Click here to switch to the map view.

The map label for this gene is argS

Identifier: 88657836

GI number: 88657836

Start: 537290

End: 539020

Strand: Direct

Name: argS

Synonym: ECH_0537

Alternate gene names: 88657836

Gene position: 537290-539020 (Clockwise)

Preceding gene: 88658443

Following gene: 88658558

Centisome position: 45.68

GC content: 30.04

Gene sequence:

>1731_bases
ATGAATTTAATTAATACTGTTAAAAATTGTATAGTGGAAAAGTTACATATATTAAGTGATAAGAAATTAATAGTGCTGGA
TGATGTTATATTAAGTAAGTTAATAGTTGATTATCCTAATAATCATAATCATGGGGATTTGTATACTAATGCAGCTTTAA
TTTTAAGTAGTCATATAAAAAAAAGTCCACTAGAGATAGCAGAAATTTTACTATCTGAATTTTCTAATATTAAGGAAATA
TCTAGCATTAATGTTGTGAAGCCAGGTTTTATTAATTTTAGTATTTCTCTTTATGTATGGTATGAAGTAGTAGCTTCTAT
TAATATGTTAAAAGAGGGTTTTGCTAATGTTAATATAGGAAATGGACAGAAAGTTAATGTAGAATTTGTTTCTGCGAATC
CTACTGGACCAATGCATATTGGACATGCTCGTGGTGCTATATTTGGTGATGTATTAGCGAATTTATTGGAAAAAGTAGGA
TATCAAGTTGTTAGGGAATATTATATTAATGATGCTGGTACACAAATAGACGTGTTAGTTGAATCTGTATATTTAAGATA
TAAAGAAGCTACAGGTCAAGATATTGTAATAGGCAGTGGGTTGTACCCAGGATTATATTTACGAGAGATAGGAAAGCTTC
TATATGAAAAATATGGGACAGATTTATTAGAGATGAGTTTTGTCCGTAAGATGAAGATTATACGTGATGTATCTCTTGAA
TATCTTATGAATCTTATTAAAGAAGATCTTGCATTGTTGGGAATTGAGCATGATGTTTTTACGTCAGAGGCTGAGTTATT
AAAAAATAATATTGTAGAAAAGTGTGTGAAACTTTTAGAAGATAAGCAATTAATATATTATGGAGTGTTAGAGCAACCAA
AAGGGACAGAAATGCAAAATTGGAAGCCTAGAACACAAATGTTGTTTAAATCTACTGATTTCGGAGATGATGTAGATAGA
GCTTTACAGAAAGTTGATGGTAGTTGGACTTATTTTGCAAACGATATAGCTTATCATTTTGATAAGATATCACGTGGTTT
TCAACATATGATTTTAGAGTTGGGTTCTGACCATATTGGTTATGTAAAAAGATTAAAAGCTGCAGTGAAGGCATTAAGTA
ATAATAATGCTACTGTAGATATAAAATTGCACAATACTGTTAATTTTCTTGATGATGGAGTGCAAGTAAAGATGTCGAAA
AGATCTGGTGAATTTCTAACTATAAGAGATGTTATAGAAAAAGTTGGTAAAGATGTAGTCAGATTTATGATGTTAACTCG
TAAGAGTGATGTAGTTTTGGATTTTGATTTTGCTAAAGTTGTTGAACAATCTAAAAATAATCCAATATTTTATGTACAAT
ATGCTCATGCTCGTGTTTGTTCATTAATGCGTAATGCTCCAAATATTTTAGGAATAGAGGATACGGATTTTTCTGTGTTA
TCTTCAAAGGAAGAAATACTGTTAATTAAGTTACTTGCAAAATGGCCAAATGTAGTTGAGATGTCTGCAAAAACTGCAGA
GCCACATCGCATAACTTTTTATTTAATAGAAGTTGCTGAAGCTTTTCATGTGTTATGGGGATATGGAAATAAGAATGCAA
ATAGACGTTTTATTATAGATAATGATGTTAATCTTACATCTGCAAGGATATATTTGGCTAAATCTGTTGCGTATATTATC
AGTAGTGGGTTAAAAATATTTTCCATAGTTCCTTTAGAGGAAATGCATTAA

Upstream 100 bases:

>100_bases
ATTGTGAGCTAATAAATATTATATTGCTTACTTTTAATATTGGTGGAAAGCTGTATAATGTAGTGGAAGTTATAGTGGAA
ATTATAAGAGATTACTATCG

Downstream 100 bases:

>100_bases
CAGTTGTAGTATATGTTTTTTTAAAGATGTGTTTTAGATAATGTAATTATAATAGAAATAATATACGTAGTATTAGATAC
AGTGTTCTTCCAATAGTCAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNLINTVKNCIVEKLHILSDKKLIVLDDVILSKLIVDYPNNHNHGDLYTNAALILSSHIKKSPLEIAEILLSEFSNIKEI
SSINVVKPGFINFSISLYVWYEVVASINMLKEGFANVNIGNGQKVNVEFVSANPTGPMHIGHARGAIFGDVLANLLEKVG
YQVVREYYINDAGTQIDVLVESVYLRYKEATGQDIVIGSGLYPGLYLREIGKLLYEKYGTDLLEMSFVRKMKIIRDVSLE
YLMNLIKEDLALLGIEHDVFTSEAELLKNNIVEKCVKLLEDKQLIYYGVLEQPKGTEMQNWKPRTQMLFKSTDFGDDVDR
ALQKVDGSWTYFANDIAYHFDKISRGFQHMILELGSDHIGYVKRLKAAVKALSNNNATVDIKLHNTVNFLDDGVQVKMSK
RSGEFLTIRDVIEKVGKDVVRFMMLTRKSDVVLDFDFAKVVEQSKNNPIFYVQYAHARVCSLMRNAPNILGIEDTDFSVL
SSKEEILLIKLLAKWPNVVEMSAKTAEPHRITFYLIEVAEAFHVLWGYGNKNANRRFIIDNDVNLTSARIYLAKSVAYII
SSGLKIFSIVPLEEMH

Sequences:

>Translated_576_residues
MNLINTVKNCIVEKLHILSDKKLIVLDDVILSKLIVDYPNNHNHGDLYTNAALILSSHIKKSPLEIAEILLSEFSNIKEI
SSINVVKPGFINFSISLYVWYEVVASINMLKEGFANVNIGNGQKVNVEFVSANPTGPMHIGHARGAIFGDVLANLLEKVG
YQVVREYYINDAGTQIDVLVESVYLRYKEATGQDIVIGSGLYPGLYLREIGKLLYEKYGTDLLEMSFVRKMKIIRDVSLE
YLMNLIKEDLALLGIEHDVFTSEAELLKNNIVEKCVKLLEDKQLIYYGVLEQPKGTEMQNWKPRTQMLFKSTDFGDDVDR
ALQKVDGSWTYFANDIAYHFDKISRGFQHMILELGSDHIGYVKRLKAAVKALSNNNATVDIKLHNTVNFLDDGVQVKMSK
RSGEFLTIRDVIEKVGKDVVRFMMLTRKSDVVLDFDFAKVVEQSKNNPIFYVQYAHARVCSLMRNAPNILGIEDTDFSVL
SSKEEILLIKLLAKWPNVVEMSAKTAEPHRITFYLIEVAEAFHVLWGYGNKNANRRFIIDNDVNLTSARIYLAKSVAYII
SSGLKIFSIVPLEEMH
>Mature_576_residues
MNLINTVKNCIVEKLHILSDKKLIVLDDVILSKLIVDYPNNHNHGDLYTNAALILSSHIKKSPLEIAEILLSEFSNIKEI
SSINVVKPGFINFSISLYVWYEVVASINMLKEGFANVNIGNGQKVNVEFVSANPTGPMHIGHARGAIFGDVLANLLEKVG
YQVVREYYINDAGTQIDVLVESVYLRYKEATGQDIVIGSGLYPGLYLREIGKLLYEKYGTDLLEMSFVRKMKIIRDVSLE
YLMNLIKEDLALLGIEHDVFTSEAELLKNNIVEKCVKLLEDKQLIYYGVLEQPKGTEMQNWKPRTQMLFKSTDFGDDVDR
ALQKVDGSWTYFANDIAYHFDKISRGFQHMILELGSDHIGYVKRLKAAVKALSNNNATVDIKLHNTVNFLDDGVQVKMSK
RSGEFLTIRDVIEKVGKDVVRFMMLTRKSDVVLDFDFAKVVEQSKNNPIFYVQYAHARVCSLMRNAPNILGIEDTDFSVL
SSKEEILLIKLLAKWPNVVEMSAKTAEPHRITFYLIEVAEAFHVLWGYGNKNANRRFIIDNDVNLTSARIYLAKSVAYII
SSGLKIFSIVPLEEMH

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=499, Percent_Identity=22.4448897795591, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI15149476, Length=609, Percent_Identity=22.0032840722496, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788184, Length=149, Percent_Identity=26.8456375838926, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71985061, Length=606, Percent_Identity=23.9273927392739, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71985068, Length=568, Percent_Identity=24.4718309859155, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320548, Length=631, Percent_Identity=25.5150554675119, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI18859963, Length=595, Percent_Identity=23.3613445378151, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_EHRCR (Q2GGT3)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507350.1
- ProteinModelPortal:   Q2GGT3
- SMR:   Q2GGT3
- STRING:   Q2GGT3
- GeneID:   3927980
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0537
- TIGR:   ECH_0537
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   ECHA205920:ECH_0537-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65310; Mature: 65310

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLINTVKNCIVEKLHILSDKKLIVLDDVILSKLIVDYPNNHNHGDLYTNAALILSSHIK
CCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
KSPLEIAEILLSEFSNIKEISSINVVKPGFINFSISLYVWYEVVASINMLKEGFANVNIG
CCHHHHHHHHHHHHHCHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEECC
NGQKVNVEFVSANPTGPMHIGHARGAIFGDVLANLLEKVGYQVVREYYINDAGTQIDVLV
CCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ESVYLRYKEATGQDIVIGSGLYPGLYLREIGKLLYEKYGTDLLEMSFVRKMKIIRDVSLE
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YLMNLIKEDLALLGIEHDVFTSEAELLKNNIVEKCVKLLEDKQLIYYGVLEQPKGTEMQN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
WKPRTQMLFKSTDFGDDVDRALQKVDGSWTYFANDIAYHFDKISRGFQHMILELGSDHIG
CCCHHHHHEECCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YVKRLKAAVKALSNNNATVDIKLHNTVNFLDDGVQVKMSKRSGEFLTIRDVIEKVGKDVV
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHH
RFMMLTRKSDVVLDFDFAKVVEQSKNNPIFYVQYAHARVCSLMRNAPNILGIEDTDFSVL
HHHHHHCCCCEEEECHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCEECCCCCCHHHH
SSKEEILLIKLLAKWPNVVEMSAKTAEPHRITFYLIEVAEAFHVLWGYGNKNANRRFIID
CCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEE
NDVNLTSARIYLAKSVAYIISSGLKIFSIVPLEEMH
CCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHCC
>Mature Secondary Structure
MNLINTVKNCIVEKLHILSDKKLIVLDDVILSKLIVDYPNNHNHGDLYTNAALILSSHIK
CCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
KSPLEIAEILLSEFSNIKEISSINVVKPGFINFSISLYVWYEVVASINMLKEGFANVNIG
CCHHHHHHHHHHHHHCHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEECC
NGQKVNVEFVSANPTGPMHIGHARGAIFGDVLANLLEKVGYQVVREYYINDAGTQIDVLV
CCCEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ESVYLRYKEATGQDIVIGSGLYPGLYLREIGKLLYEKYGTDLLEMSFVRKMKIIRDVSLE
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YLMNLIKEDLALLGIEHDVFTSEAELLKNNIVEKCVKLLEDKQLIYYGVLEQPKGTEMQN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
WKPRTQMLFKSTDFGDDVDRALQKVDGSWTYFANDIAYHFDKISRGFQHMILELGSDHIG
CCCHHHHHEECCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YVKRLKAAVKALSNNNATVDIKLHNTVNFLDDGVQVKMSKRSGEFLTIRDVIEKVGKDVV
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCEEEEEECCCCCEEEHHHHHHHHHHHHH
RFMMLTRKSDVVLDFDFAKVVEQSKNNPIFYVQYAHARVCSLMRNAPNILGIEDTDFSVL
HHHHHHCCCCEEEECHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCEECCCCCCHHHH
SSKEEILLIKLLAKWPNVVEMSAKTAEPHRITFYLIEVAEAFHVLWGYGNKNANRRFIID
CCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEE
NDVNLTSARIYLAKSVAYIISSGLKIFSIVPLEEMH
CCCCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA