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The map label for this gene is codA [H]

Identifier: 89053797

GI number: 89053797

Start: 1265409

End: 1266704

Strand: Reverse

Name: codA [H]

Synonym: Jann_1306

Alternate gene names: 89053797

Gene position: 1266704-1265409 (Counterclockwise)

Preceding gene: 89053798

Following gene: 89053796

Centisome position: 29.34

GC content: 62.19

Gene sequence:

>1296_bases
TTGCTAGATTTGATTTTGAGACAGGCTCGGTTACCCGATGGGCAGGGGCCTGTGGATATTGGGGTCGCTGCCGAAAAGAT
TGCCGTGATCGCGCCGCAGATCAACGCTGAGGCCCACGCGGAATTGGATGTTGCGGGCCGTCTGGTCTCGCCCCCGTTCA
CCGATCCGCATTTTCATATGGATGCCACACTGAGTCTCGGGTCCCCGAGGTTGAATGTGTCGGGGACCTTGCTGGAGGGG
ATTGCCCTTTGGGGCGAGTTGAAACCATTGCTCACGCCTGAGGCCGTCATGGAACGTGCCTTGCGGTATTGCGATCTGGC
GGTGTCTCAAGGCCTTTTGTCGATCCGCAGCCATGTCGACGTCTGTGATGATAGCCTGACGGCGGTTGAAGCGCTGATCG
AGGTCCGCAAGATCGTGGCGCCGTACATTGACTTGCAACTGGTGGCCTTCCCGCAAGATGGTCTCTACCGGTCTGCCACG
GCGGAAGCGAACCTGCTGCGTGCCCTTCACATGGGGGTCGATGTGGTGGGCGGCATCCCGCATTTTGAACGGACGATGGA
AGACGGCGCGCGGTCCGTCGTGCGCCTGTGCGAGATCGCGGCAGAGCGTGGCCTGATGCTGGACCTGCATTGCGACGAAA
GTGATGATCCGATGTCCCGCCATGTCGAGACGCTCGCGGCGGAAACCACCCGCTTGGGTCTTGGGAGCCGCGTGACCGCC
AGCCACGTCACTGCGATGCACTCCTATGACAATTACTACGCCAGCAAGCTGATACCGCTGATCGCGGAGTCGGGGATGAA
CATCATCCCCAACCCACTGATAAACATCACGCTTCAGGGCCGCTCTGACACGTATCCCAAGCGTCGGGGCCTCACCCGCG
TGCCGGAATTGCGCGCGGCGGGTGTGAACGTGGCTTTCGGGCAGGATTGCACGATGGACCCCTGGTATTCGCTGGGGTCA
GGCGACATGCTGGACGTGGCGCATATGGGCGTCCATGCCGTGCCGATGACGTCTCGCGAAGCGATGGACTGGGCCTTCAC
CTCTGTCACCGTAAACGGCGCGCGCGCCATGGGTCTGCCCGATCCGACGATCCGCGAAGGCGGCCCGGCCAATATGGTCG
TCCTGCAAGCCCGCGACCCGATTGAGGCTGTGCGGCTGCGGGCCACACGGCTCGCCGTCATCAAACACGGCAAGATCATC
GCGCGCACCGATCCCCGGCGTGCGCGGCTTACCTTGCCGGACCGCCCCGAAACGCTTGATCCAGCGGATTACCCGCCGAC
AACCCAAGATCAATGA

Upstream 100 bases:

>100_bases
CCGATTTTTATTCACTTGATGCTTCTTTTGTCAGGTCGTGCATTTAGCCAGATGACTCGTCAGAATTTTACCATATGGTA
AGGAAATTGGGGGAAGCGTT

Downstream 100 bases:

>100_bases
CAACAGCCATCAACACGAGAGGACCTTCCATGACGCTTACATCCAATCGCCGACAGCTTCTGATCGGCGCCGCCGCCACG
CTCGCCCTGCCCGCCTACAT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MLDLILRQARLPDGQGPVDIGVAAEKIAVIAPQINAEAHAELDVAGRLVSPPFTDPHFHMDATLSLGSPRLNVSGTLLEG
IALWGELKPLLTPEAVMERALRYCDLAVSQGLLSIRSHVDVCDDSLTAVEALIEVRKIVAPYIDLQLVAFPQDGLYRSAT
AEANLLRALHMGVDVVGGIPHFERTMEDGARSVVRLCEIAAERGLMLDLHCDESDDPMSRHVETLAAETTRLGLGSRVTA
SHVTAMHSYDNYYASKLIPLIAESGMNIIPNPLINITLQGRSDTYPKRRGLTRVPELRAAGVNVAFGQDCTMDPWYSLGS
GDMLDVAHMGVHAVPMTSREAMDWAFTSVTVNGARAMGLPDPTIREGGPANMVVLQARDPIEAVRLRATRLAVIKHGKII
ARTDPRRARLTLPDRPETLDPADYPPTTQDQ

Sequences:

>Translated_431_residues
MLDLILRQARLPDGQGPVDIGVAAEKIAVIAPQINAEAHAELDVAGRLVSPPFTDPHFHMDATLSLGSPRLNVSGTLLEG
IALWGELKPLLTPEAVMERALRYCDLAVSQGLLSIRSHVDVCDDSLTAVEALIEVRKIVAPYIDLQLVAFPQDGLYRSAT
AEANLLRALHMGVDVVGGIPHFERTMEDGARSVVRLCEIAAERGLMLDLHCDESDDPMSRHVETLAAETTRLGLGSRVTA
SHVTAMHSYDNYYASKLIPLIAESGMNIIPNPLINITLQGRSDTYPKRRGLTRVPELRAAGVNVAFGQDCTMDPWYSLGS
GDMLDVAHMGVHAVPMTSREAMDWAFTSVTVNGARAMGLPDPTIREGGPANMVVLQARDPIEAVRLRATRLAVIKHGKII
ARTDPRRARLTLPDRPETLDPADYPPTTQDQ
>Mature_431_residues
MLDLILRQARLPDGQGPVDIGVAAEKIAVIAPQINAEAHAELDVAGRLVSPPFTDPHFHMDATLSLGSPRLNVSGTLLEG
IALWGELKPLLTPEAVMERALRYCDLAVSQGLLSIRSHVDVCDDSLTAVEALIEVRKIVAPYIDLQLVAFPQDGLYRSAT
AEANLLRALHMGVDVVGGIPHFERTMEDGARSVVRLCEIAAERGLMLDLHCDESDDPMSRHVETLAAETTRLGLGSRVTA
SHVTAMHSYDNYYASKLIPLIAESGMNIIPNPLINITLQGRSDTYPKRRGLTRVPELRAAGVNVAFGQDCTMDPWYSLGS
GDMLDVAHMGVHAVPMTSREAMDWAFTSVTVNGARAMGLPDPTIREGGPANMVVLQARDPIEAVRLRATRLAVIKHGKII
ARTDPRRARLTLPDRPETLDPADYPPTTQDQ

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=414, Percent_Identity=44.9275362318841, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1786517, Length=299, Percent_Identity=27.0903010033445, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46836; Mature: 46836

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLILRQARLPDGQGPVDIGVAAEKIAVIAPQINAEAHAELDVAGRLVSPPFTDPHFHM
CHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCHHCCCEECCCCCCCCCEEE
DATLSLGSPRLNVSGTLLEGIALWGELKPLLTPEAVMERALRYCDLAVSQGLLSIRSHVD
EEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCDDSLTAVEALIEVRKIVAPYIDLQLVAFPQDGLYRSATAEANLLRALHMGVDVVGGIP
HCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHCCCCC
HFERTMEDGARSVVRLCEIAAERGLMLDLHCDESDDPMSRHVETLAAETTRLGLGSRVTA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
SHVTAMHSYDNYYASKLIPLIAESGMNIIPNPLINITLQGRSDTYPKRRGLTRVPELRAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCHHHC
GVNVAFGQDCTMDPWYSLGSGDMLDVAHMGVHAVPMTSREAMDWAFTSVTVNGARAMGLP
CCEEEECCCCCCCCCCCCCCCCEEHHHHCCEEEECCCCCHHHCEEEEEEEECCEEECCCC
DPTIREGGPANMVVLQARDPIEAVRLRATRLAVIKHGKIIARTDPRRARLTLPDRPETLD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEEECCEEEEECCCCCEEEECCCCCCCCC
PADYPPTTQDQ
CCCCCCCCCCC
>Mature Secondary Structure
MLDLILRQARLPDGQGPVDIGVAAEKIAVIAPQINAEAHAELDVAGRLVSPPFTDPHFHM
CHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCHHCCCEECCCCCCCCCEEE
DATLSLGSPRLNVSGTLLEGIALWGELKPLLTPEAVMERALRYCDLAVSQGLLSIRSHVD
EEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCDDSLTAVEALIEVRKIVAPYIDLQLVAFPQDGLYRSATAEANLLRALHMGVDVVGGIP
HCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHCCCCC
HFERTMEDGARSVVRLCEIAAERGLMLDLHCDESDDPMSRHVETLAAETTRLGLGSRVTA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
SHVTAMHSYDNYYASKLIPLIAESGMNIIPNPLINITLQGRSDTYPKRRGLTRVPELRAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCHHHC
GVNVAFGQDCTMDPWYSLGSGDMLDVAHMGVHAVPMTSREAMDWAFTSVTVNGARAMGLP
CCEEEECCCCCCCCCCCCCCCCEEHHHHCCEEEECCCCCHHHCEEEEEEEECCEEECCCC
DPTIREGGPANMVVLQARDPIEAVRLRATRLAVIKHGKIIARTDPRRARLTLPDRPETLD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEEECCEEEEECCCCCEEEECCCCCCCCC
PADYPPTTQDQ
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]