Click here to switch to the map view.

The map label for this gene is ubiG

Identifier: 89052789

GI number: 89052789

Start: 304476

End: 305240

Strand: Reverse

Name: ubiG

Synonym: Jann_0298

Alternate gene names: 89052789

Gene position: 305240-304476 (Counterclockwise)

Preceding gene: 89052791

Following gene: 89052785

Centisome position: 7.07

GC content: 61.05

Gene sequence:

>765_bases
ATGACCGCCGCCCCCGATGCAACAGGAACCGTCAACACCGTCGACGCTGGCGAAGTCGCCAAGTTTGAGGCGATGGCCGC
AGAATGGTGGGATCTGGAGGGCAAGTTCAAGCCGCTGCACATGCTCAACCCCACGCGGCTGGACTATATCACACAACAGA
TCGCAGCAGAGTTTGGCCGGGATCTGAAGGCGGACGCGCCGTTTGCGGGCCTGCATATCCTTGATATCGGCTGCGGTGGC
GGGCTTTTGGCGGAGCCGATGGCGCGTCTTGGGGCCGATGTGGTGGGGGCCGACGCGGCGGAGCGGAACATCCCGGTGGC
GCAGGTCCATGCCGCACAATCGGGGCTGGAGATCGACTATCGCCATACGACTGCCGAAGCGATGGCCGACGCCGGAGAGC
AGTTCGACGTTGTTCTGAACATGGAGGTCGTCGAACATGTGGTCGATCCGTTGGGGTATCTGACCGCCTGTCAACGGCTT
CTGAAACCCGGCGGGCTGATGGTGTGTTCGACCCTGAACCGGAACCCGAAAAGCTATCTGATGGCGATCATCGGGGCCGA
GCATGTGATGCGCTGGCTGCCCAAGGGCACGCATGAATGGTCCAAGTTCATCACGCCCGATGAATTATTCGATCTGATCC
GGCAAGCAGGCCTCGACCCCGTGGACCGGAAGGGGTTTGTCTTCAATCCGCTCCTGTGGACCTGGGGTATCAGCGAGCGG
GACATGAGCGTGAATTACGTCACCGCATCGGTGAAACAGGTCTAG

Upstream 100 bases:

>100_bases
TGCGCGCTTTTGGCCCGAGAACTTGTCCATGCCGGTCCTATATAGAGCGTGAGTTGAAAAAACCGCACGAGAAGTGTCGC
AAGAGAGTGAGAGGATGTCC

Downstream 100 bases:

>100_bases
CCTTCATCCTCCAGCTTTCGGCGCACGTCGCGCAGGAGGGGGAGGGTATCGCGAACCCTGCCCGGCCCGATTTCGGCCAC
GGCTTCTGTCAGAATCGGTA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTAAPDATGTVNTVDAGEVAKFEAMAAEWWDLEGKFKPLHMLNPTRLDYITQQIAAEFGRDLKADAPFAGLHILDIGCGG
GLLAEPMARLGADVVGADAAERNIPVAQVHAAQSGLEIDYRHTTAEAMADAGEQFDVVLNMEVVEHVVDPLGYLTACQRL
LKPGGLMVCSTLNRNPKSYLMAIIGAEHVMRWLPKGTHEWSKFITPDELFDLIRQAGLDPVDRKGFVFNPLLWTWGISER
DMSVNYVTASVKQV

Sequences:

>Translated_254_residues
MTAAPDATGTVNTVDAGEVAKFEAMAAEWWDLEGKFKPLHMLNPTRLDYITQQIAAEFGRDLKADAPFAGLHILDIGCGG
GLLAEPMARLGADVVGADAAERNIPVAQVHAAQSGLEIDYRHTTAEAMADAGEQFDVVLNMEVVEHVVDPLGYLTACQRL
LKPGGLMVCSTLNRNPKSYLMAIIGAEHVMRWLPKGTHEWSKFITPDELFDLIRQAGLDPVDRKGFVFNPLLWTWGISER
DMSVNYVTASVKQV
>Mature_253_residues
TAAPDATGTVNTVDAGEVAKFEAMAAEWWDLEGKFKPLHMLNPTRLDYITQQIAAEFGRDLKADAPFAGLHILDIGCGGG
LLAEPMARLGADVVGADAAERNIPVAQVHAAQSGLEIDYRHTTAEAMADAGEQFDVVLNMEVVEHVVDPLGYLTACQRLL
KPGGLMVCSTLNRNPKSYLMAIIGAEHVMRWLPKGTHEWSKFITPDELFDLIRQAGLDPVDRKGFVFNPLLWTWGISERD
MSVNYVTASVKQV

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=245, Percent_Identity=39.1836734693878, Blast_Score=188, Evalue=4e-48,
Organism=Escherichia coli, GI1788564, Length=237, Percent_Identity=46.4135021097046, Blast_Score=214, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI115533050, Length=252, Percent_Identity=34.9206349206349, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6324476, Length=253, Percent_Identity=30.8300395256917, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281365311, Length=260, Percent_Identity=33.8461538461538, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24585589, Length=236, Percent_Identity=34.3220338983051, Blast_Score=131, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_JANSC (Q28VP7)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508240.1
- ProteinModelPortal:   Q28VP7
- SMR:   Q28VP7
- STRING:   Q28VP7
- GeneID:   3932736
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0298
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   KFITPDE
- PhylomeDB:   Q28VP7
- ProtClustDB:   PRK05134
- BioCyc:   JSP290400:JANN_0298-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 27777; Mature: 27646

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAPDATGTVNTVDAGEVAKFEAMAAEWWDLEGKFKPLHMLNPTRLDYITQQIAAEFGR
CCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHCC
DLKADAPFAGLHILDIGCGGGLLAEPMARLGADVVGADAAERNIPVAQVHAAQSGLEIDY
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHCCCHHHCCCCHHHHHHHHCCCEEEE
RHTTAEAMADAGEQFDVVLNMEVVEHVVDPLGYLTACQRLLKPGGLMVCSTLNRNPKSYL
HHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
MAIIGAEHVMRWLPKGTHEWSKFITPDELFDLIRQAGLDPVDRKGFVFNPLLWTWGISER
HHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEECCHHEECCCCCC
DMSVNYVTASVKQV
CCEEEEEECCHHCC
>Mature Secondary Structure 
TAAPDATGTVNTVDAGEVAKFEAMAAEWWDLEGKFKPLHMLNPTRLDYITQQIAAEFGR
CCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHCC
DLKADAPFAGLHILDIGCGGGLLAEPMARLGADVVGADAAERNIPVAQVHAAQSGLEIDY
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHCCCHHHCCCCHHHHHHHHCCCEEEE
RHTTAEAMADAGEQFDVVLNMEVVEHVVDPLGYLTACQRLLKPGGLMVCSTLNRNPKSYL
HHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
MAIIGAEHVMRWLPKGTHEWSKFITPDELFDLIRQAGLDPVDRKGFVFNPLLWTWGISER
HHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEECCHHEECCCCCC
DMSVNYVTASVKQV
CCEEEEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA