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The map label for this gene is bphB [H]

Identifier: 89053337

GI number: 89053337

Start: 801135

End: 801878

Strand: Reverse

Name: bphB [H]

Synonym: Jann_0846

Alternate gene names: 89053337

Gene position: 801878-801135 (Counterclockwise)

Preceding gene: 89053338

Following gene: 89053333

Centisome position: 18.57

GC content: 63.98

Gene sequence:

>744_bases
ATGACGCAAAATCCCGTGAAAACCATTCTGATCACCGGCGCAAGCTCTGGCATTGGCCGGGCCACGGCGGAGGTGTTTCT
CGCCTCCGGCTGGAACGTGGCCCTCCTCGCGCGCCGCCGCGCGCTCCTCGCAGAGGTGGCCTCCGGCCACGACAACGCCC
TCGCCCTGCCGGGTGACGTGACCCAATTGGCGGATGTCGAGGCTGCTATCGCGGCCATCGTTGCCAAATGGGGCCGCCTG
GACGCCGTCTTCAACAACGCGGGCATCTTCACGCCCCAGGGCACCATCGACGAAATCGACGTCGCGGATTGGCATCAAAG
TCTCTCGGTCAACCTCACCGGCATGTTCAACACCGCCCGCGTGGCCTTCGCCCAGATGCGTGCGCAAGACCCTCAAGGCG
GACGGATCATCAACAATGGCTCGCTCTCGGCGCATTCCCCGCGCGAAGGCTCCATTTGCTACACGACCACCAAACACGGC
ATCACCGGCCTGACGAAAACCCTCAGCCTCGATGGCCGCCCGTTTGGCATCGCGGCGGGCCAGATTGACATCGGAAATGC
CCGCACGGACCTCGTCGACGCCTTGAACGAGCGCCGCATCAAGGACGGCAAGCCCCTGATGGATATGATGAATGTCGCAG
ACGCGGCGCAATCGGTCCTGCATATGGCCAACATGCCGCCGTCGGCCAACGTCCTCTTCCAGACCGTCCTGGCCACCAAC
ATGCCCTATGTCGGGCGCGGTTGA

Upstream 100 bases:

>100_bases
TGACCGTCAAAGCCGCACCGCTGGAGTTGGAGGCGGAAGAAGACGCGGACACCTCTACGATGTAGTTACAGAATAACTAC
AGGAAAGTTACGCATTCATT

Downstream 100 bases:

>100_bases
CCGAGGGCGTCCCGCAGTTCCATCTGGGCCATTACAACTCCTCGGGGGTACGCGTCTTTTTCCCCGAAAAAGCGGCGTGA
GGGGGGCGGCCCCCGTGCCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase; 2,3-dihydroxy-4-phenylhexa-4,6-diene dehydrogenase; Biphenyl-2,3-dihydro-2,3-diol dehydrogenase; Biphenyl-cis-diol dehydrogenase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTQNPVKTILITGASSGIGRATAEVFLASGWNVALLARRRALLAEVASGHDNALALPGDVTQLADVEAAIAAIVAKWGRL
DAVFNNAGIFTPQGTIDEIDVADWHQSLSVNLTGMFNTARVAFAQMRAQDPQGGRIINNGSLSAHSPREGSICYTTTKHG
ITGLTKTLSLDGRPFGIAAGQIDIGNARTDLVDALNERRIKDGKPLMDMMNVADAAQSVLHMANMPPSANVLFQTVLATN
MPYVGRG

Sequences:

>Translated_247_residues
MTQNPVKTILITGASSGIGRATAEVFLASGWNVALLARRRALLAEVASGHDNALALPGDVTQLADVEAAIAAIVAKWGRL
DAVFNNAGIFTPQGTIDEIDVADWHQSLSVNLTGMFNTARVAFAQMRAQDPQGGRIINNGSLSAHSPREGSICYTTTKHG
ITGLTKTLSLDGRPFGIAAGQIDIGNARTDLVDALNERRIKDGKPLMDMMNVADAAQSVLHMANMPPSANVLFQTVLATN
MPYVGRG
>Mature_246_residues
TQNPVKTILITGASSGIGRATAEVFLASGWNVALLARRRALLAEVASGHDNALALPGDVTQLADVEAAIAAIVAKWGRLD
AVFNNAGIFTPQGTIDEIDVADWHQSLSVNLTGMFNTARVAFAQMRAQDPQGGRIINNGSLSAHSPREGSICYTTTKHGI
TGLTKTLSLDGRPFGIAAGQIDIGNARTDLVDALNERRIKDGKPLMDMMNVADAAQSVLHMANMPPSANVLFQTVLATNM
PYVGRG

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=34.1708542713568, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI83715985, Length=178, Percent_Identity=34.2696629213483, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI59889578, Length=146, Percent_Identity=33.5616438356164, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI40254992, Length=224, Percent_Identity=27.6785714285714, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI31542939, Length=172, Percent_Identity=30.8139534883721, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786812, Length=236, Percent_Identity=29.2372881355932, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788459, Length=167, Percent_Identity=30.5389221556886, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=32.4742268041237, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=31.7948717948718, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI2367175, Length=223, Percent_Identity=29.5964125560538, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=244, Percent_Identity=25.8196721311475, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=26.2096774193548, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788891, Length=229, Percent_Identity=29.2576419213974, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789057, Length=183, Percent_Identity=28.9617486338798, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=28.0612244897959, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=199, Percent_Identity=33.1658291457286, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=177, Percent_Identity=30.5084745762712, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=190, Percent_Identity=30, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=27.7227722772277, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=205, Percent_Identity=28.2926829268293, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17737361, Length=208, Percent_Identity=33.6538461538462, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=233, Percent_Identity=27.4678111587983, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007236, Length=248, Percent_Identity=29.0322580645161, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=26.8421052631579, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641232, Length=239, Percent_Identity=29.7071129707113, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI116007238, Length=178, Percent_Identity=31.4606741573034, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641388, Length=242, Percent_Identity=28.099173553719, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=188, Percent_Identity=28.7234042553192, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648693, Length=236, Percent_Identity=28.8135593220339, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355889, Length=236, Percent_Identity=28.8135593220339, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571387, Length=237, Percent_Identity=28.2700421940928, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI18859837, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI116007234, Length=249, Percent_Identity=28.1124497991968, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017711
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.56 [H]

Molecular weight: Translated: 26061; Mature: 25930

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNPVKTILITGASSGIGRATAEVFLASGWNVALLARRRALLAEVASGHDNALALPGDV
CCCCCEEEEEEECCCCCCCHHEEEEEEECCCCEEHHHHHHHHHHHHHCCCCCEEECCCCH
TQLADVEAAIAAIVAKWGRLDAVFNNAGIFTPQGTIDEIDVADWHQSLSVNLTGMFNTAR
HHHHHHHHHHHHHHHHHCCHHEEECCCCEECCCCCCCCCCHHHHHCCEEEEEEECCHHHH
VAFAQMRAQDPQGGRIINNGSLSAHSPREGSICYTTTKHGITGLTKTLSLDGRPFGIAAG
HHHHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHEEECCCCCEEEEEC
QIDIGNARTDLVDALNERRIKDGKPLMDMMNVADAAQSVLHMANMPPSANVLFQTVLATN
EEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
MPYVGRG
CCCCCCC
>Mature Secondary Structure 
TQNPVKTILITGASSGIGRATAEVFLASGWNVALLARRRALLAEVASGHDNALALPGDV
CCCCEEEEEEECCCCCCCHHEEEEEEECCCCEEHHHHHHHHHHHHHCCCCCEEECCCCH
TQLADVEAAIAAIVAKWGRLDAVFNNAGIFTPQGTIDEIDVADWHQSLSVNLTGMFNTAR
HHHHHHHHHHHHHHHHHCCHHEEECCCCEECCCCCCCCCCHHHHHCCEEEEEEECCHHHH
VAFAQMRAQDPQGGRIINNGSLSAHSPREGSICYTTTKHGITGLTKTLSLDGRPFGIAAG
HHHHHHHCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHEEECCCCCEEEEEC
QIDIGNARTDLVDALNERRIKDGKPLMDMMNVADAAQSVLHMANMPPSANVLFQTVLATN
EEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
MPYVGRG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8344527; 1569021; 9655331 [H]