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The map label for this gene is fabA [H]

Identifier: 89054144

GI number: 89054144

Start: 1638081

End: 1638590

Strand: Direct

Name: fabA [H]

Synonym: Jann_1653

Alternate gene names: 89054144

Gene position: 1638081-1638590 (Clockwise)

Preceding gene: 89054139

Following gene: 89054145

Centisome position: 37.94

GC content: 62.94

Gene sequence:

>510_bases
ATGTCCGATTATCCGACAAGCTTTGACCGCGAAGATCTGCTGCGCTGCGCGCGCGGAGAGCTGTTTGGCGAGGGCAATGC
GCAACTTCCCGAACCGCCGATGCTGATGATGGACCGGATCACCGACATCTCGGGCGATGGTGGAGAGCACGGCAAGGGTC
ACGTGCGCGCCGAGTTCGACATCACGCCGGAGGCCTGGTTTTTCGACTGCCATTTCCCCGGCAATCCGATCATGCCCGGG
TGTCTGGGCCTGGATGGCTTGTGGCAGCTGACCGGATTCAACCTGGGCTGGCGCGGCTGGCAGGGGCGCGGCTATGCGCT
GGGTGTGGGCGAGGTGAAGCTGACTGGCATGGTGCGCCCGGACCGCAAGATGCTGACCTATTACGTGGATTTCACCAAGG
CGATCCAGACCCGCCGCCTGACGATGGGCGTGGCCGATGGCCGGGTGGAGGCCGATGGTGAGGTCATCTATATGGTCAAG
GACATGAAGGTCGCGCTGAGCGAAAGCTGA

Upstream 100 bases:

>100_bases
GCCAAGCCCGACCCGGCCCCGCCCTTGCGCGCGAATTGACGTGGGTGCTAGGTGTGGCCAAGCCGCAAACGGCGCAAAAC
AAGACGAGCAAGGGGGCCCA

Downstream 100 bases:

>100_bases
GCCCGCCGAGGAAGCGCGGGAGCAGCGCCATGACCATAGATCGCCATCCAGACGGCTTGATCGGTAAATGCAGTGCGGCC
GTCCATGGTGGTCTGGCCTA

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSDYPTSFDREDLLRCARGELFGEGNAQLPEPPMLMMDRITDISGDGGEHGKGHVRAEFDITPEAWFFDCHFPGNPIMPG
CLGLDGLWQLTGFNLGWRGWQGRGYALGVGEVKLTGMVRPDRKMLTYYVDFTKAIQTRRLTMGVADGRVEADGEVIYMVK
DMKVALSES

Sequences:

>Translated_169_residues
MSDYPTSFDREDLLRCARGELFGEGNAQLPEPPMLMMDRITDISGDGGEHGKGHVRAEFDITPEAWFFDCHFPGNPIMPG
CLGLDGLWQLTGFNLGWRGWQGRGYALGVGEVKLTGMVRPDRKMLTYYVDFTKAIQTRRLTMGVADGRVEADGEVIYMVK
DMKVALSES
>Mature_168_residues
SDYPTSFDREDLLRCARGELFGEGNAQLPEPPMLMMDRITDISGDGGEHGKGHVRAEFDITPEAWFFDCHFPGNPIMPGC
LGLDGLWQLTGFNLGWRGWQGRGYALGVGEVKLTGMVRPDRKMLTYYVDFTKAIQTRRLTMGVADGRVEADGEVIYMVKD
MKVALSES

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=168, Percent_Identity=56.547619047619, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18858; Mature: 18727

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYPTSFDREDLLRCARGELFGEGNAQLPEPPMLMMDRITDISGDGGEHGKGHVRAEFD
CCCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEE
ITPEAWFFDCHFPGNPIMPGCLGLDGLWQLTGFNLGWRGWQGRGYALGVGEVKLTGMVRP
CCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEECCEEEEEEECC
DRKMLTYYVDFTKAIQTRRLTMGVADGRVEADGEVIYMVKDMKVALSES
CCEEEEEEEEHHHHHHHHEEEEEECCCEEECCCCEEEEEECEEEEECCC
>Mature Secondary Structure 
SDYPTSFDREDLLRCARGELFGEGNAQLPEPPMLMMDRITDISGDGGEHGKGHVRAEFD
CCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEE
ITPEAWFFDCHFPGNPIMPGCLGLDGLWQLTGFNLGWRGWQGRGYALGVGEVKLTGMVRP
CCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEECCEEEEEEECC
DRKMLTYYVDFTKAIQTRRLTMGVADGRVEADGEVIYMVKDMKVALSES
CCEEEEEEEEHHHHHHHHEEEEEECCCEEECCCCEEEEEECEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA