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The map label for this gene is phoB [H]

Identifier: 89052562

GI number: 89052562

Start: 65165

End: 66445

Strand: Direct

Name: phoB [H]

Synonym: Jann_0071

Alternate gene names: 89052562

Gene position: 65165-66445 (Clockwise)

Preceding gene: 89052560

Following gene: 89052564

Centisome position: 1.51

GC content: 61.83

Gene sequence:

>1281_bases
ATGGGGGCATCACTTCCCAAAGTAGCGGCGGGTCGCCCCGCGGCCGTGGACCCGGAGCCAGACGCGCTGACCGTGTTGGT
GTTGGATGACAGCCCCGCGCAGCGCAACATGGTGTGCGCGCTACTGCGCCGTTGGGGGCATACGGCCATATCAACCGGCG
ATCCGGTGGAAGCGCTGGCCCGCGCGCGGGAACCGGACATCTCCTTGATTCTGTGCGACTGGATGATGCCGGAGATGACG
GGGCCGGAGTTCTGTCATCGCCTGAGGTCGGAGGTGACGGACACCTATCCTTATGTTTTGCTGCTCACCTCCAACACCGA
CCGGGGGGCCGTAGCCGAAGGGCTCGCGGCCGGCGCGGATGACTTCCTCAACAAACCCGTGCGTCCGCCAGAGTTGCAGG
CCCGCATGAATGCCGGCGCGCGCATCGTTGCCATGCAGCAGGAACTGCGCGCCAAGAACGGGTTGCTGGAAACGACGCTG
GACGAGTTGCAGTTGCTCTACGATGCCATTGACCGTGACCTTGATGAGGCGCGGCGCCTGCAAATGGCGTCCTTGCAAGA
CACTCACCGTCCGTTCAAAGGCGGTGACGTATCGTTGCTGTTGGAGGCCAGCGGTCATGTCGGCGGCGACATGGTGGGAT
ATTTCAACGTGACCGACGACACGATTGGCCTGTTCAGTCTGGATGTGTCGGGGCACGGGGTTGCGTCGGCCATGTTGGCC
GCGCGTACAGCCGGGATGCTGTCAGAGGCCTCGCCCGACCAGAACATCGCGATGGAACGGGGCCCGGATGGGCAGTTCTT
TGACCTCCCGCCCGATATCGCCGTTGGCCGTATGAACGATCTGCTGCTGAAAGAGGTTCAGACGGATCGCTATTTCACCA
TCTGCATCGCGTTTGCTAACCTGAAGACTGGCCTCTTGCGGATCGTGCAGGCTGGCCATCCACACCCGATGGTTCTGCGC
GCGACCGGCCAGGTCGACATGGTCGGCGACGGTGGCCCACCCGTGGGTTTGCTGCCCAATATGCCCTTCACTTCGTTTGA
GCTTCAATTGAACCCCGGCGACAGGGTGCTGATGTACTCCGATGGCCTGACGGAATGCCCCAACGTCCAAGGTGACATGC
TGGACGACGACGGCCTGATCGACTTGATGAAAAAGAACAAATCCGAAGAAAACGTGGCGTTTCTGTCGGCACTGCGGGAC
GGTTTGGTGGATTTCGCAGGCACGACGGATTTTCCCGACGACCTCTCAGCCCTGCTGTTCTCCTTCCGCGGGGCCCCATA
A

Upstream 100 bases:

>100_bases
AACAAAGTGATGTCTTGCGGCCGATAACGTTTCAAATTTTCCAGTTCATGGCCCATTAAAGAATTCGGCCCATGGTCCTT
GGAAATAGCTGAGGACAAGC

Downstream 100 bases:

>100_bases
GGCGACGGGCGAAGGTCGGAGCCGCCTTGCCCCCTACGCTCCCGCCAGATATCGCGCGACGAAATGGCGATCACCCGCAA
CGGCCAGCTTGTCCAAAGCC

Product: response regulator receiver (CheY-like) modulated serine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MGASLPKVAAGRPAAVDPEPDALTVLVLDDSPAQRNMVCALLRRWGHTAISTGDPVEALARAREPDISLILCDWMMPEMT
GPEFCHRLRSEVTDTYPYVLLLTSNTDRGAVAEGLAAGADDFLNKPVRPPELQARMNAGARIVAMQQELRAKNGLLETTL
DELQLLYDAIDRDLDEARRLQMASLQDTHRPFKGGDVSLLLEASGHVGGDMVGYFNVTDDTIGLFSLDVSGHGVASAMLA
ARTAGMLSEASPDQNIAMERGPDGQFFDLPPDIAVGRMNDLLLKEVQTDRYFTICIAFANLKTGLLRIVQAGHPHPMVLR
ATGQVDMVGDGGPPVGLLPNMPFTSFELQLNPGDRVLMYSDGLTECPNVQGDMLDDDGLIDLMKKNKSEENVAFLSALRD
GLVDFAGTTDFPDDLSALLFSFRGAP

Sequences:

>Translated_426_residues
MGASLPKVAAGRPAAVDPEPDALTVLVLDDSPAQRNMVCALLRRWGHTAISTGDPVEALARAREPDISLILCDWMMPEMT
GPEFCHRLRSEVTDTYPYVLLLTSNTDRGAVAEGLAAGADDFLNKPVRPPELQARMNAGARIVAMQQELRAKNGLLETTL
DELQLLYDAIDRDLDEARRLQMASLQDTHRPFKGGDVSLLLEASGHVGGDMVGYFNVTDDTIGLFSLDVSGHGVASAMLA
ARTAGMLSEASPDQNIAMERGPDGQFFDLPPDIAVGRMNDLLLKEVQTDRYFTICIAFANLKTGLLRIVQAGHPHPMVLR
ATGQVDMVGDGGPPVGLLPNMPFTSFELQLNPGDRVLMYSDGLTECPNVQGDMLDDDGLIDLMKKNKSEENVAFLSALRD
GLVDFAGTTDFPDDLSALLFSFRGAP
>Mature_425_residues
GASLPKVAAGRPAAVDPEPDALTVLVLDDSPAQRNMVCALLRRWGHTAISTGDPVEALARAREPDISLILCDWMMPEMTG
PEFCHRLRSEVTDTYPYVLLLTSNTDRGAVAEGLAAGADDFLNKPVRPPELQARMNAGARIVAMQQELRAKNGLLETTLD
ELQLLYDAIDRDLDEARRLQMASLQDTHRPFKGGDVSLLLEASGHVGGDMVGYFNVTDDTIGLFSLDVSGHGVASAMLAA
RTAGMLSEASPDQNIAMERGPDGQFFDLPPDIAVGRMNDLLLKEVQTDRYFTICIAFANLKTGLLRIVQAGHPHPMVLRA
TGQVDMVGDGGPPVGLLPNMPFTSFELQLNPGDRVLMYSDGLTECPNVQGDMLDDDGLIDLMKKNKSEENVAFLSALRDG
LVDFAGTTDFPDDLSALLFSFRGAP

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=123, Percent_Identity=34.9593495934959, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 46038; Mature: 45907

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASLPKVAAGRPAAVDPEPDALTVLVLDDSPAQRNMVCALLRRWGHTAISTGDPVEALA
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHH
RAREPDISLILCDWMMPEMTGPEFCHRLRSEVTDTYPYVLLLTSNTDRGAVAEGLAAGAD
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCH
DFLNKPVRPPELQARMNAGARIVAMQQELRAKNGLLETTLDELQLLYDAIDRDLDEARRL
HHHCCCCCCHHHHHHHCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
QMASLQDTHRPFKGGDVSLLLEASGHVGGDMVGYFNVTDDTIGLFSLDVSGHGVASAMLA
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHH
ARTAGMLSEASPDQNIAMERGPDGQFFDLPPDIAVGRMNDLLLKEVQTDRYFTICIAFAN
HHHHHHHHCCCCCCCEEEECCCCCCEECCCCCCHHCCHHHHHHHHHCCCCEEEEEEEHHH
LKTGLLRIVQAGHPHPMVLRATGQVDMVGDGGPPVGLLPNMPFTSFELQLNPGDRVLMYS
HHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEC
DGLTECPNVQGDMLDDDGLIDLMKKNKSEENVAFLSALRDGLVDFAGTTDFPDDLSALLF
CCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SFRGAP
HHCCCC
>Mature Secondary Structure 
GASLPKVAAGRPAAVDPEPDALTVLVLDDSPAQRNMVCALLRRWGHTAISTGDPVEALA
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHH
RAREPDISLILCDWMMPEMTGPEFCHRLRSEVTDTYPYVLLLTSNTDRGAVAEGLAAGAD
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCH
DFLNKPVRPPELQARMNAGARIVAMQQELRAKNGLLETTLDELQLLYDAIDRDLDEARRL
HHHCCCCCCHHHHHHHCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
QMASLQDTHRPFKGGDVSLLLEASGHVGGDMVGYFNVTDDTIGLFSLDVSGHGVASAMLA
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHH
ARTAGMLSEASPDQNIAMERGPDGQFFDLPPDIAVGRMNDLLLKEVQTDRYFTICIAFAN
HHHHHHHHCCCCCCCEEEECCCCCCEECCCCCCHHCCHHHHHHHHHCCCCEEEEEEEHHH
LKTGLLRIVQAGHPHPMVLRATGQVDMVGDGGPPVGLLPNMPFTSFELQLNPGDRVLMYS
HHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEC
DGLTECPNVQGDMLDDDGLIDLMKKNKSEENVAFLSALRDGLVDFAGTTDFPDDLSALLF
CCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SFRGAP
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]