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The map label for this gene is xerC [H]

Identifier: 88658398

GI number: 88658398

Start: 331351

End: 332286

Strand: Direct

Name: xerC [H]

Synonym: ECH_0341

Alternate gene names: 88658398

Gene position: 331351-332286 (Clockwise)

Preceding gene: 88657684

Following gene: 88658030

Centisome position: 28.17

GC content: 30.77

Gene sequence:

>936_bases
ATGAAAGATCAAAAGCTGTGTATTGTTGTAAATGAATGGGTGTCTTGGATAAAAAAAGAAAGAAGATATGCGACTAATAC
TGTTGATTCTTATCTAAGAGATGTTAATAAGTTTATTGAGTTTTTGTATATGTGTGTTTTGCGTCCTGTTACTTTAGAGG
ATATTATTGGTGTAAAAGTTGCAGATTTAAGGAAATGGTTTGCATTTAGATACCAGGCTAATATAGAAGCTGTAACAAAT
GCAAGATCTTTGTCAGCATTGAAAAATTTTTTTCGGTATTTGTCACGTACTTATAATATAGATGGTCAAGCAGTGTTTTG
TTTATCTAGACCAAAACTTAAAAGTACTTTACCTAGAACATTAACTCAATCTCACATTCAAAAAATAATAGATTATTATG
CGTTATTAGATACCGATTGGATAGTCAAGCGTGATTTTGCACTAATTGTGCTCCTCTATGGATGTGGTTTGAGAATTAGT
GAGGCAGTGAATTTAAAGTTTCAGAATATTAGAAGAGAGGAGCTTTTAATTATTGGGAAAAGAAGTAAGGAAAGGATCTT
ACCTATTTTGCCTATAGTACGTCAAAGTTTAGATGAGTATGTAAGGTGTTGTCCATATCATATGGAATTGAACTCAGTTA
AAAATGAATATGTTTTTGTAGGAGTTAGAGGCAAAAAACTTAAAAGGACTTATTTTGCAAATAGAATACAAAAGATTTGT
AAAGAAATAGGGTTGCCTGATGTTATAACTCCTCATGCATTTCGTCATAGTTTTGCAACACATTTATTTCTAGGTGGTGC
GGATATTAGATCAATACAAGAATTGTTAGGCCATGCTAATTTATCAACTACGCAAATTTATACTCATTTAGATCATAAAA
GTGTTATAGATCATTATAAGAATTTCCATCCTCAAGTTATAAAAAAGAATAGTTGA

Upstream 100 bases:

>100_bases
TATTGGTAATAAACATTTAAAATATTAGCAGGGATAATTTAATATTCTACATTTTGTGTTTTTATAATTTGCGTCTATTA
TAGGTTAAAATTTTTAGCAT

Downstream 100 bases:

>100_bases
TAAGTACAAGTCGAGAAATGAGAGTATGGTTTTGATAAAAGTGATTATGGAACAAGTTTTTTCTGTATCTTATATTAGTA
ATAAAATGCGTTACATTGTT

Product: phage integrase family site specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKDQKLCIVVNEWVSWIKKERRYATNTVDSYLRDVNKFIEFLYMCVLRPVTLEDIIGVKVADLRKWFAFRYQANIEAVTN
ARSLSALKNFFRYLSRTYNIDGQAVFCLSRPKLKSTLPRTLTQSHIQKIIDYYALLDTDWIVKRDFALIVLLYGCGLRIS
EAVNLKFQNIRREELLIIGKRSKERILPILPIVRQSLDEYVRCCPYHMELNSVKNEYVFVGVRGKKLKRTYFANRIQKIC
KEIGLPDVITPHAFRHSFATHLFLGGADIRSIQELLGHANLSTTQIYTHLDHKSVIDHYKNFHPQVIKKNS

Sequences:

>Translated_311_residues
MKDQKLCIVVNEWVSWIKKERRYATNTVDSYLRDVNKFIEFLYMCVLRPVTLEDIIGVKVADLRKWFAFRYQANIEAVTN
ARSLSALKNFFRYLSRTYNIDGQAVFCLSRPKLKSTLPRTLTQSHIQKIIDYYALLDTDWIVKRDFALIVLLYGCGLRIS
EAVNLKFQNIRREELLIIGKRSKERILPILPIVRQSLDEYVRCCPYHMELNSVKNEYVFVGVRGKKLKRTYFANRIQKIC
KEIGLPDVITPHAFRHSFATHLFLGGADIRSIQELLGHANLSTTQIYTHLDHKSVIDHYKNFHPQVIKKNS
>Mature_311_residues
MKDQKLCIVVNEWVSWIKKERRYATNTVDSYLRDVNKFIEFLYMCVLRPVTLEDIIGVKVADLRKWFAFRYQANIEAVTN
ARSLSALKNFFRYLSRTYNIDGQAVFCLSRPKLKSTLPRTLTQSHIQKIIDYYALLDTDWIVKRDFALIVLLYGCGLRIS
EAVNLKFQNIRREELLIIGKRSKERILPILPIVRQSLDEYVRCCPYHMELNSVKNEYVFVGVRGKKLKRTYFANRIQKIC
KEIGLPDVITPHAFRHSFATHLFLGGADIRSIQELLGHANLSTTQIYTHLDHKSVIDHYKNFHPQVIKKNS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=33.5593220338983, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1790244, Length=301, Percent_Identity=31.2292358803987, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790768, Length=174, Percent_Identity=30.4597701149425, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36445; Mature: 36445

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDQKLCIVVNEWVSWIKKERRYATNTVDSYLRDVNKFIEFLYMCVLRPVTLEDIIGVKV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHH
ADLRKWFAFRYQANIEAVTNARSLSALKNFFRYLSRTYNIDGQAVFCLSRPKLKSTLPRT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
LTQSHIQKIIDYYALLDTDWIVKRDFALIVLLYGCGLRISEAVNLKFQNIRREELLIIGK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCEEEEEC
RSKERILPILPIVRQSLDEYVRCCPYHMELNSVKNEYVFVGVRGKKLKRTYFANRIQKIC
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
KEIGLPDVITPHAFRHSFATHLFLGGADIRSIQELLGHANLSTTQIYTHLDHKSVIDHYK
HHCCCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHH
NFHPQVIKKNS
CCCCCCCCCCC
>Mature Secondary Structure
MKDQKLCIVVNEWVSWIKKERRYATNTVDSYLRDVNKFIEFLYMCVLRPVTLEDIIGVKV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHH
ADLRKWFAFRYQANIEAVTNARSLSALKNFFRYLSRTYNIDGQAVFCLSRPKLKSTLPRT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
LTQSHIQKIIDYYALLDTDWIVKRDFALIVLLYGCGLRISEAVNLKFQNIRREELLIIGK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCEEEEEC
RSKERILPILPIVRQSLDEYVRCCPYHMELNSVKNEYVFVGVRGKKLKRTYFANRIQKIC
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHCCCCCEEEEEECCCHHHHHHHHHHHHHHH
KEIGLPDVITPHAFRHSFATHLFLGGADIRSIQELLGHANLSTTQIYTHLDHKSVIDHYK
HHCCCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHH
NFHPQVIKKNS
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]