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The map label for this gene is recQ [H]

Identifier: 89052934

GI number: 89052934

Start: 446342

End: 448399

Strand: Direct

Name: recQ [H]

Synonym: Jann_0443

Alternate gene names: 89052934

Gene position: 446342-448399 (Clockwise)

Preceding gene: 89052933

Following gene: 89052935

Centisome position: 10.34

GC content: 63.02

Gene sequence:

>2058_bases
ATGTTGGTCGAACACCCCGACACATCTGCGATTTTGAAATCCACCTTCGGATTTGACGCCTTCCGCCCCGGTCAGGCGGA
AATTGTGGAGGCTGTGGCGTCCGGCAAAGACGTCTTGGCCATTATGCCAACCGGCGGCGGCAAAAGCCTTTGTTTCCAGC
TGCCCGCACTGGTTCGCGACGGAGTTACGGTTGTGATTTCTCCGCTGATTGCGCTGATGCGCGATCAGGTGCGCGGTCTG
CGGGAAGCGGGGGTGGAGGCGGGCGCTTTGACCTCTGGCAATACGCCCGAGGAAACGGACGCGGTGTGGGAGGGACTGGA
GCGCGGGACGCTGAAGTTGCTCTACCTCGCGCCGGAACGGCTTGCCTCAACGGGGACGGAACGGATGTTGGCACGCGCGG
GCGTATCGATGATCGCCGTGGATGAAGCCCATTGTGTCAGCCAGTGGGGCCACGATTTCCGTCCCGATTATCTGCGCCTT
GGCGCGTTGCGTCGTGCGCTGAACGTCCCGCTGGCCGCTTTCACCGCCACGGCGGACGCAGAAACGCGGGCCGAGATTTG
CGAACGCCTGTTCGAGGACCCGCCAGAGGTGTTCCTGCATGGCTTCGACCGCCCAAACCTGACCCTCGCGTTTGAGGTCA
AGAACCAGCCGCGCCAGCAGATCCTGTCGTTTGCCGCCGCGCGCAAAGGCCAGTCCGGCATCGTCTATTGCGGCACACGG
GCGAAGACGGAAACGCTTGCCAAGGCTTTGCGGGACGAGGGCCACAGCGCCTGCCATTACCATGGTGGGATGGAGGCGGA
TGACCGACGGATTGTGGAGACCCGCTTTAACCGCGAAGACGGCTTGATCGTCTGCGCTACGGTGGCTTTTGGGATGGGGG
TCGACAAGCCCGATATCCGTTGGGTCGCCCATGCCGATCTGCCCAAGTCGATCGAGGGGTATTATCAGGAAATCGGTCGT
GCCGGTCGCGACGGCGCGCCTGCCGATACGCTGACGCTCTACGGTCCCGATGATATCCGCTTCCGGCGCCAGCAGGTGGA
CGAGGGCCTCGCCCCGCCAGAACGCAAAACAGCAGACCACGCCCGCCTGAACGCGCTTCTGGGTCTGGCGGAAGCGCAGG
GATGTCGCCGTAAAGTGCTGCTGTCCTACTTCGGGGATGAGGCTGAGGATTGTGGCAATTGTGATCTCTGCGCCAGGCCG
CCGGAATTATTTGACGCCTCCGTTGCCGTGCAAAAGGCGCTGTCCGTGATGCTGCGCACAGGTGAATATTTCGGCGCGGG
TCATTTGATAGATGTCCTCCTTGGCGCGCAGAATGAGAAGATCAGGCAGCGGGGTCATGATCGTCTGTCGACCTACGGCA
TCGGGACGGAGTTCGACAAACGCGGCTGGCAGGCCGTGTTCCGGCAGATGATGGGACGCGACCTTGTCCGCCCCGATCCG
GAGCGTCACGGCGCGTTTCGCATGACCGACGCTGCGCGCCCTATTTTGCGCGGGGAAGAAGGCATCACGCTGCGCAAAGA
TACGATCTCAAAAGCGCCCCGCCGTCCCGCCGTGAAGATGCTGGTGAGCGAGGAGGACGCGCCGCTGATGTCCGCACTGA
AAGCCAAGCGCCGCGCCTTGGCCGAGGATGCGCGCGTGCCCGCTTACGTGATTTTCACCGACAAGACGTTGATCGAAATG
GCCGAGAAACGACCGGACACCCTGGACGACATGGCCCGCATTTCCGGTGTTGGGGCCACCAAGCTGGAACGGTATGGCAC
GGCATTCCTGCAAGTCATAACGGGTGACACGCCTGAGGCCGTTCACCCCGCCCGCCGTGCACTGGCCGGGCGCGATGCAG
GCGATGTCTTCGACAGGCTGATGGAGGTCCAGCAGGACCTGATGCGCGGGGACGACGGCACGGGCAAGTATCTCTCGGTC
AATCACTCGACGCTTCGCAGGATCGCCGAGCGCAGGCCCGCCTCGCTGCACGATATGGCGCGGATCGCGGGTATGGGCGA
CAAGCAGGTGGACCGCTTTGCGGAAGCGTTTCTGGAGGTTCTGCGCGAGGCTGGATAA

Upstream 100 bases:

>100_bases
ACAAGATGTTGGCGTCCCGGGTCTTGTTTACGGAATCTCAATATGGGACCATCTAGATAACAACGAGCATTTAGATAAAA
ATCAACAGGCTGCCCCAACG

Downstream 100 bases:

>100_bases
ACCGCCCGACGCGCTTACATCTATACACAGACGTTAGAGGAGGCTTTGCATATGCTCACCGTGATTTCCCCCGCCAAACG
CCTGGATTGGGCGAAGCGTG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MLVEHPDTSAILKSTFGFDAFRPGQAEIVEAVASGKDVLAIMPTGGGKSLCFQLPALVRDGVTVVISPLIALMRDQVRGL
REAGVEAGALTSGNTPEETDAVWEGLERGTLKLLYLAPERLASTGTERMLARAGVSMIAVDEAHCVSQWGHDFRPDYLRL
GALRRALNVPLAAFTATADAETRAEICERLFEDPPEVFLHGFDRPNLTLAFEVKNQPRQQILSFAAARKGQSGIVYCGTR
AKTETLAKALRDEGHSACHYHGGMEADDRRIVETRFNREDGLIVCATVAFGMGVDKPDIRWVAHADLPKSIEGYYQEIGR
AGRDGAPADTLTLYGPDDIRFRRQQVDEGLAPPERKTADHARLNALLGLAEAQGCRRKVLLSYFGDEAEDCGNCDLCARP
PELFDASVAVQKALSVMLRTGEYFGAGHLIDVLLGAQNEKIRQRGHDRLSTYGIGTEFDKRGWQAVFRQMMGRDLVRPDP
ERHGAFRMTDAARPILRGEEGITLRKDTISKAPRRPAVKMLVSEEDAPLMSALKAKRRALAEDARVPAYVIFTDKTLIEM
AEKRPDTLDDMARISGVGATKLERYGTAFLQVITGDTPEAVHPARRALAGRDAGDVFDRLMEVQQDLMRGDDGTGKYLSV
NHSTLRRIAERRPASLHDMARIAGMGDKQVDRFAEAFLEVLREAG

Sequences:

>Translated_685_residues
MLVEHPDTSAILKSTFGFDAFRPGQAEIVEAVASGKDVLAIMPTGGGKSLCFQLPALVRDGVTVVISPLIALMRDQVRGL
REAGVEAGALTSGNTPEETDAVWEGLERGTLKLLYLAPERLASTGTERMLARAGVSMIAVDEAHCVSQWGHDFRPDYLRL
GALRRALNVPLAAFTATADAETRAEICERLFEDPPEVFLHGFDRPNLTLAFEVKNQPRQQILSFAAARKGQSGIVYCGTR
AKTETLAKALRDEGHSACHYHGGMEADDRRIVETRFNREDGLIVCATVAFGMGVDKPDIRWVAHADLPKSIEGYYQEIGR
AGRDGAPADTLTLYGPDDIRFRRQQVDEGLAPPERKTADHARLNALLGLAEAQGCRRKVLLSYFGDEAEDCGNCDLCARP
PELFDASVAVQKALSVMLRTGEYFGAGHLIDVLLGAQNEKIRQRGHDRLSTYGIGTEFDKRGWQAVFRQMMGRDLVRPDP
ERHGAFRMTDAARPILRGEEGITLRKDTISKAPRRPAVKMLVSEEDAPLMSALKAKRRALAEDARVPAYVIFTDKTLIEM
AEKRPDTLDDMARISGVGATKLERYGTAFLQVITGDTPEAVHPARRALAGRDAGDVFDRLMEVQQDLMRGDDGTGKYLSV
NHSTLRRIAERRPASLHDMARIAGMGDKQVDRFAEAFLEVLREAG
>Mature_685_residues
MLVEHPDTSAILKSTFGFDAFRPGQAEIVEAVASGKDVLAIMPTGGGKSLCFQLPALVRDGVTVVISPLIALMRDQVRGL
REAGVEAGALTSGNTPEETDAVWEGLERGTLKLLYLAPERLASTGTERMLARAGVSMIAVDEAHCVSQWGHDFRPDYLRL
GALRRALNVPLAAFTATADAETRAEICERLFEDPPEVFLHGFDRPNLTLAFEVKNQPRQQILSFAAARKGQSGIVYCGTR
AKTETLAKALRDEGHSACHYHGGMEADDRRIVETRFNREDGLIVCATVAFGMGVDKPDIRWVAHADLPKSIEGYYQEIGR
AGRDGAPADTLTLYGPDDIRFRRQQVDEGLAPPERKTADHARLNALLGLAEAQGCRRKVLLSYFGDEAEDCGNCDLCARP
PELFDASVAVQKALSVMLRTGEYFGAGHLIDVLLGAQNEKIRQRGHDRLSTYGIGTEFDKRGWQAVFRQMMGRDLVRPDP
ERHGAFRMTDAARPILRGEEGITLRKDTISKAPRRPAVKMLVSEEDAPLMSALKAKRRALAEDARVPAYVIFTDKTLIEM
AEKRPDTLDDMARISGVGATKLERYGTAFLQVITGDTPEAVHPARRALAGRDAGDVFDRLMEVQQDLMRGDDGTGKYLSV
NHSTLRRIAERRPASLHDMARIAGMGDKQVDRFAEAFLEVLREAG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=634, Percent_Identity=32.4921135646688, Blast_Score=310, Evalue=4e-84,
Organism=Homo sapiens, GI14591902, Length=409, Percent_Identity=38.3863080684597, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI14591904, Length=409, Percent_Identity=38.3863080684597, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI148612816, Length=443, Percent_Identity=39.7291196388262, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI110735439, Length=707, Percent_Identity=29.5615275813296, Blast_Score=275, Evalue=7e-74,
Organism=Homo sapiens, GI169218196, Length=707, Percent_Identity=29.5615275813296, Blast_Score=275, Evalue=8e-74,
Organism=Homo sapiens, GI51242947, Length=350, Percent_Identity=43.1428571428571, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI51242943, Length=350, Percent_Identity=43.1428571428571, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI284005309, Length=358, Percent_Identity=37.7094972067039, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI222352149, Length=362, Percent_Identity=22.0994475138122, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI148613856, Length=372, Percent_Identity=23.3870967741935, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38201710, Length=372, Percent_Identity=23.3870967741935, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=587, Percent_Identity=45.8262350936968, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI87082221, Length=333, Percent_Identity=26.7267267267267, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787016, Length=345, Percent_Identity=25.2173913043478, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787605, Length=337, Percent_Identity=24.3323442136499, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=642, Percent_Identity=31.619937694704, Blast_Score=291, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI71987993, Length=409, Percent_Identity=38.6308068459658, Blast_Score=274, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71987997, Length=409, Percent_Identity=38.6308068459658, Blast_Score=274, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI32564293, Length=486, Percent_Identity=34.156378600823, Blast_Score=272, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17552866, Length=407, Percent_Identity=38.5749385749386, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI115533224, Length=330, Percent_Identity=25.7575757575758, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323844, Length=553, Percent_Identity=34.5388788426763, Blast_Score=322, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6320224, Length=326, Percent_Identity=22.3926380368098, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320041, Length=352, Percent_Identity=23.8636363636364, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324217, Length=340, Percent_Identity=23.8235294117647, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320119, Length=330, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321360, Length=350, Percent_Identity=24, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646066, Length=641, Percent_Identity=32.2932917316693, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24664226, Length=444, Percent_Identity=37.6126126126126, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24664230, Length=444, Percent_Identity=37.6126126126126, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI62472181, Length=444, Percent_Identity=37.6126126126126, Blast_Score=256, Evalue=5e-68,
Organism=Drosophila melanogaster, GI21358123, Length=366, Percent_Identity=36.0655737704918, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24642151, Length=358, Percent_Identity=24.5810055865922, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574962, Length=335, Percent_Identity=22.6865671641791, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355075, Length=379, Percent_Identity=22.9551451187335, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75289; Mature: 75289

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVEHPDTSAILKSTFGFDAFRPGQAEIVEAVASGKDVLAIMPTGGGKSLCFQLPALVRD
CCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHC
GVTVVISPLIALMRDQVRGLREAGVEAGALTSGNTPEETDAVWEGLERGTLKLLYLAPER
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECHHH
LASTGTERMLARAGVSMIAVDEAHCVSQWGHDFRPDYLRLGALRRALNVPLAAFTATADA
HHHCCHHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCH
ETRAEICERLFEDPPEVFLHGFDRPNLTLAFEVKNQPRQQILSFAAARKGQSGIVYCGTR
HHHHHHHHHHHCCCHHHHEECCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCC
AKTETLAKALRDEGHSACHYHGGMEADDRRIVETRFNREDGLIVCATVAFGMGVDKPDIR
HHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCE
WVAHADLPKSIEGYYQEIGRAGRDGAPADTLTLYGPDDIRFRRQQVDEGLAPPERKTADH
EEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHH
ARLNALLGLAEAQGCRRKVLLSYFGDEAEDCGNCDLCARPPELFDASVAVQKALSVMLRT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GEYFGAGHLIDVLLGAQNEKIRQRGHDRLSTYGIGTEFDKRGWQAVFRQMMGRDLVRPDP
CCCCCCHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
ERHGAFRMTDAARPILRGEEGITLRKDTISKAPRRPAVKMLVSEEDAPLMSALKAKRRAL
CCCCCEEECHHHCHHHCCCCCCEEEHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHH
AEDARVPAYVIFTDKTLIEMAEKRPDTLDDMARISGVGATKLERYGTAFLQVITGDTPEA
HHHCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCHH
VHPARRALAGRDAGDVFDRLMEVQQDLMRGDDGTGKYLSVNHSTLRRIAERRPASLHDMA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHH
RIAGMGDKQVDRFAEAFLEVLREAG
HHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVEHPDTSAILKSTFGFDAFRPGQAEIVEAVASGKDVLAIMPTGGGKSLCFQLPALVRD
CCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHC
GVTVVISPLIALMRDQVRGLREAGVEAGALTSGNTPEETDAVWEGLERGTLKLLYLAPER
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECHHH
LASTGTERMLARAGVSMIAVDEAHCVSQWGHDFRPDYLRLGALRRALNVPLAAFTATADA
HHHCCHHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCH
ETRAEICERLFEDPPEVFLHGFDRPNLTLAFEVKNQPRQQILSFAAARKGQSGIVYCGTR
HHHHHHHHHHHCCCHHHHEECCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCC
AKTETLAKALRDEGHSACHYHGGMEADDRRIVETRFNREDGLIVCATVAFGMGVDKPDIR
HHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCE
WVAHADLPKSIEGYYQEIGRAGRDGAPADTLTLYGPDDIRFRRQQVDEGLAPPERKTADH
EEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHH
ARLNALLGLAEAQGCRRKVLLSYFGDEAEDCGNCDLCARPPELFDASVAVQKALSVMLRT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GEYFGAGHLIDVLLGAQNEKIRQRGHDRLSTYGIGTEFDKRGWQAVFRQMMGRDLVRPDP
CCCCCCHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
ERHGAFRMTDAARPILRGEEGITLRKDTISKAPRRPAVKMLVSEEDAPLMSALKAKRRAL
CCCCCEEECHHHCHHHCCCCCCEEEHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHH
AEDARVPAYVIFTDKTLIEMAEKRPDTLDDMARISGVGATKLERYGTAFLQVITGDTPEA
HHHCCCCEEEEECCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHEECCCCCHH
VHPARRALAGRDAGDVFDRLMEVQQDLMRGDDGTGKYLSVNHSTLRRIAERRPASLHDMA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHH
RIAGMGDKQVDRFAEAFLEVLREAG
HHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]