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The map label for this gene is argB

Identifier: 89053124

GI number: 89053124

Start: 605486

End: 606343

Strand: Reverse

Name: argB

Synonym: Jann_0633

Alternate gene names: 89053124

Gene position: 606343-605486 (Counterclockwise)

Preceding gene: 89053125

Following gene: 89053123

Centisome position: 14.04

GC content: 64.22

Gene sequence:

>858_bases
ATGAAAACCCAGATGACCCGCGACAATCTTGCGACCGCCCGGACCCTGTCCGAAGCCCTGCCCTACCTGCAACGCTTCAA
TGACGCCGTCGTCGTGGTGAAATTCGGTGGCAACGCCATGGGCGACGACGCCGAAATGGCGTCCTTTGCCCGGGACATGG
TCCTCTTGCGTCAGGTTGGCGTGAACCCCGTCGTGGTCCATGGCGGCGGCCCGATGATCAACGACATGCTGGCCAAGCTC
GGCATTGAAAGCACGTTTCTGAACGGCAAGCGCGTCACCGACGCCGCGACGGTGGACGTTGTGGAAATGGTCCTGTCGGG
CCGCGTGAACAAGCGCATCGTCCAGGCCATCAACGCCCAGGGCGGCAAGGCCGTCGGCCTCTCGGGCAAAGACGCCAACC
TGATCACCTGCGTGCCTGCCGATCCGGAACTCGGCTTTGTCGGCGACCCGTCCCAGGTCGATCCCAGTGTGATCAATACC
CTCTTTGAGGATGACATCATTCCCGTCATCGCCCCGCTGGGTCAGGGCGCGGAGGGTGAGACCTACAATATCAACGGCGA
TACGGCAGCGGGGGCCATCGCAAGCGCCCTGCAGGCCGACCGCCTGCTGCTGCTGACCAATGTGTCCGGCGTGAAGAATG
CCGCCGGTGACGTCGTGACGGAACTGACCGCCGCCGATGTCGACGCCATGGTCGCCGATGGCACCATCGCGGGCGGCATG
ATCCCCAAGACCGAAACGGCGCTGCAAGCCGTCCGCACGGGCGTGCGCGCCTGCATTATTGTCGATGGCCGCGTCCCCAA
CGCCGTGCTGCTGGAACTCTTTACCGAGCACGGGGCCGGCTCGATGATCAGGGCGTAA

Upstream 100 bases:

>100_bases
GCGCCCCTGCGCGCCTTTGGCGCAATAAAAGACTCAGCACCTTCACACTGACGCGCACGACCCGTAACGTCTCCCTACCT
CTTCAGTCGATCCAGGCGCC

Downstream 100 bases:

>100_bases
CAGATGGATTACGAGACGATTGACGCCACCGCCGCGCGCCGTCACCTCGGCATCGTCGGTGCCTTCCACCCCGGGCCGGA
AGACAACGCCCCGGACGGCA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKTQMTRDNLATARTLSEALPYLQRFNDAVVVVKFGGNAMGDDAEMASFARDMVLLRQVGVNPVVVHGGGPMINDMLAKL
GIESTFLNGKRVTDAATVDVVEMVLSGRVNKRIVQAINAQGGKAVGLSGKDANLITCVPADPELGFVGDPSQVDPSVINT
LFEDDIIPVIAPLGQGAEGETYNINGDTAAGAIASALQADRLLLLTNVSGVKNAAGDVVTELTAADVDAMVADGTIAGGM
IPKTETALQAVRTGVRACIIVDGRVPNAVLLELFTEHGAGSMIRA

Sequences:

>Translated_285_residues
MKTQMTRDNLATARTLSEALPYLQRFNDAVVVVKFGGNAMGDDAEMASFARDMVLLRQVGVNPVVVHGGGPMINDMLAKL
GIESTFLNGKRVTDAATVDVVEMVLSGRVNKRIVQAINAQGGKAVGLSGKDANLITCVPADPELGFVGDPSQVDPSVINT
LFEDDIIPVIAPLGQGAEGETYNINGDTAAGAIASALQADRLLLLTNVSGVKNAAGDVVTELTAADVDAMVADGTIAGGM
IPKTETALQAVRTGVRACIIVDGRVPNAVLLELFTEHGAGSMIRA
>Mature_285_residues
MKTQMTRDNLATARTLSEALPYLQRFNDAVVVVKFGGNAMGDDAEMASFARDMVLLRQVGVNPVVVHGGGPMINDMLAKL
GIESTFLNGKRVTDAATVDVVEMVLSGRVNKRIVQAINAQGGKAVGLSGKDANLITCVPADPELGFVGDPSQVDPSVINT
LFEDDIIPVIAPLGQGAEGETYNINGDTAAGAIASALQADRLLLLTNVSGVKNAAGDVVTELTAADVDAMVADGTIAGGM
IPKTETALQAVRTGVRACIIVDGRVPNAVLLELFTEHGAGSMIRA

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=235, Percent_Identity=34.0425531914894, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789181, Length=279, Percent_Identity=26.5232974910394, Blast_Score=101, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320913, Length=281, Percent_Identity=25.9786476868327, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_JANSC (Q28UR2)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508575.1
- ProteinModelPortal:   Q28UR2
- SMR:   Q28UR2
- STRING:   Q28UR2
- GeneID:   3933075
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0633
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q28UR2
- ProtClustDB:   PRK00942
- BioCyc:   JSP290400:JANN_0633-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 29525; Mature: 29525

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: BINDING 91-91 BINDING 183-183

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQMTRDNLATARTLSEALPYLQRFNDAVVVVKFGGNAMGDDAEMASFARDMVLLRQVG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
VNPVVVHGGGPMINDMLAKLGIESTFLNGKRVTDAATVDVVEMVLSGRVNKRIVQAINAQ
CCEEEEECCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
GGKAVGLSGKDANLITCVPADPELGFVGDPSQVDPSVINTLFEDDIIPVIAPLGQGAEGE
CCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCC
TYNINGDTAAGAIASALQADRLLLLTNVSGVKNAAGDVVTELTAADVDAMVADGTIAGGM
EEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCEECCCC
IPKTETALQAVRTGVRACIIVDGRVPNAVLLELFTEHGAGSMIRA
CCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKTQMTRDNLATARTLSEALPYLQRFNDAVVVVKFGGNAMGDDAEMASFARDMVLLRQVG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
VNPVVVHGGGPMINDMLAKLGIESTFLNGKRVTDAATVDVVEMVLSGRVNKRIVQAINAQ
CCEEEEECCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
GGKAVGLSGKDANLITCVPADPELGFVGDPSQVDPSVINTLFEDDIIPVIAPLGQGAEGE
CCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCC
TYNINGDTAAGAIASALQADRLLLLTNVSGVKNAAGDVVTELTAADVDAMVADGTIAGGM
EEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCEECCCC
IPKTETALQAVRTGVRACIIVDGRVPNAVLLELFTEHGAGSMIRA
CCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA