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The map label for this gene is yleA [C]

Identifier: 89052810

GI number: 89052810

Start: 326486

End: 327745

Strand: Direct

Name: yleA [C]

Synonym: Jann_0319

Alternate gene names: 89052810

Gene position: 326486-327745 (Clockwise)

Preceding gene: 89052809

Following gene: 89052811

Centisome position: 7.56

GC content: 60.56

Gene sequence:

>1260_bases
ATGAGCGCGCCAGTGTTCCACACGCTTGGCTGCCGTCTCAACGCCTATGAGACCGAGGCAATGCGTGAGATGACGGCTCA
GGCGGGCCTCGAAAACGCCGTCGTGGTGAACACCTGCGCGGTGACGGCGGAAGCGGTTCGCAAGGCCCGGCAGGAAATTC
GCAAGCTGCGGCGGGACAGTCCCGGCGCGAAGGTCATCGTCACCGGCTGCGCCGCCCAGACCGAGCCTGCGACGTTCGAG
GCGATGGAAGAGGTGGACCTCGTCCTCGGCAATTCCGAGAAGATGACCCCGGAGACGTGGCAGGCGATGCCCGCAGACTT
TATCGGCAACACCGAGAAGGTTCGCGTCGATGACATCATGTCAGTGACGGAGACGGCGCAGCATCTGATCGACGGCTTCG
GGACGCGGTCCCGCGCTTATGTTCAGGTGCAAAATGGCTGCGATCATCGCTGCACGTTCTGCATTATTCCATATGGGCGC
GGGAATTCTCGGTCAGTCCCAGCGGGCGTTGTTGTGGATCAGATCAAGCGGTTGGTGGATCGTGGGTATAATGAAGTCGT
GCTGACCGGCGTCGATATGACGTCCTGGGGCGCGGACCTGCCTGCTGCGCCCAGACTTGGCGATCTGGTCATGCGCATCC
TCAAACTTGTGCCGGACCTGCCCCGCCTGCGGATCAGTTCCATCGACTCGATCGAAGTGGACGACGCGCTGATGCAGGCC
ATCGCGACGGAGCCGCGTCTGATGCCGCATCTCCACCTCAGCCTGCAACATGGCGACGACCTGATCCTCAAGCGGATGAA
GCGGCGACATCTTCGGGATGACGCGATTGCATTTTGCGAAGAGGCGCGTCGCCTACGGCCCGAGATCACGTTCGGGGCTG
ATATCATCGCTGGCTTCCCGACCGAGACGGAGGCGCATTTCCAGAACTCCGTGAAGCTGGTGGAGGAGTGTGATCTGACG
TGGCTGCACGTCTTCCCCTATAGTCCACGTGAAGGGACCCCTGCGGCCAGAATGCCGGCTGTTGATGGTCCAACGATCAA
GGCGCGCGCAAAGCAGCTTCGGGCCAAAGGTGAGGCTGCCGTTAACGCGCACCTGTCCAAACAGATAGGGCAATTGCACA
ACATCCTGATGGAAAGCCCTAAAATTGGGCGGACTGAACAGTTCACGGAGGTTGTCTTCGCCGAGGATCAACCCGAAGGA
GAGATTGTAAGCGCATACATAACTGGGCAGACGGATCGACAGCTACTGGTCGCGTCCTGA

Upstream 100 bases:

>100_bases
GCGAGATCAGCGTGGATTGGCGCAGCGATGGCGTCTGGATGACAGGCCCCACCGCCCACGTCTTTTCCGGGGAACTGACC
CCGGCCTTCCTGGACGCACT

Downstream 100 bases:

>100_bases
ACCCCTCTGTCTTGAGGTCGTCCCATGCACCCGAACCCGGCGTTCCGCCAAGAGCCCGTCTTTACCAACGTTGCCATGTG
CCAGAAGCGTGGCTTCGGGA

Product: MiaB-like tRNA modifying protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSAPVFHTLGCRLNAYETEAMREMTAQAGLENAVVVNTCAVTAEAVRKARQEIRKLRRDSPGAKVIVTGCAAQTEPATFE
AMEEVDLVLGNSEKMTPETWQAMPADFIGNTEKVRVDDIMSVTETAQHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGR
GNSRSVPAGVVVDQIKRLVDRGYNEVVLTGVDMTSWGADLPAAPRLGDLVMRILKLVPDLPRLRISSIDSIEVDDALMQA
IATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIAFCEEARRLRPEITFGADIIAGFPTETEAHFQNSVKLVEECDLT
WLHVFPYSPREGTPAARMPAVDGPTIKARAKQLRAKGEAAVNAHLSKQIGQLHNILMESPKIGRTEQFTEVVFAEDQPEG
EIVSAYITGQTDRQLLVAS

Sequences:

>Translated_419_residues
MSAPVFHTLGCRLNAYETEAMREMTAQAGLENAVVVNTCAVTAEAVRKARQEIRKLRRDSPGAKVIVTGCAAQTEPATFE
AMEEVDLVLGNSEKMTPETWQAMPADFIGNTEKVRVDDIMSVTETAQHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGR
GNSRSVPAGVVVDQIKRLVDRGYNEVVLTGVDMTSWGADLPAAPRLGDLVMRILKLVPDLPRLRISSIDSIEVDDALMQA
IATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIAFCEEARRLRPEITFGADIIAGFPTETEAHFQNSVKLVEECDLT
WLHVFPYSPREGTPAARMPAVDGPTIKARAKQLRAKGEAAVNAHLSKQIGQLHNILMESPKIGRTEQFTEVVFAEDQPEG
EIVSAYITGQTDRQLLVAS
>Mature_418_residues
SAPVFHTLGCRLNAYETEAMREMTAQAGLENAVVVNTCAVTAEAVRKARQEIRKLRRDSPGAKVIVTGCAAQTEPATFEA
MEEVDLVLGNSEKMTPETWQAMPADFIGNTEKVRVDDIMSVTETAQHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRG
NSRSVPAGVVVDQIKRLVDRGYNEVVLTGVDMTSWGADLPAAPRLGDLVMRILKLVPDLPRLRISSIDSIEVDDALMQAI
ATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIAFCEEARRLRPEITFGADIIAGFPTETEAHFQNSVKLVEECDLTW
LHVFPYSPREGTPAARMPAVDGPTIKARAKQLRAKGEAAVNAHLSKQIGQLHNILMESPKIGRTEQFTEVVFAEDQPEGE
IVSAYITGQTDRQLLVAS

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=377, Percent_Identity=27.0557029177719, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI28872782, Length=385, Percent_Identity=23.3766233766234, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI28872784, Length=381, Percent_Identity=22.8346456692913, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1786882, Length=428, Percent_Identity=27.5700934579439, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787057, Length=351, Percent_Identity=30.1994301994302, Blast_Score=141, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17553146, Length=385, Percent_Identity=28.5714285714286, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71996771, Length=242, Percent_Identity=30.9917355371901, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21356207, Length=424, Percent_Identity=26.6509433962264, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI19922432, Length=367, Percent_Identity=26.4305177111717, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46319; Mature: 46187

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPVFHTLGCRLNAYETEAMREMTAQAGLENAVVVNTCAVTAEAVRKARQEIRKLRRDS
CCCCCEEHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCC
PGAKVIVTGCAAQTEPATFEAMEEVDLVLGNSEKMTPETWQAMPADFIGNTEKVRVDDIM
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHCCCCCEEEHHHHH
SVTETAQHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRGNSRSVPAGVVVDQIKRLVD
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
RGYNEVVLTGVDMTSWGADLPAAPRLGDLVMRILKLVPDLPRLRISSIDSIEVDDALMQA
CCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
IATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIAFCEEARRLRPEITFGADIIAGFP
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCHHEECCC
TETEAHFQNSVKLVEECDLTWLHVFPYSPREGTPAARMPAVDGPTIKARAKQLRAKGEAA
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHH
VNAHLSKQIGQLHNILMESPKIGRTEQFTEVVFAEDQPEGEIVSAYITGQTDRQLLVAS
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCCCCCCEEEEEEECCCCCEEEEEC
>Mature Secondary Structure 
SAPVFHTLGCRLNAYETEAMREMTAQAGLENAVVVNTCAVTAEAVRKARQEIRKLRRDS
CCCCEEHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCC
PGAKVIVTGCAAQTEPATFEAMEEVDLVLGNSEKMTPETWQAMPADFIGNTEKVRVDDIM
CCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHCCCCCEEEHHHHH
SVTETAQHLIDGFGTRSRAYVQVQNGCDHRCTFCIIPYGRGNSRSVPAGVVVDQIKRLVD
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
RGYNEVVLTGVDMTSWGADLPAAPRLGDLVMRILKLVPDLPRLRISSIDSIEVDDALMQA
CCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
IATEPRLMPHLHLSLQHGDDLILKRMKRRHLRDDAIAFCEEARRLRPEITFGADIIAGFP
HHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCHHEECCC
TETEAHFQNSVKLVEECDLTWLHVFPYSPREGTPAARMPAVDGPTIKARAKQLRAKGEAA
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHH
VNAHLSKQIGQLHNILMESPKIGRTEQFTEVVFAEDQPEGEIVSAYITGQTDRQLLVAS
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCCCCCCEEEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]