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The map label for this gene is bioI [H]

Identifier: 89053168

GI number: 89053168

Start: 649494

End: 650702

Strand: Reverse

Name: bioI [H]

Synonym: Jann_0677

Alternate gene names: 89053168

Gene position: 650702-649494 (Counterclockwise)

Preceding gene: 89053170

Following gene: 89053151

Centisome position: 15.07

GC content: 62.78

Gene sequence:

>1209_bases
ATGCTGGATATCGCGCAATTCGATCTCAACCAGATTGACGCCGCATTTATCGAAGACCCCTATTCAACGCTGGCCGCGCT
GCGCCGCACCTCGCCCGTCCATCCCAACGCGGACGGCTCCGTCTACCTGACGCGCCACGATGATTGCCTGGCCACCTACC
GGTCCCGCGACATGCTGTCGGACAAGACCGAAGCGTTTGGCCAGAAGTTTGGCGAATGCCCGCTGAAGGTGCATCACACG
ACCTCTCTGATCTTCAACGATCCGCCCTATCACACTGTGGTGCGCAAGCTCATCGCGGGGGCCTTCACGCCCCGCAAACT
CAAAGAGATGGAGCGCGCGATTGAACGGATCGTCTCGCGTCTTCTGGACCGGGTGGAGGATCTGGGGGAGCTGGATGTCA
TTGCCGATTTCGGAATGATGCTGCCCACCGAGATCATCTCCATCATGCTTGGCGTGCCCGAGGCCTATCGCGCGCAGCTG
CGGGGGTATTCGACGGCCATTCTGGGCGCGCTTGACCCGGTTGTGTCTTCATCCCAGATGGAGGCGGGCAACCGCGCCGT
CGAAGAATTTGGCGCCGTCCTGGATGACCTGATCAACCACCGTCGCGCCAACCCCGATGCGGCGGCAGAGGGCGAAGTGC
TGGAATCGCTGATTTTCGGGGAACACGACGGCCGTACCCTGACCCAGGAAGAGTTGGTGCAGAACTGTATCTTCCTTCTC
AACGCGGGCCACGAGACGACAACATCGCTGGTCGGAAATGCGGTCGCAGTGTTGCTGGCCAACCCGTCCGAGCATCGCCG
CCTGATCGACGACCCCACCCTGATCGGCACTGCCGTGGAGGAGATCCTGCGCGTCGAAAGCCCGCTGCAAATCGGCAACC
GTTTGGCGGGGGAAGACATCGCCCTCCCCTCCGGCCCGACGATTCCGAAGGGTACCTACATCCACACATCCATCGCCGCC
GCCAACCGCGATCCGGAGGTCTTCGCGGACCCCGACCGCTTCGACGTGTCCCGCAAACCGAACCCGCATATCGCGTTCAT
CACGGGCATCCACGTCTGCCTCGGCGCGTCCCTGGCGCGGATGGAAGGGAAGATCGCCATTGGTGGCTTCGTCAAACGGT
TCCCAAAGCTGGCCGCGACCGGTGAGGGGGAGCGCCTTGGCCTTGCCCGGTTCAGGGGATGGACGTCGCTGCCCATCCGA
GTGCGATAG

Upstream 100 bases:

>100_bases
TGCCGCGACCCTCATCAGATTTCGCAATTGAGGGGTCGACACCCCCTTGCGACGCCCCGGCCCCGGCCCAATACTCACCC
GCGAAAAGGGAGCTTTCACG

Downstream 100 bases:

>100_bases
CGTTAGGTTGTCCGCTGCCAGTCGGCCAGTTTGGTGCCGGTCTGCGCGCAGTCCAAAAGAACCGGGCTCACCTTCCAGAT
CACCGGGTCAACCGCCTCTA

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MLDIAQFDLNQIDAAFIEDPYSTLAALRRTSPVHPNADGSVYLTRHDDCLATYRSRDMLSDKTEAFGQKFGECPLKVHHT
TSLIFNDPPYHTVVRKLIAGAFTPRKLKEMERAIERIVSRLLDRVEDLGELDVIADFGMMLPTEIISIMLGVPEAYRAQL
RGYSTAILGALDPVVSSSQMEAGNRAVEEFGAVLDDLINHRRANPDAAAEGEVLESLIFGEHDGRTLTQEELVQNCIFLL
NAGHETTTSLVGNAVAVLLANPSEHRRLIDDPTLIGTAVEEILRVESPLQIGNRLAGEDIALPSGPTIPKGTYIHTSIAA
ANRDPEVFADPDRFDVSRKPNPHIAFITGIHVCLGASLARMEGKIAIGGFVKRFPKLAATGEGERLGLARFRGWTSLPIR
VR

Sequences:

>Translated_402_residues
MLDIAQFDLNQIDAAFIEDPYSTLAALRRTSPVHPNADGSVYLTRHDDCLATYRSRDMLSDKTEAFGQKFGECPLKVHHT
TSLIFNDPPYHTVVRKLIAGAFTPRKLKEMERAIERIVSRLLDRVEDLGELDVIADFGMMLPTEIISIMLGVPEAYRAQL
RGYSTAILGALDPVVSSSQMEAGNRAVEEFGAVLDDLINHRRANPDAAAEGEVLESLIFGEHDGRTLTQEELVQNCIFLL
NAGHETTTSLVGNAVAVLLANPSEHRRLIDDPTLIGTAVEEILRVESPLQIGNRLAGEDIALPSGPTIPKGTYIHTSIAA
ANRDPEVFADPDRFDVSRKPNPHIAFITGIHVCLGASLARMEGKIAIGGFVKRFPKLAATGEGERLGLARFRGWTSLPIR
VR
>Mature_402_residues
MLDIAQFDLNQIDAAFIEDPYSTLAALRRTSPVHPNADGSVYLTRHDDCLATYRSRDMLSDKTEAFGQKFGECPLKVHHT
TSLIFNDPPYHTVVRKLIAGAFTPRKLKEMERAIERIVSRLLDRVEDLGELDVIADFGMMLPTEIISIMLGVPEAYRAQL
RGYSTAILGALDPVVSSSQMEAGNRAVEEFGAVLDDLINHRRANPDAAAEGEVLESLIFGEHDGRTLTQEELVQNCIFLL
NAGHETTTSLVGNAVAVLLANPSEHRRLIDDPTLIGTAVEEILRVESPLQIGNRLAGEDIALPSGPTIPKGTYIHTSIAA
ANRDPEVFADPDRFDVSRKPNPHIAFITGIHVCLGASLARMEGKIAIGGFVKRFPKLAATGEGERLGLARFRGWTSLPIR
VR

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Drosophila melanogaster, GI17864382, Length=208, Percent_Identity=25.9615384615385, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 44047; Mature: 44047

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIAQFDLNQIDAAFIEDPYSTLAALRRTSPVHPNADGSVYLTRHDDCLATYRSRDMLS
CCCCHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
DKTEAFGQKFGECPLKVHHTTSLIFNDPPYHTVVRKLIAGAFTPRKLKEMERAIERIVSR
HHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLDRVEDLGELDVIADFGMMLPTEIISIMLGVPEAYRAQLRGYSTAILGALDPVVSSSQM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCHHH
EAGNRAVEEFGAVLDDLINHRRANPDAAAEGEVLESLIFGEHDGRTLTQEELVQNCIFLL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
NAGHETTTSLVGNAVAVLLANPSEHRRLIDDPTLIGTAVEEILRVESPLQIGNRLAGEDI
CCCCHHHHHHHHCEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCC
ALPSGPTIPKGTYIHTSIAAANRDPEVFADPDRFDVSRKPNPHIAFITGIHVCLGASLAR
CCCCCCCCCCCCEEEEEHHHCCCCCCCEECCCCCCCCCCCCCCEEHHHHHHHHHCCHHHH
MEGKIAIGGFVKRFPKLAATGEGERLGLARFRGWTSLPIRVR
HCCCEEECHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEC
>Mature Secondary Structure
MLDIAQFDLNQIDAAFIEDPYSTLAALRRTSPVHPNADGSVYLTRHDDCLATYRSRDMLS
CCCCHHCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
DKTEAFGQKFGECPLKVHHTTSLIFNDPPYHTVVRKLIAGAFTPRKLKEMERAIERIVSR
HHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LLDRVEDLGELDVIADFGMMLPTEIISIMLGVPEAYRAQLRGYSTAILGALDPVVSSSQM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCHHH
EAGNRAVEEFGAVLDDLINHRRANPDAAAEGEVLESLIFGEHDGRTLTQEELVQNCIFLL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
NAGHETTTSLVGNAVAVLLANPSEHRRLIDDPTLIGTAVEEILRVESPLQIGNRLAGEDI
CCCCHHHHHHHHCEEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCC
ALPSGPTIPKGTYIHTSIAAANRDPEVFADPDRFDVSRKPNPHIAFITGIHVCLGASLAR
CCCCCCCCCCCCEEEEEHHHCCCCCCCEECCCCCCCCCCCCCCEEHHHHHHHHHCCHHHH
MEGKIAIGGFVKRFPKLAATGEGERLGLARFRGWTSLPIRVR
HCCCEEECHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]