Click here to switch to the map view.

The map label for this gene is proS

Identifier: 88658467

GI number: 88658467

Start: 630982

End: 631107

Strand: Reverse

Name: proS

Synonym: ECH_0624

Alternate gene names: 88658467

Gene position: 631107-630982 (Counterclockwise)

Preceding gene: 88657976

Following gene: 88658538

Centisome position: 53.65

GC content: 25.4

Gene sequence:

>126_bases
ATGCCATGGCAAGTTATAATTGGTAAATCAACAGTAGAACAAGACCTTATTGAAGTAAGGAATAGATTAACAAAAGATAA
AGTTTTAATTTCCACAGAACAATTCTTAAATAAATTAAAAAAATGA

Upstream 100 bases:

>100_bases
AAAGCTAGTTTGATGTTATGTAATAAAATGGTTTTTATAGTTATGTAATTAAGTTGATGATAGTCCTGGTATTAAGTTAG
CAAGAACAGATCTGCTAGGT

Downstream 100 bases:

>100_bases
TACTAGGGATTGGTGCAGACATTGTTTATGTTCCTCGTATATCAAATTTATGGAAAAAATTTGGTACTAAATTTCTTAAA
CGGGTATTTAGTGAAAAAGA

Product: prolyl-tRNA synthetase, truncation

Products: NA

Alternate protein names: Proline--tRNA ligase; ProRS

Number of amino acids: Translated: 41; Mature: 40

Protein sequence:

>41_residues
MPWQVIIGKSTVEQDLIEVRNRLTKDKVLISTEQFLNKLKK

Sequences:

>Translated_41_residues
MPWQVIIGKSTVEQDLIEVRNRLTKDKVLISTEQFLNKLKK
>Mature_40_residues
PWQVIIGKSTVEQDLIEVRNRLTKDKVLISTEQFLNKLKK

Specific function: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction:proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYP_EHRCR (Q2GG92)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507541.1
- ProteinModelPortal:   Q2GG92
- SMR:   Q2GG92
- STRING:   Q2GG92
- GeneID:   3927018
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0740
- TIGR:   ECH_0740
- eggNOG:   COG0442
- HOGENOM:   HBG403504
- OMA:   DFVLGPT
- PhylomeDB:   Q2GG92
- ProtClustDB:   PRK12325
- BioCyc:   ECHA205920:ECH_0740-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01570
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR002316
- InterPro:   IPR004500
- Gene3D:   G3DSA:3.40.50.800
- PRINTS:   PR01046
- TIGRFAMs:   TIGR00409

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; SSF52954 Anticodon_bd

EC number: =6.1.1.15

Molecular weight: Translated: 4841; Mature: 4710

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWQVIIGKSTVEQDLIEVRNRLTKDKVLISTEQFLNKLKK
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PWQVIIGKSTVEQDLIEVRNRLTKDKVLISTEQFLNKLKK
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA