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The map label for this gene is aglR [H]

Identifier: 89053773

GI number: 89053773

Start: 1242520

End: 1243578

Strand: Direct

Name: aglR [H]

Synonym: Jann_1282

Alternate gene names: 89053773

Gene position: 1242520-1243578 (Clockwise)

Preceding gene: 89053772

Following gene: 89053774

Centisome position: 28.78

GC content: 60.34

Gene sequence:

>1059_bases
GTGGCAGCGCTTGCTCAACTGACGGAGCGAACCGCGCGAGATCGTGTTACGATTTCGCACATGGCGGATGCTCTCGGCGT
GACCAAGTCCACTGTGTCGCGCGCGATGAACGGCTACCCTGACATCTCCGAAGCGACACAGTTGCGGGTCAAGCGCATGG
CCGAAAAAATGGGCTATCAGCCCCTTAGTCATGCGCAGGCGATCAAGACGGGGCGGGCGCGTTCCCTCGGCCTCGTGCTT
CAGTTTTCAGACCACGACGCCCAACGTCCGTTTCTGGCGGAGTTTCTTGCCGGGTTGTCGGCCGGAGCACATACCGATGG
CTGGACGTTAACGGTTGCAGCGGCCGACGGCCACGATGAGTTGATCGAAACGTTTCGTGCCATATTGCGCGACGGAAAGG
CCGATGGGTTTATTCTGCCACGGGCTATGTCGACTGATCCCCGGGTGTATCTGCTGCGAGATGCGGGCGTTCCATTCGTT
CTGTTTGGACGGCAAGACAAAGAAGAGGGCTGCGCCTGGTTCGACGTTCTGGGCGAAGAGGCGATGTGCGATGCTGTGCT
GCATTTAGCAACGCTGGGCCATCGCCGCATCGGGTTTATCAATGGTGGTCTGCAATATGCCTATGCCCGTCTGCGGGCTG
CTGGTTTCGCGGATGGGATGCAGATTGCCGGGCTTGAGATGGACGACAGCCTCATCGCTGATGATGCGATGACGATGGAG
AGCGGAGCAGTGGCGGCGGCGCGAATTCTCGACACGACCAACCCGCCGACTGCGTTGGTCTGCGCCGTTGATTTCGCCGC
TCTTGGCGCATACCGCGCTGCCGCAGACAGGGGGATAATCATTGGCCGGGATCTGTCGATCATTGGCTATGACGGCATCC
CTGAGGGGGCCTTTGCCCACCCCCCGCTGACAACATTCGCGGTGGATAACCGTGCTGCTGGTTTCGCGCTGGCAACGTTA
CTGATCCAGCGCATCAAGGGCGAACCCCTCGAAACACTGCGGAGACTAGTTCCCGCCACCTTTGTGGAACGCGCGTCCAC
GGGACCAGCCAAGGCATGA

Upstream 100 bases:

>100_bases
TGAGGAGGGGTACCGGTCTGCCCGCGTTGAAACTCTAAAACAAAACTCTTGCCGAAACCGGTTTCGGTTCGCACTCTCGA
TTTTGGGAGGACAAGTTTCG

Downstream 100 bases:

>100_bases
AAGCAACTGGTTTAAAAATGACTTCAATGGGAGGAAGATAAATGAAACTCAAGACAAAATCACTCATGCGGACCGGCGTG
GCGATGGCGTTGATCCTGTC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAALAQLTERTARDRVTISHMADALGVTKSTVSRAMNGYPDISEATQLRVKRMAEKMGYQPLSHAQAIKTGRARSLGLVL
QFSDHDAQRPFLAEFLAGLSAGAHTDGWTLTVAAADGHDELIETFRAILRDGKADGFILPRAMSTDPRVYLLRDAGVPFV
LFGRQDKEEGCAWFDVLGEEAMCDAVLHLATLGHRRIGFINGGLQYAYARLRAAGFADGMQIAGLEMDDSLIADDAMTME
SGAVAAARILDTTNPPTALVCAVDFAALGAYRAAADRGIIIGRDLSIIGYDGIPEGAFAHPPLTTFAVDNRAAGFALATL
LIQRIKGEPLETLRRLVPATFVERASTGPAKA

Sequences:

>Translated_352_residues
MAALAQLTERTARDRVTISHMADALGVTKSTVSRAMNGYPDISEATQLRVKRMAEKMGYQPLSHAQAIKTGRARSLGLVL
QFSDHDAQRPFLAEFLAGLSAGAHTDGWTLTVAAADGHDELIETFRAILRDGKADGFILPRAMSTDPRVYLLRDAGVPFV
LFGRQDKEEGCAWFDVLGEEAMCDAVLHLATLGHRRIGFINGGLQYAYARLRAAGFADGMQIAGLEMDDSLIADDAMTME
SGAVAAARILDTTNPPTALVCAVDFAALGAYRAAADRGIIIGRDLSIIGYDGIPEGAFAHPPLTTFAVDNRAAGFALATL
LIQRIKGEPLETLRRLVPATFVERASTGPAKA
>Mature_351_residues
AALAQLTERTARDRVTISHMADALGVTKSTVSRAMNGYPDISEATQLRVKRMAEKMGYQPLSHAQAIKTGRARSLGLVLQ
FSDHDAQRPFLAEFLAGLSAGAHTDGWTLTVAAADGHDELIETFRAILRDGKADGFILPRAMSTDPRVYLLRDAGVPFVL
FGRQDKEEGCAWFDVLGEEAMCDAVLHLATLGHRRIGFINGGLQYAYARLRAAGFADGMQIAGLEMDDSLIADDAMTMES
GAVAAARILDTTNPPTALVCAVDFAALGAYRAAADRGIIIGRDLSIIGYDGIPEGAFAHPPLTTFAVDNRAAGFALATLL
IQRIKGEPLETLRRLVPATFVERASTGPAKA

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=332, Percent_Identity=28.9156626506024, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787948, Length=340, Percent_Identity=27.3529411764706, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=26.6467065868263, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1789068, Length=316, Percent_Identity=28.1645569620253, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=23.8993710691824, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1786540, Length=353, Percent_Identity=26.0623229461756, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789202, Length=334, Percent_Identity=26.0479041916168, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787906, Length=343, Percent_Identity=24.7813411078717, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789456, Length=336, Percent_Identity=25.297619047619, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788474, Length=293, Percent_Identity=25.5972696245734, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=23.125, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790715, Length=324, Percent_Identity=23.7654320987654, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37643; Mature: 37512

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALAQLTERTARDRVTISHMADALGVTKSTVSRAMNGYPDISEATQLRVKRMAEKMGYQ
CCHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
PLSHAQAIKTGRARSLGLVLQFSDHDAQRPFLAEFLAGLSAGAHTDGWTLTVAAADGHDE
CHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHH
LIETFRAILRDGKADGFILPRAMSTDPRVYLLRDAGVPFVLFGRQDKEEGCAWFDVLGEE
HHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHCCH
AMCDAVLHLATLGHRRIGFINGGLQYAYARLRAAGFADGMQIAGLEMDDSLIADDAMTME
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHHCCHHHHC
SGAVAAARILDTTNPPTALVCAVDFAALGAYRAAADRGIIIGRDLSIIGYDGIPEGAFAH
CCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCCCCC
PPLTTFAVDNRAAGFALATLLIQRIKGEPLETLRRLVPATFVERASTGPAKA
CCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AALAQLTERTARDRVTISHMADALGVTKSTVSRAMNGYPDISEATQLRVKRMAEKMGYQ
CHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
PLSHAQAIKTGRARSLGLVLQFSDHDAQRPFLAEFLAGLSAGAHTDGWTLTVAAADGHDE
CHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHH
LIETFRAILRDGKADGFILPRAMSTDPRVYLLRDAGVPFVLFGRQDKEEGCAWFDVLGEE
HHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHHHCCH
AMCDAVLHLATLGHRRIGFINGGLQYAYARLRAAGFADGMQIAGLEMDDSLIADDAMTME
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCCCHHHCCHHHHC
SGAVAAARILDTTNPPTALVCAVDFAALGAYRAAADRGIIIGRDLSIIGYDGIPEGAFAH
CCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCCCCC
PPLTTFAVDNRAAGFALATLLIQRIKGEPLETLRRLVPATFVERASTGPAKA
CCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]