Click here to switch to the map view.

The map label for this gene is gltC [H]

Identifier: 89053756

GI number: 89053756

Start: 1225355

End: 1226239

Strand: Direct

Name: gltC [H]

Synonym: Jann_1265

Alternate gene names: 89053756

Gene position: 1225355-1226239 (Clockwise)

Preceding gene: 89053754

Following gene: 89053757

Centisome position: 28.38

GC content: 64.63

Gene sequence:

>885_bases
ATGCAAACGCGTGCCCTAAAGACCCTTTCAAAAATTGCCCAGGTCGGGTCCTTCGTCCAATCGGCGGAGCAGTTGGGCAT
GACGCTGTCGGCGGTGTCGATGCAGATGAAGGCGCTGGAGGCAGAATTGGGCGTGGCGCTGTTTGACCGATCCGTGCGTC
CGCCGCGCCTGACCCCCGTGGCCGCCGCTGTGGTGACCGAGGCGCAGGCGCTGCTTCTGTGGGAGGATCGCCTGCTGGAG
TTGTGCCGCCCCAGTGACACGTTGGTGGGCCAGTATAAGCTGGGCTTTGTCACCACCGCCGCCGTGCGCCTGCTGCCGGA
TTTCCTGAAGACGGCGCAGGATATGGCCCCCATGGCCAGCTTTGAGGTCGAAACCGGTCTGTCGGCCACCCTGCAAGACA
AGGTGATGACCGGTCAGATTGATGCGGCGGTCGTGACCGATGCGGACGGTCTGCCGCCACGCCTGTCGTCCCGGCTGCTA
CGGACAGAGCCGTTCGTGTTTGCCGCCCATGGTGATCTGATGGCGGATGGAATTGAGGGGCTGATGACCCGTGACACGTT
CTTTCATTTCATGCCGGATACGGGCATTGGCAAACTCATTGCCCGCGCGATGTTGCAGCAAAACCGCCCCGGAGCGGCGC
GCACCATCGTTCTGGATGATCTGGAAGCGATCATGGAATGTGTCGCCAGCGGCCTTGGGTTCACCCTGCTGCCGGTCCCG
GATGTGGAGCGATACCTGACCCGGCAGGTCCGGACGGTGCCAGCGCCCGCGGGGTTGGAGCGCAAGCTGGTGCTGGCCGT
GCTGCGCGACGGCGGGATGGCCCCCCGGGAGGCCGCGCTTGGCGCACTTTTTGACGCGGCAGTTGATCCCACGGGCCCGT
CGTGA

Upstream 100 bases:

>100_bases
TCCGGTGGTGGTCACAGGGTCGTGATGACTTGACCATACAGACGCGGCACTTCATTACCATGGAATAAGATTTGATATTA
AGTTCAGCGTCCATGAAGAT

Downstream 100 bases:

>100_bases
CGGGCGATCAGGGCGCTGAGATCGGACCGGCTTTGGGGTGGTGGGGCTGCGGCAGGCGGCGAGGGACCCCGGTTCACGCG
TGCAATGGACCTGTGATCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MQTRALKTLSKIAQVGSFVQSAEQLGMTLSAVSMQMKALEAELGVALFDRSVRPPRLTPVAAAVVTEAQALLLWEDRLLE
LCRPSDTLVGQYKLGFVTTAAVRLLPDFLKTAQDMAPMASFEVETGLSATLQDKVMTGQIDAAVVTDADGLPPRLSSRLL
RTEPFVFAAHGDLMADGIEGLMTRDTFFHFMPDTGIGKLIARAMLQQNRPGAARTIVLDDLEAIMECVASGLGFTLLPVP
DVERYLTRQVRTVPAPAGLERKLVLAVLRDGGMAPREAALGALFDAAVDPTGPS

Sequences:

>Translated_294_residues
MQTRALKTLSKIAQVGSFVQSAEQLGMTLSAVSMQMKALEAELGVALFDRSVRPPRLTPVAAAVVTEAQALLLWEDRLLE
LCRPSDTLVGQYKLGFVTTAAVRLLPDFLKTAQDMAPMASFEVETGLSATLQDKVMTGQIDAAVVTDADGLPPRLSSRLL
RTEPFVFAAHGDLMADGIEGLMTRDTFFHFMPDTGIGKLIARAMLQQNRPGAARTIVLDDLEAIMECVASGLGFTLLPVP
DVERYLTRQVRTVPAPAGLERKLVLAVLRDGGMAPREAALGALFDAAVDPTGPS
>Mature_294_residues
MQTRALKTLSKIAQVGSFVQSAEQLGMTLSAVSMQMKALEAELGVALFDRSVRPPRLTPVAAAVVTEAQALLLWEDRLLE
LCRPSDTLVGQYKLGFVTTAAVRLLPDFLKTAQDMAPMASFEVETGLSATLQDKVMTGQIDAAVVTDADGLPPRLSSRLL
RTEPFVFAAHGDLMADGIEGLMTRDTFFHFMPDTGIGKLIARAMLQQNRPGAARTIVLDDLEAIMECVASGLGFTLLPVP
DVERYLTRQVRTVPAPAGLERKLVLAVLRDGGMAPREAALGALFDAAVDPTGPS

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787806, Length=245, Percent_Identity=25.7142857142857, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31520; Mature: 31520

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTRALKTLSKIAQVGSFVQSAEQLGMTLSAVSMQMKALEAELGVALFDRSVRPPRLTPV
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AAAVVTEAQALLLWEDRLLELCRPSDTLVGQYKLGFVTTAAVRLLPDFLKTAQDMAPMAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEVETGLSATLQDKVMTGQIDAAVVTDADGLPPRLSSRLLRTEPFVFAAHGDLMADGIEG
HHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHH
LMTRDTFFHFMPDTGIGKLIARAMLQQNRPGAARTIVLDDLEAIMECVASGLGFTLLPVP
HHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEECCC
DVERYLTRQVRTVPAPAGLERKLVLAVLRDGGMAPREAALGALFDAAVDPTGPS
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQTRALKTLSKIAQVGSFVQSAEQLGMTLSAVSMQMKALEAELGVALFDRSVRPPRLTPV
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AAAVVTEAQALLLWEDRLLELCRPSDTLVGQYKLGFVTTAAVRLLPDFLKTAQDMAPMAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEVETGLSATLQDKVMTGQIDAAVVTDADGLPPRLSSRLLRTEPFVFAAHGDLMADGIEG
HHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHH
LMTRDTFFHFMPDTGIGKLIARAMLQQNRPGAARTIVLDDLEAIMECVASGLGFTLLPVP
HHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEECCC
DVERYLTRQVRTVPAPAGLERKLVLAVLRDGGMAPREAALGALFDAAVDPTGPS
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]