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The map label for this gene is rlmH

Identifier: 89052869

GI number: 89052869

Start: 383715

End: 384128

Strand: Direct

Name: rlmH

Synonym: Jann_0378

Alternate gene names: 89052869

Gene position: 383715-384128 (Clockwise)

Preceding gene: 89052868

Following gene: 89052870

Centisome position: 8.89

GC content: 64.01

Gene sequence:

>414_bases
TTGATCGACGATTATTTAAGACGTTTCGACAAGACGGGCCGGGGCCTGGGCCTATCCCTTGGGCAGGTCGTGGAGGTCGA
AAACCGCAAAGGCGGCGGCATGGCGGCGGAGGCGGATTTGATTCGCGCGCGCCTGCCCGGTGGTGTCTTTTGGGTGATGG
ATGAACGCGGCGATGTGATGACGTCGCCCGGGTTCGCGGATCGCTTAGGCGCGCAGAGAGACCGGGGCGCGGGCGATCTG
ACGATGGTTATCGGCGGGGCGGACGGAATTGACCCCACGCTGAGGGACGAGGCGGGGATGGCGATTTCCTTCGGCAAGAT
GGTCTGGCCGCATATGCTGGCGCGGGTCATGCTGAGTGAGCAATTGTACCGGGCCGCGTCTATTCTGGCGGGCGGCCCGT
ATCACCGGGTCTAG

Upstream 100 bases:

>100_bases
AGCCAGAGGCGCCTGAGACGACCCCGGGCCCCGGGGCCGCGGCGCCCTGAACGTCCACCTATGCGTCGCGGGCCGTCTGA
AGGCAGGCCCCGAGAAGACG

Downstream 100 bases:

>100_bases
GACAGACCGGATTTTGCCGATCCTGGCCACATCAGGATCCGCGGCCTGTGACGCCTGAGCCGCTGCACGCCTGATGTAAG
CGGCCCCACGGCCCGGAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MIDDYLRRFDKTGRGLGLSLGQVVEVENRKGGGMAAEADLIRARLPGGVFWVMDERGDVMTSPGFADRLGAQRDRGAGDL
TMVIGGADGIDPTLRDEAGMAISFGKMVWPHMLARVMLSEQLYRAASILAGGPYHRV

Sequences:

>Translated_137_residues
MIDDYLRRFDKTGRGLGLSLGQVVEVENRKGGGMAAEADLIRARLPGGVFWVMDERGDVMTSPGFADRLGAQRDRGAGDL
TMVIGGADGIDPTLRDEAGMAISFGKMVWPHMLARVMLSEQLYRAASILAGGPYHRV
>Mature_137_residues
MIDDYLRRFDKTGRGLGLSLGQVVEVENRKGGGMAAEADLIRARLPGGVFWVMDERGDVMTSPGFADRLGAQRDRGAGDL
TMVIGGADGIDPTLRDEAGMAISFGKMVWPHMLARVMLSEQLYRAASILAGGPYHRV

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_JANSC (Q28VG7)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508320.1
- ProteinModelPortal:   Q28VG7
- SMR:   Q28VG7
- STRING:   Q28VG7
- GeneID:   3932819
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0378
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   DEAGMAI
- PhylomeDB:   Q28VG7
- BioCyc:   JSP290400:JANN_0378-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 14809; Mature: 14809

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDYLRRFDKTGRGLGLSLGQVVEVENRKGGGMAAEADLIRARLPGGVFWVMDERGDVM
CCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEE
TSPGFADRLGAQRDRGAGDLTMVIGGADGIDPTLRDEAGMAISFGKMVWPHMLARVMLSE
ECCCCHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
QLYRAASILAGGPYHRV
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIDDYLRRFDKTGRGLGLSLGQVVEVENRKGGGMAAEADLIRARLPGGVFWVMDERGDVM
CCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEE
TSPGFADRLGAQRDRGAGDLTMVIGGADGIDPTLRDEAGMAISFGKMVWPHMLARVMLSE
ECCCCHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
QLYRAASILAGGPYHRV
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA