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The map label for this gene is 89052582

Identifier: 89052582

GI number: 89052582

Start: 85871

End: 86794

Strand: Reverse

Name: 89052582

Synonym: Jann_0091

Alternate gene names: NA

Gene position: 86794-85871 (Counterclockwise)

Preceding gene: 89052583

Following gene: 89052581

Centisome position: 2.01

GC content: 65.48

Gene sequence:

>924_bases
ATGCTGATCATCAACAACCCCTCCGGCTTGCGCCACGAGATGCCCCAGGGCCACCCCGAACGCATCGCCAGGCTTGAGAC
GGTCTTCGCGGTCCTTGCCGACGTCAATGCCGAGCGAGTGGAGGCCCCTTTGGGCACCGAGGACGATGTCGCCCTGTGCC
ATCCGCAAGACTACATCGACGCGATGCGTGAGGCGCAGCCAGCGCAAGGCATGGTGCAGATCGACGCCGATACCAGCGCC
TCCCCGGGCACATGGGAGGCCGCCATGCGTGGCGTCGGCGGCTGTCTTCTGGCCGTGGACCGTGTGCTGTCGGGTGCCCA
TAAACGCGCCTTCGTGGCCACGCGCCCTCCAGGGCACCACGCTGAAAAGACCCGCGCCATGGGGTTTTGCCTGTTCGGCA
ACATCGCCATTGCCGCCCGCCACGCGTTGGAGCGCCATGGCCTGTCCCGGGTCGCCATCGTCGATTTTGACGTCCACCAC
GGCAACGGCACCCAGGATCTTCTGTGGGATGAGCCGCGCGCGCTGTTTGTCTCGTCCCACCAGATGCCGCTCTACCCCGG
ATCCGGCGCGGTCCATGAACGCGGCGCGTCCGATAATGTGCTGAACCTGCCGCTGCCGCCCGGGTCCGATGGGCAGGCGA
TGCGATCCCGCTACACATCCCACGTCTTTCCCCGTCTCCGGGACTGGCAGCCGGACCTGATCCTGATTTCCGCAGGATTT
GACGCCCATACCCGCGACCCGCTTGCCAATCTGCTATGGGAGGCTGAGGACTTCGCCTGGGTCACGCGCGAACTTGTGGC
CCTCGCGGAGGAGGTCTGCGAAGGCCGCATCGTCTCGACTCTCGAAGGCGGGTATGATCTGCAAGGCCTAGGCGACGGCG
TGCTCGCCCATGTGAGAGAGTTGGAGGATCGCGATGACGGATAA

Upstream 100 bases:

>100_bases
CAACACCTTGATAAAGTGGTATTTTCGCCATATTCAAATAATCTGCCTGCGGTGAACCGGCACCGCGCCCGTCAGGTCGA
CCAATGAGGCTTTCCGTTCC

Downstream 100 bases:

>100_bases
ACCCATCGATGAGATGAGCTTTGAGGACGCCATTCGCGAGCTGGAGCAGGTTGTCACGCAGCTGGACCGGGGCGATGTGG
CGCTGGAAGATTCCATCAAG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLIINNPSGLRHEMPQGHPERIARLETVFAVLADVNAERVEAPLGTEDDVALCHPQDYIDAMREAQPAQGMVQIDADTSA
SPGTWEAAMRGVGGCLLAVDRVLSGAHKRAFVATRPPGHHAEKTRAMGFCLFGNIAIAARHALERHGLSRVAIVDFDVHH
GNGTQDLLWDEPRALFVSSHQMPLYPGSGAVHERGASDNVLNLPLPPGSDGQAMRSRYTSHVFPRLRDWQPDLILISAGF
DAHTRDPLANLLWEAEDFAWVTRELVALAEEVCEGRIVSTLEGGYDLQGLGDGVLAHVRELEDRDDG

Sequences:

>Translated_307_residues
MLIINNPSGLRHEMPQGHPERIARLETVFAVLADVNAERVEAPLGTEDDVALCHPQDYIDAMREAQPAQGMVQIDADTSA
SPGTWEAAMRGVGGCLLAVDRVLSGAHKRAFVATRPPGHHAEKTRAMGFCLFGNIAIAARHALERHGLSRVAIVDFDVHH
GNGTQDLLWDEPRALFVSSHQMPLYPGSGAVHERGASDNVLNLPLPPGSDGQAMRSRYTSHVFPRLRDWQPDLILISAGF
DAHTRDPLANLLWEAEDFAWVTRELVALAEEVCEGRIVSTLEGGYDLQGLGDGVLAHVRELEDRDDG
>Mature_307_residues
MLIINNPSGLRHEMPQGHPERIARLETVFAVLADVNAERVEAPLGTEDDVALCHPQDYIDAMREAQPAQGMVQIDADTSA
SPGTWEAAMRGVGGCLLAVDRVLSGAHKRAFVATRPPGHHAEKTRAMGFCLFGNIAIAARHALERHGLSRVAIVDFDVHH
GNGTQDLLWDEPRALFVSSHQMPLYPGSGAVHERGASDNVLNLPLPPGSDGQAMRSRYTSHVFPRLRDWQPDLILISAGF
DAHTRDPLANLLWEAEDFAWVTRELVALAEEVCEGRIVSTLEGGYDLQGLGDGVLAHVRELEDRDDG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI17158039, Length=345, Percent_Identity=31.304347826087, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI30795202, Length=345, Percent_Identity=31.304347826087, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI30795204, Length=345, Percent_Identity=31.304347826087, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI20070354, Length=306, Percent_Identity=33.9869281045752, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI153085395, Length=247, Percent_Identity=37.6518218623482, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI62750347, Length=324, Percent_Identity=31.4814814814815, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI62750349, Length=324, Percent_Identity=31.4814814814815, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI13128864, Length=306, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI148539870, Length=246, Percent_Identity=37.8048780487805, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI169234807, Length=251, Percent_Identity=37.4501992031873, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI226529806, Length=305, Percent_Identity=31.4754098360656, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI13128862, Length=245, Percent_Identity=28.1632653061224, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI13128860, Length=251, Percent_Identity=25.0996015936255, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI293336691, Length=252, Percent_Identity=24.6031746031746, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17540334, Length=318, Percent_Identity=31.7610062893082, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17540332, Length=317, Percent_Identity=31.8611987381703, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=317, Percent_Identity=31.8611987381703, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193209491, Length=339, Percent_Identity=31.5634218289086, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25154020, Length=274, Percent_Identity=32.4817518248175, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI25154022, Length=272, Percent_Identity=31.6176470588235, Blast_Score=130, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17537347, Length=293, Percent_Identity=29.6928327645051, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534739, Length=255, Percent_Identity=25.4901960784314, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=251, Percent_Identity=25.0996015936255, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=216, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=316, Percent_Identity=28.1645569620253, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325141, Length=312, Percent_Identity=25, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6323999, Length=252, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321244, Length=252, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325325, Length=125, Percent_Identity=29.6, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281360899, Length=304, Percent_Identity=32.8947368421053, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24642144, Length=304, Percent_Identity=32.8947368421053, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24642142, Length=304, Percent_Identity=32.8947368421053, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24642146, Length=304, Percent_Identity=32.8947368421053, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24641720, Length=321, Percent_Identity=32.0872274143302, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360799, Length=321, Percent_Identity=32.0872274143302, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360801, Length=321, Percent_Identity=32.0872274143302, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24657891, Length=252, Percent_Identity=26.5873015873016, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644244, Length=253, Percent_Identity=23.7154150197628, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33500; Mature: 33500

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIINNPSGLRHEMPQGHPERIARLETVFAVLADVNAERVEAPLGTEDDVALCHPQDYID
CEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCHHHHH
AMREAQPAQGMVQIDADTSASPGTWEAAMRGVGGCLLAVDRVLSGAHKRAFVATRPPGHH
HHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHCEEEEECCCCCC
AEKTRAMGFCLFGNIAIAARHALERHGLSRVAIVDFDVHHGNGTQDLLWDEPRALFVSSH
HHHHHHHEEHHHCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEECC
QMPLYPGSGAVHERGASDNVLNLPLPPGSDGQAMRSRYTSHVFPRLRDWQPDLILISAGF
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCC
DAHTRDPLANLLWEAEDFAWVTRELVALAEEVCEGRIVSTLEGGYDLQGLGDGVLAHVRE
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCHHHHHHHHH
LEDRDDG
HHCCCCC
>Mature Secondary Structure
MLIINNPSGLRHEMPQGHPERIARLETVFAVLADVNAERVEAPLGTEDDVALCHPQDYID
CEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCHHHHH
AMREAQPAQGMVQIDADTSASPGTWEAAMRGVGGCLLAVDRVLSGAHKRAFVATRPPGHH
HHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHCEEEEECCCCCC
AEKTRAMGFCLFGNIAIAARHALERHGLSRVAIVDFDVHHGNGTQDLLWDEPRALFVSSH
HHHHHHHEEHHHCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEECC
QMPLYPGSGAVHERGASDNVLNLPLPPGSDGQAMRSRYTSHVFPRLRDWQPDLILISAGF
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCC
DAHTRDPLANLLWEAEDFAWVTRELVALAEEVCEGRIVSTLEGGYDLQGLGDGVLAHVRE
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCHHHHHHHHH
LEDRDDG
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]