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The map label for this gene is coxS [H]

Identifier: 89054254

GI number: 89054254

Start: 1752072

End: 1752557

Strand: Direct

Name: coxS [H]

Synonym: Jann_1763

Alternate gene names: 89054254

Gene position: 1752072-1752557 (Clockwise)

Preceding gene: 89054253

Following gene: 89054255

Centisome position: 40.58

GC content: 62.76

Gene sequence:

>486_bases
ATGACCCAGGTATCGATGACGGTAAACGGCAAGGCCGTTTCCGGCGACGTCGAAGGGCGCACGCTGCTGAGCGAATTTCT
ACGCGAAGGCCAACGGCTGACCGGCACCCATGTGGGCTGCGACACCAGCCAATGCGGCGCTTGTGTCGTCCATGTGAACG
GCGAGGCGGTCAAAAGCTGCACCACGCTGGCGCTGGATATCGACGGCGCGGAGGTCAAGACGATTGAGGGCATGGCCAAT
GCCGACGGCTCTTTGGGCGTGATCCAGCAGGCATTTCAGGACCACCATGGCCTGCAATGCGGCTTCTGCACGCCGGGCAT
GGTGATGTCGGCGGCGGCGCTTTTGAAGGACAACCCGAAACCGTCGGAGGCCGAGGTGCGCGAGTATCTTGAAGGCAATA
TTTGCCGCTGCACGGGCTACCACAACATCGTCAAGGCGATCATGGCCGCGTCGGGCCAGGATGTGGCCCCGATGGCGGCG
GAGTAG

Upstream 100 bases:

>100_bases
AATGCGCCCAAACGCCGCCTGTGCGGTATTGCCATGAAGTAAGGCTTTGTCTTTCACAGATTTCGTGCTTGGATGAAAAA
AACACCCAAGGGAGGATTTC

Downstream 100 bases:

>100_bases
CGATGGCCGACTTCGTGGAAATCGGAAGCGATGATCCCACGGCCACGAAAGCGTTCTTTGCGGATGTCTTCGGGTGGCAG
TGGGAGGCGTTCGGCGACGG

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTQVSMTVNGKAVSGDVEGRTLLSEFLREGQRLTGTHVGCDTSQCGACVVHVNGEAVKSCTTLALDIDGAEVKTIEGMAN
ADGSLGVIQQAFQDHHGLQCGFCTPGMVMSAAALLKDNPKPSEAEVREYLEGNICRCTGYHNIVKAIMAASGQDVAPMAA
E

Sequences:

>Translated_161_residues
MTQVSMTVNGKAVSGDVEGRTLLSEFLREGQRLTGTHVGCDTSQCGACVVHVNGEAVKSCTTLALDIDGAEVKTIEGMAN
ADGSLGVIQQAFQDHHGLQCGFCTPGMVMSAAALLKDNPKPSEAEVREYLEGNICRCTGYHNIVKAIMAASGQDVAPMAA
E
>Mature_160_residues
TQVSMTVNGKAVSGDVEGRTLLSEFLREGQRLTGTHVGCDTSQCGACVVHVNGEAVKSCTTLALDIDGAEVKTIEGMANA
DGSLGVIQQAFQDHHGLQCGFCTPGMVMSAAALLKDNPKPSEAEVREYLEGNICRCTGYHNIVKAIMAASGQDVAPMAAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=156, Percent_Identity=34.6153846153846, Blast_Score=90, Evalue=8e-19,
Organism=Homo sapiens, GI91823271, Length=159, Percent_Identity=31.4465408805031, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=43.030303030303, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=43.5374149659864, Blast_Score=113, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=158, Percent_Identity=39.873417721519, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32566215, Length=164, Percent_Identity=34.1463414634146, Blast_Score=99, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=159, Percent_Identity=33.9622641509434, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737937, Length=151, Percent_Identity=43.046357615894, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24647193, Length=154, Percent_Identity=39.6103896103896, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647199, Length=130, Percent_Identity=40.7692307692308, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647197, Length=158, Percent_Identity=35.4430379746835, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647195, Length=158, Percent_Identity=35.4430379746835, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647201, Length=151, Percent_Identity=35.0993377483444, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16817; Mature: 16686

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
8.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVSMTVNGKAVSGDVEGRTLLSEFLREGQRLTGTHVGCDTSQCGACVVHVNGEAVKSC
CCEEEEEECCEEEECCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEECCHHHHCE
TTLALDIDGAEVKTIEGMANADGSLGVIQQAFQDHHGLQCGFCTPGMVMSAAALLKDNPK
EEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHCCCCC
PSEAEVREYLEGNICRCTGYHNIVKAIMAASGQDVAPMAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TQVSMTVNGKAVSGDVEGRTLLSEFLREGQRLTGTHVGCDTSQCGACVVHVNGEAVKSC
CEEEEEECCEEEECCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEECCHHHHCE
TTLALDIDGAEVKTIEGMANADGSLGVIQQAFQDHHGLQCGFCTPGMVMSAAALLKDNPK
EEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHCCCCC
PSEAEVREYLEGNICRCTGYHNIVKAIMAASGQDVAPMAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]