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The map label for this gene is xylH [H]

Identifier: 89053917

GI number: 89053917

Start: 1395818

End: 1397038

Strand: Direct

Name: xylH [H]

Synonym: Jann_1426

Alternate gene names: 89053917

Gene position: 1395818-1397038 (Clockwise)

Preceding gene: 89053916

Following gene: 89053918

Centisome position: 32.33

GC content: 62.0

Gene sequence:

>1221_bases
ATGCGGGGCGTGATTTCGGGGCAGGCGGCGGAGACGTTGCCTGCCCTTTTTCCATCCAAAGACACGCATAAGACATGGGG
AGACGGGGATATGAGTGAGACGGAGCCAGCGGCCGCAGGGGGCCCGAATGACGAGCGCATAAAGGACCAGGGCGGCTTTC
GAAAGTGGCTGATCCGGCCCGAACTGGGCGGCATCGTCGGCGTCATCGCGGTGTTCATCTTCTTCGGCGTCCTCGCAGGC
GACAGCGGCATGTTCAACGCGCAAGGCATCATGAACTGGAGCCAGATCAGCGCACAATTCATGATCATCGCGGTCGGCGC
CTGCATGTTGATGGTGGCCGGAGAGTTTGACCTGTCCGTCGGCTCCATGATTGGGTTTGCAGGCATTTCGATTGCGATGT
TCGGCGTGGTCTGGGGCCTGCCGATGTGGGTCGCGATCCTGATCACCTTTGCCATCTGCCTCGTCATCGGGGCGATCAAC
GGCATCATCGTGGTGCGCACCGGCCTGCCGAGTTTCATCGTGACGCTGGCCTTCCTGTTCATCCTGCGCGGCTTCACGAT
TTTCGTGCCGCAAACCGTTGAAAGCCGGACGATTATTGGCGGGATCGAGGAGGCGGCGGAGGGCGACTGGCTGGCCGCGA
TCTTCAACACGGACGTCGCGGGCTGGCTGTTCGTCTGGATGGCCGACAACGGCATCATCGGCACATTCTCGCGCGGGACC
CGGGAGGGGGAGCCGTTGATCAGCGGCATTCCGATGCTGATCGTCTGGGCCTTTATCCTGGTCATCGCGGGGCACATCAT
CCTGACGCGCACCAAGTTCGGCAACTGGATCTTCGCGGCGGGCGGAGATGCGCAGGCGGCCCGCTATGTGGGCGTGCCGG
TGGACCGGGTGAAGATCACCATGTTCATGACGACGGCGTTCTGTTCAACAGTGTTCGCTTGCTGTCAGGTGTTTGAATTT
GGGTCCGCCGCCGCAGACCGGGGCATCCTGAAGGAGTTTGAGGCGATCATCGCGGTGGTCATCGGAGGGGCGCTTTTGAC
CGGGGGATACGGCTCGGTCATGGGGGCGGCGCTGGGGGCGCTGATCTTCGGCGTCGTGCAGCAGGGGCTGTTCTTCGCGG
ATGTGGAATCGAGCCTGTTCCGGGTGTTTCTCGGCATCATCCTTCTCTTCGCGGTGGTGCTGAACACCTATATTCGCCGC
ATCATCACGGGGGAGCGTTGA

Upstream 100 bases:

>100_bases
CTCCGGCCCCGGTTTCATCACCGCTGACGGTCTGGAGCTGGTGGAAGCGCTGGCGGGCGAATACCGCTAACGCGCCGGTT
GAGGCTTTGATCTGCCCCGG

Downstream 100 bases:

>100_bases
TATGACGAACGCATCCAATATGTCGCCGTCCGGCAGCGGGCCGATCGTCCAAATGGTCGATATCAAGAAACATTTCGGTC
CGGTGATCGCGCTCAACGGC

Product: inner-membrane translocator

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRGVISGQAAETLPALFPSKDTHKTWGDGDMSETEPAAAGGPNDERIKDQGGFRKWLIRPELGGIVGVIAVFIFFGVLAG
DSGMFNAQGIMNWSQISAQFMIIAVGACMLMVAGEFDLSVGSMIGFAGISIAMFGVVWGLPMWVAILITFAICLVIGAIN
GIIVVRTGLPSFIVTLAFLFILRGFTIFVPQTVESRTIIGGIEEAAEGDWLAAIFNTDVAGWLFVWMADNGIIGTFSRGT
REGEPLISGIPMLIVWAFILVIAGHIILTRTKFGNWIFAAGGDAQAARYVGVPVDRVKITMFMTTAFCSTVFACCQVFEF
GSAAADRGILKEFEAIIAVVIGGALLTGGYGSVMGAALGALIFGVVQQGLFFADVESSLFRVFLGIILLFAVVLNTYIRR
IITGER

Sequences:

