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The map label for this gene is yggV [C]

Identifier: 89052696

GI number: 89052696

Start: 196892

End: 197503

Strand: Reverse

Name: yggV [C]

Synonym: Jann_0205

Alternate gene names: 89052696

Gene position: 197503-196892 (Counterclockwise)

Preceding gene: 89052697

Following gene: 89052695

Centisome position: 4.57

GC content: 58.82

Gene sequence:

>612_bases
ATGCGACGCTTTACCGGGGACCAACTTCTGATCGCGACCCACAATCAGGGCAAGCTGGACGAGATGCGGCATCTTTTGCA
GCCGTTTGGGATCCGCGTCTCCGGTGCCGCCGACCATGACTTGCCTGAGCCCGATGAAACCGAAACCACATTCGTCGGTA
ATGCCCGGATCAAAGCACATGCGGCGGCGAAGGCAACAGGATTGCCCGCGCTGAGTGATGATAGCGGGATCGAGATCGAT
GCTTTGGGCGGCGCGCCGGGGGTCTACACAGCGGATTGGGCCGAAACACCTGATGGACGGGATTTTGTTATGGCGATGGA
GCGGGCCCATCGTGAGTTGGAAGCTGTTGGAGCGTCCCACCCGCGAACGGCTCGGTTTTGCTGTACGCTTGTGCTGGCAT
GGCCCGATGGCCACGATGAAGTGTTTCCTGGTGTCATGGAAGGCCAGGTGGTCTGGCCCATGCGAGGCGAACAGGGTCAT
GGGTATGATCCAGTTTTCCAACCCAACGGCTATGACCTGACGTTTGGTGAAATGGATCGGTGGGAGAAGAACAAGATCAG
CCATCGGGCCCGCGCGGTCGAGCAGTTGGTAGAGATATTCAGTGACGGCTGA

Upstream 100 bases:

>100_bases
AGGGGGCGACGTTCTCCCGGGATGAGTTCAACGAACTTTACAGCCTGGCCGAAAAGGGTGTGGCAGAACTGGTTCAGGCG
CAGGCCGCGGCAACCGCCTG

Downstream 100 bases:

>100_bases
CTGGCAAGCGGGCGGCTTCGGCCTCTACGTCCATTGGCCGTTTTGCGAGGCGAAGTGCCCATATTGTGACTTCAACAGCC
ATGTCTCTGCGCGGATAGAT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRRFTGDQLLIATHNQGKLDEMRHLLQPFGIRVSGAADHDLPEPDETETTFVGNARIKAHAAAKATGLPALSDDSGIEID
ALGGAPGVYTADWAETPDGRDFVMAMERAHRELEAVGASHPRTARFCCTLVLAWPDGHDEVFPGVMEGQVVWPMRGEQGH
GYDPVFQPNGYDLTFGEMDRWEKNKISHRARAVEQLVEIFSDG

Sequences:

>Translated_203_residues
MRRFTGDQLLIATHNQGKLDEMRHLLQPFGIRVSGAADHDLPEPDETETTFVGNARIKAHAAAKATGLPALSDDSGIEID
ALGGAPGVYTADWAETPDGRDFVMAMERAHRELEAVGASHPRTARFCCTLVLAWPDGHDEVFPGVMEGQVVWPMRGEQGH
GYDPVFQPNGYDLTFGEMDRWEKNKISHRARAVEQLVEIFSDG
>Mature_203_residues
MRRFTGDQLLIATHNQGKLDEMRHLLQPFGIRVSGAADHDLPEPDETETTFVGNARIKAHAAAKATGLPALSDDSGIEID
ALGGAPGVYTADWAETPDGRDFVMAMERAHRELEAVGASHPRTARFCCTLVLAWPDGHDEVFPGVMEGQVVWPMRGEQGH
GYDPVFQPNGYDLTFGEMDRWEKNKISHRARAVEQLVEIFSDG

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=203, Percent_Identity=33.0049261083744, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI31657144, Length=171, Percent_Identity=35.0877192982456, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1789324, Length=200, Percent_Identity=35.5, Blast_Score=111, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17556833, Length=200, Percent_Identity=35, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322529, Length=201, Percent_Identity=27.363184079602, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920712, Length=195, Percent_Identity=34.3589743589744, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22366; Mature: 22366

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFTGDQLLIATHNQGKLDEMRHLLQPFGIRVSGAADHDLPEPDETETTFVGNARIKAH
CCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEECCCEEEEE
AAAKATGLPALSDDSGIEIDALGGAPGVYTADWAETPDGRDFVMAMERAHRELEAVGASH
HHHHHCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PRTARFCCTLVLAWPDGHDEVFPGVMEGQVVWPMRGEQGHGYDPVFQPNGYDLTFGEMDR
CCHHEEEEEEEEECCCCCHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEECCCCHH
WEKNKISHRARAVEQLVEIFSDG
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRFTGDQLLIATHNQGKLDEMRHLLQPFGIRVSGAADHDLPEPDETETTFVGNARIKAH
CCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEECCCEEEEE
AAAKATGLPALSDDSGIEIDALGGAPGVYTADWAETPDGRDFVMAMERAHRELEAVGASH
HHHHHCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PRTARFCCTLVLAWPDGHDEVFPGVMEGQVVWPMRGEQGHGYDPVFQPNGYDLTFGEMDR
CCHHEEEEEEEEECCCCCHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEECCCCHH
WEKNKISHRARAVEQLVEIFSDG
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA