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The map label for this gene is sucD [H]

Identifier: 89054057

GI number: 89054057

Start: 1541949

End: 1543352

Strand: Direct

Name: sucD [H]

Synonym: Jann_1566

Alternate gene names: 89054057

Gene position: 1541949-1543352 (Clockwise)

Preceding gene: 89054056

Following gene: 89054058

Centisome position: 35.71

GC content: 64.03

Gene sequence:

>1404_bases
GTGACCGATCTTGATCCCATTGCCGAGGTAGACGCCATCGTCGCCCGGGCCCGTGCGGCCCAGGCAGGTTATGAAGCGGG
CGGGTCACAGGCCCTTTATGATCGCGCGGCCCAAGCCGCCGCCTGGGCGATCATGGAGCCTGCGCGCAACCGGCAACTGG
CCGAACTGGCGGTGGAAACGACGGGCCTGGGCAACGTGCCCGACAAGATCACCAAGAACCACCGAAAGACGCTCGGCCTG
ATGCGCGATATCGCGGATGTGGTGACCTATGGCGTGATCCGCGATGACCCGCGCACCGGTATCACGGAAATCGCGCGGCC
CATCGGCGTGATCGGCGCGGTGGTGCCGTCGACCAACCCCGGGGCCACGCCCGCCAACAACATCATCAACGCGTTGAAAT
GCGGCAATGCCATCGTCGTGTCGCCATCGCCCAAGGGCGTGCCGACCTGTGAGGCGCTGTTGGGCTACGTGCATGCGGAA
TTCGACAAGGCCGGGATTGATCGCGATCTGGTGCTGATGATCCCGGGACGCGGATCGAAAGAGAAGACCCAGCGCCTGTT
GGAGACGTCGGATATGATCGTCGTCACGGGCAGTCAGAACAACGTGCGCCGGGCCTATACATCGGGCACGCCCGCGCTGG
CCGTGGGGGCGGGCAATGTCTGCGTCATTGTGGATGAGACGGCGGATCTGGCGGATGCGGCGAGCAAGATCGCGGCATCG
AAGTGCTTTGACAACGCGACCTCGTGTTCGTCGGAAAATGCGATTGTGGTCGTGGATGCGGTCTACGATGCCTTCGTGGC
GGAGATGGCCAAGACCGGCGGCGCGTTGATCGCCGACGAGACCCGCGTGACCGACACGCTGTGGGTCAGGGGCACACTGA
ACCCGCGCGCCATCGCGCAGGACGCGAGCGACATGATCGCGGCGTTGGGCCTGACGGGCGAGGTGCCTGATGATACGCAA
TACATCGCCGTGGAGACCAGTGGCATAGGCCCGGACCATCCGCTTTCGGGCGAAAAGCTGAGCCGTGTGCTGACGGTCTA
CCGCGCGAGTGATTTCGATGATGCCGTGGAGACGACGCTGAAGGTGCAACTGCATCAGGGCGCGGGGCATTCCGTGGGGA
TCCACACCGCTGACCCGGACCGCCCCATGGTAATGGCCCGCGCGATCCCCACCAGCCGCGTCATCGTCAACCAGGCCCAT
ACCTTCGCCACGGGCGGGTCGTTCACCAACGGAATGCCGTTTTCCCTGTCCATGGGCTGCGGGTCCTGGGGCGGCAATTC
CATCGATGAGAACCTGCATTGGAAGCACTTCCTGCAATCCACCAAGATCGTGCGGGAAATCCCGGCGCGTGAACCCAGCC
TTGAAGACATCTTTGGCGCATATTGGGCGGAGGCGGGCAAGTGA

Upstream 100 bases:

>100_bases
TCAGGAAACGCTGGAAGCGCTGCTGGCTGATCTGGACAACTGAGCCTAGGGCCGGGGCGGGCCACAGGCGCTCGCCCCCG
TTTTCCATAAGGATTTCCCC

Downstream 100 bases:

>100_bases
TCTTCGATCCGGCCGCGCCACCGGAAGGCACCATACGCGACTGGATCGACGCGCGGGCGGAGGCCGGGGGGACGGCGTTT
GTCTTCCCCGACAGCGACCC

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTDLDPIAEVDAIVARARAAQAGYEAGGSQALYDRAAQAAAWAIMEPARNRQLAELAVETTGLGNVPDKITKNHRKTLGL
MRDIADVVTYGVIRDDPRTGITEIARPIGVIGAVVPSTNPGATPANNIINALKCGNAIVVSPSPKGVPTCEALLGYVHAE
FDKAGIDRDLVLMIPGRGSKEKTQRLLETSDMIVVTGSQNNVRRAYTSGTPALAVGAGNVCVIVDETADLADAASKIAAS
KCFDNATSCSSENAIVVVDAVYDAFVAEMAKTGGALIADETRVTDTLWVRGTLNPRAIAQDASDMIAALGLTGEVPDDTQ
YIAVETSGIGPDHPLSGEKLSRVLTVYRASDFDDAVETTLKVQLHQGAGHSVGIHTADPDRPMVMARAIPTSRVIVNQAH
TFATGGSFTNGMPFSLSMGCGSWGGNSIDENLHWKHFLQSTKIVREIPAREPSLEDIFGAYWAEAGK

Sequences:

>Translated_467_residues
MTDLDPIAEVDAIVARARAAQAGYEAGGSQALYDRAAQAAAWAIMEPARNRQLAELAVETTGLGNVPDKITKNHRKTLGL
MRDIADVVTYGVIRDDPRTGITEIARPIGVIGAVVPSTNPGATPANNIINALKCGNAIVVSPSPKGVPTCEALLGYVHAE
FDKAGIDRDLVLMIPGRGSKEKTQRLLETSDMIVVTGSQNNVRRAYTSGTPALAVGAGNVCVIVDETADLADAASKIAAS
KCFDNATSCSSENAIVVVDAVYDAFVAEMAKTGGALIADETRVTDTLWVRGTLNPRAIAQDASDMIAALGLTGEVPDDTQ
YIAVETSGIGPDHPLSGEKLSRVLTVYRASDFDDAVETTLKVQLHQGAGHSVGIHTADPDRPMVMARAIPTSRVIVNQAH
TFATGGSFTNGMPFSLSMGCGSWGGNSIDENLHWKHFLQSTKIVREIPAREPSLEDIFGAYWAEAGK
>Mature_466_residues
TDLDPIAEVDAIVARARAAQAGYEAGGSQALYDRAAQAAAWAIMEPARNRQLAELAVETTGLGNVPDKITKNHRKTLGLM
RDIADVVTYGVIRDDPRTGITEIARPIGVIGAVVPSTNPGATPANNIINALKCGNAIVVSPSPKGVPTCEALLGYVHAEF
DKAGIDRDLVLMIPGRGSKEKTQRLLETSDMIVVTGSQNNVRRAYTSGTPALAVGAGNVCVIVDETADLADAASKIAASK
CFDNATSCSSENAIVVVDAVYDAFVAEMAKTGGALIADETRVTDTLWVRGTLNPRAIAQDASDMIAALGLTGEVPDDTQY
IAVETSGIGPDHPLSGEKLSRVLTVYRASDFDDAVETTLKVQLHQGAGHSVGIHTADPDRPMVMARAIPTSRVIVNQAHT
FATGGSFTNGMPFSLSMGCGSWGGNSIDENLHWKHFLQSTKIVREIPAREPSLEDIFGAYWAEAGK

Specific function: Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787493, Length=447, Percent_Identity=35.7941834451902, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1788797, Length=378, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.76 [H]

Molecular weight: Translated: 49233; Mature: 49102

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLDPIAEVDAIVARARAAQAGYEAGGSQALYDRAAQAAAWAIMEPARNRQLAELAVET
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
TGLGNVPDKITKNHRKTLGLMRDIADVVTYGVIRDDPRTGITEIARPIGVIGAVVPSTNP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCC
GATPANNIINALKCGNAIVVSPSPKGVPTCEALLGYVHAEFDKAGIDRDLVLMIPGRGSK
CCCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
EKTQRLLETSDMIVVTGSQNNVRRAYTSGTPALAVGAGNVCVIVDETADLADAASKIAAS
HHHHHHHHCCCEEEEECCCCCCEEEECCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHH
KCFDNATSCSSENAIVVVDAVYDAFVAEMAKTGGALIADETRVTDTLWVRGTLNPRAIAQ
HHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCHHHHHH
DASDMIAALGLTGEVPDDTQYIAVETSGIGPDHPLSGEKLSRVLTVYRASDFDDAVETTL
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEE
KVQLHQGAGHSVGIHTADPDRPMVMARAIPTSRVIVNQAHTFATGGSFTNGMPFSLSMGC
EEEEECCCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCEEECCCCCCCCCCEEEECCC
GSWGGNSIDENLHWKHFLQSTKIVREIPAREPSLEDIFGAYWAEAGK
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDLDPIAEVDAIVARARAAQAGYEAGGSQALYDRAAQAAAWAIMEPARNRQLAELAVET
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
TGLGNVPDKITKNHRKTLGLMRDIADVVTYGVIRDDPRTGITEIARPIGVIGAVVPSTNP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCC
GATPANNIINALKCGNAIVVSPSPKGVPTCEALLGYVHAEFDKAGIDRDLVLMIPGRGSK
CCCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
EKTQRLLETSDMIVVTGSQNNVRRAYTSGTPALAVGAGNVCVIVDETADLADAASKIAAS
HHHHHHHHCCCEEEEECCCCCCEEEECCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHH
KCFDNATSCSSENAIVVVDAVYDAFVAEMAKTGGALIADETRVTDTLWVRGTLNPRAIAQ
HHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCHHHHHH
DASDMIAALGLTGEVPDDTQYIAVETSGIGPDHPLSGEKLSRVLTVYRASDFDDAVETTL
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEE
KVQLHQGAGHSVGIHTADPDRPMVMARAIPTSRVIVNQAHTFATGGSFTNGMPFSLSMGC
EEEEECCCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCEEECCCCCCCCCCEEEECCC
GSWGGNSIDENLHWKHFLQSTKIVREIPAREPSLEDIFGAYWAEAGK
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]