>Translated_406_residues
MRGVISGQAAETLPALFPSKDTHKTWGDGDMSETEPAAAGGPNDERIKDQGGFRKWLIRPELGGIVGVIAVFIFFGVLAG
DSGMFNAQGIMNWSQISAQFMIIAVGACMLMVAGEFDLSVGSMIGFAGISIAMFGVVWGLPMWVAILITFAICLVIGAIN
GIIVVRTGLPSFIVTLAFLFILRGFTIFVPQTVESRTIIGGIEEAAEGDWLAAIFNTDVAGWLFVWMADNGIIGTFSRGT
REGEPLISGIPMLIVWAFILVIAGHIILTRTKFGNWIFAAGGDAQAARYVGVPVDRVKITMFMTTAFCSTVFACCQVFEF
GSAAADRGILKEFEAIIAVVIGGALLTGGYGSVMGAALGALIFGVVQQGLFFADVESSLFRVFLGIILLFAVVLNTYIRR
IITGER
>Mature_406_residues
MRGVISGQAAETLPALFPSKDTHKTWGDGDMSETEPAAAGGPNDERIKDQGGFRKWLIRPELGGIVGVIAVFIFFGVLAG
DSGMFNAQGIMNWSQISAQFMIIAVGACMLMVAGEFDLSVGSMIGFAGISIAMFGVVWGLPMWVAILITFAICLVIGAIN
GIIVVRTGLPSFIVTLAFLFILRGFTIFVPQTVESRTIIGGIEEAAEGDWLAAIFNTDVAGWLFVWMADNGIIGTFSRGT
REGEPLISGIPMLIVWAFILVIAGHIILTRTKFGNWIFAAGGDAQAARYVGVPVDRVKITMFMTTAFCSTVFACCQVFEF
GSAAADRGILKEFEAIIAVVIGGALLTGGYGSVMGAALGALIFGVVQQGLFFADVESSLFRVFLGIILLFAVVLNTYIRR
IITGER

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=360, Percent_Identity=30.2777777777778, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790191, Length=345, Percent_Identity=26.9565217391304, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788896, Length=340, Percent_Identity=27.6470588235294, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082395, Length=295, Percent_Identity=29.8305084745763, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693152, Length=301, Percent_Identity=26.9102990033223, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787794, Length=297, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790524, Length=312, Percent_Identity=24.6794871794872, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 43276; Mature: 43276

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGVISGQAAETLPALFPSKDTHKTWGDGDMSETEPAAAGGPNDERIKDQGGFRKWLIRP
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEECC
ELGGIVGVIAVFIFFGVLAGDSGMFNAQGIMNWSQISAQFMIIAVGACMLMVAGEFDLSV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GSMIGFAGISIAMFGVVWGLPMWVAILITFAICLVIGAINGIIVVRTGLPSFIVTLAFLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
ILRGFTIFVPQTVESRTIIGGIEEAAEGDWLAAIFNTDVAGWLFVWMADNGIIGTFSRGT
HHCCCEEEECCCCCCCHHHCCHHHHCCCCEEEEECCCCCCCEEEEEEECCCEEEECCCCC
REGEPLISGIPMLIVWAFILVIAGHIILTRTKFGNWIFAAGGDAQAARYVGVPVDRVKIT
CCCCHHHCCCHHHHHHHHHHHHHCHHHEEEEECCCEEEEECCCCCCCEEECCCHHHHEEH
MFMTTAFCSTVFACCQVFEFGSAAADRGILKEFEAIIAVVIGGALLTGGYGSVMGAALGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LIFGVVQQGLFFADVESSLFRVFLGIILLFAVVLNTYIRRIITGER
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRGVISGQAAETLPALFPSKDTHKTWGDGDMSETEPAAAGGPNDERIKDQGGFRKWLIRP
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEECC
ELGGIVGVIAVFIFFGVLAGDSGMFNAQGIMNWSQISAQFMIIAVGACMLMVAGEFDLSV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GSMIGFAGISIAMFGVVWGLPMWVAILITFAICLVIGAINGIIVVRTGLPSFIVTLAFLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
ILRGFTIFVPQTVESRTIIGGIEEAAEGDWLAAIFNTDVAGWLFVWMADNGIIGTFSRGT
HHCCCEEEECCCCCCCHHHCCHHHHCCCCEEEEECCCCCCCEEEEEEECCCEEEECCCCC
REGEPLISGIPMLIVWAFILVIAGHIILTRTKFGNWIFAAGGDAQAARYVGVPVDRVKIT
CCCCHHHCCCHHHHHHHHHHHHHCHHHEEEEECCCEEEEECCCCCCCEEECCCHHHHEEH
MFMTTAFCSTVFACCQVFEFGSAAADRGILKEFEAIIAVVIGGALLTGGYGSVMGAALGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LIFGVVQQGLFFADVESSLFRVFLGIILLFAVVLNTYIRRIITGER
HHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]