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The map label for this gene is accA

Identifier: 89052964

GI number: 89052964

Start: 471113

End: 472072

Strand: Direct

Name: accA

Synonym: Jann_0473

Alternate gene names: 89052964

Gene position: 471113-472072 (Clockwise)

Preceding gene: 89052963

Following gene: 89052965

Centisome position: 10.91

GC content: 61.77

Gene sequence:

>960_bases
ATGAACTATCTCGACTTCGAAAAGCCCCTCGCCGAGATTGAAGGCAAGGCTGAAGAGTTGCGTGCCATGGCGCGTCGCGA
AGAAGGGATGGACGTCGAAGAACAGGCCGCAGCGCTTGATAAAAAGGCCGCAGATCTGCTGCGGACGCTCTACGCCGATC
TGACCCCCTGGCGGAAATGTCAGGTCGCCCGCCACGCGCAGCGGCCCCATTGTCAAGACTACATCGACGCTCTGTTCACC
GAGTATACGCCCTTGGCTGGTGACCGGAACTTCGCCGATGACCATGCGATTATGGGCGGTCTGGCGCGCTTTGACGACAC
CCCCGTCGTCGTGATCGGCCACGAGAAAGGGCACGACACCAAGACCCGCATCGAACGCAATTTCGGCATGGCGCGCCCCG
AGGGATACCGAAAGGCAGTGCGTCTGATGGACCTGGCAGACCGGTTCAATCTGCCCGTCATAACGTTGGTCGACACCCCC
GGCGCTTACCCCGGCAAAGGCGCAGAGGAGCGCGGCCAGTCGGAGGCAATCGCACGATCCACAGAAAAATGTCTGCAAAT
CGGTGTGCCCCTTATCTCGGTCATCATTGGTGAGGGCGGCTCGGGCGGGGCGGTGGCGTTTGCAACGGCGGATCGGCTCG
CGATGCTGGAGCATTCCGTTTACTCCGTGATTAGCCCGGAAGGCTGCGCTTCCATCCTGTGGAAAGACGCGGAAAAGATG
CGCGAAGCGGCTGAGGCGCTGCGCCTGACCGCTCAGGACCTGCACAAGCTGGGAGTGTGCGACGTTGTAATCAACGAACC
CCTTGGTGGGGCGCAGCGCAACAAGGACGCGGCGATTGAAAGCGTCGGCAAGGCGATTGCCTCCATGCTGGCGGGCTTTG
GTGACGCAGACCGCGCGACCTTGATCGCGGGGCGGCGCAAGAAGTTCCTGGATCTGGGCTCCAAGGGTCTTGCGGCTTGA

Upstream 100 bases:

>100_bases
ACCGCAGCCATAGCTGACAGAGCGTGATCTGCTGAGTTGCATCCCTCCCCCCACGCCGCCATATATCGGAGGTCCGGCCA
TGATGTGAGAGCGACCTGCG

Downstream 100 bases:

>100_bases
CCAATCGCAGGCAAGCCCTGTGTGGCCTCCTTGCCGGGCCGCTTCTGGCCCTTCCGTTGAAAGCAGAGCCCATGCGCCCG
ATTGCCGATTTCTCCTGGCG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNYLDFEKPLAEIEGKAEELRAMARREEGMDVEEQAAALDKKAADLLRTLYADLTPWRKCQVARHAQRPHCQDYIDALFT
EYTPLAGDRNFADDHAIMGGLARFDDTPVVVIGHEKGHDTKTRIERNFGMARPEGYRKAVRLMDLADRFNLPVITLVDTP
GAYPGKGAEERGQSEAIARSTEKCLQIGVPLISVIIGEGGSGGAVAFATADRLAMLEHSVYSVISPEGCASILWKDAEKM
REAAEALRLTAQDLHKLGVCDVVINEPLGGAQRNKDAAIESVGKAIASMLAGFGDADRATLIAGRRKKFLDLGSKGLAA

Sequences:

>Translated_319_residues
MNYLDFEKPLAEIEGKAEELRAMARREEGMDVEEQAAALDKKAADLLRTLYADLTPWRKCQVARHAQRPHCQDYIDALFT
EYTPLAGDRNFADDHAIMGGLARFDDTPVVVIGHEKGHDTKTRIERNFGMARPEGYRKAVRLMDLADRFNLPVITLVDTP
GAYPGKGAEERGQSEAIARSTEKCLQIGVPLISVIIGEGGSGGAVAFATADRLAMLEHSVYSVISPEGCASILWKDAEKM
REAAEALRLTAQDLHKLGVCDVVINEPLGGAQRNKDAAIESVGKAIASMLAGFGDADRATLIAGRRKKFLDLGSKGLAA
>Mature_319_residues
MNYLDFEKPLAEIEGKAEELRAMARREEGMDVEEQAAALDKKAADLLRTLYADLTPWRKCQVARHAQRPHCQDYIDALFT
EYTPLAGDRNFADDHAIMGGLARFDDTPVVVIGHEKGHDTKTRIERNFGMARPEGYRKAVRLMDLADRFNLPVITLVDTP
GAYPGKGAEERGQSEAIARSTEKCLQIGVPLISVIIGEGGSGGAVAFATADRLAMLEHSVYSVISPEGCASILWKDAEKM
REAAEALRLTAQDLHKLGVCDVVINEPLGGAQRNKDAAIESVGKAIASMLAGFGDADRATLIAGRRKKFLDLGSKGLAA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=320, Percent_Identity=51.25, Blast_Score=336, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_JANSC (Q28V72)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508415.1
- ProteinModelPortal:   Q28V72
- SMR:   Q28V72
- STRING:   Q28V72
- GeneID:   3932914
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0473
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   DRIIPER
- PhylomeDB:   Q28V72
- ProtClustDB:   PRK05724
- BioCyc:   JSP290400:JANN_0473-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34635; Mature: 34635

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLDFEKPLAEIEGKAEELRAMARREEGMDVEEQAAALDKKAADLLRTLYADLTPWRKC
CCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QVARHAQRPHCQDYIDALFTEYTPLAGDRNFADDHAIMGGLARFDDTPVVVIGHEKGHDT
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCH
KTRIERNFGMARPEGYRKAVRLMDLADRFNLPVITLVDTPGAYPGKGAEERGQSEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCHHHHHHHH
TEKCLQIGVPLISVIIGEGGSGGAVAFATADRLAMLEHSVYSVISPEGCASILWKDAEKM
HHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
REAAEALRLTAQDLHKLGVCDVVINEPLGGAQRNKDAAIESVGKAIASMLAGFGDADRAT
HHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
LIAGRRKKFLDLGSKGLAA
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNYLDFEKPLAEIEGKAEELRAMARREEGMDVEEQAAALDKKAADLLRTLYADLTPWRKC
CCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QVARHAQRPHCQDYIDALFTEYTPLAGDRNFADDHAIMGGLARFDDTPVVVIGHEKGHDT
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCH
KTRIERNFGMARPEGYRKAVRLMDLADRFNLPVITLVDTPGAYPGKGAEERGQSEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCHHHHHHHH
TEKCLQIGVPLISVIIGEGGSGGAVAFATADRLAMLEHSVYSVISPEGCASILWKDAEKM
HHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
REAAEALRLTAQDLHKLGVCDVVINEPLGGAQRNKDAAIESVGKAIASMLAGFGDADRAT
HHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
LIAGRRKKFLDLGSKGLAA
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA