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The map label for this gene is pncB [H]

Identifier: 89052513

GI number: 89052513

Start: 21276

End: 22568

Strand: Direct

Name: pncB [H]

Synonym: Jann_0022

Alternate gene names: 89052513

Gene position: 21276-22568 (Clockwise)

Preceding gene: 89052507

Following gene: 89052525

Centisome position: 0.49

GC content: 61.56

Gene sequence:

>1293_bases
ATGGTCGATATCGCCACCCGCGTCTGGAACCACAAATGGAAGATCGACCCGATCGTCCGGTCCCTGATCGACACGGATTT
CTACAAACTGCTGATGTGTCAGTCCGTCTTTCGCAACAAGCCCGACACGCAGGTGCGCTTTTCGCTGATCAACCGCACCA
CGCGCATTCCCCTCGCCGACCTTATTGACGAAGGCGAGCTTCGCGAACAGCTGGACCACATCCGCACCCTCCGCCTCACC
CGCGGCGAGTCGACCTGGATGCGCGGCAACACCTTCTACGGTCAGCGGCAGATGTTCTCGCCCGAATTCATGGATTGGTT
TGAGGCCCTGCAACTCCCCCCCTATCATCTGGAGCGGGTCGGCGATCAGTATGAGCTGACGTTTGAAGGTGCCTGGCCCG
AGGTCATGCTGTGGGAAATCCCCGCGCTGTCGGTGTTGATGGAGCTTCGCGGTCGTGCCGTCCTCGGCACCATGGGCCGG
TTTGAACTTCAGGTCCTCTATGCCCGCGCCATGACCAAACTGTGGGAAAAGATCGAACGCCTCAAGGACATCCCCGACCT
GCGCGTCGCTGATTTCGGCACCCGGCGGCGGCATTCCTTCCTCTGGCAGGATTGGGCCGTCCGCGCGATGGACGAGGGCT
TGGGTGATAACTTCACCGGCACCTCTAACTGCCTCATTGCCAAGAACCGCGATCTGGAGGCGATCGGCACCAACGCCCAC
GAACTCCCCATGGTTTACGCCGCTTTGGCCGACAGCGACGAGGCCCTCTTCACCGCCCCCTACGACGTGCTGTCCGACTG
GCATGAAGAGCATTCCGGCAATTTGCGCATCATCCTGCCCGACACCTACGGCACGCAAGGCTTCCTCGACAACGCGCCGG
ATTGGCTGGCCGGTTGGACCGGGATCAGGATCGACTCCGGCGACCCAGCGACGGCGGCGGAAGTGGCCATCGCCTGGTGG
AAAAGCCGTGGCGAAGACCCCCGGTCAAAGCTGGTGATATTCTCCGACGGGCTGGACGTCGACAAGATCGAGACTCTTCA
CAAACAATTCTCAGGTCGCGTGCGGGTCAGCTTCGGCTGGGGCACTTTGCTGACGAACGACTTCCGAGGCCTCGTCACAA
ACGACGCCCTCGCCCCGTTCAGCCTGGTCTGCAAAGCGGTGAGCGCAAACGGACGCCCCACCGTCAAACTCAGCGACAAC
CCCGAAAAGGCCATGGGGCCTGCGGATCAGATCGAGCGGTATAAGCGGGTGTTCGGGGTTGGCGAGCAGGAACGGGTGGA
GGTGGTGGTTTAA

Upstream 100 bases:

>100_bases
GCGCTCAGGTTGCGTTGCCGCCTGGCCTGGCCCCGCGCCGCCAACCTTGCCTCCCCGTGCCACTCTTGCTCTAACGTCCC
CGACAACCGGAGAGAGAGCC

Downstream 100 bases:

>100_bases
AGATCGTCGTCAAAAAGCGAATTAGTCCCCTCGCCAATGTCCTTCACAGTAAGGTCGAGTATGTGGCCCAACTGAGTGCG
CGTAAGTTCCGGAGACACTG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTQVRFSLINRTTRIPLADLIDEGELREQLDHIRTLRLT
RGESTWMRGNTFYGQRQMFSPEFMDWFEALQLPPYHLERVGDQYELTFEGAWPEVMLWEIPALSVLMELRGRAVLGTMGR
FELQVLYARAMTKLWEKIERLKDIPDLRVADFGTRRRHSFLWQDWAVRAMDEGLGDNFTGTSNCLIAKNRDLEAIGTNAH
ELPMVYAALADSDEALFTAPYDVLSDWHEEHSGNLRIILPDTYGTQGFLDNAPDWLAGWTGIRIDSGDPATAAEVAIAWW
KSRGEDPRSKLVIFSDGLDVDKIETLHKQFSGRVRVSFGWGTLLTNDFRGLVTNDALAPFSLVCKAVSANGRPTVKLSDN
PEKAMGPADQIERYKRVFGVGEQERVEVVV

Sequences:

>Translated_430_residues
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTQVRFSLINRTTRIPLADLIDEGELREQLDHIRTLRLT
RGESTWMRGNTFYGQRQMFSPEFMDWFEALQLPPYHLERVGDQYELTFEGAWPEVMLWEIPALSVLMELRGRAVLGTMGR
FELQVLYARAMTKLWEKIERLKDIPDLRVADFGTRRRHSFLWQDWAVRAMDEGLGDNFTGTSNCLIAKNRDLEAIGTNAH
ELPMVYAALADSDEALFTAPYDVLSDWHEEHSGNLRIILPDTYGTQGFLDNAPDWLAGWTGIRIDSGDPATAAEVAIAWW
KSRGEDPRSKLVIFSDGLDVDKIETLHKQFSGRVRVSFGWGTLLTNDFRGLVTNDALAPFSLVCKAVSANGRPTVKLSDN
PEKAMGPADQIERYKRVFGVGEQERVEVVV
>Mature_430_residues
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTQVRFSLINRTTRIPLADLIDEGELREQLDHIRTLRLT
RGESTWMRGNTFYGQRQMFSPEFMDWFEALQLPPYHLERVGDQYELTFEGAWPEVMLWEIPALSVLMELRGRAVLGTMGR
FELQVLYARAMTKLWEKIERLKDIPDLRVADFGTRRRHSFLWQDWAVRAMDEGLGDNFTGTSNCLIAKNRDLEAIGTNAH
ELPMVYAALADSDEALFTAPYDVLSDWHEEHSGNLRIILPDTYGTQGFLDNAPDWLAGWTGIRIDSGDPATAAEVAIAWW
KSRGEDPRSKLVIFSDGLDVDKIETLHKQFSGRVRVSFGWGTLLTNDFRGLVTNDALAPFSLVCKAVSANGRPTVKLSDN
PEKAMGPADQIERYKRVFGVGEQERVEVVV

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=404, Percent_Identity=33.4158415841584, Blast_Score=180, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324783, Length=433, Percent_Identity=29.3302540415704, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 49188; Mature: 49188

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTQVRFSLINRTTRIPLAD
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHH
LIDEGELREQLDHIRTLRLTRGESTWMRGNTFYGQRQMFSPEFMDWFEALQLPPYHLERV
HHCCCHHHHHHHHHHHHEEECCCCCEECCCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHC
GDQYELTFEGAWPEVMLWEIPALSVLMELRGRAVLGTMGRFELQVLYARAMTKLWEKIER
CCCEEEEECCCCCCEEEECCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
LKDIPDLRVADFGTRRRHSFLWQDWAVRAMDEGLGDNFTGTSNCLIAKNRDLEAIGTNAH
HHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCCCH
ELPMVYAALADSDEALFTAPYDVLSDWHEEHSGNLRIILPDTYGTQGFLDNAPDWLAGWT
HHHHHEEECCCCCCEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHCCC
GIRIDSGDPATAAEVAIAWWKSRGEDPRSKLVIFSDGLDVDKIETLHKQFSGRVRVSFGW
EEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECC
GTLLTNDFRGLVTNDALAPFSLVCKAVSANGRPTVKLSDNPEKAMGPADQIERYKRVFGV
CHHHHCCCCCEECCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHCCCHHHHHHHHHHHCC
GEQERVEVVV
CCCCCEEEEC
>Mature Secondary Structure
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTQVRFSLINRTTRIPLAD
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHH
LIDEGELREQLDHIRTLRLTRGESTWMRGNTFYGQRQMFSPEFMDWFEALQLPPYHLERV
HHCCCHHHHHHHHHHHHEEECCCCCEECCCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHC
GDQYELTFEGAWPEVMLWEIPALSVLMELRGRAVLGTMGRFELQVLYARAMTKLWEKIER
CCCEEEEECCCCCCEEEECCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
LKDIPDLRVADFGTRRRHSFLWQDWAVRAMDEGLGDNFTGTSNCLIAKNRDLEAIGTNAH
HHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCCCH
ELPMVYAALADSDEALFTAPYDVLSDWHEEHSGNLRIILPDTYGTQGFLDNAPDWLAGWT
HHHHHEEECCCCCCEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHCCC
GIRIDSGDPATAAEVAIAWWKSRGEDPRSKLVIFSDGLDVDKIETLHKQFSGRVRVSFGW
EEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECC
GTLLTNDFRGLVTNDALAPFSLVCKAVSANGRPTVKLSDNPEKAMGPADQIERYKRVFGV
CHHHHCCCCCEECCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHCCCHHHHHHHHHHHCC
GEQERVEVVV
CCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA