| Definition | Jannaschia sp. CCS1 chromosome, complete genome. |
|---|---|
| Accession | NC_007802 |
| Length | 4,317,977 |
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The map label for this gene is lcfB [H]
Identifier: 89054058
GI number: 89054058
Start: 1543349
End: 1544833
Strand: Direct
Name: lcfB [H]
Synonym: Jann_1567
Alternate gene names: 89054058
Gene position: 1543349-1544833 (Clockwise)
Preceding gene: 89054057
Following gene: 89054060
Centisome position: 35.74
GC content: 65.19
Gene sequence:
>1485_bases GTGATCTTCGATCCGGCCGCGCCACCGGAAGGCACCATACGCGACTGGATCGACGCGCGGGCGGAGGCCGGGGGGACGGC GTTTGTCTTCCCCGACAGCGACCCACTCAGCTGGGACGCCTTGCGCGTACAGGTTCGCGATATGGCCGAGGGCCTGATCG GGCACGGCGTGCGGAAGGGCGAAAGCCTCGCCATCATTCATCCCAATGGTCGCGACGGAATACTGGCGCTGTTCGCCGCG CTTTATGCCGGGTGTCGGGCCACGATGATTAACCTTGCCGCAGGCCCCGACGCCATCGCCTATGCGCTGGAGCATTCCGG TGCGCGGTTCGCTTTCGTGCACGCGGATCAAATGGAGACCCTTGCCCGGATAGCCCCCGAGGGCCTCACCGCCCTGACGT CCAAGCACTTGATCCAAAAGGCCGATCTGCCGGATCTGACGCCCGATGACCATGCACTGCTGATGTATACCTCGGGGACC ACCGGCAAGCCCAAGGGTGTCGTCCACAGCCAGTCCAGCCTTCTGGCGGGGGGCTGGACCACTGCCGTCGCCCACGCCCT GACCGCGCAGGATCGTGCCTGCTGCGTCCTGCCGATTTATCACATCAACGGCCTCTGCGTCAGCCTCATGGGCACGCTGG TCTCGGGCGGCTCCGCGCTGATCTTGCCCAAATTCTCGGCCAGCCGCTTCTGGGATCAGGCCGACGCGGCGCAGATCACC TGGTTCTCGGTCGTGCCGACAATCATCAGCCATTTGCTCCACGGCGAGGCTGACCCAAAGCCCATCACCCGGGCGCGTCT GCGCTTTGGACGTTCGGCCTCCTCGGCGCTGGCCGTTGAGACGCAGGCAGCCTTCGAGAGCCGCTTTGGCGTGCCAATCA TTGAGACGATGGGCCTGACGGAAACGGCCGCGCAGATCCTGTCCAACCCGCTGCCGCCGGGCGTGCGTAAGATCGGATCG CCCGGCGTGGGCTTCGGTTGTGAGGTCCGCATCCTGGCCCCCGACATTTCCGAGGCCCCATATGGCATAGAAGGGGAGAT TGCGGTGCGCGGTCCCAACGTGATGCGCGAATACCTGCACAATCCGGACGCTACCGCCGCCACGTTCGCGGGCGATTGGC TGCGCACCGGCGATCTGGGGCGGATGGATGCGGACGGATATGTCTTCGTCACCGGTCGCCTGAAAGAGTTGATCATCAAG GGCGGAGAAAACATCGCGCCCCGTGAGATTGACGAGGTGCTCTACAGCCATGCCGATGTGATCGAGGCGGCAGCCTTCGC GCGCGCCTGCCCGCAATATGGGGAACGGGTGGAGGTGGCGCTGGCTTTGCGGGACGGCTCGGCGCTGTCGGCAGATGACG TCATCGCGCTGTGCCACGCGCGCCTGGGACCGTTCAAATCGCCCGACCGCGTCCATTTTATGGCGGAACTGCCCAAAGGC CCGTCCGGCAAGATCCAGCGGCTCAAACTGGCGGAACTGGTCTAG
Upstream 100 bases:
>100_bases GGAAGCACTTCCTGCAATCCACCAAGATCGTGCGGGAAATCCCGGCGCGTGAACCCAGCCTTGAAGACATCTTTGGCGCA TATTGGGCGGAGGCGGGCAA
Downstream 100 bases:
>100_bases GCGCGGCTATCCTGACTATCCCGGCTATTTTGGCGGCCCCTGCGGTGTCAGGTCGGTAAACGGAAAGCCGGTGGCGGCTT CAAACTCCGCCTCATCCCAG
Product: AMP-dependent synthetase and ligase
Products: NA
Alternate protein names: Long-chain acyl-CoA synthetase [H]
Number of amino acids: Translated: 494; Mature: 494
Protein sequence:
>494_residues MIFDPAAPPEGTIRDWIDARAEAGGTAFVFPDSDPLSWDALRVQVRDMAEGLIGHGVRKGESLAIIHPNGRDGILALFAA LYAGCRATMINLAAGPDAIAYALEHSGARFAFVHADQMETLARIAPEGLTALTSKHLIQKADLPDLTPDDHALLMYTSGT TGKPKGVVHSQSSLLAGGWTTAVAHALTAQDRACCVLPIYHINGLCVSLMGTLVSGGSALILPKFSASRFWDQADAAQIT WFSVVPTIISHLLHGEADPKPITRARLRFGRSASSALAVETQAAFESRFGVPIIETMGLTETAAQILSNPLPPGVRKIGS PGVGFGCEVRILAPDISEAPYGIEGEIAVRGPNVMREYLHNPDATAATFAGDWLRTGDLGRMDADGYVFVTGRLKELIIK GGENIAPREIDEVLYSHADVIEAAAFARACPQYGERVEVALALRDGSALSADDVIALCHARLGPFKSPDRVHFMAELPKG PSGKIQRLKLAELV
Sequences:
>Translated_494_residues MIFDPAAPPEGTIRDWIDARAEAGGTAFVFPDSDPLSWDALRVQVRDMAEGLIGHGVRKGESLAIIHPNGRDGILALFAA LYAGCRATMINLAAGPDAIAYALEHSGARFAFVHADQMETLARIAPEGLTALTSKHLIQKADLPDLTPDDHALLMYTSGT TGKPKGVVHSQSSLLAGGWTTAVAHALTAQDRACCVLPIYHINGLCVSLMGTLVSGGSALILPKFSASRFWDQADAAQIT WFSVVPTIISHLLHGEADPKPITRARLRFGRSASSALAVETQAAFESRFGVPIIETMGLTETAAQILSNPLPPGVRKIGS PGVGFGCEVRILAPDISEAPYGIEGEIAVRGPNVMREYLHNPDATAATFAGDWLRTGDLGRMDADGYVFVTGRLKELIIK GGENIAPREIDEVLYSHADVIEAAAFARACPQYGERVEVALALRDGSALSADDVIALCHARLGPFKSPDRVHFMAELPKG PSGKIQRLKLAELV >Mature_494_residues MIFDPAAPPEGTIRDWIDARAEAGGTAFVFPDSDPLSWDALRVQVRDMAEGLIGHGVRKGESLAIIHPNGRDGILALFAA LYAGCRATMINLAAGPDAIAYALEHSGARFAFVHADQMETLARIAPEGLTALTSKHLIQKADLPDLTPDDHALLMYTSGT TGKPKGVVHSQSSLLAGGWTTAVAHALTAQDRACCVLPIYHINGLCVSLMGTLVSGGSALILPKFSASRFWDQADAAQIT WFSVVPTIISHLLHGEADPKPITRARLRFGRSASSALAVETQAAFESRFGVPIIETMGLTETAAQILSNPLPPGVRKIGS PGVGFGCEVRILAPDISEAPYGIEGEIAVRGPNVMREYLHNPDATAATFAGDWLRTGDLGRMDADGYVFVTGRLKELIIK GGENIAPREIDEVLYSHADVIEAAAFARACPQYGERVEVALALRDGSALSADDVIALCHARLGPFKSPDRVHFMAELPKG PSGKIQRLKLAELV
Specific function: Involved in the degradation of long-chain fatty acids [H]
COG id: COG0318
COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]
Homologues:
Organism=Homo sapiens, GI187761345, Length=465, Percent_Identity=27.5268817204301, Blast_Score=159, Evalue=7e-39, Organism=Homo sapiens, GI187761343, Length=465, Percent_Identity=27.5268817204301, Blast_Score=159, Evalue=7e-39, Organism=Homo sapiens, GI156151445, Length=511, Percent_Identity=25.440313111546, Blast_Score=134, Evalue=2e-31, Organism=Homo sapiens, GI38505220, Length=376, Percent_Identity=32.9787234042553, Blast_Score=122, Evalue=6e-28, Organism=Homo sapiens, GI42544132, Length=438, Percent_Identity=26.027397260274, Blast_Score=119, Evalue=6e-27, Organism=Homo sapiens, GI58082049, Length=475, Percent_Identity=26.7368421052632, Blast_Score=119, Evalue=7e-27, Organism=Homo sapiens, GI8923896, Length=555, Percent_Identity=24.5045045045045, Blast_Score=117, Evalue=2e-26, Organism=Homo sapiens, GI157311624, Length=475, Percent_Identity=26.3157894736842, Blast_Score=116, Evalue=4e-26, Organism=Homo sapiens, GI157311622, Length=475, Percent_Identity=26.3157894736842, Blast_Score=116, Evalue=4e-26, Organism=Homo sapiens, GI253970489, Length=369, Percent_Identity=28.7262872628726, Blast_Score=113, Evalue=4e-25, Organism=Homo sapiens, GI122937307, Length=468, Percent_Identity=27.5641025641026, Blast_Score=110, Evalue=4e-24, Organism=Homo sapiens, GI115511026, Length=470, Percent_Identity=24.8936170212766, Blast_Score=103, Evalue=4e-22, Organism=Homo sapiens, GI27477105, Length=517, Percent_Identity=25.9187620889749, Blast_Score=103, Evalue=5e-22, Organism=Homo sapiens, GI13325057, Length=469, Percent_Identity=25.7995735607676, Blast_Score=102, Evalue=1e-21, Organism=Homo sapiens, GI62865631, Length=522, Percent_Identity=22.9885057471264, Blast_Score=96, Evalue=9e-20, Organism=Homo sapiens, GI13325055, Length=522, Percent_Identity=22.9885057471264, Blast_Score=96, Evalue=9e-20, Organism=Homo sapiens, GI28416953, Length=533, Percent_Identity=23.2645403377111, Blast_Score=93, Evalue=5e-19, Organism=Homo sapiens, GI40807357, Length=529, Percent_Identity=23.6294896030246, Blast_Score=90, Evalue=5e-18, Organism=Homo sapiens, GI38524616, Length=483, Percent_Identity=25.2587991718427, Blast_Score=89, Evalue=7e-18, Organism=Homo sapiens, GI227499619, Length=486, Percent_Identity=21.6049382716049, Blast_Score=87, Evalue=4e-17, Organism=Homo sapiens, GI13236579, Length=502, Percent_Identity=21.7131474103586, Blast_Score=82, Evalue=1e-15, Organism=Homo sapiens, GI13375727, Length=519, Percent_Identity=24.4701348747592, Blast_Score=80, Evalue=5e-15, Organism=Escherichia coli, GI221142682, Length=483, Percent_Identity=28.1573498964803, Blast_Score=172, Evalue=3e-44, Organism=Escherichia coli, GI1788107, Length=490, Percent_Identity=27.5510204081633, Blast_Score=158, Evalue=6e-40, Organism=Escherichia coli, GI145693145, Length=346, Percent_Identity=28.9017341040462, Blast_Score=145, Evalue=6e-36, Organism=Escherichia coli, GI1789201, Length=391, Percent_Identity=27.1099744245524, Blast_Score=111, Evalue=8e-26, Organism=Escherichia coli, GI1790505, Length=515, Percent_Identity=23.495145631068, Blast_Score=105, Evalue=7e-24, Organism=Escherichia coli, GI1786810, Length=356, Percent_Identity=25.8426966292135, Blast_Score=97, Evalue=2e-21, Organism=Escherichia coli, GI1788595, Length=485, Percent_Identity=25.5670103092783, Blast_Score=97, Evalue=3e-21, Organism=Escherichia coli, GI1786529, Length=394, Percent_Identity=25.6345177664975, Blast_Score=89, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17558820, Length=341, Percent_Identity=34.6041055718475, Blast_Score=171, Evalue=8e-43, Organism=Caenorhabditis elegans, GI32563687, Length=346, Percent_Identity=31.5028901734104, Blast_Score=145, Evalue=6e-35, Organism=Caenorhabditis elegans, GI17557194, Length=538, Percent_Identity=27.1375464684015, Blast_Score=145, Evalue=7e-35, Organism=Caenorhabditis elegans, GI71994694, Length=528, Percent_Identity=23.8636363636364, Blast_Score=137, Evalue=9e-33, Organism=Caenorhabditis elegans, GI71994703, Length=528, Percent_Identity=23.8636363636364, Blast_Score=137, Evalue=1e-32, Organism=Caenorhabditis elegans, GI71994690, Length=528, Percent_Identity=23.8636363636364, Blast_Score=137, Evalue=1e-32, Organism=Caenorhabditis elegans, GI17559526, Length=358, Percent_Identity=29.3296089385475, Blast_Score=132, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17538037, Length=524, Percent_Identity=25.5725190839695, Blast_Score=128, Evalue=8e-30, Organism=Caenorhabditis elegans, GI17560140, Length=518, Percent_Identity=25.6756756756757, Blast_Score=122, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17560308, Length=519, Percent_Identity=23.121387283237, Blast_Score=118, Evalue=7e-27, Organism=Caenorhabditis elegans, GI17531443, Length=522, Percent_Identity=24.904214559387, Blast_Score=108, Evalue=8e-24, Organism=Caenorhabditis elegans, GI71985884, Length=349, Percent_Identity=28.3667621776504, Blast_Score=101, Evalue=8e-22, Organism=Caenorhabditis elegans, GI71996755, Length=509, Percent_Identity=24.1650294695481, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI71983001, Length=572, Percent_Identity=22.3776223776224, Blast_Score=88, Evalue=8e-18, Organism=Caenorhabditis elegans, GI71982997, Length=572, Percent_Identity=22.3776223776224, Blast_Score=88, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17541856, Length=324, Percent_Identity=24.3827160493827, Blast_Score=77, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6319699, Length=345, Percent_Identity=38.8405797101449, Blast_Score=247, Evalue=3e-66, Organism=Saccharomyces cerevisiae, GI6319264, Length=540, Percent_Identity=25.7407407407407, Blast_Score=113, Evalue=6e-26, Organism=Saccharomyces cerevisiae, GI6323182, Length=530, Percent_Identity=24.5283018867925, Blast_Score=107, Evalue=3e-24, Organism=Saccharomyces cerevisiae, GI6324893, Length=331, Percent_Identity=27.7945619335347, Blast_Score=95, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6320852, Length=156, Percent_Identity=30.1282051282051, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI18859661, Length=536, Percent_Identity=30.0373134328358, Blast_Score=178, Evalue=8e-45, Organism=Drosophila melanogaster, GI24581924, Length=510, Percent_Identity=27.4509803921569, Blast_Score=149, Evalue=5e-36, Organism=Drosophila melanogaster, GI21355181, Length=471, Percent_Identity=26.963906581741, Blast_Score=144, Evalue=2e-34, Organism=Drosophila melanogaster, GI24667955, Length=530, Percent_Identity=25.0943396226415, Blast_Score=124, Evalue=2e-28, Organism=Drosophila melanogaster, GI62472339, Length=530, Percent_Identity=25.0943396226415, Blast_Score=123, Evalue=3e-28, Organism=Drosophila melanogaster, GI24667959, Length=369, Percent_Identity=28.7262872628726, Blast_Score=119, Evalue=6e-27, Organism=Drosophila melanogaster, GI24656500, Length=504, Percent_Identity=25, Blast_Score=94, Evalue=2e-19, Organism=Drosophila melanogaster, GI17933690, Length=477, Percent_Identity=23.8993710691824, Blast_Score=91, Evalue=2e-18, Organism=Drosophila melanogaster, GI19922652, Length=372, Percent_Identity=26.3440860215054, Blast_Score=90, Evalue=4e-18, Organism=Drosophila melanogaster, GI21356441, Length=353, Percent_Identity=25.4957507082153, Blast_Score=87, Evalue=3e-17, Organism=Drosophila melanogaster, GI24648260, Length=353, Percent_Identity=27.1954674220963, Blast_Score=82, Evalue=1e-15, Organism=Drosophila melanogaster, GI21355225, Length=537, Percent_Identity=24.0223463687151, Blast_Score=81, Evalue=2e-15, Organism=Drosophila melanogaster, GI21356947, Length=362, Percent_Identity=26.2430939226519, Blast_Score=80, Evalue=3e-15, Organism=Drosophila melanogaster, GI21358303, Length=461, Percent_Identity=21.2581344902386, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI161076582, Length=381, Percent_Identity=24.9343832020997, Blast_Score=75, Evalue=1e-13, Organism=Drosophila melanogaster, GI281365686, Length=138, Percent_Identity=29.7101449275362, Blast_Score=73, Evalue=6e-13, Organism=Drosophila melanogaster, GI24653035, Length=374, Percent_Identity=24.5989304812834, Blast_Score=72, Evalue=9e-13, Organism=Drosophila melanogaster, GI19921316, Length=123, Percent_Identity=39.8373983739837, Blast_Score=71, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648253, Length=458, Percent_Identity=22.4890829694323, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648257, Length=347, Percent_Identity=25.0720461095101, Blast_Score=70, Evalue=4e-12, Organism=Drosophila melanogaster, GI24648255, Length=458, Percent_Identity=22.2707423580786, Blast_Score=67, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020459 - InterPro: IPR020845 - InterPro: IPR000873 [H]
Pfam domain/function: PF00501 AMP-binding [H]
EC number: =6.2.1.3 [H]
Molecular weight: Translated: 52573; Mature: 52573
Theoretical pI: Translated: 5.99; Mature: 5.99
Prosite motif: PS00455 AMP_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIFDPAAPPEGTIRDWIDARAEAGGTAFVFPDSDPLSWDALRVQVRDMAEGLIGHGVRKG CCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC ESLAIIHPNGRDGILALFAALYAGCRATMINLAAGPDAIAYALEHSGARFAFVHADQMET CEEEEECCCCCCHHHHHHHHHHHCCHHEEEEECCCCHHHHHHHHCCCCEEEEEEHHHHHH LARIAPEGLTALTSKHLIQKADLPDLTPDDHALLMYTSGTTGKPKGVVHSQSSLLAGGWT HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEECCCCEECCCHH TAVAHALTAQDRACCVLPIYHINGLCVSLMGTLVSGGSALILPKFSASRFWDQADAAQIT HHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCEEH WFSVVPTIISHLLHGEADPKPITRARLRFGRSASSALAVETQAAFESRFGVPIIETMGLT HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCHHHHCCCH ETAAQILSNPLPPGVRKIGSPGVGFGCEVRILAPDISEAPYGIEGEIAVRGPNVMREYLH HHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHC NPDATAATFAGDWLRTGDLGRMDADGYVFVTGRLKELIIKGGENIAPREIDEVLYSHADV CCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHH IEAAAFARACPQYGERVEVALALRDGSALSADDVIALCHARLGPFKSPDRVHFMAELPKG HHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCC PSGKIQRLKLAELV CCCCHHEEEHHHCC >Mature Secondary Structure MIFDPAAPPEGTIRDWIDARAEAGGTAFVFPDSDPLSWDALRVQVRDMAEGLIGHGVRKG CCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC ESLAIIHPNGRDGILALFAALYAGCRATMINLAAGPDAIAYALEHSGARFAFVHADQMET CEEEEECCCCCCHHHHHHHHHHHCCHHEEEEECCCCHHHHHHHHCCCCEEEEEEHHHHHH LARIAPEGLTALTSKHLIQKADLPDLTPDDHALLMYTSGTTGKPKGVVHSQSSLLAGGWT HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEECCCCEECCCHH TAVAHALTAQDRACCVLPIYHINGLCVSLMGTLVSGGSALILPKFSASRFWDQADAAQIT HHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCEEH WFSVVPTIISHLLHGEADPKPITRARLRFGRSASSALAVETQAAFESRFGVPIIETMGLT HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCHHHHCCCH ETAAQILSNPLPPGVRKIGSPGVGFGCEVRILAPDISEAPYGIEGEIAVRGPNVMREYLH HHHHHHHCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHC NPDATAATFAGDWLRTGDLGRMDADGYVFVTGRLKELIIKGGENIAPREIDEVLYSHADV CCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHH IEAAAFARACPQYGERVEVALALRDGSALSADDVIALCHARLGPFKSPDRVHFMAELPKG HHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCC PSGKIQRLKLAELV CCCCHHEEEHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9579061; 9384377 [H]