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The map label for this gene is betT [C]

Identifier: 89054084

GI number: 89054084

Start: 1574118

End: 1575923

Strand: Reverse

Name: betT [C]

Synonym: Jann_1593

Alternate gene names: 89054084

Gene position: 1575923-1574118 (Counterclockwise)

Preceding gene: 89054086

Following gene: 89054083

Centisome position: 36.5

GC content: 60.74

Gene sequence:

>1806_bases
ATGCGCCATGCAGGCCTGTGGCTGCGGATACGCAATACGGGAGACATCACCATGGCGATCGAGCCACCCATCACAGACCT
CGATATCCCGACAGCCGATTCCGGTTTCTACAAGGGATTTACAAAGATCGTCGCACTGACAGGGAAATTCCTGGTCGCCG
TGCTGATCATATGGGCGCTGCTGCCGGCAGCATCGCTGACGTTCGGGCCCGCGGCAGAGGGCTCCACCTCGCTCTTCATC
GACGCGGACGGCAATGTCTCCGCTGCGGCGGGCGTCGTGCTTGGCGGGATCAATTCGCTGATTCTGGCGACATTCAATTA
CTGGTACGTCTACGTCATGGCGTTCTTCGTGATCCTATGCATCATCCTGGCGCTTTGGCCCGCCTCGGGCCGCCTGAAGA
TGGGACTGGATGACGACAAACCAGAATTCACCAACTTCTCCTGGTTTTCGATGATGTTTGGCGCCGGGATCGGGATCGGG
ATGCTGACCTTTGCCACGGCAGAGCCGATGTATCACTGGGGCTCCAACCCGTCGACCATTCAGGGTATCACCGAAGGCTC
CACCGCCGGAAACGTGCGCGACGCCTATATCTGGTCCTTCACCCACTGGGGTCTGGCCGCATGGGCCTCCTACGCCATTG
TCGGTCTGGCGCTTGGCTACTTCGCGTACCGCCGCAGTCTGCCGCTGACGATCCGCTCGGCGCTGGTGCCGATCTTCGGC
AAGTCGATGGAGGGTGGTCTGGGCCACGCCGTGGACATCGTGGCCGTTGTGGCGACAGTTCTGGGCGTGTCGCAGACACT
CGGTTTCGGGGTGGAGCAATTCATCTCGGGCCTCACCCGGATCGGGGTGGGCGATTGGCTACAGCAAACCGCTGAAGATG
GCTCGGTTTCGGCCTCGACCGCCGGTATCATCGTGGCCCTGATGGTCATCATGGGCGCCTCGACCCTGTCTGCGCTGTCC
GGCGTGGGCAAAGGCATCAAATGGCTGTCCAACATCAATATGGGCCTCAGCTTCTTTATCCTGCTGTTCTTCCTGGCCTT
TGGCTCCACCTTCTTTGGGCTTCAGGCCCTGGTCGTGGGCATCTTCGACTACCTCATCTCAATACCCGGCAATATCTTCA
CCGTCTGGGTCTCCGATGGCGTCGATGGGTCAGAGGCCGCGGGCCTTGCCGGTTGGCAAGGTGGCTGGACCATCTTCTAC
TGGGCCTGGTGGATCGCATTCGCGCCCTTCGTGGGCGTGTTCCTGGCGCGGATCTCAAAGGGTCGCACGGTGCGGGAATA
TGTGTTGGGCGCAATGATCGTGCCTGCCATCATGTGCTTCACCTGGTTTGCCATCGTGGGCGGCACGGCCATTGATCTGG
AGCTGAATGGCGGCGCAGGCGGCGCGATCCAGGACGCTGGTCAATCCGACCAGCTCTTCGCGATGCTGGCCGTGATGCTC
AGCGACAACCTCGCGTGGATCATGTCGGTCATCGTGGTGATCCTGCTGCTGACCTACCTCGTGACCTCGGCCGACTCGGC
GGTTCTGATCATCAACACGATCAACGCCGCTGGTGACGAAGGCCCAAAGGCCCGGCCTCACATCATCTTCTGGGGTGCCG
CGCTGGCGCTTGTCGTAGGTGGTTTGATCATCGCCGGTGGTCTTGGGGCCATTCAGGCCGCGATGGTGATCGGTGCCCTG
CCCTTCAGCCTTGTCATGGTGCTTATGGGTCTGGCGTTGATCAAGGCAATCATCAACGATTCCCGCCGTGAAAAGCAGGG
CGTCGCCACCACCCATGATGAGATTGACACCGTCCCTGCCGAGTAA

Upstream 100 bases:

>100_bases
TCCGCACATGTAAGATTGCTTTTGTAAATGTAAGAATCGCGCTTAGTGTGCGGGCATACGCAAGAATGCCTCGAAAATGA
GGCGGTGATCCGCAAGAAAC

Downstream 100 bases:

>100_bases
CCTCGTCACATGCTAAACCAGACGGGCCGCACCTCATCGTGCGGCCCGTTTTTTCTTGTCAGGACCGGAGGTCGCAATGG
ACGATTTTTTCAAACTGGGA

Product: BCCT transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MRHAGLWLRIRNTGDITMAIEPPITDLDIPTADSGFYKGFTKIVALTGKFLVAVLIIWALLPAASLTFGPAAEGSTSLFI
DADGNVSAAAGVVLGGINSLILATFNYWYVYVMAFFVILCIILALWPASGRLKMGLDDDKPEFTNFSWFSMMFGAGIGIG
MLTFATAEPMYHWGSNPSTIQGITEGSTAGNVRDAYIWSFTHWGLAAWASYAIVGLALGYFAYRRSLPLTIRSALVPIFG
KSMEGGLGHAVDIVAVVATVLGVSQTLGFGVEQFISGLTRIGVGDWLQQTAEDGSVSASTAGIIVALMVIMGASTLSALS
GVGKGIKWLSNINMGLSFFILLFFLAFGSTFFGLQALVVGIFDYLISIPGNIFTVWVSDGVDGSEAAGLAGWQGGWTIFY
WAWWIAFAPFVGVFLARISKGRTVREYVLGAMIVPAIMCFTWFAIVGGTAIDLELNGGAGGAIQDAGQSDQLFAMLAVML
SDNLAWIMSVIVVILLLTYLVTSADSAVLIINTINAAGDEGPKARPHIIFWGAALALVVGGLIIAGGLGAIQAAMVIGAL
PFSLVMVLMGLALIKAIINDSRREKQGVATTHDEIDTVPAE

Sequences:

>Translated_601_residues
MRHAGLWLRIRNTGDITMAIEPPITDLDIPTADSGFYKGFTKIVALTGKFLVAVLIIWALLPAASLTFGPAAEGSTSLFI
DADGNVSAAAGVVLGGINSLILATFNYWYVYVMAFFVILCIILALWPASGRLKMGLDDDKPEFTNFSWFSMMFGAGIGIG
MLTFATAEPMYHWGSNPSTIQGITEGSTAGNVRDAYIWSFTHWGLAAWASYAIVGLALGYFAYRRSLPLTIRSALVPIFG
KSMEGGLGHAVDIVAVVATVLGVSQTLGFGVEQFISGLTRIGVGDWLQQTAEDGSVSASTAGIIVALMVIMGASTLSALS
GVGKGIKWLSNINMGLSFFILLFFLAFGSTFFGLQALVVGIFDYLISIPGNIFTVWVSDGVDGSEAAGLAGWQGGWTIFY
WAWWIAFAPFVGVFLARISKGRTVREYVLGAMIVPAIMCFTWFAIVGGTAIDLELNGGAGGAIQDAGQSDQLFAMLAVML
SDNLAWIMSVIVVILLLTYLVTSADSAVLIINTINAAGDEGPKARPHIIFWGAALALVVGGLIIAGGLGAIQAAMVIGAL
PFSLVMVLMGLALIKAIINDSRREKQGVATTHDEIDTVPAE
>Mature_601_residues
MRHAGLWLRIRNTGDITMAIEPPITDLDIPTADSGFYKGFTKIVALTGKFLVAVLIIWALLPAASLTFGPAAEGSTSLFI
DADGNVSAAAGVVLGGINSLILATFNYWYVYVMAFFVILCIILALWPASGRLKMGLDDDKPEFTNFSWFSMMFGAGIGIG
MLTFATAEPMYHWGSNPSTIQGITEGSTAGNVRDAYIWSFTHWGLAAWASYAIVGLALGYFAYRRSLPLTIRSALVPIFG
KSMEGGLGHAVDIVAVVATVLGVSQTLGFGVEQFISGLTRIGVGDWLQQTAEDGSVSASTAGIIVALMVIMGASTLSALS
GVGKGIKWLSNINMGLSFFILLFFLAFGSTFFGLQALVVGIFDYLISIPGNIFTVWVSDGVDGSEAAGLAGWQGGWTIFY
WAWWIAFAPFVGVFLARISKGRTVREYVLGAMIVPAIMCFTWFAIVGGTAIDLELNGGAGGAIQDAGQSDQLFAMLAVML
SDNLAWIMSVIVVILLLTYLVTSADSAVLIINTINAAGDEGPKARPHIIFWGAALALVVGGLIIAGGLGAIQAAMVIGAL
PFSLVMVLMGLALIKAIINDSRREKQGVATTHDEIDTVPAE

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=492, Percent_Identity=36.5853658536585, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1786224, Length=501, Percent_Identity=26.9461077844311, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788102, Length=470, Percent_Identity=24.0425531914894, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 63558; Mature: 63558

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHAGLWLRIRNTGDITMAIEPPITDLDIPTADSGFYKGFTKIVALTGKFLVAVLIIWAL
CCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPAASLTFGPAAEGSTSLFIDADGNVSAAAGVVLGGINSLILATFNYWYVYVMAFFVILC
HHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILALWPASGRLKMGLDDDKPEFTNFSWFSMMFGAGIGIGMLTFATAEPMYHWGSNPSTI
HHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCE
QGITEGSTAGNVRDAYIWSFTHWGLAAWASYAIVGLALGYFAYRRSLPLTIRSALVPIFG
ECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
KSMEGGLGHAVDIVAVVATVLGVSQTLGFGVEQFISGLTRIGVGDWLQQTAEDGSVSAST
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
AGIIVALMVIMGASTLSALSGVGKGIKWLSNINMGLSFFILLFFLAFGSTFFGLQALVVG
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
IFDYLISIPGNIFTVWVSDGVDGSEAAGLAGWQGGWTIFYWAWWIAFAPFVGVFLARISK
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GRTVREYVLGAMIVPAIMCFTWFAIVGGTAIDLELNGGAGGAIQDAGQSDQLFAMLAVML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SDNLAWIMSVIVVILLLTYLVTSADSAVLIINTINAAGDEGPKARPHIIFWGAALALVVG
HCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHH
GLIIAGGLGAIQAAMVIGALPFSLVMVLMGLALIKAIINDSRREKQGVATTHDEIDTVPA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHCCCCCC
E
C
>Mature Secondary Structure
MRHAGLWLRIRNTGDITMAIEPPITDLDIPTADSGFYKGFTKIVALTGKFLVAVLIIWAL
CCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPAASLTFGPAAEGSTSLFIDADGNVSAAAGVVLGGINSLILATFNYWYVYVMAFFVILC
HHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILALWPASGRLKMGLDDDKPEFTNFSWFSMMFGAGIGIGMLTFATAEPMYHWGSNPSTI
HHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCCCE
QGITEGSTAGNVRDAYIWSFTHWGLAAWASYAIVGLALGYFAYRRSLPLTIRSALVPIFG
ECCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
KSMEGGLGHAVDIVAVVATVLGVSQTLGFGVEQFISGLTRIGVGDWLQQTAEDGSVSAST
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCHH
AGIIVALMVIMGASTLSALSGVGKGIKWLSNINMGLSFFILLFFLAFGSTFFGLQALVVG
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
IFDYLISIPGNIFTVWVSDGVDGSEAAGLAGWQGGWTIFYWAWWIAFAPFVGVFLARISK
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GRTVREYVLGAMIVPAIMCFTWFAIVGGTAIDLELNGGAGGAIQDAGQSDQLFAMLAVML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SDNLAWIMSVIVVILLLTYLVTSADSAVLIINTINAAGDEGPKARPHIIFWGAALALVVG
HCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHH
GLIIAGGLGAIQAAMVIGALPFSLVMVLMGLALIKAIINDSRREKQGVATTHDEIDTVPA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]