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The map label for this gene is mmuM [H]

Identifier: 89054089

GI number: 89054089

Start: 1581532

End: 1582425

Strand: Direct

Name: mmuM [H]

Synonym: Jann_1598

Alternate gene names: 89054089

Gene position: 1581532-1582425 (Clockwise)

Preceding gene: 89054088

Following gene: 89054090

Centisome position: 36.63

GC content: 66.22

Gene sequence:

>894_bases
ATGACCGAGATTACGATCCTTGATGGTGGCATGGGGCAGGAACTTGTGTCGCGCTCCGACGTGCCGCCGACCCCGTTGTG
GTCCACCGATGTGATGCGCGCCAAGCCGCATCTGGTGGGCGAGGTTCACCGCGATTTCTTCAACGCAGGCGCGCAGATCG
CCACCGCCAACACCTATGCGATCCACCGCGACCGTCTTGTGCGCGCGGATGCGGAGGCCGAGTTCGCCAGCCTGCACAAA
ACCGCGCTGGATCAGGCGCGTCAGGCCCGCGATGCCCATGGGTCCGGTCTTGTGGCAGGCGCCATCGGGCCCCTCGGCGC
GTCCTACCGGCCTGATCTGACACCCCAGCACAGCGCCGCCGTGGCGCTCTATGCCGAGATCGCGACGCTTCACGCGCCCC
TTGTTGATCTGTTGATTTGTGAGACGATCACCTCGCTGGCCCAGGCGGAGGCGGTTCTGGATGCCTGCCTTGGCCACGGC
GTGCCGGTTTGGCTGGCCTTCAGCGTGGATGACAGGGATGGCACGCGGCTGCGCTCGGGCGAAGGCTTGGGCGATGTCAT
TGCCATGGCGGGTGAGGCGGCGGCGCTTCTGGCCAATTGTTCCGTGCCGGAGGTGATGCCCGCGGCCCTCGACATTCTGG
GTCGGGCGGGCACGCCGTTTGGGGCCTATGCCAATGGCTTCACCGAGATCAGCGCCGGGTTTCTGGATGATGCCCCCACC
GTCGATGCCCTGACCAGCCGCACCGATATGGGGCCTGAAGCCTATGCCGATCACGTCATGGGCTGGATCGACCAGGGGGC
CACCATCGTTGGCGGCTGTTGTGAAGTCGGCCCCGCGCATATCGCGGAAATCACGCGCCGGGTGACCGCCTTGGGCGGGA
AGGGGCCATCATGA

Upstream 100 bases:

>100_bases
AGGCGCTGCAAGGGGTCTGGCTCAACCGCATCTCCGGCGGGTTGATGCTGGCCGCTGCCGTGTTACTCGGCTCCCGCGAT
TTGAGCGTGGAGGCGAGACA

Downstream 100 bases:

>100_bases
CGGGCCTCAAGCGTCCTCTCAGACCACCTGACTGGTCCGATACCCATGCGGCGCCCCTGCGCGCCGAGCTGACAACGGCG
CGCGCGGCCTACGAGGTGGC

Product: homocysteine S-methyltransferase

Products: NA

Alternate protein names: S-methylmethionine:homocysteine methyltransferase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTEITILDGGMGQELVSRSDVPPTPLWSTDVMRAKPHLVGEVHRDFFNAGAQIATANTYAIHRDRLVRADAEAEFASLHK
TALDQARQARDAHGSGLVAGAIGPLGASYRPDLTPQHSAAVALYAEIATLHAPLVDLLICETITSLAQAEAVLDACLGHG
VPVWLAFSVDDRDGTRLRSGEGLGDVIAMAGEAAALLANCSVPEVMPAALDILGRAGTPFGAYANGFTEISAGFLDDAPT
VDALTSRTDMGPEAYADHVMGWIDQGATIVGGCCEVGPAHIAEITRRVTALGGKGPS

Sequences:

>Translated_297_residues
MTEITILDGGMGQELVSRSDVPPTPLWSTDVMRAKPHLVGEVHRDFFNAGAQIATANTYAIHRDRLVRADAEAEFASLHK
TALDQARQARDAHGSGLVAGAIGPLGASYRPDLTPQHSAAVALYAEIATLHAPLVDLLICETITSLAQAEAVLDACLGHG
VPVWLAFSVDDRDGTRLRSGEGLGDVIAMAGEAAALLANCSVPEVMPAALDILGRAGTPFGAYANGFTEISAGFLDDAPT
VDALTSRTDMGPEAYADHVMGWIDQGATIVGGCCEVGPAHIAEITRRVTALGGKGPS
>Mature_296_residues
TEITILDGGMGQELVSRSDVPPTPLWSTDVMRAKPHLVGEVHRDFFNAGAQIATANTYAIHRDRLVRADAEAEFASLHKT
ALDQARQARDAHGSGLVAGAIGPLGASYRPDLTPQHSAAVALYAEIATLHAPLVDLLICETITSLAQAEAVLDACLGHGV
PVWLAFSVDDRDGTRLRSGEGLGDVIAMAGEAAALLANCSVPEVMPAALDILGRAGTPFGAYANGFTEISAGFLDDAPTV
DALTSRTDMGPEAYADHVMGWIDQGATIVGGCCEVGPAHIAEITRRVTALGGKGPS

Specific function: Catalyzes methyl transfer from S-methylmethionine or S- adenosylmethionine (less efficient) to homocysteine, selenohomocysteine and less efficiently selenocysteine [H]

COG id: COG2040

COG function: function code E; Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Hcy-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786456, Length=315, Percent_Identity=31.7460317460317, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003726 [H]

Pfam domain/function: PF02574 S-methyl_trans [H]

EC number: =2.1.1.10 [H]

Molecular weight: Translated: 30857; Mature: 30726

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50970 HCY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEITILDGGMGQELVSRSDVPPTPLWSTDVMRAKPHLVGEVHRDFFNAGAQIATANTYA
CCEEEEEECCCCHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCEEEECCEEE
IHRDRLVRADAEAEFASLHKTALDQARQARDAHGSGLVAGAIGPLGASYRPDLTPQHSAA
EHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHH
VALYAEIATLHAPLVDLLICETITSLAQAEAVLDACLGHGVPVWLAFSVDDRDGTRLRSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEECCC
EGLGDVIAMAGEAAALLANCSVPEVMPAALDILGRAGTPFGAYANGFTEISAGFLDDAPT
CCHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCCCCCCCC
VDALTSRTDMGPEAYADHVMGWIDQGATIVGGCCEVGPAHIAEITRRVTALGGKGPS
HHHHHHCCCCCHHHHHHHHHHHHHCCCEEECHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEITILDGGMGQELVSRSDVPPTPLWSTDVMRAKPHLVGEVHRDFFNAGAQIATANTYA
CEEEEEECCCCHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCEEEECCEEE
IHRDRLVRADAEAEFASLHKTALDQARQARDAHGSGLVAGAIGPLGASYRPDLTPQHSAA
EHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHH
VALYAEIATLHAPLVDLLICETITSLAQAEAVLDACLGHGVPVWLAFSVDDRDGTRLRSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEECCC
EGLGDVIAMAGEAAALLANCSVPEVMPAALDILGRAGTPFGAYANGFTEISAGFLDDAPT
CCHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCCCCCCCC
VDALTSRTDMGPEAYADHVMGWIDQGATIVGGCCEVGPAHIAEITRRVTALGGKGPS
HHHHHHCCCCCHHHHHHHHHHHHHCCCEEECHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9882684; 10026151 [H]