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The map label for this gene is xerC

Identifier: 89053521

GI number: 89053521

Start: 982398

End: 983321

Strand: Reverse

Name: xerC

Synonym: Jann_1030

Alternate gene names: 89053521

Gene position: 983321-982398 (Counterclockwise)

Preceding gene: 89053522

Following gene: 89053520

Centisome position: 22.77

GC content: 67.86

Gene sequence:

>924_bases
ATGTCACTCGCGCTGACCCCGGCGGTGCGTGATCTGTTGGCGGGCTGGCTGACCCACCTGCGCGGTGTGCGCGGGCGGGC
GGAAGCCACGCTGACGGCTTATGGCGCGGATGTGGGCGAATTCCTTGCATTCCAGGCGGACCATTTGGGTGGCTCCCCCG
GCCCTGCCGCGTTGCGGACGCTGCAAACCCGTGACCTGCGCGCGTGGATGTCGTCGCAACGGGCGCGGGATGTGGGCGCG
CGGTCCTTGGCGCGCCGCCTCTCTGCCGTGAAGGCCTTCTACAATTGGTGGGCCGAACGCGATGGCTTCGACGCCACTGC
CGTTTTGTCCATGCGTGCGCCCAAACACACCCGCCGCCTGCCCCGCCCCCTGACAGAAGTGGGCGCGAAAGACATGATCG
CAGGGCTTGCCGATCAGGACGACCGCGATTGGGTGCAGGCCAGGGACATGGCCGTCGTCACATTGCTCTACGGCTGCGGA
TTGCGGATATCGGAAGCGCTTGGCCTCACCGCCGATCTGCTGCCCCTGCCCGGCATTCTGCGCATCACCGGCAAAGGCGG
GAAGGAGCGGGAGGTTCCTGTTCTGCCCGCAGCCCAAGACGCCTGCGCACGATACGCCCAACTCTGCCCCCACGACCTTG
CCCCGGGAACCCCGCTGTTTCGGGCGATCCGGGGCGGCGCGCTCGGCCCCCGCGCGGTCGCCAAGGTGATGGAGAAAACT
CGTCTACAACTTGGCCTGCCCGCGACCGCCACCCCCCACGCGATGCGGCATTCCTTTGCCACGCACCTTCTGGACGCGGG
CGGCGATCTGCGCGCCATTCAGGAGCTTTTGGGCCACGCGTCCCTTTCCACCACCCAGGCCTATACCGCCGTCGATACCG
CCCGCCTGATGGAAGTCTACGCGAACGCGCACCCCAAGGCCTGA

Upstream 100 bases:

>100_bases
GAAGATCCGCACCAGTTCCGCCCCTCGCAAGGCACGGATCTGCTGACGTTCTTCGCGGGCGTGTTTGAACGCCTCATGCG
CGGCTGGCTGGATTAGGCCC

Downstream 100 bases:

>100_bases
AGGAGTGCGGGCCACAGCCCCGACACGATGCCGGTCAAGAGCGGTTGCAAACGCCCCATATTACAGGCATCGAAGCGCCC
ATGCGATTTAGAGCTTACTC

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSLALTPAVRDLLAGWLTHLRGVRGRAEATLTAYGADVGEFLAFQADHLGGSPGPAALRTLQTRDLRAWMSSQRARDVGA
RSLARRLSAVKAFYNWWAERDGFDATAVLSMRAPKHTRRLPRPLTEVGAKDMIAGLADQDDRDWVQARDMAVVTLLYGCG
LRISEALGLTADLLPLPGILRITGKGGKEREVPVLPAAQDACARYAQLCPHDLAPGTPLFRAIRGGALGPRAVAKVMEKT
RLQLGLPATATPHAMRHSFATHLLDAGGDLRAIQELLGHASLSTTQAYTAVDTARLMEVYANAHPKA

Sequences:

>Translated_307_residues
MSLALTPAVRDLLAGWLTHLRGVRGRAEATLTAYGADVGEFLAFQADHLGGSPGPAALRTLQTRDLRAWMSSQRARDVGA
RSLARRLSAVKAFYNWWAERDGFDATAVLSMRAPKHTRRLPRPLTEVGAKDMIAGLADQDDRDWVQARDMAVVTLLYGCG
LRISEALGLTADLLPLPGILRITGKGGKEREVPVLPAAQDACARYAQLCPHDLAPGTPLFRAIRGGALGPRAVAKVMEKT
RLQLGLPATATPHAMRHSFATHLLDAGGDLRAIQELLGHASLSTTQAYTAVDTARLMEVYANAHPKA
>Mature_306_residues
SLALTPAVRDLLAGWLTHLRGVRGRAEATLTAYGADVGEFLAFQADHLGGSPGPAALRTLQTRDLRAWMSSQRARDVGAR
SLARRLSAVKAFYNWWAERDGFDATAVLSMRAPKHTRRLPRPLTEVGAKDMIAGLADQDDRDWVQARDMAVVTLLYGCGL
RISEALGLTADLLPLPGILRITGKGGKEREVPVLPAAQDACARYAQLCPHDLAPGTPLFRAIRGGALGPRAVAKVMEKTR
LQLGLPATATPHAMRHSFATHLLDAGGDLRAIQELLGHASLSTTQAYTAVDTARLMEVYANAHPKA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=293, Percent_Identity=34.8122866894198, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789261, Length=300, Percent_Identity=35.6666666666667, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33018; Mature: 32887

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLALTPAVRDLLAGWLTHLRGVRGRAEATLTAYGADVGEFLAFQADHLGGSPGPAALRT
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHH
LQTRDLRAWMSSQRARDVGARSLARRLSAVKAFYNWWAERDGFDATAVLSMRAPKHTRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHC
PRPLTEVGAKDMIAGLADQDDRDWVQARDMAVVTLLYGCGLRISEALGLTADLLPLPGIL
CCCHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCEE
RITGKGGKEREVPVLPAAQDACARYAQLCPHDLAPGTPLFRAIRGGALGPRAVAKVMEKT
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHH
RLQLGLPATATPHAMRHSFATHLLDAGGDLRAIQELLGHASLSTTQAYTAVDTARLMEVY
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ANAHPKA
HCCCCCC
>Mature Secondary Structure 
SLALTPAVRDLLAGWLTHLRGVRGRAEATLTAYGADVGEFLAFQADHLGGSPGPAALRT
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHH
LQTRDLRAWMSSQRARDVGARSLARRLSAVKAFYNWWAERDGFDATAVLSMRAPKHTRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHC
PRPLTEVGAKDMIAGLADQDDRDWVQARDMAVVTLLYGCGLRISEALGLTADLLPLPGIL
CCCHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCEE
RITGKGGKEREVPVLPAAQDACARYAQLCPHDLAPGTPLFRAIRGGALGPRAVAKVMEKT
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHH
RLQLGLPATATPHAMRHSFATHLLDAGGDLRAIQELLGHASLSTTQAYTAVDTARLMEVY
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ANAHPKA
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]