTSEHEAEWQNRFLKTLRERAEVMEAHR
HHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAGDIDYILKVRVANARAYDEFYQALISEVRIYNVTALLSMEEIKSTPLLPLGSVPS
HHCCHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]