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The map label for this gene is dgoD1 [H]

Identifier: 89054156

GI number: 89054156

Start: 1649217

End: 1650437

Strand: Direct

Name: dgoD1 [H]

Synonym: Jann_1665

Alternate gene names: 89054156

Gene position: 1649217-1650437 (Clockwise)

Preceding gene: 89054155

Following gene: 89054160

Centisome position: 38.19

GC content: 65.6

Gene sequence:

>1221_bases
ATGAAACTCGACACTTTGGACATCTTCGCCGTCGCTCCCCCGCCCCCCGGCTGGGGCGGGCGCTATTGGCTGCTCGTCCG
CGTCACTACCGACACCGGCCTCACGGGCCTGGGTGAAGTCTATGCCGCGGGCGTCGGGCCGGAGGCGATGACACATGTCA
TCCACGACGTCTTCACCCGCCACATGCGCGGTGAAGACCCGGCCAATATCGAACTGATGTCGCGCCGGGCCCACTCCTCC
GGCTTCACGCAGCGCCCTGATCCCACGGTGTTCGGCGCGTTCTCAGGCCTTGAAATGGCCTGCTGGGATATCCTCGGCAA
GGCGCGGGATTGCCCGGTCTGGGCGATGCTCGGCGGCAAGATGAACGACCGCATCCGCGCCTACACCTACCTCTATCCCG
AACCTCACCACGACACGAACGCCTTCTGGACATCGCCCGAAATGGCCGCGGAAAGCGCCGCCGCCCGTGTGGCGGAAGGG
TACACAGCGGTGAAATTCGACCCCGCTGGCCCCTACACAATGCGCGGGGGCCATATGCCCGCGCTCAGCGACATTGACCT
GTCGGCGCGGTTTTGTGCGGCGATCCGGGACGCGGTGGGCACCCAGGCTGACCTCCTTTTCGGCACCCATGGTCAGTTTG
CGCCTGCTGGCGCGATCCGCCTTGCCAAGGCCATCGAGCCCTATGATCCGCTTTGGTATGAAGAGCCCATTCCGCCCGAT
AACCTCCCCGGTCTGTCCGAGGTCGCGGCCCATACCTCGATCCCCATCGCCACCGGCGAACGGCTGACGGGCGTGACCGA
ATTCACCCAAGCGCTGCACCACGGCGCGCGGATCCTGCAACCGGCCCTTGGGCGCGCGGGCGGGATATGGGAGGGCAAGA
AAATCGCCACCCTGGCCGCCGCCTTTGGCGCGCAGCTGGCCCCGCACCTTTACGCCGGTCCTGTCGAATGGGCCGCGAAT
GTGCATCTGGGCGTAAGTTGTCCGAACCTGTTGATGGTGGAGGCGATTGAGACGCCTTTCCACGAGGCCCTCGTCACCGG
ACGGCCCAGGGTGGAAAACGGCTTCGTTGCAGCTCCCGACGCGCCGGGGCTTGGCATCACACTGAACGACGCGATCGCAA
ACGCGCATCGCTACACCGGGAACCGGCTGCATCTGGAGATGCAGGACGCACCGTGCGATTGGCAGAACGGAAATTCCTTC
GGCGGCGGAGCCGTCGACTAA

Upstream 100 bases:

>100_bases
CGCAACGTCATCACCTTCTAGTCCGCCGCTCGGCCCCTCCTTCCCTGTTCCATAAATATCCCGGGGGTGTGGGGGCTGGC
CCCCACGAGGTGCACCATTC

Downstream 100 bases:

>100_bases
TGGCCCGCAGGGCCATACCCGCGCCGAAGGCGCGTTTAGCCCCCGCCGGAGGCGCGGTTGCCGGACCTGCCTGGCGTTAC
CGCTCGCGCTCATGGGCATA

Product: mandelate racemase/muconate lactonizing enzyme

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKLDTLDIFAVAPPPPGWGGRYWLLVRVTTDTGLTGLGEVYAAGVGPEAMTHVIHDVFTRHMRGEDPANIELMSRRAHSS
GFTQRPDPTVFGAFSGLEMACWDILGKARDCPVWAMLGGKMNDRIRAYTYLYPEPHHDTNAFWTSPEMAAESAAARVAEG
YTAVKFDPAGPYTMRGGHMPALSDIDLSARFCAAIRDAVGTQADLLFGTHGQFAPAGAIRLAKAIEPYDPLWYEEPIPPD
NLPGLSEVAAHTSIPIATGERLTGVTEFTQALHHGARILQPALGRAGGIWEGKKIATLAAAFGAQLAPHLYAGPVEWAAN
VHLGVSCPNLLMVEAIETPFHEALVTGRPRVENGFVAAPDAPGLGITLNDAIANAHRYTGNRLHLEMQDAPCDWQNGNSF
GGGAVD

Sequences:

>Translated_406_residues
MKLDTLDIFAVAPPPPGWGGRYWLLVRVTTDTGLTGLGEVYAAGVGPEAMTHVIHDVFTRHMRGEDPANIELMSRRAHSS
GFTQRPDPTVFGAFSGLEMACWDILGKARDCPVWAMLGGKMNDRIRAYTYLYPEPHHDTNAFWTSPEMAAESAAARVAEG
YTAVKFDPAGPYTMRGGHMPALSDIDLSARFCAAIRDAVGTQADLLFGTHGQFAPAGAIRLAKAIEPYDPLWYEEPIPPD
NLPGLSEVAAHTSIPIATGERLTGVTEFTQALHHGARILQPALGRAGGIWEGKKIATLAAAFGAQLAPHLYAGPVEWAAN
VHLGVSCPNLLMVEAIETPFHEALVTGRPRVENGFVAAPDAPGLGITLNDAIANAHRYTGNRLHLEMQDAPCDWQNGNSF
GGGAVD
>Mature_406_residues
MKLDTLDIFAVAPPPPGWGGRYWLLVRVTTDTGLTGLGEVYAAGVGPEAMTHVIHDVFTRHMRGEDPANIELMSRRAHSS
GFTQRPDPTVFGAFSGLEMACWDILGKARDCPVWAMLGGKMNDRIRAYTYLYPEPHHDTNAFWTSPEMAAESAAARVAEG
YTAVKFDPAGPYTMRGGHMPALSDIDLSARFCAAIRDAVGTQADLLFGTHGQFAPAGAIRLAKAIEPYDPLWYEEPIPPD
NLPGLSEVAAHTSIPIATGERLTGVTEFTQALHHGARILQPALGRAGGIWEGKKIATLAAAFGAQLAPHLYAGPVEWAAN
VHLGVSCPNLLMVEAIETPFHEALVTGRPRVENGFVAAPDAPGLGITLNDAIANAHRYTGNRLHLEMQDAPCDWQNGNSF
GGGAVD

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=389, Percent_Identity=29.5629820051414, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787864, Length=406, Percent_Identity=25.615763546798, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI226510960, Length=355, Percent_Identity=23.943661971831, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 43504; Mature: 43504

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDTLDIFAVAPPPPGWGGRYWLLVRVTTDTGLTGLGEVYAAGVGPEAMTHVIHDVFTR
CCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
HMRGEDPANIELMSRRAHSSGFTQRPDPTVFGAFSGLEMACWDILGKARDCPVWAMLGGK
HHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCC
MNDRIRAYTYLYPEPHHDTNAFWTSPEMAAESAAARVAEGYTAVKFDPAGPYTMRGGHMP
CCCCEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCC
ALSDIDLSARFCAAIRDAVGTQADLLFGTHGQFAPAGAIRLAKAIEPYDPLWYEEPIPPD
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
NLPGLSEVAAHTSIPIATGERLTGVTEFTQALHHGARILQPALGRAGGIWEGKKIATLAA
CCCCHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AFGAQLAPHLYAGPVEWAANVHLGVSCPNLLMVEAIETPFHEALVTGRPRVENGFVAAPD
HHHHHHCCHHCCCCHHHCCEEEEECCCCCCEEHHHHHCCHHHHHHCCCCCCCCCEEECCC
APGLGITLNDAIANAHRYTGNRLHLEMQDAPCDWQNGNSFGGGAVD
CCCCEEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLDTLDIFAVAPPPPGWGGRYWLLVRVTTDTGLTGLGEVYAAGVGPEAMTHVIHDVFTR
CCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
HMRGEDPANIELMSRRAHSSGFTQRPDPTVFGAFSGLEMACWDILGKARDCPVWAMLGGK
HHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCC
MNDRIRAYTYLYPEPHHDTNAFWTSPEMAAESAAARVAEGYTAVKFDPAGPYTMRGGHMP
CCCCEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCC
ALSDIDLSARFCAAIRDAVGTQADLLFGTHGQFAPAGAIRLAKAIEPYDPLWYEEPIPPD
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
NLPGLSEVAAHTSIPIATGERLTGVTEFTQALHHGARILQPALGRAGGIWEGKKIATLAA
CCCCHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AFGAQLAPHLYAGPVEWAANVHLGVSCPNLLMVEAIETPFHEALVTGRPRVENGFVAAPD
HHHHHHCCHHCCCCHHHCCEEEEECCCCCCEEHHHHHCCHHHHHHCCCCCCCCCEEECCC
APGLGITLNDAIANAHRYTGNRLHLEMQDAPCDWQNGNSFGGGAVD
CCCCEEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA