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The map label for this gene is yggW [H]

Identifier: 89052695

GI number: 89052695

Start: 195745

End: 196902

Strand: Reverse

Name: yggW [H]

Synonym: Jann_0204

Alternate gene names: 89052695

Gene position: 196902-195745 (Counterclockwise)

Preceding gene: 89052696

Following gene: 89052688

Centisome position: 4.56

GC content: 57.6

Gene sequence:

>1158_bases
GTGACGGCTGACTGGCAAGCGGGCGGCTTCGGCCTCTACGTCCATTGGCCGTTTTGCGAGGCGAAGTGCCCATATTGTGA
CTTCAACAGCCATGTCTCTGCGCGGATAGATCAGGGTGCATGGTTGAAGGCCTATTTGAGTGAGCTGGACAGGGTGGCGG
CTGAACTGCCGAACCGAACCCTTGGCAGTGTCTTTTTTGGAGGTGGGACACCGTCCCTGATGGCACCGGATAGCGTGGCA
TCAATTATCGAGGCTGTGCGGCGGCTTTGGCCCGTGTCCAATGATCTTGAAGTGACACTTGAAGCAAATCCATCGTCCGT
CGAAGCCGGTCGCTTTGCAGGGTACAAGGACGCAGGCGTGAACCGCGTTTCCGTTGGGGTGCAAGCCCTGGATGATGTCG
ATCTGAAACGGCTTGGGCGGCTTCATTCGGTCAAAGAGGCCTATGCAGCGATTGATGTCGCGCGGGCTCATTTCGAGCGG
ATGAGTTTTGACCTGATTTATGCGCGCCAGGATCAAAGTCTTGCGGCCTGGCGCACAGAATTGACACAGGCATTGAATTT
GGCGGCCGACCACCTGTCCCTTTACCAGCTGACGATAGAGCCGGGCACGGCATTCGGTACGCGTCACGCGAAGGGCGGTT
TACGAGGCCTGCCCGAAGAAGACTTGAGTGCCGATATGTATGACCTGACCCAGGACCTATGCGGAGCCGCGGGACTTCCG
GCTTACGAGGTTTCAAATCACGCAGCGGATTTTGCGCAGTCTCGACATAATCTGGTGTACTGGCACGCAGGAGATTACGC
TGGGATTGGGCCCGGAGCCCATGGTCGCGTGACCTTGGCTGGACGTCGCTATGGGACAGAAACCTACCTGCAACCGCAGG
CGTGGTTGGATGCTGTGGGAAAAAGTGGGTCCGGAGAGAGTGATCGCACGGCCCTGTCAGCCCGCGAACAAGCGGAAGAG
TATCTGATGATGTCGCTGCGCTTGACGGAAGGGTCTGATCCCGCGCGGTATGAAGCCCTGAACGGCCAACCGCTTGACCC
GGTCAAGATACGCGACCTGGTTGATCTTGGCTTGATCGAGAGCACGCCTGAAAGGATCAAAGCAACCGCATGTGGGCGAC
CGGTGCTGAACGGAATTCTGAGAGATCTTTTAGCTTAG

Upstream 100 bases:

>100_bases
CCCAACGGCTATGACCTGACGTTTGGTGAAATGGATCGGTGGGAGAAGAACAAGATCAGCCATCGGGCCCGCGCGGTCGA
GCAGTTGGTAGAGATATTCA

Downstream 100 bases:

>100_bases
ATCTCAGTTTGTGTTCAGTAGTCGAAGCAGGTCGTCGAGTTGCGCCAAATCTTTGTATTTAATAGATAATTTACCTCCAC
CAGCATCAGTGTCATGATCA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTADWQAGGFGLYVHWPFCEAKCPYCDFNSHVSARIDQGAWLKAYLSELDRVAAELPNRTLGSVFFGGGTPSLMAPDSVA
SIIEAVRRLWPVSNDLEVTLEANPSSVEAGRFAGYKDAGVNRVSVGVQALDDVDLKRLGRLHSVKEAYAAIDVARAHFER
MSFDLIYARQDQSLAAWRTELTQALNLAADHLSLYQLTIEPGTAFGTRHAKGGLRGLPEEDLSADMYDLTQDLCGAAGLP
AYEVSNHAADFAQSRHNLVYWHAGDYAGIGPGAHGRVTLAGRRYGTETYLQPQAWLDAVGKSGSGESDRTALSAREQAEE
YLMMSLRLTEGSDPARYEALNGQPLDPVKIRDLVDLGLIESTPERIKATACGRPVLNGILRDLLA

Sequences:

>Translated_385_residues
MTADWQAGGFGLYVHWPFCEAKCPYCDFNSHVSARIDQGAWLKAYLSELDRVAAELPNRTLGSVFFGGGTPSLMAPDSVA
SIIEAVRRLWPVSNDLEVTLEANPSSVEAGRFAGYKDAGVNRVSVGVQALDDVDLKRLGRLHSVKEAYAAIDVARAHFER
MSFDLIYARQDQSLAAWRTELTQALNLAADHLSLYQLTIEPGTAFGTRHAKGGLRGLPEEDLSADMYDLTQDLCGAAGLP
AYEVSNHAADFAQSRHNLVYWHAGDYAGIGPGAHGRVTLAGRRYGTETYLQPQAWLDAVGKSGSGESDRTALSAREQAEE
YLMMSLRLTEGSDPARYEALNGQPLDPVKIRDLVDLGLIESTPERIKATACGRPVLNGILRDLLA
>Mature_384_residues
TADWQAGGFGLYVHWPFCEAKCPYCDFNSHVSARIDQGAWLKAYLSELDRVAAELPNRTLGSVFFGGGTPSLMAPDSVAS
IIEAVRRLWPVSNDLEVTLEANPSSVEAGRFAGYKDAGVNRVSVGVQALDDVDLKRLGRLHSVKEAYAAIDVARAHFERM
SFDLIYARQDQSLAAWRTELTQALNLAADHLSLYQLTIEPGTAFGTRHAKGGLRGLPEEDLSADMYDLTQDLCGAAGLPA
YEVSNHAADFAQSRHNLVYWHAGDYAGIGPGAHGRVTLAGRRYGTETYLQPQAWLDAVGKSGSGESDRTALSAREQAEEY
LMMSLRLTEGSDPARYEALNGQPLDPVKIRDLVDLGLIESTPERIKATACGRPVLNGILRDLLA

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=304, Percent_Identity=42.1052631578947, Blast_Score=234, Evalue=9e-62,
Organism=Escherichia coli, GI1789325, Length=381, Percent_Identity=37.007874015748, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI87082341, Length=215, Percent_Identity=25.1162790697674, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 41884; Mature: 41753

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADWQAGGFGLYVHWPFCEAKCPYCDFNSHVSARIDQGAWLKAYLSELDRVAAELPNRT
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
LGSVFFGGGTPSLMAPDSVASIIEAVRRLWPVSNDLEVTLEANPSSVEAGRFAGYKDAGV
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
NRVSVGVQALDDVDLKRLGRLHSVKEAYAAIDVARAHFERMSFDLIYARQDQSLAAWRTE
CEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
LTQALNLAADHLSLYQLTIEPGTAFGTRHAKGGLRGLPEEDLSADMYDLTQDLCGAAGLP
HHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCC
AYEVSNHAADFAQSRHNLVYWHAGDYAGIGPGAHGRVTLAGRRYGTETYLQPQAWLDAVG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHC
KSGSGESDRTALSAREQAEEYLMMSLRLTEGSDPARYEALNGQPLDPVKIRDLVDLGLIE
CCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHC
STPERIKATACGRPVLNGILRDLLA
CCHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TADWQAGGFGLYVHWPFCEAKCPYCDFNSHVSARIDQGAWLKAYLSELDRVAAELPNRT
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
LGSVFFGGGTPSLMAPDSVASIIEAVRRLWPVSNDLEVTLEANPSSVEAGRFAGYKDAGV
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
NRVSVGVQALDDVDLKRLGRLHSVKEAYAAIDVARAHFERMSFDLIYARQDQSLAAWRTE
CEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
LTQALNLAADHLSLYQLTIEPGTAFGTRHAKGGLRGLPEEDLSADMYDLTQDLCGAAGLP
HHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCCC
AYEVSNHAADFAQSRHNLVYWHAGDYAGIGPGAHGRVTLAGRRYGTETYLQPQAWLDAVG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHC
KSGSGESDRTALSAREQAEEYLMMSLRLTEGSDPARYEALNGQPLDPVKIRDLVDLGLIE
CCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCEECCCCCCCCCHHHHHHHHHHHHC
STPERIKATACGRPVLNGILRDLLA
CCHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]