BacMap

Definition	Ehrlichia chaffeensis str. Arkansas, complete genome.
Accession	NC_007799
Length	1,176,248

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The map label for this gene is znuC

Identifier: 88658222

GI number: 88658222

Start: 859646

End: 860374

Strand: Reverse

Name: znuC

Synonym: ECH_0841

Alternate gene names: 88658222

Gene position: 860374-859646 (Counterclockwise)

Preceding gene: 88658065

Following gene: 88658640

Centisome position: 73.15

GC content: 25.24

Gene sequence:

>729_bases
ATGTTTCATAAGTTATTAAATAAAAGTGAAATTCTTGCATATGATAAAAAGTACGTCAATAACTATATTATAAATGTTGA
AAATCTTTCATTTTTTTATTCTAAAGAAAAAGTTATAGATGATATTAGCTTCCAAGTAAAATTTGGTGAAATTGTTACAA
TTTTAGGTCCAAACGGAGGAGGAAAGACAACATTAATTCGTATTCTGGTTGGGATATACAGAAATTATATAGGAGTTATA
AAATATGCAAAAAATTTTATTATAGGATATTTGCCACAACATTTTAGTGTGAATTCTCTTATTCCAATGACAGTAAAATA
TTTTTTAAATTCTAGTTATACAAAGAGCAAAAGAAAATTGAAGTTAAGTGATGTATTAAAAGACATTAATATTGAAAAAA
TATTAGATCGGCAAATGTCGGAGATATCTCATGGGGAATTACAATTAGTTTTACTTGCAAGATGTTTGATGTTAAATCCT
GATATAATTATTCTAGATGAACCAGTGAGTTGTATGGATGTTAATGCAAAAGATAGCTTTTACAAATTGATCAACAAATT
GATTTCTATATATAATTTAAGTGTAATTATGACTTCTCATGATTTACATTTTGTAATGTCAAATTCTTATCGTGTTATAT
GTATTAATAGGAGTATTTATTGTGAAGGATCTCCAAGTGAGATTGTAAAAAATGAAAAGTTCTTAAAAATGTTTTCATCT
TATGCTTAG

Upstream 100 bases:

>100_bases
TAACTAGTGAATATATTGGGTTTATAGTTGCTATAATTCTTGGTACAGAATATCCTATAGTAGGATGTAATAATATATAA
AAGAGCAAGAGAAGGATTGT

Downstream 100 bases:

>100_bases
TACCTTCTCTAATATAATTTCTTTACTGAATATATTAAGTGTTTTAGTAAGGTATAACATATTACCTTATACCTATCTTT
TTGCTAAAAGATCAATTAGG

Product: putative cation ABC transporter, ATP-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MFHKLLNKSEILAYDKKYVNNYIINVENLSFFYSKEKVIDDISFQVKFGEIVTILGPNGGGKTTLIRILVGIYRNYIGVI
KYAKNFIIGYLPQHFSVNSLIPMTVKYFLNSSYTKSKRKLKLSDVLKDINIEKILDRQMSEISHGELQLVLLARCLMLNP
DIIILDEPVSCMDVNAKDSFYKLINKLISIYNLSVIMTSHDLHFVMSNSYRVICINRSIYCEGSPSEIVKNEKFLKMFSS
YA

Sequences:

>Translated_242_residues
MFHKLLNKSEILAYDKKYVNNYIINVENLSFFYSKEKVIDDISFQVKFGEIVTILGPNGGGKTTLIRILVGIYRNYIGVI
KYAKNFIIGYLPQHFSVNSLIPMTVKYFLNSSYTKSKRKLKLSDVLKDINIEKILDRQMSEISHGELQLVLLARCLMLNP
DIIILDEPVSCMDVNAKDSFYKLINKLISIYNLSVIMTSHDLHFVMSNSYRVICINRSIYCEGSPSEIVKNEKFLKMFSS
YA
>Mature_242_residues
MFHKLLNKSEILAYDKKYVNNYIINVENLSFFYSKEKVIDDISFQVKFGEIVTILGPNGGGKTTLIRILVGIYRNYIGVI
KYAKNFIIGYLPQHFSVNSLIPMTVKYFLNSSYTKSKRKLKLSDVLKDINIEKILDRQMSEISHGELQLVLLARCLMLNP
DIIILDEPVSCMDVNAKDSFYKLINKLISIYNLSVIMTSHDLHFVMSNSYRVICINRSIYCEGSPSEIVKNEKFLKMFSS
YA

Specific function: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI27881501, Length=204, Percent_Identity=28.921568627451, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI30795238, Length=204, Percent_Identity=28.921568627451, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI108773784, Length=182, Percent_Identity=31.3186813186813, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI108773782, Length=182, Percent_Identity=31.3186813186813, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI27262624, Length=201, Percent_Identity=28.8557213930348, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI27262626, Length=201, Percent_Identity=28.8557213930348, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI27436953, Length=206, Percent_Identity=26.6990291262136, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI148612853, Length=209, Percent_Identity=24.4019138755981, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI153792144, Length=216, Percent_Identity=24.0740740740741, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI27881506, Length=220, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI10947137, Length=220, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=220, Percent_Identity=36.3636363636364, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1788761, Length=229, Percent_Identity=25.764192139738, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789593, Length=232, Percent_Identity=26.7241379310345, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87081709, Length=239, Percent_Identity=28.0334728033473, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87081791, Length=222, Percent_Identity=26.5765765765766, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787712, Length=208, Percent_Identity=27.4038461538462, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789891, Length=226, Percent_Identity=26.5486725663717, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786563, Length=190, Percent_Identity=27.3684210526316, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789864, Length=251, Percent_Identity=22.7091633466135, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790739, Length=240, Percent_Identity=24.5833333333333, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789991, Length=229, Percent_Identity=29.2576419213974, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787041, Length=202, Percent_Identity=26.7326732673267, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789962, Length=220, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790190, Length=205, Percent_Identity=27.3170731707317, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788002, Length=195, Percent_Identity=27.1794871794872, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788053, Length=206, Percent_Identity=25.7281553398058, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787500, Length=209, Percent_Identity=25.3588516746411, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787370, Length=219, Percent_Identity=25.5707762557078, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787758, Length=183, Percent_Identity=27.3224043715847, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789032, Length=217, Percent_Identity=28.110599078341, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790544, Length=249, Percent_Identity=23.2931726907631, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789672, Length=233, Percent_Identity=24.0343347639485, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081782, Length=225, Percent_Identity=25.7777777777778, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87082267, Length=213, Percent_Identity=22.5352112676056, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789963, Length=227, Percent_Identity=26.8722466960352, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787089, Length=211, Percent_Identity=23.696682464455, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI48995001, Length=241, Percent_Identity=26.9709543568465, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786698, Length=194, Percent_Identity=23.7113402061856, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786703, Length=187, Percent_Identity=25.1336898395722, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788506, Length=210, Percent_Identity=24.7619047619048, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789751, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=208, Percent_Identity=26.4423076923077, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786975, Length=191, Percent_Identity=27.2251308900524, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787112, Length=239, Percent_Identity=23.0125523012552, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790467, Length=221, Percent_Identity=22.6244343891403, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786872, Length=227, Percent_Identity=25.1101321585903, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994883, Length=214, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790525, Length=205, Percent_Identity=25.3658536585366, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994943, Length=227, Percent_Identity=24.6696035242291, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786398, Length=225, Percent_Identity=22.2222222222222, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=200, Percent_Identity=27.5, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17555800, Length=204, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=256, Percent_Identity=22.265625, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555318, Length=212, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25146777, Length=230, Percent_Identity=23.0434782608696, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532730, Length=199, Percent_Identity=24.1206030150754, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17569081, Length=234, Percent_Identity=27.3504273504274, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=226, Percent_Identity=20.7964601769912, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=226, Percent_Identity=21.2389380530973, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=226, Percent_Identity=20.7964601769912, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532409, Length=197, Percent_Identity=24.3654822335025, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=235, Percent_Identity=27.2340425531915, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320296, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320874, Length=197, Percent_Identity=23.8578680203046, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319856, Length=236, Percent_Identity=28.8135593220339, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24641342, Length=208, Percent_Identity=25.9615384615385, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24661270, Length=178, Percent_Identity=32.0224719101124, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355589, Length=178, Percent_Identity=32.0224719101124, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357907, Length=228, Percent_Identity=27.6315789473684, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666836, Length=219, Percent_Identity=24.2009132420091, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571209, Length=194, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007184, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221500365, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581191, Length=206, Percent_Identity=25.2427184466019, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24581189, Length=206, Percent_Identity=25.2427184466019, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24581193, Length=206, Percent_Identity=25.2427184466019, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24581195, Length=206, Percent_Identity=25.2427184466019, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNUC_EHRCR (Q2GFZ6)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507637.1
- ProteinModelPortal:   Q2GFZ6
- SMR:   Q2GFZ6
- STRING:   Q2GFZ6
- GeneID:   3927007
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0841
- TIGR:   ECH_0841
- eggNOG:   COG1121
- HOGENOM:   HBG758042
- OMA:   DRQMSEI
- PhylomeDB:   Q2GFZ6
- ProtClustDB:   CLSK749566
- BioCyc:   ECHA205920:ECH_0841-MONOMER
- HAMAP:   MF_01725
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017882
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 27901; Mature: 27901

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51298 ZNUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHKLLNKSEILAYDKKYVNNYIINVENLSFFYSKEKVIDDISFQVKFGEIVTILGPNGG
CCHHHCCCCHHHHHHHHHHCEEEEEEECCEEEEHHHHHHCCCEEEEEECEEEEEECCCCC
GKTTLIRILVGIYRNYIGVIKYAKNFIIGYLPQHFSVNSLIPMTVKYFLNSSYTKSKRKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHE
KLSDVLKDINIEKILDRQMSEISHGELQLVLLARCLMLNPDIIILDEPVSCMDVNAKDSF
EHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCHHH
YKLINKLISIYNLSVIMTSHDLHFVMSNSYRVICINRSIYCEGSPSEIVKNEKFLKMFSS
HHHHHHHHHHHHEEEEEEECCEEEEECCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHH
YA
CC
>Mature Secondary Structure
MFHKLLNKSEILAYDKKYVNNYIINVENLSFFYSKEKVIDDISFQVKFGEIVTILGPNGG
CCHHHCCCCHHHHHHHHHHCEEEEEEECCEEEEHHHHHHCCCEEEEEECEEEEEECCCCC
GKTTLIRILVGIYRNYIGVIKYAKNFIIGYLPQHFSVNSLIPMTVKYFLNSSYTKSKRKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHE
KLSDVLKDINIEKILDRQMSEISHGELQLVLLARCLMLNPDIIILDEPVSCMDVNAKDSF
EHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCHHH
YKLINKLISIYNLSVIMTSHDLHFVMSNSYRVICINRSIYCEGSPSEIVKNEKFLKMFSS
HHHHHHHHHHHHEEEEEEECCEEEEECCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHH
YA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA