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The map label for this gene is dapA [H]

Identifier: 89052524

GI number: 89052524

Start: 30186

End: 31061

Strand: Reverse

Name: dapA [H]

Synonym: Jann_0033

Alternate gene names: 89052524

Gene position: 31061-30186 (Counterclockwise)

Preceding gene: 89052529

Following gene: 89052523

Centisome position: 0.72

GC content: 61.76

Gene sequence:

>876_bases
ATGATGTTCCAAGGCTCGATGCCCGCTCTGGTCACTCCGATGACAAATGGTGCTGTGGACTTTGAGGTGCTGAAACGTCT
GGTCGACTGGCATGTGGAGGAAGGCTCCAACGGGTTGGTGCCTGTGGGGACGACGGGTGAAAGCCCCACGCTGACCCATG
AAGAGCATGAGCAGGTGATTGAGACGGTCGTGAAGGCCGCCGGTGGCCGCGTTCCGGTGATCGCGGGCGCGGGGTCAAAC
AACACGGCAGAGGCGATGCGCCATGTGCAACATGCCAAGGATGTGGGGGCTGATGCCACGCTTGTGGTGACGCCTTATTA
CAACAAGCCGACGCAGCGTGGGTTGATCGCCCATTACGAGGCGTTGGCCGAGGTCGGCATCCCGATTTTCATCTACAACA
TTCCGGGTCGGTCTGTGGTTGATATGACGCCCGAGACGATGGGCGAGCTGGCAAAGCACCCAATGATCATCGGCGTGAAG
GACGCGACGGCGGACATGGCGCGGGTATCCAGGCAGCGCGAAACCTGCGGCACGGATTTCGTGCAAATGTCCGCGGAAGA
TGCCAGCGCACTGGGCTTCAACGCCCATGGCGGTGTGGGGTGTATCAGCGTCACGGCCAACGTTGCGCCGAAGTTGTGCG
CGGAATTTCAGGCGGCCATGGGGGCAGGCGACTATACCGAAGCACTGGCGTATCAGGATCGCCTGATGCCGCTTCACAAT
GCGATCTTCACGGAGCCGGGCCTCTGCGGCGTGAAATATGCGATGTCGGTGCTGGGCCTATGCTCGGACGAGGTGCGTTT
GCCGTTGGTGGGCGTCGACGAGTCCACCAAGGCCGCGATTGAGGCGGCACTGCGCCACGCGGGCCTGCTGTCGTGA

Upstream 100 bases:

>100_bases
CAAACCCAAGGAAGCAACTCACGAACTTGGCAATTCTGCACGAGCCTTGTATTGGGGCGGGAAATTGCCGTCTCCCTCAC
CTTTCCATGCAAGGACGCGA

Downstream 100 bases:

>100_bases
CATCCCCCCCGGACGCCCCCGAGGGCTCCGTCAAACGTCTGATCCAGATCCTGTCGGTGACGAATTTCGTCATCGGTATG
GGGGCGTTTATGGTCATCGG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MMFQGSMPALVTPMTNGAVDFEVLKRLVDWHVEEGSNGLVPVGTTGESPTLTHEEHEQVIETVVKAAGGRVPVIAGAGSN
NTAEAMRHVQHAKDVGADATLVVTPYYNKPTQRGLIAHYEALAEVGIPIFIYNIPGRSVVDMTPETMGELAKHPMIIGVK
DATADMARVSRQRETCGTDFVQMSAEDASALGFNAHGGVGCISVTANVAPKLCAEFQAAMGAGDYTEALAYQDRLMPLHN
AIFTEPGLCGVKYAMSVLGLCSDEVRLPLVGVDESTKAAIEAALRHAGLLS

Sequences:

>Translated_291_residues
MMFQGSMPALVTPMTNGAVDFEVLKRLVDWHVEEGSNGLVPVGTTGESPTLTHEEHEQVIETVVKAAGGRVPVIAGAGSN
NTAEAMRHVQHAKDVGADATLVVTPYYNKPTQRGLIAHYEALAEVGIPIFIYNIPGRSVVDMTPETMGELAKHPMIIGVK
DATADMARVSRQRETCGTDFVQMSAEDASALGFNAHGGVGCISVTANVAPKLCAEFQAAMGAGDYTEALAYQDRLMPLHN
AIFTEPGLCGVKYAMSVLGLCSDEVRLPLVGVDESTKAAIEAALRHAGLLS
>Mature_291_residues
MMFQGSMPALVTPMTNGAVDFEVLKRLVDWHVEEGSNGLVPVGTTGESPTLTHEEHEQVIETVVKAAGGRVPVIAGAGSN
NTAEAMRHVQHAKDVGADATLVVTPYYNKPTQRGLIAHYEALAEVGIPIFIYNIPGRSVVDMTPETMGELAKHPMIIGVK
DATADMARVSRQRETCGTDFVQMSAEDASALGFNAHGGVGCISVTANVAPKLCAEFQAAMGAGDYTEALAYQDRLMPLHN
AIFTEPGLCGVKYAMSVLGLCSDEVRLPLVGVDESTKAAIEAALRHAGLLS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=291, Percent_Identity=27.8350515463918, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI13540533, Length=304, Percent_Identity=28.6184210526316, Blast_Score=98, Evalue=7e-21,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=47.945205479452, Blast_Score=264, Evalue=4e-72,
Organism=Escherichia coli, GI87082415, Length=297, Percent_Identity=30.3030303030303, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786463, Length=283, Percent_Identity=30.3886925795053, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789620, Length=291, Percent_Identity=30.9278350515464, Blast_Score=104, Evalue=6e-24,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 30760; Mature: 30760

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFQGSMPALVTPMTNGAVDFEVLKRLVDWHVEEGSNGLVPVGTTGESPTLTHEEHEQVI
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHH
ETVVKAAGGRVPVIAGAGSNNTAEAMRHVQHAKDVGADATLVVTPYYNKPTQRGLIAHYE
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
ALAEVGIPIFIYNIPGRSVVDMTPETMGELAKHPMIIGVKDATADMARVSRQRETCGTDF
HHHHCCCEEEEEECCCCCEECCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCHH
VQMSAEDASALGFNAHGGVGCISVTANVAPKLCAEFQAAMGAGDYTEALAYQDRLMPLHN
HHCCCCCHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AIFTEPGLCGVKYAMSVLGLCSDEVRLPLVGVDESTKAAIEAALRHAGLLS
HHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMFQGSMPALVTPMTNGAVDFEVLKRLVDWHVEEGSNGLVPVGTTGESPTLTHEEHEQVI
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHH
ETVVKAAGGRVPVIAGAGSNNTAEAMRHVQHAKDVGADATLVVTPYYNKPTQRGLIAHYE
HHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
ALAEVGIPIFIYNIPGRSVVDMTPETMGELAKHPMIIGVKDATADMARVSRQRETCGTDF
HHHHCCCEEEEEECCCCCEECCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCHH
VQMSAEDASALGFNAHGGVGCISVTANVAPKLCAEFQAAMGAGDYTEALAYQDRLMPLHN
HHCCCCCHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AIFTEPGLCGVKYAMSVLGLCSDEVRLPLVGVDESTKAAIEAALRHAGLLS
HHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA