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The map label for this gene is dgdA [H]

Identifier: 89053868

GI number: 89053868

Start: 1345777

End: 1347066

Strand: Reverse

Name: dgdA [H]

Synonym: Jann_1377

Alternate gene names: 89053868

Gene position: 1347066-1345777 (Counterclockwise)

Preceding gene: 89053869

Following gene: 89053867

Centisome position: 31.2

GC content: 59.38

Gene sequence:

>1290_bases
ATGGCACGCACGCAGCAACAACTTTTGTCGGATCGCGCTCGGCTTCTTGGGCCAAACGTTTCGACTTTCTATAATGACCC
TGTGCATATCGTGAAGGGCGATGGCGTTTGGCTTTGGGAAGCGGAGGGGCGCAAGTATCTGGATTGTTACAACAATGTCC
CGCATGTGGGCCATTGCAATCCGCGCGTGGTTGACGCGATCTGCCAGCAGGCCAGTACGCTCAATACCCACACACGATAC
CTCCACGACGGCATTCTAGACTATGTTGAGGCGTTGACGGCAACCATGGCCCCATCCCTGAACACCGCGATCCTGACCTG
CACCGGGTCCGAGGCCAACGACATCGCGCTGCGCACGGCAGAGGCTGTGACCGGCAAACGCGGGATCATCGCAACGGACG
CCACATATCATGGCAATACAGCGCTCGTGAGCCAGTTGAGCCGCTCCAACGTGCCGGCGGTGGGCTTTGGTCTTGGCCAA
TATGTCCGCTTTGTCGACGCCCCCGACAGCTACCGCACGCCGGACCATGATGGTCAGATCTTTGCCGCCAGCGTGGCCCA
TCAAATCGCCGCGTGGGAAGAGGATGGTACGGGTTTTGCCGCTCTCATCATATGCCCCTACATGCTGAACGAAGGCTTCC
CCGATCACCCCGATGGATGGCTGAAACCCACGGCTGACGTGGTGCGCAAAGCGGGTGGGTTGCTGATCTGCGATGAGGTG
CAATCTGGCTTTGGCCGCACGGGCACGCATATGTGGGCCCATGAGAAGATGGGCGTCGTGCCGGATATCATGACGCTCGG
TAAGCCGATGGCCAACGGTCACCCTGTGGGTGGCGTGGTGGCCAACAGCGACCTGATTGCCACGTTCCGAGAGGGGTATC
GGTATTTCAACACCTTTGGCGGAAATCCCGTATCCTGCGCGGCGGCGATGGCGGTGCTGGAGGAGTTACAAGAGGCCGAC
TTGATCGCCAATGCCAAATGTGTCGGCGATCACGCGCGCCGAAGGTTGCTGACGTTGAGAGAAAAACACGACGTGATCGG
CGACGTGCGCGGCTCGGGCCTGATCTTCGGGGCTGAACTGGTGCTGGACCGGACCAGCAAAGCCCCTGCGAGCGGTTACA
CCGACCAGATCATCAACGAGATGCGGCACCGCGGGATCCTGCATTCCAAACTAGGCCGTCACAAGAACACCCTGAAGATC
CGACCGCCAATGCCATTTTCTGTGGAACATGTGGATCTGCTGCTGGATACACTGGATGAGGTGTTGAGCCACGTTCCGCT
GTCCCCATGA

Upstream 100 bases:

>100_bases
GACAAAGCCGCCGCTTGCAACGCGATCAGCACCCTAGTTTCTGCTATGCACGGCGCAACTGTCACGCTATTAGTTAACAT
AGCAATTAAATGGGCGCCCT

Downstream 100 bases:

>100_bases
GCCGGGATGTGGACGACGCGCTTGCCGTTTGGGATCTGACGGGCGCCGCCTATCGGCTTGTGGCCGCGCGGGAAAACGCC
GTCTACGAGGTTACGAACGG

Product: aminotransferase

Products: NA

Alternate protein names: DGD [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MARTQQQLLSDRARLLGPNVSTFYNDPVHIVKGDGVWLWEAEGRKYLDCYNNVPHVGHCNPRVVDAICQQASTLNTHTRY
LHDGILDYVEALTATMAPSLNTAILTCTGSEANDIALRTAEAVTGKRGIIATDATYHGNTALVSQLSRSNVPAVGFGLGQ
YVRFVDAPDSYRTPDHDGQIFAASVAHQIAAWEEDGTGFAALIICPYMLNEGFPDHPDGWLKPTADVVRKAGGLLICDEV
QSGFGRTGTHMWAHEKMGVVPDIMTLGKPMANGHPVGGVVANSDLIATFREGYRYFNTFGGNPVSCAAAMAVLEELQEAD
LIANAKCVGDHARRRLLTLREKHDVIGDVRGSGLIFGAELVLDRTSKAPASGYTDQIINEMRHRGILHSKLGRHKNTLKI
RPPMPFSVEHVDLLLDTLDEVLSHVPLSP

Sequences:

>Translated_429_residues
MARTQQQLLSDRARLLGPNVSTFYNDPVHIVKGDGVWLWEAEGRKYLDCYNNVPHVGHCNPRVVDAICQQASTLNTHTRY
LHDGILDYVEALTATMAPSLNTAILTCTGSEANDIALRTAEAVTGKRGIIATDATYHGNTALVSQLSRSNVPAVGFGLGQ
YVRFVDAPDSYRTPDHDGQIFAASVAHQIAAWEEDGTGFAALIICPYMLNEGFPDHPDGWLKPTADVVRKAGGLLICDEV
QSGFGRTGTHMWAHEKMGVVPDIMTLGKPMANGHPVGGVVANSDLIATFREGYRYFNTFGGNPVSCAAAMAVLEELQEAD
LIANAKCVGDHARRRLLTLREKHDVIGDVRGSGLIFGAELVLDRTSKAPASGYTDQIINEMRHRGILHSKLGRHKNTLKI
RPPMPFSVEHVDLLLDTLDEVLSHVPLSP
>Mature_428_residues
ARTQQQLLSDRARLLGPNVSTFYNDPVHIVKGDGVWLWEAEGRKYLDCYNNVPHVGHCNPRVVDAICQQASTLNTHTRYL
HDGILDYVEALTATMAPSLNTAILTCTGSEANDIALRTAEAVTGKRGIIATDATYHGNTALVSQLSRSNVPAVGFGLGQY
VRFVDAPDSYRTPDHDGQIFAASVAHQIAAWEEDGTGFAALIICPYMLNEGFPDHPDGWLKPTADVVRKAGGLLICDEVQ
SGFGRTGTHMWAHEKMGVVPDIMTLGKPMANGHPVGGVVANSDLIATFREGYRYFNTFGGNPVSCAAAMAVLEELQEADL
IANAKCVGDHARRRLLTLREKHDVIGDVRGSGLIFGAELVLDRTSKAPASGYTDQIINEMRHRGILHSKLGRHKNTLKIR
PPMPFSVEHVDLLLDTLDEVLSHVPLSP

Specific function: The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=429, Percent_Identity=39.3939393939394, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI226442705, Length=429, Percent_Identity=38.2284382284382, Blast_Score=299, Evalue=3e-81,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=37.2685185185185, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI226442709, Length=376, Percent_Identity=39.8936170212766, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI13994255, Length=444, Percent_Identity=30.1801801801802, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=29.4871794871795, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI188536080, Length=437, Percent_Identity=24.2562929061785, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI38679950, Length=437, Percent_Identity=24.2562929061785, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI38679946, Length=437, Percent_Identity=24.2562929061785, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI284507298, Length=206, Percent_Identity=31.5533980582524, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1789016, Length=429, Percent_Identity=29.3706293706294, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI145693181, Length=401, Percent_Identity=28.927680798005, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1788044, Length=408, Percent_Identity=28.6764705882353, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789759, Length=340, Percent_Identity=27.3529411764706, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=28.1481481481481, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786349, Length=309, Percent_Identity=29.126213592233, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786991, Length=372, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992977, Length=441, Percent_Identity=34.0136054421769, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=32.9493087557604, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI25144271, Length=428, Percent_Identity=28.0373831775701, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=220, Percent_Identity=31.8181818181818, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71992985, Length=136, Percent_Identity=34.5588235294118, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=440, Percent_Identity=24.5454545454545, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=411, Percent_Identity=28.7104622871046, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=425, Percent_Identity=25.4117647058824, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=247, Percent_Identity=26.7206477732794, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356575, Length=436, Percent_Identity=38.9908256880734, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI161085790, Length=457, Percent_Identity=34.1356673960613, Blast_Score=242, Evalue=5e-64,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=33.7078651685393, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI21357415, Length=410, Percent_Identity=29.0243902439024, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281366494, Length=229, Percent_Identity=27.9475982532751, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667139, Length=229, Percent_Identity=27.9475982532751, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667143, Length=229, Percent_Identity=27.9475982532751, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =4.1.1.64 [H]

Molecular weight: Translated: 46676; Mature: 46544

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTQQQLLSDRARLLGPNVSTFYNDPVHIVKGDGVWLWEAEGRKYLDCYNNVPHVGHCN
CCCHHHHHHHHHHHHCCCCHHHEECCCEEEEECCCEEEECCCCCCHHHHHCCCCCCCCCC
PRVVDAICQQASTLNTHTRYLHDGILDYVEALTATMAPSLNTAILTCTGSEANDIALRTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEH
EAVTGKRGIIATDATYHGNTALVSQLSRSNVPAVGFGLGQYVRFVDAPDSYRTPDHDGQI
HHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEECCHHHHHEEECCCCCCCCCCCCCCE
FAASVAHQIAAWEEDGTGFAALIICPYMLNEGFPDHPDGWLKPTADVVRKAGGLLICDEV
EHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEHHH
QSGFGRTGTHMWAHEKMGVVPDIMTLGKPMANGHPVGGVVANSDLIATFREGYRYFNTFG
HCCCCCCCCCEEHHCCCCCCHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCC
GNPVSCAAAMAVLEELQEADLIANAKCVGDHARRRLLTLREKHDVIGDVRGSGLIFGAEL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHH
VLDRTSKAPASGYTDQIINEMRHRGILHSKLGRHKNTLKIRPPMPFSVEHVDLLLDTLDE
EEECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHH
VLSHVPLSP
HHHHCCCCC
>Mature Secondary Structure 
ARTQQQLLSDRARLLGPNVSTFYNDPVHIVKGDGVWLWEAEGRKYLDCYNNVPHVGHCN
CCHHHHHHHHHHHHCCCCHHHEECCCEEEEECCCEEEECCCCCCHHHHHCCCCCCCCCC
PRVVDAICQQASTLNTHTRYLHDGILDYVEALTATMAPSLNTAILTCTGSEANDIALRTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEH
EAVTGKRGIIATDATYHGNTALVSQLSRSNVPAVGFGLGQYVRFVDAPDSYRTPDHDGQI
HHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEECCHHHHHEEECCCCCCCCCCCCCCE
FAASVAHQIAAWEEDGTGFAALIICPYMLNEGFPDHPDGWLKPTADVVRKAGGLLICDEV
EHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEHHH
QSGFGRTGTHMWAHEKMGVVPDIMTLGKPMANGHPVGGVVANSDLIATFREGYRYFNTFG
HCCCCCCCCCEEHHCCCCCCHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCC
GNPVSCAAAMAVLEELQEADLIANAKCVGDHARRRLLTLREKHDVIGDVRGSGLIFGAEL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHH
VLDRTSKAPASGYTDQIINEMRHRGILHSKLGRHKNTLKIRPPMPFSVEHVDLLLDTLDE
EEECCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHH
VLSHVPLSP
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180928; 8342040; 7947767; 7799433; 10556038 [H]